f1290d03b7a0bdb76b4b8b24c6c3baad 250533.pdf 3171391249a165c40730defe98722f7c0019e5e7 250533.pdf 7dcfeafd9551ce8dcf2bf01d6374c780426fdb920a49cd9e00a2841006e555c3 250533.pdf Title: Proteomic quantitative study of dorsal root ganglia and sciatic nerve in type 2 diabetic mice Subject: Molecular Metabolism, 55 (2022) 101408. doi:10.1016/j.molmet.2021.101408 Author: Marc Leal-Julià Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: 10th January 2022 ModDate: Mon Jan 10 18:30:56 2022 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 13 Encrypted: no Page size: 595.276 x 793.701 pts Page rot: 0 File size: 3275805 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- FMGNAD+AdvOTad521943 Type 1C WinAnsi yes yes no 1041 0 FMGNAE+AdvP4C4E59 Type 1C Custom yes yes yes 1046 0 FMGNAF+AdvOT9d0303c0.B Type 1C WinAnsi yes yes no 1049 0 FMGNAG+AdvOT8e81dcaa Type 1C WinAnsi yes yes no 1052 0 FMGNBH+AdvOTa4800bed.I Type 1C WinAnsi yes yes no 1054 0 FMGNBI+AdvOT8e81dcaa+fb Type 1C Custom yes yes yes 1047 0 FMGNBJ+AdvPSSym Type 1C Custom yes yes no 1066 0 FMGNBK+AdvPS44A44B Type 1C WinAnsi yes yes no 1060 0 FMGNBL+AdvOT8e81dcaa+20 Type 1C WinAnsi yes yes no 1062 0 FMGNBM+AdvP4C4E74 Type 1C Custom yes yes yes 1071 0 FMGNFL+AdvPS3F4C13 Type 1C WinAnsi yes yes no 744 0 FMGNFM+AdvP4C4E51 Type 1C WinAnsi yes yes no 748 0 FMHGIF+AdvOT9d0303c0.B+fb Type 1C Custom yes yes yes 754 0 FMHNFM+AdvTT2876772e+20 Type 1C Custom yes yes yes 765 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2022-03-23 02:24:11 CET RepresentationInformation: 250533.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2022-03-22 09:01:00 CET Size: 3275805 Format: PDF Version: 1.7 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ErrorMessage: Improperly formed date Offset: 3256752 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib5' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib13' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib14' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib15' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'appsec1' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib16' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib17' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib18' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib17' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib17' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib19' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'appsec1' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib20' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib21' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib22' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib23' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib24' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'appsec1' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'appsec1' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'appsec1' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fnd' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fnc' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fna' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fnd' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fnc' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fnb' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fna' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fnb' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fnb' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fnb' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fna' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fnb' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fna' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fna' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fnc' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fnd' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fnc' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fnd' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fnd' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fnb' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fna' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fna' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fna' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fnb' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fnb' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fna' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'tbl1fnb' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'appsec1' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib25' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib26' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib27' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib28' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib29' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'appsec1' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'appsec1' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'appsec1' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'appsec1' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'appsec1' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib30' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib31' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib5' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib32' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib33' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib34' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib34' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib35' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib36' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'appsec1' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib37' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib38' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib39' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib40' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib41' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib42' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib43' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib44' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib45' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib46' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib47' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib48' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib11' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib49' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib45' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib50' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib51' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib5' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib52' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib53' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib54' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib11' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib55' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib56' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib57' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib56' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib56' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib58' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib59' cannot be found Offset: 3240282 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib60' cannot be found Offset: 3240282 MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 1144 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: Proteomic quantitative study of dorsal root ganglia and sciatic nerve in type 2 diabetic mice Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Children: Item: Title: 1. Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Item: Title: 2. Research design and methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Children: Item: Title: 2.1. Animals Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: 2.2. Electrophysiology testing Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Item: Title: 2.3. Sweating test Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: 2.4. Morphometry of tibial nerve Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: 2.5. Cutaneous innervation evaluation Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: 2.6. Immunohistochemistry Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: 2.7. Relative protein quantification using TMT-LC/MS/MS and bioinformatics analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: 2.8. Real time PCR Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: 2.9. Western blot Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: 2.10. Preparation of BSA-conjugated palmitate Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: 2.11. Xbp1 alternative splicing Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: 2.12. Statistical analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: 3. Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Children: Item: Title: 3.1. Peripheral neuropathy profile Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: 3.2. Functional enrichment Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: 3.3. Validation of the proteomic results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: 4. Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Children: Item: Title: 4.1. Oxidative and ER stress Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: 4.2. Metabolic deficiency Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: 4.3. Translational machinery Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Item: Title: 4.4. Cytoskeleton and muscle-like proteins Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7 Item: Title: 4.5. Inflammatory response Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cbd213e Item: Title: 4.6. Major urinary protein Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247 Item: Title: 4.7. DRG and SCN comparison Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3ecd23d9 Item: Title: 4.8. Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@569cfc36 Item: Title: Acknowledgements Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@43bd930a Item: Title: Appendix A. Supplementary data Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@33723e30 Item: Title: Declarations of interest Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@64f6106c Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@553a3d88 Info: Title: Proteomic quantitative study of dorsal root ganglia and sciatic nerve in type 2 diabetic mice Author: Marc Leal-Julià Subject: Molecular Metabolism, 55 (2022) 101408. doi:10.1016/j.molmet.2021.101408 Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) ID: 0xd67021162e28b409cc2175e6863d4419, 0xe46ae1ee8646ce448013a57b6c32174f Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 103 ImageHeight: 102 ColorSpace: palette color BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1422 ImageHeight: 1928 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1778 ImageHeight: 1540 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1659 ImageHeight: 1623 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1659 ImageHeight: 1737 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1778 ImageHeight: 1761 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type1: Font: BaseFont: FMGNBK+AdvPS44A44B FontSubset: true FirstChar: 101 LastChar: 101 FontDescriptor: FontName: FMGNBK+AdvPS44A44B Flags: Nonsymbolic FontBBox: 0, -197, 1000, 802 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: FMGNBL+AdvOT8e81dcaa+20 FontSubset: true FirstChar: 146 LastChar: 148 FontDescriptor: FontName: FMGNBL+AdvOT8e81dcaa+20 Flags: Nonsymbolic FontBBox: -156, -145, 1000, 718 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: FMGNFL+AdvPS3F4C13 FontSubset: true FirstChar: 68 LastChar: 109 FontDescriptor: FontName: FMGNFL+AdvPS3F4C13 Flags: Nonsymbolic FontBBox: 0, -291, 875, 697 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: FMGNBJ+AdvPSSym FontSubset: true FirstChar: 1 LastChar: 4 FontDescriptor: FontName: FMGNBJ+AdvPSSym Flags: Symbolic FontBBox: -177, -291, 1083, 1010 FontFile3: true EncodingDictionary: Differences: true Font: BaseFont: FMGNFM+AdvP4C4E51 FontSubset: true FirstChar: 60 LastChar: 62 FontDescriptor: FontName: FMGNFM+AdvP4C4E51 Flags: Nonsymbolic FontBBox: -31, -239, 1041, 750 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: FMGNBM+AdvP4C4E74 FontSubset: true FirstChar: 1 LastChar: 254 FontDescriptor: FontName: FMGNBM+AdvP4C4E74 Flags: Symbolic FontBBox: -20, -958, 1114, 770 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: FMGNAD+AdvOTad521943 FontSubset: true FirstChar: 40 LastChar: 243 FontDescriptor: FontName: FMGNAD+AdvOTad521943 Flags: Nonsymbolic FontBBox: -31, -229, 802, 968 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: FMHGIF+AdvOT9d0303c0.B+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: FMHGIF+AdvOT9d0303c0.B+fb Flags: Symbolic FontBBox: 0, 0, 500, 718 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: FMGNAE+AdvP4C4E59 FontSubset: true FirstChar: 2 LastChar: 42 FontDescriptor: FontName: FMGNAE+AdvP4C4E59 Flags: Symbolic FontBBox: -31, -250, 1000, 750 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: FMGNBI+AdvOT8e81dcaa+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: FMGNBI+AdvOT8e81dcaa+fb Flags: Symbolic FontBBox: 0, 0, 500, 718 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: FMGNAF+AdvOT9d0303c0.B FontSubset: true FirstChar: 40 LastChar: 121 FontDescriptor: FontName: FMGNAF+AdvOT9d0303c0.B Flags: Nonsymbolic FontBBox: -31, -218, 770, 958 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: FMGNAG+AdvOT8e81dcaa FontSubset: true FirstChar: 35 LastChar: 250 FontDescriptor: FontName: FMGNAG+AdvOT8e81dcaa Flags: Nonsymbolic FontBBox: -31, -208, 770, 927 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: FMHNFM+AdvTT2876772e+20 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: FMHNFM+AdvTT2876772e+20 Flags: Symbolic FontBBox: -218, -197, 1302, 781 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: FMGNBH+AdvOTa4800bed.I FontSubset: true FirstChar: 35 LastChar: 122 FontDescriptor: FontName: FMGNBH+AdvOTa4800bed.I Flags: Nonsymbolic FontBBox: -52, -270, 895, 927 FontFile3: true Encoding: WinAnsiEncoding XMP: application/pdf doi:10.1016/j.molmet.2021.101408 Proteomic quantitative study of dorsal root ganglia and sciatic nerve in type 2 diabetic mice Marc Leal-Julià Jorge J. Vilches Andrea Onieva Sergi Verdés Ángela Sánchez Miguel Chillón Xavier Navarro Assumpció Bosch Diabetes Obesity Neuropathy Proteomics Dorsal root ganglia Sciatic nerve Molecular Metabolism, 55 (2022) 101408. doi:10.1016/j.molmet.2021.101408 The Authors journal Molecular Metabolism © 2021 The Authors. Published by Elsevier GmbH. 2212-8778 55 January 2022 101408 101408 10.1016/j.molmet.2021.101408 https://doi.org/10.1016/j.molmet.2021.101408 2010-04-23 true 10.1016/j.molmet.2021.101408 elsevier.com sciencedirect.com VoR 10.1016/j.molmet.2021.101408 noindex 2010-04-23 true 10th January 2022 sciencedirect.com elsevier.com Elsevier 2022-01-10T23:00:56+05:30 2022-01-10T23:00:56+05:30 True 10th January 2022 Acrobat Distiller 8.1.0 (Windows) uuid:adaa4d89-7cfb-4dcf-aa04-47a8cf26a18d uuid:a2cd8161-6601-4e64-a39c-48e82beb0997 