b1864b2b353d3c3a2a1533e751d16569  jouneueng_a2021m10v18n5p055002.pdf
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Title:          Characterization of optogenetically-induced cortical spreading depression in awake mice using graphene micro-transistor arrays
Subject:        Journal of Neural Engineering, 18 (2021) 055002 doi: 10.1088/1741-2552/abecf3
Keywords:       graphene,electrophysiology,spreading depression,optogenetics
Author:         Eduard Masvidal-Codina,Trevor M Smith,Daman Rathore,Yunan Gao,Xavi Illa,Elisabet Prats-Alfonso,Elena Del Corro,Andrea Bonaccini Calia,Gemma Rius,Iñigo Martin-Fernandez,Christoph Guger,Patrick Reitner,Rosa Villa,Jose A Garrido,Anton Guimerà-Brunet,Rob C Wykes
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     Item: 
      Title: Characterization of optogenetically-induced cortical spreading depression in awake mice using graphene micro-transistor arrays
      Children: 
       Item: 
        Title: 1. Introduction
       Item: 
        Title: 2. Materials and methods
        Children: 
         Item: 
          Title: 2.1. Animal preparation
         Item: 
          Title: 2.2. Surgeries for viral injection and headbar attachment
         Item: 
          Title: 2.3. Surgeries for craniotomy
         Item: 
          Title: 2.4. Electrophysiological recordings
         Item: 
          Title: 2.5. Determination of light threshold for optogenetically-induced CSD and array calibration
         Item: 
          Title: 2.6. Inclusion criteria
         Item: 
          Title: 2.7. Comparison of CSD induction methods
         Item: 
          Title: 2.8. Pharmacological screen assay
         Item: 
          Title: 2.9. Assays using dual gSGFETs
         Item: 
          Title: 2.10. Transduction volume calculations
         Item: 
          Title: 2.11. gSGFET arrays
         Item: 
          Title: 2.12. Data analysis
         Item: 
          Title: 2.13. CSD parameter extraction
         Item: 
          Title: 2.14. CSD wave propagation direction
         Item: 
          Title: 2.15. CSD band analysis
         Item: 
          Title: 2.16. CSD shape clustering
         Item: 
          Title: 2.17. Statistical analysis and experimental design
       Item: 
        Title: 3. Results
        Children: 
         Item: 
          Title: 3.1. Optogenetic CSD model in awake head-fixed mice
         Item: 
          Title: 3.2. Comparison with more invasive CSD induction methodologies
         Item: 
          Title: 3.3. CSD waveform analysis
         Item: 
          Title: 3.4. Pharmacological suppression of CSD in awake mice
         Item: 
          Title: 3.5. Investigation of CSD induction
         Item: 
          Title: 3.6. Through-skull detection of CSD
       Item: 
        Title: 4. Discussion
       Item: 
        Title: 5. Conclusion
       Item: 
        Title: Acknowledgments
       Item: 
        Title: References
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    Author: Eduard Masvidal-Codina,Trevor M Smith,Daman Rathore,Yunan Gao,Xavi Illa,Elisabet Prats-Alfonso,Elena Del Corro,Andrea Bonaccini Calia,Gemma Rius,Iñigo Martin-Fernandez,Christoph Guger,Patrick Reitner,Rosa Villa,Jose A Garrido,Anton Guimerà-Brunet,Rob C Wykes
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    Keywords: graphene,electrophysiology,spreading depression,optogenetics
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  Checksum: 09ba97d3
   Type: CRC32
  Checksum: b1864b2b353d3c3a2a1533e751d16569
   Type: MD5
  Checksum: 77ff49d51d1243faf338970848adff6166f0cae8
   Type: SHA-1