eaa5e5912027560be4008e154fe51d26  pmc_33323479.pdf
5b6f8e1c57e7d367e3a97e77b5fb66d742586c10  pmc_33323479.pdf
656b9503d78910a3d6507f71de381c20327e4e25c9a9cce953ea38e28e1ec011  pmc_33323479.pdf

Creator:         Adobe InDesign 14.0 (Windows)
Producer:        Adobe PDF Library 15.0
CreationDate:    Wed Dec 30 21:03:32 2020 CET
ModDate:         Wed Dec 30 21:03:33 2020 CET
Custom Metadata: yes
Metadata Stream: yes
Tagged:          no
UserProperties:  no
Suspects:        no
Form:            none
JavaScript:      no
Pages:           5
Encrypted:       no
Page size:       595.276 x 793.701 pts
Page rot:        0
File size:       1524792 bytes
Optimized:       yes
PDF version:     1.4


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
KKUFZZ+FrutigerLTPro-Condensed       Type 1C           Custom           yes yes yes    265  0
CRBWWP+FrutigerLTPro-LightCn         Type 1C           Custom           yes yes yes    266  0
RYRIYL+FrutigerLTPro-BoldCn          Type 1C           WinAnsi          yes yes yes    267  0
UFAAOF+FrutigerLTPro-LightCnIta      Type 1C           Custom           yes yes yes    268  0
NKYIPT+Symbol                        Type 1C           Custom           yes yes yes    288  0
TTASVH+ClassicalGaramondBT-Roman     TrueType          WinAnsi          yes yes yes    284  0
CRBWWP+FrutigerLTPro-LightCn         Type 1C           Custom           yes yes yes    316  0
UFAAOF+FrutigerLTPro-LightCnIta      Type 1C           Custom           yes yes yes    318  0
RYRIYL+FrutigerLTPro-BoldCn          Type 1C           WinAnsi          yes yes yes    320  0
MGOCBV+ClassicalGaramondBT-Italic    TrueType          WinAnsi          yes yes yes    222  0
CRBWWP+FrutigerLTPro-LightCn         Type 1C           Custom           yes yes yes    224  0
UFAAOF+FrutigerLTPro-LightCnIta      Type 1C           Custom           yes yes yes    220  0
RYRIYL+FrutigerLTPro-BoldCn          Type 1C           WinAnsi          yes yes yes    229  0
CRBWWP+FrutigerLTPro-LightCn         Type 1C           Custom           yes yes yes    234  0
UFAAOF+FrutigerLTPro-LightCnIta      Type 1C           Custom           yes yes yes    230  0
RYRIYL+FrutigerLTPro-BoldCn          Type 1C           WinAnsi          yes yes yes    233  0


Jhove (Rel. 1.28.0, 2023-05-18)
 Date: 2024-10-02 04:00:25 CEST
 RepresentationInformation: pmc_33323479.pdf
  ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16)
  LastModified: 2023-03-31 11:47:40 CEST
  Size: 1524792
  Format: PDF
  Version: 1.4
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  Profile: Linearized PDF
  PDFMetadata: 
   Objects: 337
   FreeObjects: 1
   IncrementalUpdates: 1
   DocumentCatalog: 
    ViewerPreferences: 
     HideToolbar: false
     HideMenubar: false
     HideWindowUI: false
     FitWindow: false
     CenterWindow: false
     DisplayDocTitle: false
     NonFullScreenPageMode: UseNone
     Direction: L2R
     ViewArea: CropBox
     ViewClip: CropBox
     PrintArea: CropBox
     PageClip: CropBox
    PageLayout: SinglePage
    PageMode: UseNone
    Language: en-US
    Outlines: 
     Item: 
      Title: Are mesenchymal stem cells and derived extracellular vesicles valuable to halt the COVID-19 inflammatory cascade? Current evidence and future perspectives
      Children: 
       Item: 
        Title: References
   Info: 
    Creator: Adobe InDesign 14.0 (Windows)
    Producer: Adobe PDF Library 15.0
    CreationDate: Wed Dec 30 21:03:32 CET 2020
    ModDate: Wed Dec 30 21:03:33 CET 2020
   ID: 0xbbfc13a07bf23a459d22ecbede390409, 0x9afccf2b7c24e34e95d17264bbb910bb
   Filters: 
    FilterPipeline: FlateDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1419
      ImageHeight: 1217
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1423
      ImageHeight: 954
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Name: X
   Fonts: 
    Type1: 
     Font: 
      BaseFont: NKYIPT+Symbol
      FontSubset: true
      FirstChar: 29
      LastChar: 31
      FontDescriptor: 
       FontName: NKYIPT+Symbol
       Flags: Symbolic
       FontBBox: -180, -293, 1090, 1010
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: KKUFZZ+FrutigerLTPro-Condensed
      FontSubset: true
      FirstChar: 29
      LastChar: 121
      FontDescriptor: 
       FontName: KKUFZZ+FrutigerLTPro-Condensed
       Flags: Nonsymbolic