http://creativecommons.org/licenses/by-nc-nd/4.0/ Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 102, 604, 102, 605 Annotation: Subtype: Link Rect: 104, 606, 107, 615 Destination: 953 Annotation: Subtype: Link Rect: 110, 606, 113, 615 Destination: 953 Annotation: Subtype: Link Rect: 115, 606, 119, 615 Destination: 953 Annotation: Subtype: Link Rect: 186, 604, 186, 605 Annotation: Subtype: Link Rect: 188, 606, 192, 615 Destination: 953 Annotation: Subtype: Link Rect: 194, 606, 197, 615 Destination: 953 Annotation: Subtype: Link Rect: 259, 604, 259, 605 Annotation: Subtype: Link Rect: 260, 606, 264, 615 Destination: 953 Annotation: Subtype: Link Rect: 266, 606, 270, 615 Destination: 953 Annotation: Subtype: Link Rect: 272, 606, 276, 615 Destination: 953 Annotation: Subtype: Link Rect: 330, 604, 330, 605 Annotation: Subtype: Link Rect: 331, 606, 335, 615 Destination: 953 Annotation: Subtype: Link Rect: 337, 606, 341, 615 Destination: 953 Annotation: Subtype: Link Rect: 343, 606, 347, 615 Destination: 953 Annotation: Subtype: Link Rect: 413, 604, 413, 605 Annotation: Subtype: Link Rect: 415, 606, 419, 615 Destination: 953 Annotation: Subtype: Link Rect: 421, 606, 424, 615 Destination: 953 Annotation: Subtype: Link Rect: 427, 606, 430, 615 Destination: 953 Annotation: Subtype: Link Rect: 97, 593, 97, 594 Annotation: Subtype: Link Rect: 98, 595, 102, 604 Destination: 953 Annotation: Subtype: Link Rect: 104, 595, 108, 604 Destination: 953 Annotation: Subtype: Link Rect: 110, 595, 114, 604 Destination: 953 Annotation: Subtype: Link Rect: 116, 595, 120, 604 Destination: 953 Annotation: Subtype: Link Rect: 182, 593, 182, 594 Annotation: Subtype: Link Rect: 184, 595, 187, 604 Destination: 953 Annotation: Subtype: Link Rect: 190, 595, 193, 604 Destination: 953 Annotation: Subtype: Link Rect: 196, 595, 199, 604 Destination: 953 Annotation: Subtype: Link Rect: 273, 593, 273, 594 Annotation: Subtype: Link Rect: 275, 595, 278, 604 Destination: 953 Annotation: Subtype: Link Rect: 280, 595, 284, 604 Destination: 953 Annotation: Subtype: Link Rect: 286, 595, 290, 604 Destination: 953 Annotation: Subtype: Link Rect: 292, 595, 296, 604 Destination: 953 Annotation: Subtype: Link Rect: 298, 595, 302, 604 Destination: 953 Annotation: Subtype: Link Rect: 413, 407, 529, 413 Annotation: Subtype: Link Rect: 44, 314, 49, 323 Destination: 247 Annotation: Subtype: Link Rect: 113, 259, 118, 268 Destination: 247 Annotation: Subtype: Link Rect: 240, 204, 244, 213 Destination: 247 Annotation: Subtype: Link Rect: 246, 204, 251, 213 Destination: 247 Annotation: Subtype: Link Rect: 194, 150, 198, 158 Destination: 247 Annotation: Subtype: Link Rect: 523, 270, 528, 279 Destination: null Annotation: Subtype: Link Rect: 523, 248, 528, 257 Destination: 247 Annotation: Subtype: Link Rect: 344, 215, 349, 224 Destination: 247 Annotation: Subtype: Link Rect: 493, 193, 498, 202 Destination: 247 Annotation: Subtype: Link Rect: 423, 79, 499, 87 Annotation: Subtype: Link Rect: 42, 48, 176, 56 Annotation: Subtype: Link Rect: 467, 662, 491, 685 Annotation: Subtype: Link Rect: 389, 19, 494, 25 Annotation: Subtype: Link Rect: 42, 13, 108, 19 Page: Label: 2 Annotations: Annotation: Subtype: Link Rect: 150, 703, 154, 712 Destination: 247 Annotation: Subtype: Link Rect: 161, 703, 170, 712 Destination: 247 Annotation: Subtype: Link Rect: 254, 703, 263, 712 Destination: null Annotation: Subtype: Link Rect: 266, 659, 275, 668 Destination: null Annotation: Subtype: Link Rect: 164, 615, 173, 624 Destination: null Annotation: Subtype: Link Rect: 188, 505, 271, 514 Destination: null Annotation: Subtype: Link Rect: 287, 451, 296, 460 Destination: null Annotation: Subtype: Link Rect: 64, 122, 73, 131 Destination: null Annotation: Subtype: Link Rect: 337, 692, 346, 701 Destination: null Annotation: Subtype: Link Rect: 451, 571, 460, 580 Destination: null Annotation: Subtype: Link Rect: 511, 505, 520, 514 Destination: null Annotation: Subtype: Link Rect: 481, 473, 490, 482 Destination: null Annotation: Subtype: Link Rect: 313, 385, 393, 394 Destination: null Annotation: Subtype: Link Rect: 485, 297, 494, 306 Destination: null Annotation: Subtype: Link Rect: 445, 144, 454, 153 Destination: null Annotation: Subtype: Link Rect: 486, 133, 495, 142 Destination: null Annotation: Subtype: Link Rect: 367, 111, 376, 120 Destination: null Annotation: Subtype: Link Rect: 315, 100, 324, 109 Destination: null Annotation: Subtype: Link Rect: 445, 19, 549, 25 Annotation: Subtype: Link Rect: 486, 13, 552, 19 Page: Label: 3 Annotations: Annotation: Subtype: Link Rect: 189, 121, 269, 130 Destination: null Annotation: Subtype: Link Rect: 481, 132, 532, 141 Destination: null Annotation: Subtype: Link Rect: 293, 121, 319, 130 Destination: null Annotation: Subtype: Link Rect: 428, 633, 431, 640 Destination: null Annotation: Subtype: Link Rect: 435, 615, 438, 622 Destination: null Annotation: Subtype: Link Rect: 425, 606, 427, 613 Destination: null Annotation: Subtype: Link Rect: 432, 570, 434, 577 Destination: null Annotation: Subtype: Link Rect: 432, 561, 434, 568 Destination: null Annotation: Subtype: Link Rect: 425, 552, 427, 559 Destination: null Annotation: Subtype: Link Rect: 