601549dc46ac9f28a38b56313c4f444a 269688.pdf 4b1922c23319192602590bfa4e56036bc220d13c 269688.pdf 842558ab4242897c966bf2e5be3ffdea34c160dcda50b4544040296883c5ce84 269688.pdf Title: Outcome measures and biomarkers in chronic inflammatory demyelinating polyradiculoneuropathy: from r Subject: Expert Review of Neurotherapeutics, 2021. doi:10.1080/14737175.2021.1944104 Keywords: Chronic inflammatory demyelinating polyradiculoneuropathy; clinical outcome measures; biomarkers; diagnosis; disease activity; disability; impairment; minimal clinically important difference Author: Jeffrey A. Allen Creator: Arbortext Advanced Print Publisher 11.0.3433/W Unicode Producer: PDFlib+PDI 9.0.3p4 (C++/Win32) CreationDate: Wed Aug 11 08:37:22 2021 CEST ModDate: Wed Aug 11 08:37:46 2021 CEST Tagged: no UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 13 Encrypted: no Page size: 634.32 x 833.04 pts Page rot: 0 File size: 2224408 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- EJHGGH+OpenSans-Semibold CID TrueType Identity-H yes yes yes 516 0 EJHGGJ+ArialUnicodeMS CID TrueType Identity-H yes yes yes 517 0 EJHGHA+OpenSans CID TrueType Identity-H yes yes yes 518 0 ZIRDBG+MyriadPro-Regular Type 1C Custom yes yes yes 524 0 PUTFLT+MyriadPro-Semibold Type 1C Custom yes yes yes 525 0 UTWVYT+MyriadPro-SemiCn Type 1C Custom yes yes yes 526 0 HIPCAX+MyriadPro-Black Type 1C Custom yes yes yes 527 0 NDGXPX+MyriadPro-Bold Type 1C Custom yes yes yes 528 0 CADTAC+MyriadPro-It Type 1C Custom yes yes yes 535 0 ERMSTH+MyriadPro-BoldIt Type 1C Custom yes yes yes 536 0 CKOAWW+MyriadPro-SemiboldSemiCn Type 1C Custom yes yes yes 537 0 CUZXDF+ArialUnicodeMS-Identity-H CID TrueType Identity-H yes yes yes 538 0 BDKKFZ+MyriadPro-SemiCnIt Type 1C Custom yes yes yes 540 0 CLHZHE+MyriadPro-BoldSemiCn Type 1C Custom yes yes yes 541 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-05-27 03:15:32 CEST RepresentationInformation: 269688.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-03-31 12:04:42 CEST Size: 2224408 Format: PDF Version: 1.5 Status: Well-Formed and valid SignatureMatches: PDF-hul ID: PDF-HUL-87 InfoMessage: File header gives version as 1.5, but catalog dictionary gives version as 1.4 MIMEtype: application/pdf PDFMetadata: Objects: 622 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Abstract Destination: 1 Item: Title: 1. Introduction Destination: 1 Item: Title: 2. Defining the treatment response: challenges and limitations Destination: 1 Children: Item: Title: 2.1. Illustrative case 1: treatment of anaïve patient Destination: 1 Item: Title: 2.2. Illustrative case 2: treatment optimization Destination: 1 Item: Title: 2.3. Illustrative case 3: treatment withdrawal Destination: 1 Item: Title: 3. CIDP outcome measures: from clinical trials to clinical practice Destination: 1 Item: Title: 4. Disease activity biomarkers: current landscape and future trends Destination: 1 Children: Item: Title: 4.1. Tissue status Destination: 1 Item: Title: 4.2. Effector mechanisms of CIDP Destination: 1 Item: Title: 4.3. Nerve function Destination: 1 Item: Title: 4.4. Drug effect Destination: 1 Item: Title: 4.5. Combined biomarkers Destination: 1 Item: Title: 5. Conclusion Destination: 1 Item: Title: 6. Expert opinion Destination: 1 Item: Title: Acknowledgments Destination: 1 Item: Title: Funding Destination: 1 Item: Title: Declaration of interest Destination: 1 Item: Title: Reviewer disclosures Destination: 1 Item: Title: References Destination: 1 Info: Title: Outcome measures and biomarkers in chronic inflammatory demyelinating polyradiculoneuropathy: from r Author: Jeffrey A. Allen Subject: Expert Review of Neurotherapeutics, 2021. doi:10.1080/14737175.2021.1944104 Keywords: Chronic inflammatory demyelinating polyradiculoneuropathy; clinical outcome measures; biomarkers; diagnosis; disease activity; disability; impairment; minimal clinically important difference Creator: Arbortext Advanced Print Publisher 11.0.3433/W Unicode Producer: PDFlib+PDI 9.0.3p4 (C++/Win32) CreationDate: Wed Aug 11 09:07:22 CEST 2021 ModDate: Wed Aug 11 09:07:46 CEST 2021 ID: 0xc5ebfdcfc1077c8fd46f94d20d9a56ba, 0xc5ebfdcfc1077c8fd46f94d20d9a56ba Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 512 ImageHeight: 346 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode ColorSpace: ICCBased Name: Im10 Image: NisoImageMetadata: FormatName: image/png ImageWidth: 600 ImageHeight: 694 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Name: Im13 Image: NisoImageMetadata: FormatName: image/png ImageWidth: 600 ImageHeight: 694 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode ColorSpace: ICCBased Name: Im14 Image: NisoImageMetadata: FormatName: image/png ImageWidth: 600 ImageHeight: 448 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Name: Im11 Image: NisoImageMetadata: FormatName: image/png ImageWidth: 600 ImageHeight: 448 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode ColorSpace: ICCBased Name: Im12 Image: NisoImageMetadata: FormatName: image/png ImageWidth: 600 ImageHeight: 674 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Name: Im15 Image: NisoImageMetadata: FormatName: image/png ImageWidth: 600 ImageHeight: 674 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode ColorSpace: ICCBased Name: Im16 Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 200 ImageHeight: 261 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Name: Im1 Image: NisoImageMetadata: FormatName: image/png ImageWidth: 600 ImageHeight: 1010 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Name: Im3 Image: NisoImageMetadata: FormatName: image/png ImageWidth: 3150 ImageHeight: 746 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode ColorSpace: ICCBased Name: Im2 Image: NisoImageMetadata: FormatName: image/png ImageWidth: 600 ImageHeight: 641 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Name: Im5 Image: NisoImageMetadata: FormatName: image/png ImageWidth: 600 ImageHeight: 1010 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode ColorSpace: ICCBased Name: Im4 Image: NisoImageMetadata: FormatName: image/png ImageWidth: 600 ImageHeight: 470 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Name: Im7 Image: NisoImageMetadata: FormatName: image/png ImageWidth: 600 ImageHeight: 641 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode ColorSpace: ICCBased Name: Im6 Image: NisoImageMetadata: FormatName: image/png ImageWidth: 512 ImageHeight: 346 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Name: Im9 Image: NisoImageMetadata: FormatName: image/png ImageWidth: 600 ImageHeight: 470 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode ColorSpace: ICCBased Name: Im8 Fonts: Type0: Font: BaseFont: EJHGGH+OpenSans-Semibold Encoding: Identity-H ToUnicode: true Font: BaseFont: EJHGGJ+ArialUnicodeMS Encoding: Identity-H ToUnicode: true Font: BaseFont: EJHGHA+OpenSans Encoding: Identity-H ToUnicode: true Font: BaseFont: CUZXDF+ArialUnicodeMS-Identity-H Encoding: Identity-H ToUnicode: true Type1: Font: BaseFont: NDGXPX+MyriadPro-Bold FontSubset: true FirstChar: 1 LastChar: 52 FontDescriptor: FontName: MyriadPro-Bold Flags: Nonsymbolic, ForceBold FontBBox: -163, -250, 1256, 989 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: CADTAC+MyriadPro-It FontSubset: true FirstChar: 1 LastChar: 18 FontDescriptor: FontName: MyriadPro-It Flags: Nonsymbolic, Italic FontBBox: -185, -250, 1090, 953 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: ERMSTH+MyriadPro-BoldIt FontSubset: true FirstChar: 1 LastChar: 38 FontDescriptor: FontName: MyriadPro-BoldIt Flags: Nonsymbolic, Italic, ForceBold FontBBox: -201, -250, 1225, 987 