       FontBBox: -105, -250, 1000, 929
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: CRBWWP+FrutigerLTPro-LightCn
      FontSubset: true
      FirstChar: 29
      LastChar: 252
      FontDescriptor: 
       FontName: CRBWWP+FrutigerLTPro-LightCn
       Flags: Nonsymbolic
       FontBBox: -100, -250, 1000, 919
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: RYRIYL+FrutigerLTPro-BoldCn
      FontSubset: true
      FirstChar: 32
      LastChar: 119
      FontDescriptor: 
       FontName: RYRIYL+FrutigerLTPro-BoldCn
       Flags: Nonsymbolic
       FontBBox: -112, -250, 1000, 940
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: UFAAOF+FrutigerLTPro-LightCnIta
      FontSubset: true
      FirstChar: 31
      LastChar: 121
      FontDescriptor: 
       FontName: UFAAOF+FrutigerLTPro-LightCnIta
       Flags: Nonsymbolic
       FontBBox: -161, -250, 991, 919
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
    TrueType: 
     Font: 
      BaseFont: TTASVH+ClassicalGaramondBT-Roman
      FontSubset: true
      FirstChar: 32
      LastChar: 150
      FontDescriptor: 
       FontName: TTASVH+ClassicalGaramondBT-Roman
       Flags: Serif, Nonsymbolic
       FontBBox: -166, -237, 1261, 963
       FontFile2: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: MGOCBV+ClassicalGaramondBT-Italic
      FontSubset: true
      FirstChar: 32
      LastChar: 116
      FontDescriptor: 
       FontName: MGOCBV+ClassicalGaramondBT-Italic
       Flags: Serif, Nonsymbolic
       FontBBox: -167, -237, 1275, 963
       FontFile2: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="Adobe XMP Core 5.6-c148 79.163765, 2019/01/24-18:11:46        ">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about=""
            xmlns:dc="http://purl.org/dc/elements/1.1/"
            xmlns:xmp="http://ns.adobe.com/xap/1.0/"
            xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/"
            xmlns:stRef="http://ns.adobe.com/xap/1.0/sType/ResourceRef#"
            xmlns:stEvt="http://ns.adobe.com/xap/1.0/sType/ResourceEvent#"
            xmlns:pdfx="http://ns.adobe.com/pdfx/1.3/"
            xmlns:pdf="http://ns.adobe.com/pdf/1.3/">
         <dc:identifier>doi:thoraxjnl-2020-215717</dc:identifier>
         <dc:format>application/pdf</dc:format>
         <xmp:CreateDate>2020-12-30T20:03:32Z</xmp:CreateDate>
         <xmp:MetadataDate>2020-12-30T20:03:33Z</xmp:MetadataDate>
         <xmp:ModifyDate>2020-12-30T20:03:33Z</xmp:ModifyDate>
         <xmp:CreatorTool>Adobe InDesign 14.0 (Windows)</xmp:CreatorTool>
         <xmpMM:InstanceID>uuid:48b9875e-b69e-4225-ab63-3e92120669ff</xmpMM:InstanceID>
         <xmpMM:OriginalDocumentID>xmp.did:AC6A3D891B2068118C14E2BA4B787437</xmpMM:OriginalDocumentID>
         <xmpMM:DocumentID>xmp.id:0c58903b-821f-8d47-8234-e1dbb811b96a</xmpMM:DocumentID>
         <xmpMM:RenditionClass>proof:pdf</xmpMM:RenditionClass>
         <xmpMM:DerivedFrom rdf:parseType="Resource">
            <stRef:instanceID>xmp.iid:8d680811-a80c-d64d-9ea8-0048b7069885</stRef:instanceID>
            <stRef:documentID>xmp.did:d7bc2db9-903e-4e41-a540-3ba22579fa42</stRef:documentID>
            <stRef:originalDocumentID>xmp.did:AC6A3D891B2068118C14E2BA4B787437</stRef:originalDocumentID>
            <stRef:renditionClass>default</stRef:renditionClass>
         </xmpMM:DerivedFrom>
         <xmpMM:History>
            <rdf:Seq>
               <rdf:li rdf:parseType="Resource">
                  <stEvt:action>converted</stEvt:action>
                  <stEvt:parameters>from application/x-indesign to application/pdf</stEvt:parameters>
                  <stEvt:softwareAgent>Adobe InDesign CC 14.0 (Windows)</stEvt:softwareAgent>
                  <stEvt:changed>/</stEvt:changed>
                  <stEvt:when>2020-12-30T20:03:32Z</stEvt:when>
               </rdf:li>
            </rdf:Seq>
         </xmpMM:History>
         <pdfx:jobID>05a56a7d-b8f5-4035-86b7-2979c36f9d6a</pdfx:jobID>
         <pdf:Producer>Adobe PDF Library 15.0</pdf:Producer>
         <pdf:Trapped>False</pdf:Trapped>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Label: 196
     Sequence: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 40, 171, 136, 148
      Annotation: 
       Subtype: Link
       Rect: 335, 575, 343, 565
       ActionDest: 61
      Annotation: 
       Subtype: Link
       Rect: 264, 553, 267, 543
