2503e967226f766c75459d119aabab07 pmc_33379281.pdf f678febb135dda18cf2ffabb2bca4e6e26fddd53 pmc_33379281.pdf 0442a1e8f7ed786ebbdc381870a4a834c6c250735ea3c665b267f0a39f95e984 pmc_33379281.pdf Title: Zika Virus Infection in Tourists Travelling to Thailand: Case Series Report Subject: Thailand is a popular tourist destination where Zika virus (ZIKV) transmission is currently active. To our knowledge, there are no reports of ZIKV infection imported from Thailand and affecting children. Here, we describe the clinical and microbiological findings in three cases of vector-borne ZIKV infection: An 11-year-old boy, a 2-year-old girl, and her pregnant mother, this last case leading to the prenatal exposure of her second baby to ZIKV in the second trimester of pregnancy. All patients were diagnosed after traveling to Thailand between September 2019 and January 2020. No complications were detected in any patient at follow-up, and the prenatally exposed fetus showed no abnormalities during intensive antenatal health care monitoring. On postnatal study, there were no clinical signs or microbiological findings of mother-to-child ZIKV transmission. ZIKV IgG was initially positive, but seroreversion occurred at 4 months of life. This report describes the clinical and serological evolution of vector-borne ZIKV infection occurring in dengue-naïve tourists returning from Thailand. The World Health Organization currently recommends that pre-travel advice to prevent arbovirus infection should be maintained in travelers to Southeast Asia. Keywords: zika virus; zika virus infection; mosquito-borne disease; travel; travel-associated; children; neonate; mother-to-child transmission; Thailand Author: Natàlia Romaní, Marie Antoinette Frick, Elena Sulleiro, Carlota Rodó, María Espiau, Diana Pou, Aroa Silgado, Anna Suy, Tomás Pumarola, Pere Soler-Palacín and Antoni Soriano-Arandes Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Tue Dec 29 02:01:50 2020 CET ModDate: Tue Dec 29 02:05:17 2020 CET Custom Metadata: no Metadata Stream: no Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 6 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 418864 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- KPNHET+VnURWPalladioL Type 1 Custom yes yes no 10 0 PDPGOQ+URWPalladioL-Ital Type 1 Custom yes yes no 15 0 EAMTMB+URWPalladioL-Bold Type 1 Custom yes yes no 20 0 IRUCKC+URWPalladioL-Roma Type 1 Custom yes yes no 24 0 HSNKGA+VnURWPalladioL-Bold Type 1 Custom yes yes no 28 0 ZMZZBL+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 36 0 MCBCCI+SourceSansRoman-Regular Type 1C Custom yes yes no 58 0 MCBCCM+SourceSansRoman.613wght Type 1C Custom yes yes no 62 0 MCBCCO+SourceSansRoman-Bold Type 1C Custom yes yes no 66 0 XZFVPS+URWPalladioL-BoldItal Type 1 Custom yes yes no 84 0 FXXUVH+CMSY10 Type 1 Builtin yes yes no 91 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-10-02 04:00:13 CEST RepresentationInformation: pmc_33379281.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2023-03-31 11:47:41 CEST Size: 418864 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 195 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Background Destination: section.1 Item: Title: Case Descriptions Destination: section.2 Children: Item: Title: Rash in a Child on a Flight Returning from Thailand Destination: subsection.2.1 Item: Title: Family Cluster after Travelling to Thailand Destination: subsection.2.2 Item: Title: Discussion Destination: section.3 Item: Title: Conclusions Destination: section.4 Item: Title: References Destination: section.4 Info: Title: Zika Virus Infection in Tourists Travelling to Thailand: Case Series Report Author: Natàlia Romaní, Marie Antoinette Frick, Elena Sulleiro, Carlota Rodó, María Espiau, Diana Pou, Aroa Silgado, Anna Suy, Tomás Pumarola, Pere Soler-Palacín and Antoni Soriano-Arandes Subject: Thailand is a popular tourist destination where Zika virus (ZIKV) transmission is currently active. To our knowledge, there are no reports of ZIKV infection imported from Thailand and affecting children. Here, we describe the clinical and microbiological findings in three cases of vector-borne ZIKV infection: An 11-year-old boy, a 2-year-old girl, and her pregnant mother, this last case leading to the prenatal exposure of her second baby to ZIKV in the second trimester of pregnancy. All patients were diagnosed after traveling to Thailand between September 2019 and January 2020. No complications were detected in any patient at follow-up, and the prenatally exposed fetus showed no abnormalities during intensive antenatal health care monitoring. On postnatal study, there were no clinical signs or microbiological findings of mother-to-child ZIKV transmission. ZIKV IgG was initially positive, but seroreversion occurred at 4 months of life. This report describes the clinical and serological evolution of vector-borne ZIKV infection occurring in dengue-naïve tourists returning from Thailand. The World Health Organization currently recommends that pre-travel advice to prevent arbovirus infection should be maintained in travelers to Southeast Asia. Keywords: zika virus; zika virus infection; mosquito-borne disease; travel; travel-associated; children; neonate; mother-to-child transmission; Thailand Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Tue Dec 29 02:01:50 CET 2020 ModDate: Tue Dec 29 02:05:17 CET 2020 ID: 0xc6effdcc8b30cfc92c6606003def3a43, 0xc6effdcc8b30cfc92c6606003def3a43 Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: EAMTMB+URWPalladioL-Bold FontSubset: true FirstChar: 3 LastChar: 121 FontDescriptor: FontName: EAMTMB+URWPalladioL-Bold Flags: Symbolic FontBBox: -152, -301, 1000, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: XZFVPS+URWPalladioL-BoldItal FontSubset: true FirstChar: 65 LastChar: 121 FontDescriptor: FontName: XZFVPS+URWPalladioL-BoldItal Flags: Symbolic FontBBox: -170, -300, 1073, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: IRUCKC+URWPalladioL-Roma FontSubset: true FirstChar: 2 LastChar: 243 FontDescriptor: 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