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Keywords: overweight, menopause, estrogen, mammogram, adipocytokine, insulin, obesity Author: Laura García-Estévez Creator: Arbortext Advanced Print Publisher 10.0.1306/W Unicode Producer: Acrobat Distiller 7.0 (Windows) CreationDate: Tue Aug 10 10:13:39 2021 CEST ModDate: Tue Aug 10 10:45:50 2021 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 10 Encrypted: no Page size: 595.276 x 779.528 pts Page rot: 0 File size: 636782 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- ABAFHM+AdvOT6601a1b9.BI Type 1C WinAnsi yes yes no 558 0 ABAFHN+AdvOT1deab444.I+01 Type 1C MacRoman yes yes no 559 0 ABAFHO+AdvOT1deab444.I+fb Type 1C Custom yes yes yes 560 0 ABAFEC+AdvOT34fe1490.B Type 1C WinAnsi yes yes no 531 0 ABAFFD+AdvOT34fe1490.B+fb Type 1C Custom yes yes yes 532 0 ABAFFE+AdvOT01861455.I Type 1C WinAnsi yes yes no 533 0 ABAFFF+AdvOT01861455.I+01 Type 1C MacRoman yes yes no 534 0 ABAFFG+AdvPSA18C Type 1C WinAnsi yes yes no 535 0 ABAFFH+AdvOT1deab444.I Type 1C WinAnsi yes yes no 536 0 ABAFFI+AdvPSA323 Type 1C WinAnsi yes yes no 537 0 ABAFFJ+AdvOT1deab444.I+20 Type 1C WinAnsi yes yes no 538 0 ABAFFK+AdvOT6e5d2ec0 Type 1C WinAnsi yes yes no 539 0 ABAFFL+AdvOT6e5d2ec0+fb Type 1C Custom yes yes yes 550 0 ABAFFM+AdvOT1ef757c0 Type 1C WinAnsi yes yes no 551 0 ABAFKO+AdvOT1ef757c0+fb Type 1C Custom yes yes yes 291 0 ABAFKP+AdvOTb65e897d.B Type 1C WinAnsi yes yes no 283 0 ABAFLA+AdvOT1ef757c0+20 Type 1C WinAnsi yes yes no 282 0 ABAFMB+AdvOT1ef757c0+22 Type 1C Custom yes yes yes 275 0 ABAFMC+AdvOT6e5d2ec0+22 Type 1C Custom yes yes yes 286 0 ABAFNC+AdvOT6e5d2ec0+01 Type 1C MacRoman yes yes no 277 0 ABAFPC+AdvOTd877c31c Type 1C WinAnsi yes yes no 293 0 ABAFPD+AdvOT3f84ef53 Type 1C WinAnsi yes yes no 295 0 ABAGAE+AdvOT7d6df7ab.I Type 1C WinAnsi yes yes no 297 0 ABAHFM+AdvTT3713a231+20 Type 1C Custom yes yes yes 300 0 ABAICI+AdvTT58d178b9+03 Type 1C Custom yes yes yes 301 0 ABAIEI+AdvOTb65e897d.B+fb Type 1C Custom yes yes yes 303 0 ABAIEJ+AdvOTb65e897d.B+20 Type 1C WinAnsi yes yes no 304 0 ABAIEK+AdvOT7d6df7ab.I+01 Type 1C MacRoman yes yes no 305 0 ABAIEL+AdvTT02dee1cd.I+03 Type 1C Custom yes yes yes 306 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2022-03-22 02:51:35 CET RepresentationInformation: 249431.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2022-03-21 13:34:16 CET Size: 636782 Format: PDF Version: 1.4 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - 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referenced object 'B75' cannot be found Offset: 611836 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B73' cannot be found Offset: 611836 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B75' cannot be found Offset: 611836 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B73' cannot be found Offset: 611836 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B73' cannot be found Offset: 611836 MIMEtype: application/pdf PDFMetadata: Objects: 621 FreeObjects: 1 IncrementalUpdates: 2 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Obesity and Breast Cancer: A Paradoxical and Controversial Relationship Influenced by Menopausal Status Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@87f383f Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Item: Title: Paradoxical Effects of Body Mass Index on Breast Cancer Risk in Relation to Menopausal Status Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Item: Title: Potential Mechanisms that Could Explain the Paradoxical Relationship Between Obesity and Breast Cancer Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Children: Item: Title: Difference in Estrogen Levels Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: Mammogram Density Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Item: Title: The Role of Adipocytokines Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: Insulin Signaling Pathway Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: Chronic Inflammation Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: Author Contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: Funding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: Acknowledgments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Info: Title: Obesity and Breast Cancer: A Paradoxical and Controversial Relationship Influenced by Menopausal Status Author: Laura García-Estévez Subject: Breast cancer is the most common tumor in women worldwide, and an increasing public health concern. 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Pérez Isabel Calvo Isabel Gallegos Gema Moreno-Bueno Breast cancer is the most common tumor in women worldwide, and an increasing public health concern. overweight menopause estrogen mammogram adipocytokine insulin obesity uuid:8160bb13-eaa1-4c9d-9fa5-d049ba656faf uuid:d3a5278e-8496-4b87-bbda-3448b73bfeb3 Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 175, 603, 470, 624 Annotation: Subtype: Link Rect: 175, 580, 475, 601 Annotation: Subtype: Link Rect: 175, 557, 439, 578 Annotation: Subtype: Link Rect: 175, 534, 366, 555 Annotation: Subtype: Link Rect: 296, 75, 301, 85 Destination: 145 Annotation: Subtype: Link Rect: 45, 29, 108, 36 Annotation: Subtype: Link Rect: 117, 29, 175, 36 Annotation: Subtype: Link Rect: 418, 29, 549, 36 Annotation: Subtype: Link Rect: 87, 414, 158, 422 Annotation: Subtype: Link Rect: 79, 275, 158, 282 Annotation: Subtype: Link Rect: 96, 255, 158, 262 Annotation: Subtype: Link Rect: 62, 64, 158, 71 Annotation: Subtype: Link Rect: 522, 736, 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