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Real world experiences and recommendations from an International Panel Subject: Annals of General Psychiatry, https://doi.org/10.1186/s12991-020-00305-3 Keywords: Schizophrenia,Antipsychotics,Cariprazine,Patient subgroups,Recommendations,Negative symptoms Author: Andrea Fagiolini Creator: Springer Producer: Acrobat Distiller 10.1.8 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Fri Sep 25 16:22:06 2020 CEST ModDate: Sat Sep 26 15:33:45 2020 CEST Tagged: no UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 11 Encrypted: no Page size: 595.276 x 790.866 pts Page rot: 0 File size: 1102622 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- MyriadPro-Regular Type 1C Custom yes no yes 38 0 MyriadPro-Bold Type 1C Custom yes no yes 39 0 MyriadPro-It Type 1C Custom yes no yes 40 0 MyriadPro-Semibold Type 1C Custom yes no yes 41 0 MyriadPro-Light Type 1C Custom yes no yes 43 0 DJCHKM+OpenSans Type 1C WinAnsi yes yes no 342 0 WarnockPro-Regular Type 1C Custom yes no yes 42 0 MyriadPro-Regular2 Type 1C WinAnsi yes no yes 294 0 DMBCKM+STIXMath-Regular Type 1C Custom yes yes yes 71 0 MyriadPro-SemiboldIt Type 1C Custom yes no yes 96 0 DWOIAK+MTSY Type 1C Custom yes yes yes 260 0 MyriadPro-Regular3 Type 1C WinAnsi yes no yes 269 0 ELFRYK+OpenSans-Light Type 1C Custom yes yes no 276 0 ELFRYK+OpenSans-Extrabold Type 1C WinAnsi yes yes no 272 0 ELFRYK+OregonLDOBookSinistral Type 1C WinAnsi yes yes no 282 0 ELFRYK+OpenSans-Bold Type 1C WinAnsi yes yes no 279 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2020-11-18 06:04:50 CET RepresentationInformation: pmc_32999683.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2020-10-05 03:35:24 CEST Size: 1102622 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 429 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Treating schizophrenia with cariprazine: from clinical research to clinical practice. Real world experiences and recommendations from an International Panel Children: Item: Title: Abstract Children: Item: Title: Background: Item: Title: Objective: Item: Title: Methods: Item: Title: Results: Item: Title: Conclusions: Item: Title: Introduction Item: Title: Methodology Item: Title: Results: Data gathering and recommendations Children: Item: Title: Cariprazine: place in therapy, patient characteristics Item: Title: Most frequently used doses of cariprazine in clinical practice Item: Title: Procedures used in switching from other antipsychotics to cariprazine, up-titration and time to observation of beneficial effects: acutemaintenance treatment Item: Title: Use of concomitant medications and duration of therapy by patient groupsetting Children: Item: Title: Patients with insomnia or agitation Item: Title: Partial response to positive or negative symptoms Item: Title: Combination therapy Item: Title: Nature, incidence and management of side effects and the role of treatment adjustmentwithdrawal Item: Title: Recommendations to individualize cariprazine treatment for patients with schizophrenia Item: Title: Conclusions Item: Title: References Info: Title: Treating schizophrenia with cariprazine: from clinical research to clinical practice. Real world experiences and recommendations from an International Panel Author: Andrea Fagiolini Subject: Annals of General Psychiatry, https://doi.org/10.1186/s12991-020-00305-3 Keywords: Schizophrenia,Antipsychotics,Cariprazine,Patient subgroups,Recommendations,Negative symptoms Creator: Springer Producer: Acrobat Distiller 10.1.8 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Fri Sep 25 16:52:06 CEST 2020 ModDate: Sat Sep 26 15:33:45 CEST 2020 ID: 0xd59c813f5ff1c5371fb1c745640e5096, 0x4d660b6e7f2d44f3588b6199ce1b0e21 Filters: FilterPipeline: FlateDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 39 ImageHeight: 39 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 40 ImageHeight: 76 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 81 ImageHeight: 84 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 39 ImageHeight: 74 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 39 ImageHeight: 76 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1100 ImageHeight: 90 ColorSpace: black is zero BitsPerSample: 1 