222, 504, 224, 511 Destination: null Annotation: Subtype: Link Rect: 323, 504, 326, 511 Destination: null Annotation: Subtype: Link Rect: 428, 504, 431, 511 Destination: null Annotation: Subtype: Link Rect: 524, 504, 526, 511 Destination: null Annotation: Subtype: Link Rect: 222, 495, 224, 502 Destination: null Annotation: Subtype: Link Rect: 323, 495, 326, 502 Destination: null Annotation: Subtype: Link Rect: 428, 495, 431, 502 Destination: null Annotation: Subtype: Link Rect: 524, 495, 526, 502 Destination: null Annotation: Subtype: Link Rect: 428, 486, 431, 493 Destination: null Annotation: Subtype: Link Rect: 524, 486, 526, 493 Destination: null Annotation: Subtype: Link Rect: 222, 477, 224, 484 Destination: null Annotation: Subtype: Link Rect: 428, 477, 431, 484 Destination: null Annotation: Subtype: Link Rect: 524, 477, 526, 484 Destination: null Annotation: Subtype: Link Rect: 432, 415, 434, 422 Destination: null Annotation: Subtype: Link Rect: 432, 406, 434, 413 Destination: null Annotation: Subtype: Link Rect: 434, 397, 436, 404 Destination: null Annotation: Subtype: Link Rect: 432, 349, 434, 355 Destination: null Annotation: Subtype: Link Rect: 425, 340, 427, 347 Destination: null Annotation: Subtype: Link Rect: 449, 291, 452, 298 Destination: null Annotation: Subtype: Link Rect: 428, 282, 431, 289 Destination: null Annotation: Subtype: Link Rect: 420, 273, 422, 280 Destination: null Annotation: Subtype: Link Rect: 389, 19, 494, 25 Annotation: Subtype: Link Rect: 42, 13, 108, 19 Page: Label: 4 Annotations: Annotation: Subtype: Link Rect: 140, 75, 224, 83 Destination: null Annotation: Subtype: Link Rect: 445, 19, 549, 25 Annotation: Subtype: Link Rect: 486, 13, 552, 19 Page: Label: 5 Annotations: Annotation: Subtype: Link Rect: 169, 692, 178, 701 Destination: null Annotation: Subtype: Link Rect: 44, 549, 72, 558 Destination: 27 Annotation: Subtype: Link Rect: 250, 516, 279, 525 Destination: 70 Annotation: Subtype: Link Rect: 42, 505, 68, 514 Destination: 27 Annotation: Subtype: Link Rect: 425, 615, 453, 624 Destination: 70 Annotation: Subtype: Link Rect: 295, 582, 304, 591 Destination: null Annotation: Subtype: Link Rect: 307, 582, 316, 591 Destination: null Annotation: Subtype: Link Rect: 467, 571, 476, 580 Destination: null Annotation: Subtype: Link Rect: 459, 549, 489, 558 Destination: 70 Annotation: Subtype: Link Rect: 500, 549, 528, 558 Destination: 27 Annotation: Subtype: Link Rect: 464, 516, 493, 525 Destination: 70 Annotation: Subtype: Link Rect: 512, 494, 521, 503 Destination: null Annotation: Subtype: Link Rect: 389, 19, 494, 25 Annotation: Subtype: Link Rect: 42, 13, 108, 19 Page: Label: 6 Annotations: Annotation: Subtype: Link Rect: 148, 73, 231, 82 Destination: null Annotation: Subtype: Link Rect: 343, 238, 371, 247 Destination: 81 Annotation: Subtype: Link Rect: 436, 205, 464, 214 Destination: 108 Annotation: Subtype: Link Rect: 370, 161, 452, 170 Destination: null Annotation: Subtype: Link Rect: 469, 161, 552, 170 Destination: null Annotation: Subtype: Link Rect: 313, 150, 333, 159 Destination: null Annotation: Subtype: Link Rect: 356, 51, 463, 60 Destination: null Annotation: Subtype: Link Rect: 445, 19, 549, 25 Annotation: Subtype: Link Rect: 486, 13, 552, 19 Page: Label: 7 Annotations: Annotation: Subtype: Link Rect: 252, 176, 281, 185 Destination: 125 Annotation: Subtype: Link Rect: 42, 165, 64, 174 Destination: 125 Annotation: Subtype: Link Rect: 44, 100, 73, 109 Destination: 168 Annotation: Subtype: Link Rect: 157, 56, 166, 65 Destination: null Annotation: Subtype: Link Rect: 253, 56, 279, 65 Destination: 125 Annotation: Subtype: Link Rect: 295, 144, 322, 153 Destination: 144 Annotation: Subtype: Link Rect: 389, 19, 494, 25 Annotation: Subtype: Link Rect: 42, 13, 108, 19 Page: Label: 8 Annotations: Annotation: Subtype: Link Rect: 64, 332, 90, 341 Destination: 125 Annotation: Subtype: Link Rect: 259, 299, 284, 308 Destination: 125 Annotation: Subtype: Link Rect: 162, 288, 187, 297 Destination: 144 Annotation: Subtype: Link Rect: 228, 222, 284, 231 Destination: 125 Annotation: Subtype: Link Rect: 64, 200, 94, 209 Destination: 168 Annotation: Subtype: Link Rect: 245, 112, 297, 121 Destination: 125 Annotation: Subtype: Link Rect: 343, 321, 396, 330 Destination: 125 Annotation: Subtype: Link Rect: 426, 288, 435, 297 Destination: null Annotation: Subtype: Link Rect: 368, 266, 393, 275 Destination: 125 Annotation: Subtype: Link Rect: 396, 255, 426, 264 Destination: 168 Annotation: Subtype: Link Rect: 515, 134, 543, 143 Destination: 189 Annotation: Subtype: Link Rect: 315, 112, 345, 121 Destination: 168 Annotation: Subtype: Link Rect: 387, 102, 415, 111 Destination: 189 Annotation: Subtype: Link Rect: 341, 91, 369, 100 Destination: 189 Annotation: Subtype: Link Rect: 513, 69, 542, 78 Destination: 189 Annotation: Subtype: Link Rect: 418, 47, 446, 56 Destination: 108 Annotation: Subtype: Link Rect: 445, 19, 549, 25 Annotation: Subtype: Link Rect: 486, 13, 552, 19 Page: Label: 9 Annotations: Annotation: Subtype: Link Rect: 226, 119, 230, 128 Destination: 247 Annotation: Subtype: Link Rect: 498, 130, 502, 139 Destination: null Annotation: Subtype: Link Rect: 400, 119, 404, 128 Destination: 247 Annotation: Subtype: Link Rect: 401, 64, 410, 73 Destination: null Annotation: Subtype: Link Rect: 457, 53, 466, 62 Destination: null Annotation: Subtype: Link Rect: 468, 53, 477, 62 Destination: null Annotation: Subtype: Link Rect: 389, 19, 494, 25 Annotation: Subtype: Link Rect: 42, 13, 108, 19 Page: Label: 10 Annotations: Annotation: Subtype: Link Rect: 118, 128, 128, 137 Destination: null Annotation: Subtype: Link Rect: 153, 107, 162, 115 Destination: null Annotation: Subtype: Link Rect: 490, 183, 499, 192 Destination: null Annotation: Subtype: Link Rect: 315, 117, 426, 126 Destination: null Annotation: Subtype: Link Rect: 445, 19, 549, 25 Annotation: Subtype: Link Rect: 486, 13, 552, 19 Page: Label: 11 Annotations: Annotation: Subtype: Link Rect: 264, 659, 269, 668 Destination: 247 Annotation: Subtype: Link Rect: 140, 615, 145, 624 Destination: 247 Annotation: Subtype: Link Rect: 183, 593, 192, 602 Destination: null Annotation: Subtype: Link Rect: 199, 505, 208, 514 Destination: null Annotation: Subtype: Link Rect: 108, 440, 117, 449 Destination: null Annotation: Subtype: Link Rect: 142, 407, 150, 416 Destination: null Annotation: Subtype: Link Rect: 65, 374, 74, 383 Destination: null Annotation: Subtype: Link Rect: 44, 253, 53, 262 Destination: null Annotation: Subtype: Link Rect: 76, 199, 85, 208 Destination: null Annotation: Subtype: Link Rect: 87, 199, 96, 208 Destination: null Annotation: Subtype: Link Rect: 108, 155, 117, 164 Destination: null Annotation: Subtype: Link Rect: 171, 45, 180, 54 Destination: null Annotation: Subtype: Link Rect: 373, 692, 382, 701 Destination: null Annotation: Subtype: Link Rect: 365, 648, 374, 657 Destination: null Annotation: Subtype: Link Rect: 366, 637, 375, 646 Destination: null Annotation: Subtype: Link Rect: 473, 604, 482, 613 Destination: null Annotation: Subtype: Link Rect: 427, 593, 436, 602 Destination: null Annotation: Subtype: Link Rect: 416, 582, 425, 591 Destination: null Annotation: Subtype: Link Rect: 295, 527, 304, 536 Destination: null Annotation: Subtype: Link Rect: 365, 462, 369, 471 Destination: null Annotation: Subtype: Link Rect: 371, 462, 380, 471 Destination: null Annotation: Subtype: Link Rect: 382, 462, 391, 471 Destination: null Annotation: Subtype: Link Rect: 489, 451, 498, 460 Destination: null Annotation: Subtype: Link Rect: 295, 396, 304, 405 Destination: null Annotation: Subtype: Link Rect: 473, 330, 482, 339 Destination: null Annotation: Subtype: Link Rect: 489, 308, 498, 317 Destination: null Annotation: Subtype: Link Rect: 328, 286, 337, 295 Destination: null Annotation: Subtype: Link Rect: 401, 264, 410, 273 Destination: null Annotation: Subtype: Link Rect: 508, 242, 516, 251 Destination: null Annotation: Subtype: Link Rect: 519, 242, 528, 251 Destination: null Annotation: Subtype: Link Rect: 314, 199, 323, 208 Destination: null Annotation: Subtype: Link Rect: 389, 19, 494, 25 Annotation: Subtype: Link Rect: 42, 13, 108, 19 Page: Label: 12 Annotations: Annotation: Subtype: Link Rect: 64, 593, 73, 602 Destination: null Annotation: Subtype: Link Rect: 229, 188, 301, 195 Annotation: Subtype: Link Rect: 62, 177, 124, 184 Annotation: Subtype: Link Rect: 77, 85, 301, 92 Annotation: Subtype: Link Rect: 77, 74, 199, 81 Annotation: Subtype: Link Rect: 77, 63, 301, 70 Annotation: Subtype: Link Rect: 77, 52, 170, 59 Annotation: Subtype: Link Rect: 176, 52, 187, 59 Annotation: Subtype: Link Rect: 328, 704, 552, 712 Annotation: Subtype: Link Rect: 328, 693, 552, 701 Annotation: Subtype: Link Rect: 328, 682, 453, 690 Annotation: Subtype: Link Rect: 459, 682, 470, 690 Annotation: Subtype: Link Rect: 328, 671, 552, 679 Annotation: Subtype: Link Rect: 328, 660, 552, 668 Annotation: Subtype: Link Rect: 328, 649, 356, 657 Annotation: Subtype: Link Rect: 362, 649, 373, 657 Annotation: Subtype: Link Rect: 328, 638, 552, 646 Annotation: Subtype: Link Rect: 328, 627, 552, 635 Annotation: Subtype: Link Rect: 328, 616, 373, 624 Annotation: Subtype: Link Rect: 328, 605, 552, 613 Annotation: Subtype: Link Rect: 328, 595, 552, 602 Annotation: Subtype: Link Rect: 328, 584, 461, 591 Annotation: Subtype: Link Rect: 328, 573, 552, 580 Annotation: Subtype: Link Rect: 328, 562, 511, 569 Annotation: Subtype: Link Rect: 517, 562, 528, 569 Annotation: Subtype: Link Rect: 328, 551, 552, 558 Annotation: Subtype: Link Rect: 328, 540, 552, 547 Annotation: Subtype: Link Rect: 328, 529, 464, 536 Annotation: Subtype: Link Rect: 470, 529, 485, 536 Annotation: Subtype: Link Rect: 328, 518, 552, 525 Annotation: Subtype: Link Rect: 328, 507, 552, 514 Annotation: Subtype: Link Rect: 328, 496, 552, 503 Annotation: Subtype: Link Rect: 328, 485, 526, 492 Annotation: Subtype: Link Rect: 532, 485, 539, 492 Annotation: Subtype: Link Rect: 328, 474, 552, 482 Annotation: Subtype: Link Rect: 328, 463, 552, 471 Annotation: Subtype: Link Rect: 328, 452, 552, 460 Annotation: Subtype: Link Rect: 328, 441, 386, 449 Annotation: Subtype: Link Rect: 392, 441, 407, 449 Annotation: Subtype: Link Rect: 328, 430, 552, 438 Annotation: Subtype: Link Rect: 328, 419, 552, 427 Annotation: Subtype: Link Rect: 328, 408, 487, 416 Annotation: Subtype: Link Rect: 493, 408, 508, 416 Annotation: Subtype: Link Rect: 328, 397, 552, 405 Annotation: Subtype: Link Rect: 328, 386, 552, 394 Annotation: Subtype: Link Rect: 328, 375, 552, 383 Annotation: Subtype: Link Rect: 328, 364, 339, 372 Annotation: Subtype: Link Rect: 345, 364, 356, 372 Annotation: Subtype: Link Rect: 328, 353, 552, 361 Annotation: Subtype: Link Rect: 328, 342, 552, 350 Annotation: Subtype: Link Rect: 328, 332, 511, 339 Annotation: Subtype: Link Rect: 517, 332, 532, 339 Annotation: Subtype: Link Rect: 328, 321, 552, 328 Annotation: Subtype: Link Rect: 328, 310, 552, 317 Annotation: Subtype: Link Rect: 328, 299, 482, 306 Annotation: Subtype: Link Rect: 488, 299, 495, 306 Annotation: Subtype: Link Rect: 328, 288, 552, 295 Annotation: Subtype: Link Rect: 328, 277, 431, 284 Annotation: Subtype: Link Rect: 437, 277, 448, 284 Annotation: Subtype: Link Rect: 328, 266, 552, 273 Annotation: Subtype: Link Rect: 328, 255, 552, 262 Annotation: Subtype: Link Rect: 328, 244, 443, 251 Annotation: Subtype: Link Rect: 328, 233, 552, 240 Annotation: Subtype: Link Rect: 328, 222, 552, 229 Annotation: Subtype: Link Rect: 328, 211, 546, 218 Annotation: Subtype: Link Rect: 328, 200, 339, 208 Annotation: Subtype: Link Rect: 328, 189, 552, 197 Annotation: Subtype: Link Rect: 328, 178, 552, 186 Annotation: Subtype: Link Rect: 328, 167, 391, 175 Annotation: Subtype: Link Rect: 397, 167, 415, 175 Annotation: Subtype: Link Rect: 421, 167, 432, 175 Annotation: Subtype: Link Rect: 328, 156, 552, 164 Annotation: Subtype: Link Rect: 328, 145, 552, 153 Annotation: Subtype: Link Rect: 328, 134, 356, 142 Annotation: Subtype: Link Rect: 362, 134, 373, 142 Annotation: Subtype: Link Rect: 328, 123, 335, 131 Annotation: Subtype: Link Rect: 339, 123, 552, 131 Annotation: Subtype: Link Rect: 328, 112, 527, 120 Annotation: Subtype: Link Rect: 533, 112, 544, 120 Annotation: Subtype: Link Rect: 328, 101, 385, 109 Annotation: Subtype: Link Rect: 391, 101, 552, 109 Annotation: Subtype: Link Rect: 328, 90, 377, 98 Annotation: Subtype: Link Rect: 328, 79, 552, 87 Annotation: Subtype: Link Rect: 328, 69, 552, 76 Annotation: Subtype: Link Rect: 328, 58, 367, 65 Annotation: Subtype: Link Rect: 373, 58, 390, 65 Annotation: Subtype: Link Rect: 445, 19, 549, 25 Annotation: Subtype: Link Rect: 486, 13, 552, 19 Page: Label: 13 Annotations: Annotation: Subtype: Link Rect: 57, 704, 281, 712 Annotation: Subtype: Link Rect: 57, 693, 281, 701 Annotation: Subtype: Link Rect: 57, 682, 107, 690 Annotation: Subtype: Link Rect: 112, 682, 120, 690 Annotation: Subtype: Link Rect: 57, 671, 281, 679 Annotation: Subtype: Link Rect: 57, 660, 281, 668 Annotation: Subtype: Link Rect: 57, 649, 281, 657 Annotation: Subtype: Link Rect: 57, 638, 193, 646 Annotation: Subtype: Link Rect: 199, 638, 214, 646 Annotation: Subtype: Link Rect: 57, 627, 281, 635 Annotation: Subtype: Link Rect: 57, 616, 281, 624 Annotation: Subtype: Link Rect: 57, 605, 136, 613 Annotation: Subtype: Link Rect: 142, 605, 157, 613 Annotation: Subtype: Link Rect: 57, 595, 281, 602 Annotation: Subtype: Link Rect: 57, 584, 233, 591 Annotation: Subtype: Link Rect: 239, 584, 246, 591 Annotation: Subtype: Link Rect: 57, 573, 281, 580 Annotation: Subtype: Link Rect: 57, 562, 281, 569 Annotation: Subtype: Link Rect: 57, 551, 166, 558 Annotation: Subtype: Link Rect: 171, 551, 183, 558 Annotation: Subtype: Link Rect: 57, 540, 281, 547 Annotation: Subtype: Link Rect: 57, 529, 195, 536 Annotation: Subtype: Link Rect: 201, 529, 216, 536 Annotation: Subtype: Link Rect: 57, 518, 281, 525 Annotation: Subtype: Link Rect: 57, 507, 281, 514 Annotation: Subtype: Link Rect: 57, 496, 156, 503 Annotation: Subtype: Link Rect: 57, 485, 281, 492 Annotation: Subtype: Link Rect: 57, 474, 281, 482 Annotation: Subtype: Link Rect: 57, 463, 159, 471 Annotation: Subtype: Link Rect: 165, 463, 281, 471 Annotation: Subtype: Link Rect: 57, 452, 193, 460 Annotation: Subtype: Link Rect: 198, 452, 217, 460 Annotation: Subtype: Link Rect: 57, 441, 281, 449 Annotation: Subtype: Link Rect: 57, 430, 281, 438 Annotation: Subtype: Link Rect: 57, 419, 93, 427 Annotation: Subtype: Link Rect: 99, 419, 110, 427 Annotation: Subtype: Link Rect: 57, 408, 281, 416 Annotation: Subtype: Link Rect: 57, 397, 281, 405 Annotation: Subtype: Link Rect: 57, 386, 162, 394 Annotation: Subtype: Link Rect: 167, 386, 179, 394 Annotation: Subtype: Link Rect: 57, 375, 281, 383 Annotation: Subtype: Link Rect: 57, 364, 281, 372 Annotation: Subtype: Link Rect: 57, 353, 168, 361 Annotation: Subtype: Link Rect: 173, 353, 181, 361 Annotation: Subtype: Link Rect: 57, 342, 281, 350 Annotation: Subtype: Link Rect: 57, 332, 281, 339 Annotation: Subtype: Link Rect: 57, 321, 244, 328 Annotation: Subtype: Link Rect: 250, 321, 261, 328 Annotation: Subtype: Link Rect: 57, 310, 281, 317 Annotation: Subtype: Link Rect: 57, 299, 281, 306 Annotation: Subtype: Link Rect: 57, 288, 152, 295 Annotation: Subtype: Link Rect: 158, 288, 169, 295 Annotation: Subtype: Link Rect: 57, 277, 281, 284 Annotation: Subtype: Link Rect: 57, 266, 281, 273 Annotation: Subtype: Link Rect: 57, 255, 198, 262 