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: CKOAWW+MyriadPro-SemiboldSemiCn FontSubset: true FirstChar: 1 LastChar: 23 FontDescriptor: FontName: MyriadPro-SemiboldSemiCn Flags: Nonsymbolic FontBBox: -131, -250, 1115, 886 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: ZIRDBG+MyriadPro-Regular FontSubset: true FirstChar: 1 LastChar: 94 FontDescriptor: FontName: MyriadPro-Regular Flags: Nonsymbolic FontBBox: -157, -250, 1126, 952 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: BDKKFZ+MyriadPro-SemiCnIt FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: MyriadPro-SemiCnIt Flags: Nonsymbolic, Italic FontBBox: -151, -250, 1036, 870 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: PUTFLT+MyriadPro-Semibold FontSubset: true FirstChar: 1 LastChar: 23 FontDescriptor: FontName: MyriadPro-Semibold Flags: Nonsymbolic FontBBox: -161, -250, 1198, 972 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: CLHZHE+MyriadPro-BoldSemiCn FontSubset: true FirstChar: 1 LastChar: 19 FontDescriptor: FontName: MyriadPro-BoldSemiCn Flags: Nonsymbolic, ForceBold FontBBox: -133, -250, 1161, 894 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: UTWVYT+MyriadPro-SemiCn FontSubset: true FirstChar: 1 LastChar: 84 FontDescriptor: FontName: MyriadPro-SemiCn Flags: Nonsymbolic FontBBox: -128, -250, 1059, 876 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: HIPCAX+MyriadPro-Black FontSubset: true FirstChar: 1 LastChar: 16 FontDescriptor: FontName: MyriadPro-Black Flags: Nonsymbolic, ForceBold FontBBox: -166, -251, 1313, 1005 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true CIDFontType2: Font: BaseFont: CUZXDF+ArialUnicodeMS CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: ArialUnicodeMS Flags: Nonsymbolic FontBBox: -1011, -330, 2260, 1078 FontFile2: true Font: BaseFont: EJHGGH+OpenSans-Semibold CIDSystemInfo: Registry: Adobe Registry: UCS Supplement: 0 FontDescriptor: FontName: EJHGGH+OpenSans-Semibold Flags: FixedPitch, Nonsymbolic FontBBox: -583, -282, 1261, 1048 FontFile2: true Font: BaseFont: EJHGGJ+ArialUnicodeMS CIDSystemInfo: Registry: Adobe Registry: UCS Supplement: 0 FontDescriptor: FontName: EJHGGJ+ArialUnicodeMS Flags: FixedPitch, Nonsymbolic FontBBox: -1011, -329, 2260, 1078 FontFile2: true Font: BaseFont: EJHGHA+OpenSans CIDSystemInfo: Registry: Adobe Registry: UCS Supplement: 0 FontDescriptor: FontName: EJHGHA+OpenSans Flags: FixedPitch, Nonsymbolic FontBBox: -549, -270, 1204, 1047 FontFile2: true XMP: application/pdf 10.1080/14737175.2021.1944104 en Outcome measures and biomarkers in chronic inflammatory demyelinating polyradiculoneuropathy: from research to clinical practice Jeffrey A. Allen Filip Eftimov Luis Querol Taylor & Francis Expert Review of Neurotherapeutics, 2021. doi:10.1080/14737175.2021.1944104 Chronic inflammatory demyelinating polyradiculoneuropathy clinical outcome measures biomarkers diagnosis disease activity disability impairment minimal clinically important difference Journal Expert Review of Neurotherapeutics © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. 1473-7175 1744-8360 21 7 805 816 10.1080/14737175.2021.1944104 https://doi.org/10.1080/14737175.2021.1944104 VoR 2021-08-11T12:07:22+05:30 Arbortext Advanced Print Publisher 11.0.3433/W Unicode 2021-08-11T12:07:46+05:30 2021-08-11T12:07:46+05:30 Chronic inflammatory demyelinating polyradiculoneuropathy; clinical outcome measures; biomarkers; diagnosis; disease activity; disability; impairment; minimal clinically important difference PDFlib+PDI 9.0.3p4 (C++/Win32) uuid:66fc8325-1357-4298-b32f-f732dc03e6f3 uuid:ffa81da7-820a-4a9d-b39b-b2c35851ccd2 10.1080/14737175.2021.1944104 2021-07-02 True www.tandfonline.com 10.1080/14737175.2021.1944104 2021-07-02 True www.tandfonline.com Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 156, 42, 477, 51 