9dc5155ea112e1689b90ccd705b5bb5f nutrients_a2021m6v13a2145.pdf 99c1855d2bfb89875eec0ead4e89df0c12c9b3b8 nutrients_a2021m6v13a2145.pdf a2cc91320bae7633a382e15c0bb9fc42ae9e3947049fe104235b36a18b700732 nutrients_a2021m6v13a2145.pdf Title: Neuropsychological Learning Deficits as Predictors of Treatment Outcome in Patients with Eating Disorders Subject: Eating disorders (EDs) are severe psychiatric illnesses that require individualized treatments. Decision-making deficits have been associated with EDs. Decision-making learning deficits denote a lack of strategies to elaborate better decisions that can have an impact on recovery and response to treatment. This study used the Iowa Gambling Task (IGT) to investigate learning differences related to treatment outcome in EDs, comparing between patients with a good and bad treatment outcome and healthy controls. Likewise, the predictive role of impaired learning performance on therapy outcome was explored. Four hundred twenty-four participants (233 ED patients and 191 healthy controls) participated in this study. Decision making was assessed using the Iowa Gambling Task before any psychological treatment. All patients received psychological therapy, and treatment outcome was evaluated at discharge. Patients with bad outcome did not show progression in the decision-making task as opposed to those with good outcome and the healthy control sample. Additionally, learning performance in the decision-making task was predictive of their future outcome. The severity of learning deficits in decision making may serve as a predictor of the treatment. These results may provide a starting point of how decision-making learning deficits are operating as dispositional and motivational factors on responsiveness to treatment in EDs. Keywords: eating disorders; decision making; learning; treatment outcome Author: Ignacio Lucas, Romina Miranda-Olivos, Giulia Testa, Roser Granero, Isabel Sánchez, Jessica Sánchez-González, Susana Jiménez-Murcia and Fernando Fernández-Aranda Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Wed Jun 23 05:44:06 2021 CEST ModDate: Wed Jun 23 05:47:30 2021 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 12 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 1191298 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- IBTYZX+VnURWPalladioL Type 1 Custom yes yes no 10 0 OXGKWO+URWPalladioL-Ital Type 1 Custom yes yes no 15 0 IKKMUG+URWPalladioL-Bold Type 1 Custom yes yes no 20 0 FKHKXX+URWPalladioL-Roma Type 1 Custom yes yes no 24 0 GIFXFT+VnURWPalladioL-Bold Type 1 Custom yes yes no 28 0 HGMNRX+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 36 0 MCBCCI+SourceSansRoman-Regular Type 1C Custom yes yes no 58 0 MCBCCM+SourceSansRoman.613wght Type 1C Custom yes yes no 62 0 MCBCCO+SourceSansRoman-Bold Type 1C Custom yes yes no 66 0 SOSCBV+CMSY10 Type 1 Builtin yes yes no 84 0 TLQQFO+EURM10 Type 1 Builtin yes yes no 88 0 FIICIA+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 101 0 FIICIB+PalatinoLinotype CID TrueType Identity-H yes yes yes 104 0 FIICIC+PalatinoLinotype TrueType WinAnsi yes yes no 110 0 FIICIE+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 113 0 FIICIA+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 125 0 FIICIC+PalatinoLinotype TrueType WinAnsi yes yes no 128 0 FIICIE+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 131 0 FIICIA+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 141 0 FIICIC+PalatinoLinotype TrueType WinAnsi yes yes no 144 0 FIICIE+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 147 0 URYLRZ+URWPalladioL-BoldItal Type 1 Custom yes yes no 155 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2022-03-08 02:35:55 CET RepresentationInformation: nutrients_a2021m6v13a2145.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2022-03-07 15:48:15 CET Size: 1191298 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 367 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7b69c6ba Item: Title: Materials and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@46daef40 Children: Item: Title: Participants Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@12f41634 Item: Title: Procedure Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@13c27452 Children: Item: Title: Decision-Making Assessment Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@262b2c86 Item: Title: Treatment Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@371a67ec Item: Title: Data Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5ed828d Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@50d0686 Children: Item: Title: Comparison of the IGT Measures between the Groups Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a3d45bd Item: Title: Discriminative Capacity of the IGT-Learning Score Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1e7c7811 Item: Title: Variables Associated with the CBT Outcome Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@77ec78b9 Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1a3869f4 Item: Title: Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@a38d7a3 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@77f99a05 Info: Title: Neuropsychological Learning Deficits as Predictors of Treatment Outcome in Patients with Eating Disorders Author: Ignacio Lucas, Romina Miranda-Olivos, Giulia Testa, Roser Granero, Isabel Sánchez, Jessica Sánchez-González, Susana Jiménez-Murcia and Fernando Fernández-Aranda Subject: Eating disorders (EDs) are severe psychiatric illnesses that require individualized treatments. Decision-making deficits have been associated with EDs. Decision-making learning deficits denote a lack of strategies to elaborate better decisions that can have an impact on recovery and response to treatment. This study used the Iowa Gambling Task (IGT) to investigate learning differences related to treatment outcome in EDs, comparing between patients with a good and bad treatment outcome and healthy controls. Likewise, the predictive role of impaired learning performance on therapy outcome was explored. Four hundred twenty-four participants (233 ED patients and 191 healthy controls) participated in this study. Decision making was assessed using the Iowa Gambling Task before any psychological treatment. All patients received psychological therapy, and treatment outcome was evaluated at discharge. Patients with bad outcome did not show progression in the decision-making task as opposed to those with good outcome and the healthy control sample. Additionally, learning performance in the decision-making task was predictive of their future outcome. The severity of learning deficits in decision making may serve as a predictor of the treatment. These results may provide a starting point of how decision-making learning deficits are operating as dispositional and motivational factors on responsiveness to treatment in EDs. 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