Annotation: Subtype: Link Rect: 203, 255, 211, 262 Annotation: Subtype: Link Rect: 57, 244, 281, 251 Annotation: Subtype: Link Rect: 57, 233, 281, 240 Annotation: Subtype: Link Rect: 57, 222, 173, 229 Annotation: Subtype: Link Rect: 57, 211, 281, 218 Annotation: Subtype: Link Rect: 57, 200, 190, 208 Annotation: Subtype: Link Rect: 196, 200, 275, 208 Annotation: Subtype: Link Rect: 57, 189, 69, 197 Annotation: Subtype: Link Rect: 57, 178, 281, 186 Annotation: Subtype: Link Rect: 57, 167, 254, 175 Annotation: Subtype: Link Rect: 260, 167, 275, 175 Annotation: Subtype: Link Rect: 57, 156, 281, 164 Annotation: Subtype: Link Rect: 57, 145, 281, 153 Annotation: Subtype: Link Rect: 57, 134, 281, 142 Annotation: Subtype: Link Rect: 57, 123, 219, 131 Annotation: Subtype: Link Rect: 224, 123, 236, 131 Annotation: Subtype: Link Rect: 57, 112, 281, 120 Annotation: Subtype: Link Rect: 57, 101, 281, 109 Annotation: Subtype: Link Rect: 57, 90, 198, 98 Annotation: Subtype: Link Rect: 204, 90, 215, 98 Annotation: Subtype: Link Rect: 57, 79, 281, 87 Annotation: Subtype: Link Rect: 57, 69, 281, 76 Annotation: Subtype: Link Rect: 57, 58, 124, 65 Annotation: Subtype: Link Rect: 130, 58, 145, 65 Annotation: Subtype: Link Rect: 308, 704, 532, 712 Annotation: Subtype: Link Rect: 308, 693, 532, 701 Annotation: Subtype: Link Rect: 308, 682, 439, 690 Annotation: Subtype: Link Rect: 444, 682, 452, 690 Annotation: Subtype: Link Rect: 308, 671, 532, 679 Annotation: Subtype: Link Rect: 308, 660, 532, 668 Annotation: Subtype: Link Rect: 308, 649, 459, 657 Annotation: Subtype: Link Rect: 465, 649, 476, 657 Annotation: Subtype: Link Rect: 308, 638, 532, 646 Annotation: Subtype: Link Rect: 308, 627, 532, 635 Annotation: Subtype: Link Rect: 308, 616, 532, 624 Annotation: Subtype: Link Rect: 308, 605, 410, 613 Annotation: Subtype: Link Rect: 415, 605, 427, 613 Annotation: Subtype: Link Rect: 308, 595, 532, 602 Annotation: Subtype: Link Rect: 308, 584, 408, 591 Annotation: Subtype: Link Rect: 414, 584, 429, 591 Annotation: Subtype: Link Rect: 308, 573, 532, 580 Annotation: Subtype: Link Rect: 308, 562, 532, 569 Annotation: Subtype: Link Rect: 308, 551, 487, 558 Annotation: Subtype: Link Rect: 493, 551, 500, 558 Annotation: Subtype: Link Rect: 308, 540, 532, 547 Annotation: Subtype: Link Rect: 308, 529, 532, 536 Annotation: Subtype: Link Rect: 308, 518, 532, 525 Annotation: Subtype: Link Rect: 308, 507, 420, 514 Annotation: Subtype: Link Rect: 426, 507, 445, 514 Annotation: Subtype: Link Rect: 308, 496, 532, 503 Annotation: Subtype: Link Rect: 308, 485, 532, 492 Annotation: Subtype: Link Rect: 308, 474, 469, 482 Annotation: Subtype: Link Rect: 475, 474, 482, 482 Annotation: Subtype: Link Rect: 308, 463, 532, 471 Annotation: Subtype: Link Rect: 308, 452, 532, 460 Annotation: Subtype: Link Rect: 308, 441, 417, 449 Annotation: Subtype: Link Rect: 422, 441, 434, 449 Annotation: Subtype: Link Rect: 308, 430, 532, 438 Annotation: Subtype: Link Rect: 308, 419, 532, 427 Annotation: Subtype: Link Rect: 308, 408, 526, 416 Annotation: Subtype: Link Rect: 308, 397, 323, 405 Annotation: Subtype: Link Rect: 308, 386, 532, 394 Annotation: Subtype: Link Rect: 308, 375, 532, 383 Annotation: Subtype: Link Rect: 308, 364, 391, 372 Annotation: Subtype: Link Rect: 397, 364, 408, 372 Annotation: Subtype: Link Rect: 308, 353, 532, 361 Annotation: Subtype: Link Rect: 308, 342, 526, 350 Annotation: Subtype: Link Rect: 308, 332, 323, 339 Annotation: Subtype: Link Rect: 308, 321, 532, 328 Annotation: Subtype: Link Rect: 308, 310, 532, 317 Annotation: Subtype: Link Rect: 308, 299, 480, 306 Annotation: Subtype: Link Rect: 486, 299, 501, 306 Annotation: Subtype: Link Rect: 308, 288, 532, 295 Annotation: Subtype: Link Rect: 308, 277, 526, 284 Annotation: Subtype: Link Rect: 308, 266, 320, 273 Annotation: Subtype: Link Rect: 308, 255, 532, 262 Annotation: Subtype: Link Rect: 308, 244, 532, 251 Annotation: Subtype: Link Rect: 308, 233, 532, 240 Annotation: Subtype: Link Rect: 308, 222, 462, 229 Annotation: Subtype: Link Rect: 468, 222, 486, 229 Annotation: Subtype: Link Rect: 308, 211, 532, 218 Annotation: Subtype: Link Rect: 308, 200, 532, 208 Annotation: Subtype: Link Rect: 308, 189, 327, 197 Annotation: Subtype: Link Rect: 333, 189, 352, 197 Annotation: Subtype: Link Rect: 308, 178, 532, 186 Annotation: Subtype: Link Rect: 308, 167, 532, 175 Annotation: Subtype: Link Rect: 308, 156, 373, 164 Annotation: Subtype: Link Rect: 379, 156, 390, 164 Annotation: Subtype: Link Rect: 308, 145, 532, 153 Annotation: Subtype: Link Rect: 308, 134, 532, 142 Annotation: Subtype: Link Rect: 308, 123, 532, 131 Annotation: Subtype: Link Rect: 308, 112, 458, 120 Annotation: Subtype: Link Rect: 308, 101, 532, 109 Annotation: Subtype: Link Rect: 308, 90, 532, 98 Annotation: Subtype: Link Rect: 308, 79, 532, 87 Annotation: Subtype: Link Rect: 308, 69, 453, 76 Annotation: Subtype: Link Rect: 459, 69, 466, 76 Annotation: Subtype: Link Rect: 389, 19, 494, 25 Annotation: Subtype: Link Rect: 42, 13, 108, 19 Checksum: cc293047 Type: CRC32 Checksum: f1290d03b7a0bdb76b4b8b24c6c3baad Type: MD5 Checksum: 3171391249a165c40730defe98722f7c0019e5e7 Type: SHA-1