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Name: X Fonts: Type1: Font: BaseFont: MyriadPro-SemiboldIt FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-SemiboldIt Flags: Nonsymbolic, Italic FontBBox: -193, -250, 1164, 972 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: DWOIAK+MTSY FontSubset: true FirstChar: 0 LastChar: 255 FontDescriptor: FontName: DWOIAK+MTSY Flags: Symbolic FontBBox: 0, -954, 1043, 796 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: DJCHKM+OpenSans FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: DJCHKM+OpenSans Flags: Nonsymbolic FontBBox: -550, -271, 1204, 1048 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MyriadPro-Regular FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Regular Flags: Nonsymbolic FontBBox: -157, -250, 1126, 952 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-Bold FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Bold Flags: Nonsymbolic FontBBox: -163, -250, 1256, 989 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: DMBCKM+STIXMath-Regular FontSubset: true FirstChar: 31 LastChar: 32 FontDescriptor: FontName: DMBCKM+STIXMath-Regular Flags: Serif, Nonsymbolic FontBBox: -970, -524, 3238, 2566 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-It FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-It Flags: Nonsymbolic, Italic FontBBox: -185, -250, 1090, 953 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-Semibold FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Semibold Flags: Nonsymbolic FontBBox: -161, -250, 1198, 972 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: WarnockPro-Regular FirstChar: 0 LastChar: 255 FontDescriptor: FontName: WarnockPro-Regular Flags: Serif, Nonsymbolic FontBBox: -177, -533, 1474, 950 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-Light FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Light Flags: Nonsymbolic FontBBox: -49, -250, 1046, 883 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true XMP: 2020-09-25T19:52:06+05:30 Springer 2020-09-26T15:33:45+02:00 2020-09-26T15:33:45+02:00 Acrobat Distiller 10.1.8 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) Schizophrenia,Antipsychotics,Cariprazine,Patient subgroups,Recommendations,Negative symptoms application/pdf https://doi.org/10.1186/s12991-020-00305-3 BioMed Central Annals of General Psychiatry, https://doi.org/10.1186/s12991-020-00305-3 Schizophrenia Antipsychotics Cariprazine Patient subgroups Recommendations Negative symptoms Treating schizophrenia with cariprazine: from clinical research to clinical practice. Real world experiences and recommendations from an International Panel Andrea Fagiolini José Ángel Alcalá Thomas Aubel Wojciech Bienkiewicz Mats Magnus Knut Bogren Joaquim Gago Giancarlo Cerveri Michael Colla Francisco Collazos Sanchez Alessandro Cuomo Frieling Helge Eduardo Iacoponi Per-Axel Karlsson Pradeep Peddu Mauro Pettorruso Henrique Jorge Ramos Pereira Johan Sahlsten Schölin Ingo Bernd Vernaleken 10.1186/s12991-020-00305-3 2010-04-23 true springer.com springerlink.com https://doi.org/10.1186/s12991-020-00305-3 10.1186/s12991-020-00305-3 1744-859X journal Annals of General Psychiatry The Author(s) 2010-04-23 true 10.1186/s12991-020-00305-3 noindex springer.com springerlink.com VoR uuid:93b5cce7-8816-4161-b0c3-0a8d2f88fef5 uuid:8f297835-6c57-47f2-a67f-50bfc7129a4d default 1 converted uuid:5ebcb70b-d60b-459e-b005-891fe4ccfbdb converted to PDF/A-2b pdfToolbox 2020-09-25T19:54:26+05:30 2 B Andrea Fagiolini http://orcid.org/0000-0001-5827-0853 http://ns.adobe.com/pdfx/1.3/ pdfx Adobe Document Info PDF eXtension Schema external Mirrors crossmark:MajorVersionDate CrossmarkMajorVersionDate Text external Mirrors crossmark:CrossmarkDomainExclusive CrossmarkDomainExclusive Text internal Mirrors crossmark:DOI doi Text external Mirrors crossmark:CrosMarkDomains CrossMarkDomains seq Text internal A name object indicating whether the document has been modified to include trapping information robots Text internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text http://crossref.org/crossmark/1.0/ crossmark Crossmark Schema internal Usual same as prism:doi DOI Text external The date when a publication was publishe. 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