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Keywords: Pompe disease, glycogen storage disease type II, MRI, muscular MRI, respiratory insufficiency, accessory respiratory muscles, diaphragm pillars Author: Jordi Dı́az-Manera Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Wed Feb 24 06:20:15 2021 CET ModDate: Wed Feb 24 06:56:32 2021 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 10 Encrypted: no Page size: 595.26 x 779.52 pts Page rot: 0 File size: 1233791 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- TXQLRY+HelveticaNeueLTStd-Lt Type 1C Custom yes yes no 35 0 PIAOFJ+HelveticaNeueLTStd-BdIt Type 1C WinAnsi yes yes no 48 0 CLRYWI+HelveticaNeueLTStd-LtIt Type 1C Custom yes yes no 50 0 NCJFFP+HelveticaNeueLTStd-MdIt Type 1C WinAnsi yes yes no 55 0 OBAZBH+RMTMI Type 1C WinAnsi yes yes no 57 0 HSJNTL+HelveticaNeueLTStd-Bd Type 1C Custom yes yes no 30 0 AIWWAF+MinionPro-Regular Type 1C Custom yes yes no 65 0 ZZANYS+MinionPro-It Type 1C WinAnsi yes yes no 67 0 YFMHET+MTSY Type 1C Custom yes yes yes 73 0 JUJSDJ+MinionPro-Bold Type 1C Custom yes yes no 108 0 UADLTO+MTSYB Type 1C Custom yes yes no 118 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2021-03-30 02:43:31 CEST RepresentationInformation: 237949.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2021-03-29 09:36:16 CEST Size: 1233791 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 251 FreeObjects: 15 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: Correlation Between Respiratory Accessory Muscles and Diaphragm Pillars MRI and Pulmonary Function Test in Late-Onset Pompe Di猀攀愀猀攀 倀愀琀椀攀渀琀猩㸾൥湤潢樍㘠〠潢樍㰼⽐慲敮琠㔠〠刯乥硴‷‰⁒⽄敳琯獥捴楯渪⸲⽁捴楯港䝯呯⽔楴汥⣾＀䤀渀琀爀漀搀甀挀琀椀漀温㸾൥湤潢樍㈲‰扪഼㰯偡牥湴‵‰⁒⽄敳琯獥捴楯渪⸱㠯䅣瑩潮⽇潔漯偲敶′ㄠ〠刯呩瑬攨References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Item: Title: Materials and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Children: Item: Title: Description of the Study Population and PFT Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: Muscle Imaging Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Item: Title: Statistics Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Children: Item: Title: Cohort Description Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: MRI T1w Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: Pulmonary Function Test Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: Correlation Test Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: Data Availability Statement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: Ethics Statement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: Author Contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: Funding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: Acknowledgments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Info: Title: Correlation Between Respiratory Accessory Muscles and Diaphragm Pillars MRI and Pulmonary Function Test in Late-Onset Pompe Disease Patients Author: Jordi Dı́az-Manera Subject: Objectives: Pompe disease is a rare genetic disease produced by mutations in the GAA gene leading to progressive skeletal and respiratory muscle weakness. Keywords: Pompe disease, glycogen storage disease type II, MRI, muscular MRI, respiratory insufficiency, accessory respiratory muscles, diaphragm pillars Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Wed Feb 24 06:50:15 CET 2021 ModDate: Wed Feb 24 07:26:32 CET 2021 ID: 0x33f9c9a3ec1578811a87f770677b064f, 0x370656245e41ca43b4368832218544a2 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 279 ImageHeight: 279 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1772 ImageHeight: 695 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1771 ImageHeight: 1050 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2008 ImageHeight: 1386 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1772 ImageHeight: 407 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Fonts: Type1: Font: BaseFont: PIAOFJ+HelveticaNeueLTStd-BdIt FontSubset: true FirstChar: 42 LastChar: 121 FontDescriptor: FontName: PIAOFJ+HelveticaNeueLTStd-BdIt Flags: Nonsymbolic FontBBox: -63, -182, 717, 731 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AIWWAF+MinionPro-Regular FontSubset: true FirstChar: 2 LastChar: 243 FontDescriptor: FontName: AIWWAF+MinionPro-Regular Flags: Symbolic FontBBox: -26, -257, 956, 811 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: CLRYWI+HelveticaNeueLTStd-LtIt FontSubset: true FirstChar: 0 LastChar: 243 FontDescriptor: FontName: CLRYWI+HelveticaNeueLTStd-LtIt Flags: Symbolic FontBBox: -137, -206, 978, 729 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: TXQLRY+HelveticaNeueLTStd-Lt FontSubset: true FirstChar: 0 LastChar: 150 FontDescriptor: FontName: TXQLRY+HelveticaNeueLTStd-Lt Flags: Serif, Symbolic FontBBox: -30, -214, 904, 786 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: ZZANYS+MinionPro-It FontSubset: true FirstChar: 40 LastChar: 241 FontDescriptor: FontName: ZZANYS+MinionPro-It Flags: Symbolic FontBBox: -142, -257, 903, 712 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: UADLTO+MTSYB FontSubset: true FirstChar: 68 LastChar: 68 FontDescriptor: FontName: UADLTO+MTSYB Flags: Symbolic, AllCap FontBBox: 0, 0, 724, 387 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: NCJFFP+HelveticaNeueLTStd-MdIt FontSubset: true FirstChar: 42 LastChar: 241 FontDescriptor: FontName: NCJFFP+HelveticaNeueLTStd-MdIt Flags: Symbolic FontBBox: -64, -205, 891, 731 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OBAZBH+RMTMI FontSubset: true FirstChar: 60 LastChar: 62 FontDescriptor: FontName: OBAZBH+RMTMI Flags: Nonsymbolic, AllCap FontBBox: 0, 0, 683, 455 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: YFMHET+MTSY FontSubset: true FirstChar: 0 LastChar: 68 FontDescriptor: FontName: YFMHET+MTSY Flags: Symbolic FontBBox: 0, -209, 944, 679 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: JUJSDJ+MinionPro-Bold FontSubset: true FirstChar: 3 LastChar: 117 FontDescriptor: FontName: JUJSDJ+MinionPro-Bold Flags: Symbolic FontBBox: 0, -244, 660, 703 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: HSJNTL+HelveticaNeueLTStd-Bd FontSubset: true FirstChar: 0 LastChar: 124 FontDescriptor: FontName: HSJNTL+HelveticaNeueLTStd-Bd Flags: Symbolic FontBBox: -19, -214, 925, 786 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true XMP: 2021-02-24T10:50:15+05:30 LaTeX with hyperref package + hypdvips 2021-02-24T11:26:32+05:30 2021-02-24T11:26:32+05:30 application/pdf Objectives: Pompe disease is a rare genetic disease produced by mutations in the GAA gene leading to progressive skeletal and respiratory muscle weakness. 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