Annotation: Subtype: Link Rect: 283, 688, 436, 696 Annotation: Subtype: Link Rect: 97, 467, 247, 476 Annotation: Subtype: Link Rect: 202, 447, 427, 457 Annotation: Subtype: Link Rect: 106, 305, 124, 314 Annotation: Subtype: Link Rect: 131, 305, 286, 314 Annotation: Subtype: Link Rect: 106, 215, 122, 224 Annotation: Subtype: Link Rect: 131, 219, 230, 228 Annotation: Subtype: Link Rect: 106, 169, 125, 178 Annotation: Subtype: Link Rect: 131, 176, 232, 185 Page: Label: 1 Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 114, 641, 118, 652 Name: 0bf154f6-fd36-4339-8af0-6ade0f7beacf Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 118, 643, 123, 653 Name: 489d7e44-5893-434a-9097-5542193e9695 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 123, 641, 123, 652 Name: e85e43c5-f080-4a19-8c6b-ce698792e3ee Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 123, 641, 123, 652 Name: 6bca3419-fea5-424a-a5f6-ada43e9a491d Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 184, 641, 188, 652 Name: 41cae7ef-2725-4d38-a60b-161e948649eb Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 188, 643, 193, 653 Name: cd1bb8bc-1fa7-43da-b363-935831f6ef0c Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 193, 641, 193, 652 Name: a33bf37a-ad60-4e2a-8465-777b8d12615a Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 267, 641, 270, 652 Name: cccc0af9-9743-4891-a1a4-5a0274c0380a Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 270, 643, 275, 653 Name: eefe721d-a3fb-4d86-a590-73e3d8fb824b Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 275, 641, 275, 652 Name: a37f438c-d53a-4926-9775-28296b58d665 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 174, 310, 179, 320 Name: 5c47064c-10ab-4897-b7e7-dee08d4bee04 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 181, 310, 186, 320 Name: 4e48bcfd-36b9-4946-82ab-c49de9793835 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 252, 274, 266, 284 Name: 6d35335c-44c9-4ab9-8dc5-3e51470ff943 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 222, 214, 227, 224 Name: 69f2d73a-894e-4f76-a25e-375e4fd85ea1 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 269, 166, 274, 176 Name: 7fd4be7c-c1a2-4f8b-a7b2-347bf37bfc1c Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 276, 166, 281, 176 Name: 2e5444b1-2435-49b6-980d-c857d753fd09 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 141, 118, 146, 128 Name: 572c940b-5ba4-4613-a6fb-d5f83e027838 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 95, 82, 100, 92 Name: fccdd96c-7345-47fa-97e8-714df2875244 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 346, 335, 351, 345 Name: e3f19ed2-4696-4db7-b22c-cd23f6431e2a Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 353, 335, 358, 345 Name: d5527926-642b-4f5f-85ad-027a29e9a455 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 540, 239, 545, 249 Name: bfbe90ca-bf03-4b81-a347-4a47ce064da7 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 547, 239, 556, 249 Name: 611e4fee-8e0d-42e2-bac5-c8e85850dcbe Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 446, 191, 471, 201 Name: ad99e21e-b0a8-4155-a6fb-7beb115199a7 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 348, 179, 358, 189 Name: 93238bf7-eff1-48d0-8f56-c613b9ec629a Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 362, 95, 372, 105 Name: 6c836ea6-7713-4cad-b764-5d1f0e1030be Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 459, 744, 561, 751 Name: 278fed64-5afb-4ae8-bbde-a81ed9310556 Flags: Print Annotation: Subtype: Link Rect: 500, 702, 561, 714 Name: f68726b8-0f5d-4832-aa10-2187288a6509 Flags: Print Page: Label: 2 Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 149, 179, 173, 188 Name: 6e397e4b-75c8-4f20-8efa-fd60d99dbe29 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 269, 167, 294, 176 Name: a4cdcaf2-c297-4216-95fc-50bdf4f0408f Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 393, 683, 403, 692 Name: 686650e1-2c02-424f-8ba6-92ac6ec6681f Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 525, 659, 530, 668 Name: 31a976e7-93e6-4d5d-85b8-b68c82220e36 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 396, 575, 406, 584 Name: 75ff539c-922d-4575-a99d-419338845021 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 447, 491, 471, 500 Name: 1a37e81b-297a-4eb6-808f-685da6056914 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 459, 419, 469, 428 Name: e2ac6fbd-c58e-4376-898b-814dbfde09be Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 513, 311, 523, 320 Name: cf4c96ac-e04c-498c-8c85-4c4305da74bb Flags: Print Destination: 1 Page: Label: 3 Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 139, 455, 168, 464 Name: 6637b07d-7a79-4520-ab67-a8906001f94a Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 355, 551, 401, 560 Name: 64ce2d4d-93cb-42e3-b573-c78a366fbe1d Flags: Print Destination: 1 Page: Label: 4 Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 83, 635, 93, 644 Name: e78402e9-aefc-45a8-a08b-927c04ae4c61 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 78, 599, 83, 608 Name: 70c464f8-41b0-41ef-8f3a-ba9853ddb415 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 262, 383, 294, 392 Name: 45cd88c8-559d-46cc-8c19-0aba10f732fd Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 136, 131, 161, 140 Name: 1d753f60-0179-4eb3-9cd3-459ece2f5845 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 170, 131, 201, 140 Name: 7f729021-e3a4-4265-a7ff-87ab140083a3 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 387, 695, 397, 704 Name: 42d753cf-c622-40eb-8a0f-807ea5c34b47 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 389, 599, 399, 608 Name: 33984c4e-5eb1-4134-b636-c5643d057931 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 526, 575, 558, 584 Name: 14d529d8-b303-43dd-80c4-f76b61c64c08 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 313, 563, 323, 572 Name: a38c5650-4960-4bed-9809-9bbf9ecb942d Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 325, 563, 334, 572 Name: c9b69847-411f-40f7-9840-878148668f83 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 336, 563, 346, 572 Name: a867bfa0-e185-43d7-a016-6bd2ec9cfb4d Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 348, 563, 358, 572 Name: 8ba1ad65-60e3-4738-90aa-f705d8f484c5 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 360, 563, 384, 572 Name: 3e21be28-9ebf-418e-a267-68028526acee Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 412, 203, 422, 212 Name: 3f8d2341-903d-41ca-8dd1-cd0ed360260f Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 331, 107, 340, 116 Name: d4ff7341-d425-4463-926c-e0765a9a20d4 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 373, 71, 403, 80 Name: c118c7e6-d33c-422b-aeb1-95b1837582b9 Flags: Print Destination: 1 Page: Label: 5 Sequence: 6 Page: Label: 6 Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 235, 157, 245, 167 Name: c9edd74d-d41d-444a-846b-6b72c96ce94e Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 241, 732, 261, 740 Name: ad16347a-caf1-4166-9d5c-6b6eb044f4d9 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 331, 557, 338, 565 Name: a907583d-52cf-4ba9-b36e-d788e6da2da8 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 341, 548, 348, 556 Name: 58202714-639e-4172-a691-55c52ae93d46 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 341, 539, 348, 547 Name: 8ec53612-d9f0-4ccf-94e5-0b1bf1572ca1 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 350, 530, 357, 538 Name: 88a4bcb1-e3c1-4253-b5e6-1c32bca63207 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 331, 521, 338, 529 Name: 93ca62a9-22ed-4c1a-937e-12d2bb9830ce Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 341, 512, 348, 520 