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Title:          Analysis of extracellular vesicle mRNA derived from plasma using the nCounter platform
Subject:        Scientific Reports, https://doi.org/10.1038/s41598-021-83132-0
Author:         Jillian W. P. Bracht 
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     Item: 
      Title: Analysis of extracellular vesicle mRNA derived from plasma using the nCounter platform
      Children: 
       Item: 
        Title: Results
        Children: 
         Item: 
          Title: Optimization of plasma EV enrichment and EV-RNA extraction methodologies. 
         Item: 
          Title: EV-derived mRNA analysis on nCounter and classifier development. 
         Item: 
          Title: Improvement of classifier performance through removal of genomic DNA. 
       Item: 
        Title: Discussion
       Item: 
        Title: Methods
        Children: 
         Item: 
          Title: Patient samples. 
         Item: 
          Title: Extracellular vesicle enrichment. 
         Item: 
          Title: EV characterization by western blot. 
         Item: 
          Title: EV characterization with cryogenic electron microscopy. 
         Item: 
          Title: RNA extraction. 
         Item: 
          Title: Electrophoretic analysis of RNA. 
         Item: 
          Title: DNase treatment. 
         Item: 
          Title: Gene expression analysis using nCounter. 
         Item: 
          Title: Data normalization and analysis. 
         Item: 
          Title: Classifier algorithm development. 
         Item: 
          Title: Gene expression analysis using qRT-PCR. 
       Item: 
        Title: References
       Item: 
        Title: Acknowledgements
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    Author: Jillian W. P. Bracht 
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       Rect: 155, 521, 275, 509
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 351, 491, 443, 479
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 358, 381, 517, 369
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
  Checksum: 97dfdbdb
   Type: CRC32
  Checksum: a976307382c11387eff795d56b2375e4
   Type: MD5
  Checksum: f5fa96d9a04cefd6ad04d7a3064090de5d00c014
   Type: SHA-1