55183f6ea9f7edad5c622e304c8746e5 nutrients_a2021v13an4426.pdf 43b057891e77637ee8d81c9861f342c47a089977 nutrients_a2021v13an4426.pdf f939c1c95a34cddc5381e03dded6cddc24d6547e2c4376abc28331b7ee30751d nutrients_a2021v13an4426.pdf Title: Transdiagnostic Perspective of Impulsivity and Compulsivity in Obesity: From Cognitive Profile to Self-Reported Dimensions in Clinical Samples with and without Diabetes Subject: Impulsive and compulsive behaviors have both been observed in individuals with obesity. The co-occurrence of obesity and type 2 diabetes (T2D) is more strongly associated with impulsivity, although there are no conclusive results yet. A multidimensional assessment of impulsivity and compulsivity was conducted in individuals with obesity in the absence or presence of T2D, compared with healthy, normal-weight individuals, with highly impulsive patients (gambling disorders), and with highly compulsive patients (anorexia nervosa). Decision making and novelty seeking were used to measure impulsivity, and cognitive flexibility and harm avoidance were used for compulsivity. For impulsivity, patients with obesity and T2D showed poorer decision-making ability compared with healthy individuals. For compulsivity, individuals with only obesity presented less cognitive flexibility and high harm avoidance; these dimensions were not associated with obesity with T2D. This study contributes to the knowledge of the mechanisms associated with diabetes and its association with impulsive–compulsive behaviors, confirming the hypothesis that patients with obesity and T2D would be characterized by higher levels of impulsivity. Keywords: impulsivity; compulsivity; decision making; cognitive flexibility; type 2 diabetes; novelty seeking; harm avoidance Author: Giulia Testa, Bernat Mora-Maltas, Lucía Camacho-Barcia, Roser Granero, Ignacio Lucas, Zaida Agüera, Susana Jiménez-Murcia, Rosa Baños, Valerie Bertaina-Anglade, Cristina Botella, Mònica Bulló, Felipe F. Casanueva, Søren Dalsgaard, José-Manuel Fernández-Real, Barbara Franke, Gema Frühbeck, Montserrat Fitó, Carlos Gómez-Martínez, Xavier Pintó, Geert Poelmans, Francisco J. Tinahones, Rafael de la Torre, Jordi Salas-Salvadó, Lluis Serra-Majem, Stephanie Vos, Theresa Wimberley and Fernando Fernández-Aranda Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Mon Dec 20 12:08:01 2021 CET ModDate: Mon Dec 20 12:11:26 2021 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 14 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 2828614 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- DFJPUL+VnURWPalladioL-Bold Type 1 Custom yes yes no 10 0 XXFART+VnURWPalladioL Type 1 Custom yes yes no 15 0 CECCBP+URWPalladioL-Ital Type 1 Custom yes yes no 19 0 XCNPRT+URWPalladioL-Bold Type 1 Custom yes yes no 24 0 OFUKZR+URWPalladioL-Roma Type 1 Custom yes yes no 28 0 HGMNRX+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 36 0 MCBCCI+SourceSansRoman-Regular Type 1C Custom yes yes no 58 0 MCBCCM+SourceSansRoman.613wght Type 1C Custom yes yes no 62 0 MCBCCO+SourceSansRoman-Bold Type 1C Custom yes yes no 66 0 XDGAQI+EURM10 Type 1 Builtin yes yes no 81 0 YVRSZU+CMSY10 Type 1 Builtin yes yes no 91 0 RGSKFW+URWPalladioL-BoldItal Type 1 Custom yes yes no 98 0 CRUZTT+VnURWPalladioL-Italic Type 1 Custom yes yes no 140 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-05-27 03:17:34 CEST RepresentationInformation: nutrients_a2021v13an4426.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-03-31 12:04:36 CEST Size: 2828614 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 328 FreeObjects: 5 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@44c8afef Item: Title: Materials and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7b69c6ba Children: Item: Title: Study Design and Population Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@46daef40 Item: Title: Psychometric Measures Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@12f41634 Item: Title: Neuropsychological Measures Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@13c27452 Item: Title: Procedure Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@262b2c86 Item: Title: Statistical Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@371a67ec Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5ed828d Children: Item: Title: Descriptive for the Sample Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@50d0686 Item: Title: Comparison of Impulsivity and Compulsivity Measures Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a3d45bd Item: Title: Comparison of Psychological State Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1e7c7811 Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@77ec78b9 Item: Title: Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1a3869f4 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@a38d7a3 Info: Title: Transdiagnostic Perspective of Impulsivity and Compulsivity in Obesity: From Cognitive Profile to Self-Reported Dimensions in Clinical Samples with and without Diabetes Author: Giulia Testa, Bernat Mora-Maltas, Lucía Camacho-Barcia, Roser Granero, Ignacio Lucas, Zaida Agüera, Susana Jiménez-Murcia, Rosa Baños, Valerie Bertaina-Anglade, Cristina Botella, Mònica Bulló, Felipe F. Casanueva, Søren Dalsgaard, José-Manuel Fernández-Real, Barbara Franke, Gema Frühbeck, Montserrat Fitó, Carlos Gómez-Martínez, Xavier Pintó, Geert Poelmans, Francisco J. Tinahones, Rafael de la Torre, Jordi Salas-Salvadó, Lluis Serra-Majem, Stephanie Vos, Theresa Wimberley and Fernando Fernández-Aranda Subject: Impulsive and compulsive behaviors have both been observed in individuals with obesity. The co-occurrence of obesity and type 2 diabetes (T2D) is more strongly associated with impulsivity, although there are no conclusive results yet. A multidimensional assessment of impulsivity and compulsivity was conducted in individuals with obesity in the absence or presence of T2D, compared with healthy, normal-weight individuals, with highly impulsive patients (gambling disorders), and with highly compulsive patients (anorexia nervosa). Decision making and novelty seeking were used to measure impulsivity, and cognitive flexibility and harm avoidance were used for compulsivity. For impulsivity, patients with obesity and T2D showed poorer decision-making ability compared with healthy individuals. For compulsivity, individuals with only obesity presented less cognitive flexibility and high harm avoidance; these dimensions were not associated with obesity with T2D. This study contributes to the knowledge of the mechanisms associated with diabetes and its association with impulsive compulsive behaviors, confirming the hypothesis that patients with obesity and T2D would be characterized by higher levels of impulsivity. 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