Name: 51a28be5-d7d0-4431-9129-b6d3a24a6c88 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 339, 503, 346, 511 Name: 771d0eb4-be81-4d1b-b640-d4ad0e75f4c5 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 338, 494, 345, 502 Name: 4308ef08-2019-478e-bbe0-caf724680418 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 320, 485, 328, 493 Name: d9696932-5ef5-4635-a470-6ed0a20ea746 Flags: Print Destination: 1 Page: Label: 7 Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 313, 731, 323, 740 Name: f0ca1f8a-b283-4b82-9f25-2b7376a910bf Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 325, 731, 334, 740 Name: d00dc3c5-39fc-4e37-a3a9-b3bcf0161d34 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 473, 647, 478, 656 Name: 5231ae4e-201d-4a2d-83c9-c89b59e06c2f Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 486, 647, 520, 656 Name: 2964ce3c-831b-4075-a325-aa716c2742e1 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 450, 70, 453, 78 Name: 50cb4e19-77bd-4e46-8cfb-9c6336c1553f Flags: Print Destination: 1 Page: Label: 8 Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 249, 695, 258, 704 Name: 5e40be81-e00c-475d-9961-523d7588c7f7 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 139, 671, 149, 680 Name: f41ecda5-e36c-45ee-8d90-961d8b8b933f Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 283, 503, 293, 512 Name: dd526ece-81ec-40d5-9ecd-2e53e06e1084 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 189, 455, 199, 464 Name: eebfcd31-578c-444e-897e-7b07d30bf277 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 284, 287, 294, 296 Name: 16414f3c-d217-44d9-befd-cb4927d5ca0f Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 284, 191, 294, 200 Name: 340a1b07-6ddd-4f14-a541-80230d9ed5e1 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 197, 71, 206, 80 Name: 6ba9b4d2-2068-46b7-bd0b-c5ef2357f1d1 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 349, 665, 358, 674 Name: 1a7126d1-8235-48d7-a05f-d291e2e96cff Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 313, 581, 318, 590 Name: 2d1e8557-c92a-48d2-910c-18b1ff12fe1b Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 320, 581, 330, 590 Name: cb9f073e-5bba-4a5d-ac16-75ad0c12ad74 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 331, 581, 341, 590 Name: 3a6c235a-23f4-4392-b08a-3607d74ee569 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 313, 533, 323, 542 Name: 2a2b1673-4392-4568-b7c6-1808dec81ebe Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 422, 401, 432, 410 Name: ac2c1f56-d7ac-4f58-8606-656603f442a2 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 477, 269, 487, 278 Name: d6771399-2379-4278-bcd2-09b5cc513356 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 313, 131, 323, 140 Name: 5967dbc3-8e3e-4a01-8c8c-985f6692b4cb Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 472, 95, 482, 104 Name: 75929eae-e9a9-4d43-bb37-dcdd53216b39 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 364, 35, 374, 44 Name: 798366df-646b-4c14-8d61-ebd9ae3e0814 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 376, 35, 386, 44 Name: dfb8fc50-2e9a-475d-b9de-be2eadfc4d52 Flags: Print Destination: 1 Page: Label: 9 Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 84, 707, 94, 716 Name: 22649bd8-517e-4020-ac2d-759325bcf537 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 90, 671, 100, 680 Name: 5255cad1-5b36-4fb0-9ca5-f0af9feb2166 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 166, 383, 176, 392 Name: ffdbe6c0-0bc5-49bd-a44a-17c49f08fb40 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 254, 359, 264, 368 Name: b22f1dc2-7da4-4600-98da-0cb1e2a7f1ee Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 84, 275, 94, 284 Name: f3fda531-d16d-41dc-b8df-6f0b74e5e350 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 286, 215, 295, 224 Name: f9f19962-718f-4b56-9b02-fdd50b7b273c Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 164, 191, 174, 200 Name: 94214f54-e8d3-4735-988d-d3d8f4329292 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 286, 167, 296, 176 Name: eef45580-f47e-4b6d-9178-292fb0a27ec7 Flags: Print Destination: 1 Page: Label: 10 Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 50, 287, 151, 296 Name: 3dddcd1b-804f-4629-aed4-e4af3ead25b9 Flags: Print Annotation: Subtype: Link Rect: 535, 315, 551, 323 Name: cbc60cfa-ff1b-4024-8a09-22398e6a2790 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 334, 275, 351, 283 Name: 76123763-a45f-46c2-8f1d-9ddce28d79ff Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 471, 255, 487, 263 Name: 6fc67bde-5081-4db4-904f-d9419b1cf33c Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 420, 165, 437, 173 Name: fca0802e-9d11-4e9b-90d0-914c63c36c31 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 441, 135, 458, 143 Name: 18c03cdd-f85f-4563-be21-ef13865c65d2 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 494, 85, 510, 93 Name: ef09927c-9ca3-441d-a948-cf0b18910ac9 Flags: Print Destination: 1 Page: Label: 11 Sequence: 12 Annotations: Annotation: Subtype: Link Rect: 272, 732, 288, 740 Name: 77c479ca-841f-4a71-9163-9877e0e78a38 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 72, 652, 88, 660 Name: bac5f567-0199-4c06-b2c6-fbc3d94e7b50 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 173, 622, 189, 630 Name: ee0cb874-9335-4024-b965-3f4db088db82 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 148, 582, 164, 590 Name: 1901526d-f25b-49d1-aa13-960b16679c6d Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 151, 552, 167, 560 Name: 0766908b-ac33-42c1-919b-07a203fdec52 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 72, 522, 88, 530 Name: 83ec9824-fda2-4fa7-97c9-832150c38586 Flags: Print Destination: External Annotation: Subtype: Link Rect: 213, 492, 229, 500 Name: 08e64166-0b77-4453-9787-fab87b13d4ff Flags: Print Destination: External Annotation: Subtype: Link Rect: 272, 472, 288, 480 Name: 933a51f4-08b2-413b-83f3-b5f21590cea8 Flags: Print Destination: External Annotation: Subtype: Link Rect: 259, 432, 275, 440 Name: 008ed8f4-861c-4d10-8cd0-8babcb0ec1c3 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 276, 412, 292, 420 Name: 4dea9f89-e5f8-407d-a340-044f38a70567 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 173, 342, 189, 350 Name: 690a0ce9-f44b-4f4a-b91b-056535d1566c Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 72, 302, 88, 310 Name: 4a7f187a-8ac7-4e43-b366-318747a5746b Flags: Print Destination: External Annotation: Subtype: Link Rect: 218, 272, 234, 280 Name: 0b3f7408-78cc-4f56-92e9-4af2abe79673 Flags: Print Destination: External Annotation: Subtype: Link Rect: 282, 232, 298, 240 Name: 65c73ddc-e97e-4319-81b5-4d07e816b18f Flags: Print Destination: External Annotation: Subtype: Link Rect: 72, 182, 88, 190 Name: ef73fcc6-4ff6-424b-9ec0-e19f4cae0d3a Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 72, 142, 88, 150 Name: e5566d64-e4ff-4091-babe-6505628f434e Flags: Print Destination: External Annotation: Subtype: Link Rect: 195, 92, 211, 100 Name: 86b98bf2-5cec-4584-8baa-b229999d144a Flags: Print Destination: External Annotation: Subtype: Link Rect: 104, 52, 120, 60 Name: 26c91633-7a51-4ed6-bc94-3867a039bc34 Flags: Print Destination: External Annotation: Subtype: Link Rect: 393, 692, 409, 700 Name: 56de1b90-0208-4352-a7af-1f36391cb8f2 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 438, 672, 454, 680 Name: af79cd17-7604-44f5-bdd4-4d10b36bdd12 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 432, 642, 448, 650 Name: 3fc9415e-758a-4f48-9587-b79cc78db2e7 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 459, 612, 475, 620 Name: 79595a4e-d96d-4d36-b89e-fb32dbd3eb11 Flags: Print