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Title:          Obesity attenuates the effect of sleep apnea on active TGF-ß1 levels and tumor aggressiveness in patients with melanoma
Subject:        Scientific Reports, https://doi.org/10.1038/s41598-020-72481-x
Author:         Carolina Cubillos-Zapata 
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      Title: Obesity attenuates the effect of sleep apnea on active TGF-ß1 levels and tumor aggressiveness in patients with melanoma
      Children: 
       Item: 
        Title: Anchor 2
       Item: 
        Title: Anchor 3
       Item: 
        Title: Results
        Children: 
         Item: 
          Title: Active TGF-β1 is increased in moderate-severe OSA patients and correlates with melanoma aggressiveness. 
         Item: 
          Title: Leptin levels and OSA patient characteristics according to obesity. 
         Item: 
          Title: TGF-β1 levels only are related to OSA severity in non-obese patients. 
         Item: 
          Title: In vitro effect of intermittent hypoxia on TGF-β1 expression is modulated by leptin levels. 
       Item: 
        Title: Discussion
       Item: 
        Title: Methods
        Children: 
         Item: 
          Title: Study subjects. 
         Item: 
          Title: Dermatological evaluation. 
         Item: 
          Title: Sleep study. 
         Item: 
          Title: Determination of serum levels of active TGFβ1 and leptin. 
         Item: 
          Title: Cell culture. 
         Item: 
          Title: RNA isolation, quantification, and analysis. 
         Item: 
          Title: Statistical analysis. 
       Item: 
        Title: References
       Item: 
        Title: Acknowledgements
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The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL). </pdfaProperty:description>
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                           <pdfaProperty:description>ISSN for an electronic version of the issue in which the resource occurs. Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version.</pdfaProperty:description>
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                           <pdfaProperty:description>The aggregation type specifies the unit of aggregation for a content collection. Comment PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary. </pdfaProperty:description>
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