4e887ec371f8343254e9c0ffec8559de pmc_32849170.pdf c067c357232975c2888786f102fa2b57d0685826 pmc_32849170.pdf 2c2e3f212ba33535363b285f9c64a8d5be228f556e45635509de3eed583ce030 pmc_32849170.pdf Title: Harnessing Real-World Data to Inform Decision-Making: Multiple Sclerosis Partners Advancing Technology and Health Solutions (MS PATHS) Subject: Background: Multiple Sclerosis Partners Advancing Technology and Health Solutions (MS PATHS) is the first example of a learning health system in multiple sclerosis (MS). Keywords: learning health system, multiple sclerosis, MS PATHS, digital health technology, standardized brain magnetic resonance imaging Author: Richard A. Rudick Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Thu Aug 6 11:25:03 2020 CEST ModDate: Thu Aug 6 11:29:06 2020 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 15 Encrypted: no Page size: 595.26 x 779.52 pts Page rot: 0 File size: 885815 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- YGWLBF+HelveticaNeueLTStd-Bd Type 1C Custom yes yes no 37 0 XPGGWF+HelveticaNeueLTStd-Lt Type 1C Custom yes yes no 42 0 PIAOFJ+HelveticaNeueLTStd-BdIt Type 1C WinAnsi yes yes no 55 0 LORPFA+HelveticaNeueLTStd-LtIt Type 1C Custom yes yes no 57 0 UOBNRC+HelveticaNeueLTStd-MdIt Type 1C WinAnsi yes yes no 63 0 IGWATM+MTSY Type 1C Custom yes yes yes 78 0 YZGKEF+MinionPro-Bold Type 1C Custom yes yes no 98 0 NFUTIB+MinionPro-Regular Type 1C Custom yes yes no 86 0 KDUJXK+TeX-mathb7 Type 1C Custom yes yes no 127 0 HKOLEY+MinionPro-It Type 1C Custom yes yes no 137 0 Times-Roman Type 1 Standard no no no 157 0 OTFGYN+RMTMI Type 1C Custom yes yes no 159 0 AYJXIO+MTSYB Type 1C Custom yes yes no 188 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2020-11-18 06:10:07 CET RepresentationInformation: pmc_32849170.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2020-08-31 03:35:25 CEST Size: 885815 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 342 FreeObjects: 20 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: Harnessing Real-World Data to Inform Decision-Making: Multiple Sclerosis Partners Advancing Technology and Health Solutions (M匀 倀䄀吀䠀匀㸾൥湤潢樍㘠〠潢樍㰼⽐慲敮琠㔠〠刯乥硴‷‰⁒⽄敳琯獥捴楯渪⸲⽁捴楯港䝯呯⽔楴汥⣾＀䤀渀琀爀漀搀甀挀琀椀漀温㸾൥湤潢樍㈹‰扪഼㰯偡牥湴‵‰⁒⽄敳琯獥捴楯渪⸲㔯䅣瑩潮⽇潔漯偲敶′㠠〠刯呩瑬攨References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Item: Title: Materials and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Children: Item: Title: Initial Design Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: Participating Healthcare Institutions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Item: Title: Patients Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: Procedures Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: Governance Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: Standardization Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: Health Information Exchange Architecture Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: Statistical Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Children: Item: Title: MS PATHS Patient Population Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: Assessment Completion Rates and Data Volume Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: Heterogeneity Observed Across Sites Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: Heterogeneity Relative to Phase 3MS RCTs Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: Research Utilization of LHS Data Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: Data Availability Statement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: Ethics Statement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Item: Title: Author Contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: Funding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: Acknowledgments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Item: Title: Supplementary Material Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7 Item: Title: References Destination: 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Rudick Subject: Background: Multiple Sclerosis Partners Advancing Technology and Health Solutions (MS PATHS) is the first example of a learning health system in multiple sclerosis (MS). 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