       ActionDest: 61
      Annotation: 
       Subtype: Link
       Rect: 336, 531, 340, 521
       ActionDest: 61
      Annotation: 
       Subtype: Link
       Rect: 339, 498, 343, 488
       ActionDest: 61
      Annotation: 
       Subtype: Link
       Rect: 473, 586, 503, 576
       ActionDest: 251
      Annotation: 
       Subtype: Link
       Rect: 508, 586, 517, 576
       ActionDest: 61
      Annotation: 
       Subtype: Link
       Rect: 413, 542, 417, 532
       ActionDest: 61
      Annotation: 
       Subtype: Link
       Rect: 491, 498, 502, 488
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 546, 454, 553, 444
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 63, 36, 82, 18
      Annotation: 
       Subtype: Link
       Rect: 529, 34, 555, 18
    Page: 
     Label: 197
     Sequence: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 245, 670, 249, 659
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 272, 549, 288, 538
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 86, 494, 93, 483
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 68, 450, 82, 439
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 133, 362, 149, 351
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 201, 285, 208, 274
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 102, 186, 121, 175
       ActionDest: 61
      Annotation: 
       Subtype: Link
       Rect: 127, 186, 155, 175
       ActionDest: 251
      Annotation: 
       Subtype: Link
       Rect: 225, 153, 237, 142
       ActionDest: 61
      Annotation: 
       Subtype: Link
       Rect: 122, 87, 129, 76
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 440, 747, 446, 736
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 439, 714, 453, 703
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 517, 637, 547, 626
       ActionDest: 46
      Annotation: 
       Subtype: Link
       Rect: 444, 560, 451, 549
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 350, 483, 366, 472
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 365, 450, 372, 439
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 474, 428, 480, 417
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 546, 307, 553, 296
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 515, 296, 522, 285
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 332, 175, 347, 164
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 525, 153, 532, 142
       ActionDest: 106
    Page: 
     Label: 198
     Sequence: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 68, 230, 74, 219
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 151, 197, 157, 186
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 122, 120, 137, 109
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 400, 318, 414, 307
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 498, 186, 505, 175
       ActionDest: 106
    Page: 
     Label: 199
     Sequence: 4
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 221, 725, 228, 714
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 218, 692, 233, 681
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 214, 648, 221, 637
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 282, 615, 288, 604
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 59, 527, 65, 516
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 188, 439, 195, 428
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 74, 406, 81, 395
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 141, 340, 148, 329
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 223, 296, 238, 285
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 138, 263, 144, 252
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 82, 175, 89, 164
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 85, 87, 91, 76
       ActionDest: 106
      Annotation: 
       Subtype: Link
       Rect: 376, 258, 511, 248
      Annotation: 
       Subtype: Link
       Rect: 333, 200, 350, 191
      Annotation: 
       Subtype: Link
       Rect: 507, 191, 523, 182
      Annotation: 
       Subtype: Link
       Rect: 436, 163, 507, 154
      Annotation: 
       Subtype: Link
       Rect: 440, 136, 470, 127
      Annotation: 
       Subtype: Link
       Rect: 504, 126, 524, 118
      Annotation: 
       Subtype: Link
       Rect: 371, 99, 405, 90
      Annotation: 
       Subtype: Link
