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Keywords: microbiome, metagenomics, kernel, supervised, unsupervised, spatio-temporal, SVM, kPCA Author: Elies Ramon Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.15 CreationDate: Sun Jan 24 09:31:14 2021 CET ModDate: Sun Jan 24 09:31:14 2021 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 14 Encrypted: no Page size: 595.276 x 779.528 pts Page rot: 0 File size: 2206199 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- HEYANB+MinionPro-Regular Type 1 Custom yes yes no 25 0 CLJPWK+HelveticaNeueLTStd-Bd Type 1 Custom yes yes no 26 0 TTMCWK+HelveticaNeueLTStd-Lt Type 1 Custom yes yes no 27 0 GMIARM+HelveticaNeueLTStd-BdIt Type 1 Custom yes yes no 32 0 ASSGMG+HelveticaNeueLTStd-LtIt Type 1 Custom yes yes no 33 0 ZGDTJD+HelveticaNeueLTStd-MdIt Type 1 Custom yes yes no 34 0 PWNQSA+MinionPro-Bold Type 1 Custom yes yes no 35 0 FHPRPU+MinionPro-It Type 1 Custom yes yes no 132 0 VJNJOC+RBLMI Type 1 Builtin yes yes no 204 0 TUVJII+MTSYN Type 1 Builtin yes yes no 205 0 LBLEDE+HelveticaNeueLTStd-Md Type 1 Custom yes yes no 209 0 HNWADT+BLEX Type 1 Custom yes yes no 211 0 TABJOA+MTGU Type 1 Builtin yes yes no 212 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2021-02-24 02:24:52 CET RepresentationInformation: FroMic_a2021v12p609048.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2021-02-23 18:19:49 CET Size: 2206199 Format: PDF Version: 1.5 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 786 FreeObjects: 6 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: kernInt: A Kernel Framework for Integrating Supervised and Unsupervised Analyses in Spatio-Temporal Metagenomic Datasets Children: Item: Title: Introduction Item: Title: Materials and Methods Children: Item: Title: Kernels for Microbiome Data Children: Item: Title: Compositional Kernels Item: Title: Non-compositional Kernels Item: Title: Kernel Methods and Framework Item: Title: Spatial Data Item: Title: Temporal Data Item: Title: Microbial Signature Item: Title: Case Studies and Data Pre-processing Children: Item: Title: Soil Dataset Item: Title: Smokers Dataset Item: Title: Pig Dataset Item: Title: Experimental Set-Up Item: Title: Results Children: Item: Title: Soil Data Item: Title: Smokers Data Item: Title: Pig Data Item: Title: Discussion Item: Title: Data Availability Statement Item: Title: Ethics Statement Item: Title: Author Contributions Item: Title: Funding Item: Title: Acknowledgments Item: Title: Supplementary Material Item: Title: References Info: Title: kernInt: A Kernel Framework for Integrating Supervised and Unsupervised Analyses in Spatio-Temporal Metagenomic Datasets Author: Elies Ramon Subject: The advent of next-generation sequencing technologies allowed relative quantification of microbiome communities and their spatial and temporal variation. Keywords: microbiome, metagenomics, kernel, supervised, unsupervised, spatio-temporal, SVM, kPCA Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.15 CreationDate: Sun Jan 24 10:01:14 CET 2021 ModDate: Sun Jan 24 10:01:14 CET 2021 ID: 0x6a2560f4b733e3ca07b17fc079a3b7fd, 0x6a2560f4b733e3ca07b17fc079a3b7fd Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: GMIARM+HelveticaNeueLTStd-BdIt FontSubset: true FirstChar: 42 LastChar: 121 FontDescriptor: FontName: GMIARM+HelveticaNeueLTStd-BdIt Flags: Symbolic FontBBox: -166, -218, 1129, 975 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: ASSGMG+HelveticaNeueLTStd-LtIt FontSubset: true FirstChar: 40 LastChar: 241 FontDescriptor: FontName: ASSGMG+HelveticaNeueLTStd-LtIt Flags: Symbolic FontBBox: -165, -214, 1099, 951 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: ZGDTJD+HelveticaNeueLTStd-MdIt FontSubset: true FirstChar: 42 LastChar: 241 FontDescriptor: FontName: ZGDTJD+HelveticaNeueLTStd-MdIt Flags: Symbolic FontBBox: -165, -218, 1125, 947 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: PWNQSA+MinionPro-Bold FontSubset: true FirstChar: 3 LastChar: 150 FontDescriptor: FontName: PWNQSA+MinionPro-Bold Flags: Symbolic FontBBox: -318, -360, 1684, 917 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: FHPRPU+MinionPro-It FontSubset: true FirstChar: 2 LastChar: 241 FontDescriptor: FontName: FHPRPU+MinionPro-It Flags: Symbolic FontBBox: -201, -360, 1684, 919 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: VJNJOC+RBLMI FontSubset: true FirstChar: 12 LastChar: 62 FontDescriptor: FontName: VJNJOC+RBLMI Flags: Symbolic FontBBox: -11, -230, 987, 750 FontFile: true Font: BaseFont: TUVJII+MTSYN FontSubset: true FirstChar: 0 LastChar: 103 FontDescriptor: FontName: TUVJII+MTSYN Flags: Symbolic FontBBox: 0, -954, 1043, 900 FontFile: true Font: BaseFont: LBLEDE+HelveticaNeueLTStd-Md FontSubset: true FirstChar: 45 LastChar: 119 FontDescriptor: FontName: LBLEDE+HelveticaNeueLTStd-Md Flags: Symbolic FontBBox: -165, -221, 1066, 952 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: HNWADT+BLEX FontSubset: true FirstChar: 0 LastChar: 90 FontDescriptor: FontName: HNWADT+BLEX Flags: Symbolic FontBBox: -23, -2954, 1454, 762 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: TABJOA+MTGU FontSubset: true FirstChar: 98 LastChar: 103 FontDescriptor: FontName: TABJOA+MTGU Flags: Symbolic FontBBox: 25, -213, 839, 683 FontFile: true Font: BaseFont: HEYANB+MinionPro-Regular FontSubset: true FirstChar: 2 LastChar: 246 FontDescriptor: FontName: HEYANB+MinionPro-Regular Flags: Symbolic FontBBox: -289, -360, 1684, 917 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: CLJPWK+HelveticaNeueLTStd-Bd FontSubset: true FirstChar: 40 LastChar: 124 FontDescriptor: FontName: CLJPWK+HelveticaNeueLTStd-Bd Flags: Symbolic FontBBox: -166, -218, 1078, 975 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: TTMCWK+HelveticaNeueLTStd-Lt FontSubset: true FirstChar: 2 LastChar: 124 FontDescriptor: FontName: TTMCWK+HelveticaNeueLTStd-Lt Flags: Symbolic FontBBox: -166, -214, 1050, 967 FontFile: true EncodingDictionary: Differences: true XMP: microbiome, metagenomics, kernel, supervised, unsupervised, spatio-temporal, SVM, kPCA pdfTeX-1.40.15 1.5 application/pdf kernInt: A Kernel Framework for Integrating Supervised and Unsupervised Analyses in Spatio-Temporal Metagenomic Datasets The advent of next-generation sequencing technologies allowed relative quantification of microbiome communities and their spatial and temporal variation. 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