       Rect: 410, 71, 438, 62
      Annotation: 
       Subtype: Link
       Rect: 389, 53, 434, 44
    Page: 
     Label: 200
     Sequence: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 221, 737, 263, 729
      Annotation: 
       Subtype: Link
       Rect: 266, 710, 281, 702
      Annotation: 
       Subtype: Link
       Rect: 54, 701, 78, 693
      Annotation: 
       Subtype: Link
       Rect: 87, 683, 158, 675
      Annotation: 
       Subtype: Link
       Rect: 88, 665, 154, 657
      Annotation: 
       Subtype: Link
       Rect: 177, 638, 220, 630
      Annotation: 
       Subtype: Link
       Rect: 54, 593, 284, 585
      Annotation: 
       Subtype: Link
       Rect: 54, 584, 86, 576
      Annotation: 
       Subtype: Link
       Rect: 72, 566, 121, 558
      Annotation: 
       Subtype: Link
       Rect: 201, 539, 251, 531
      Annotation: 
       Subtype: Link
       Rect: 124, 512, 142, 504
      Annotation: 
       Subtype: Link
       Rect: 124, 494, 169, 486
      Annotation: 
       Subtype: Link
       Rect: 137, 476, 179, 468
      Annotation: 
       Subtype: Link
       Rect: 94, 458, 105, 450
      Annotation: 
       Subtype: Link
       Rect: 210, 440, 246, 432
      Annotation: 
       Subtype: Link
       Rect: 114, 413, 145, 405
      Annotation: 
       Subtype: Link
       Rect: 146, 386, 196, 378
      Annotation: 
       Subtype: Link
       Rect: 85, 359, 117, 351
      Annotation: 
       Subtype: Link
       Rect: 268, 314, 282, 306
      Annotation: 
       Subtype: Link
       Rect: 54, 305, 65, 297
      Annotation: 
       Subtype: Link
       Rect: 245, 287, 279, 279
      Annotation: 
       Subtype: Link
       Rect: 54, 278, 92, 270
      Annotation: 
       Subtype: Link
       Rect: 201, 260, 233, 252
      Annotation: 
       Subtype: Link
       Rect: 54, 233, 120, 225
      Annotation: 
       Subtype: Link
       Rect: 154, 215, 213, 207
      Annotation: 
       Subtype: Link
       Rect: 245, 197, 263, 189
      Annotation: 
       Subtype: Link
       Rect: 235, 170, 286, 162
      Annotation: 
       Subtype: Link
       Rect: 54, 161, 69, 153
      Annotation: 
       Subtype: Link
       Rect: 123, 134, 155, 126
      Annotation: 
       Subtype: Link
       Rect: 416, 728, 466, 720
      Annotation: 
       Subtype: Link
       Rect: 465, 692, 497, 684
      Annotation: 
       Subtype: Link
       Rect: 382, 665, 432, 657
      Annotation: 
       Subtype: Link
       Rect: 504, 647, 530, 639
      Annotation: 
       Subtype: Link
       Rect: 319, 602, 370, 594
      Annotation: 
       Subtype: Link
       Rect: 475, 575, 540, 567
      Annotation: 
       Subtype: Link
       Rect: 319, 566, 527, 558
      Annotation: 
       Subtype: Link
       Rect: 319, 557, 384, 549
      Annotation: 
       Subtype: Link
       Rect: 429, 539, 537, 531
      Annotation: 
       Subtype: Link
       Rect: 319, 530, 460, 522
      Annotation: 
       Subtype: Link
       Rect: 377, 512, 410, 504
      Annotation: 
       Subtype: Link
       Rect: 458, 494, 526, 486
      Annotation: 
       Subtype: Link
       Rect: 487, 458, 520, 450
      Annotation: 
       Subtype: Link
       Rect: 512, 431, 525, 423
      Annotation: 
       Subtype: Link
       Rect: 503, 404, 551, 396
      Annotation: 
       Subtype: Link
       Rect: 319, 395, 355, 387
      Annotation: 
       Subtype: Link
       Rect: 319, 368, 360, 360
      Annotation: 
       Subtype: Link
       Rect: 500, 350, 541, 342
      Annotation: 
       Subtype: Link
       Rect: 350, 323, 367, 315
      Annotation: 
       Subtype: Link
       Rect: 436, 305, 468, 297
      Annotation: 
       Subtype: Link
       Rect: 378, 278, 412, 270
      Annotation: 
       Subtype: Link
       Rect: 497, 260, 537, 252
      Annotation: 
       Subtype: Link
       Rect: 319, 233, 342, 225
      Annotation: 
       Subtype: Link
       Rect: 497, 215, 537, 207
      Annotation: 
       Subtype: Link
       Rect: 494, 188, 534, 180
      Annotation: 
       Subtype: Link
       Rect: 484, 161, 518, 153
  Checksum: 27e64193
   Type: CRC32
  Checksum: eaa5e5912027560be4008e154fe51d26
   Type: MD5
  Checksum: 5b6f8e1c57e7d367e3a97e77b5fb66d742586c10
   Type: SHA-1
  Checksum: 656b9503d78910a3d6507f71de381c20327e4e25c9a9cce953ea38e28e1ec011
   Type: SHA-256