Destination: External Annotation: Subtype: Link Rect: 334, 562, 351, 570 Name: b58b97db-d61f-4cfb-ac80-0cfc54468137 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 496, 532, 512, 540 Name: 959e4ce0-f2c4-4808-8a6c-19f86de2d630 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 459, 502, 475, 510 Name: bfecc260-388f-4354-b25e-71c46bfeb2b5 Flags: Print Destination: External Annotation: Subtype: Link Rect: 533, 472, 549, 480 Name: fc6ec665-e4cf-430d-86b9-65804223b34c Flags: Print Destination: External Annotation: Subtype: Link Rect: 386, 422, 402, 430 Name: 346fd3d8-0264-4ae2-bd35-5f299079f6f4 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 334, 372, 351, 380 Name: 8035b72f-7dff-4ebe-a9d6-c88d726a1ebd Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 478, 342, 494, 350 Name: e6b439fa-4cb1-496f-a515-5da2709bede5 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 407, 302, 423, 310 Name: 32a2c4ff-7e05-4c50-8b94-a87b7c1caf6a Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 360, 262, 377, 270 Name: edd89b63-7560-4cd3-8bd5-9a780fed4801 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 473, 222, 489, 230 Name: d8b2f9a0-ec16-4227-82dc-9f27e399b173 Flags: Print Destination: External Annotation: Subtype: Link Rect: 539, 192, 555, 200 Name: f3d86bde-15fe-4449-93ea-078d27610bf5 Flags: Print Destination: External Annotation: Subtype: Link Rect: 460, 142, 476, 150 Name: 0b08034a-c722-4e5e-92d4-f141cce8f1c9 Flags: Print Destination: External Annotation: Subtype: Link Rect: 422, 82, 439, 90 Name: de293837-3c7e-48db-81f3-f62b76d833dd Flags: Print Destination: 1 Page: Label: 12 Sequence: 13 Annotations: Annotation: Subtype: Link Rect: 123, 722, 140, 730 Name: fc7964cb-70e3-4198-803b-495c4d7003e1 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 178, 682, 194, 690 Name: d5a60f50-1b52-49ce-86eb-2cb372c24a12 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 104, 642, 120, 650 Name: c668158a-bc83-4cfc-a406-42597831665c Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 193, 592, 209, 600 Name: 9c6fac93-1d9a-40ae-9bb7-6240a3517061 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 258, 572, 274, 580 Name: 46c113bb-401c-40f3-b000-00a2bc3ea5cc Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 203, 562, 299, 570 Name: faf0d9ee-46d3-4193-8a07-4b6cfefa4599 Flags: Print Annotation: Subtype: Link Rect: 72, 552, 128, 560 Name: da1835c8-5b1c-432d-ba94-e58993bb5c78 Flags: Print Annotation: Subtype: Link Rect: 109, 522, 125, 530 Name: 88a4c3fb-9d0d-49d5-9d19-19b2b57ea43d Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 273, 502, 289, 510 Name: 2b71b30f-e841-472b-801c-497715066c51 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 117, 422, 134, 430 Name: 3fee66e8-dc30-4415-b949-5cc2b4ed9ccc Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 273, 422, 298, 430 Name: 7e36c26a-cbd6-43a6-8426-4ab51e09555b Flags: Print Annotation: Subtype: Link Rect: 72, 412, 214, 420 Name: d838e0db-5d71-4fb4-902f-e4f4012935cf Flags: Print Annotation: Subtype: Link Rect: 280, 402, 297, 410 Name: 00a93fc9-8981-4688-a147-107d81d62be8 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 206, 392, 298, 400 Name: 15649233-ec19-4e8b-8c5a-49dc282721a2 Flags: Print Annotation: Subtype: Link Rect: 72, 382, 289, 390 Name: de107256-0739-4aee-8867-5be169d67ec6 Flags: Print Annotation: Subtype: Link Rect: 72, 342, 88, 350 Name: 54fde59e-01bf-4678-9ed3-05e4e934fee8 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 96, 302, 112, 310 Name: ee776cc1-b8df-43a0-933e-328c62015ecf Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 144, 272, 161, 280 Name: aada0950-70dc-4700-b7dd-355242893f55 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 272, 242, 288, 250 Name: fe5e3eaa-c43b-45df-8199-dce307ae774f Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 202, 202, 219, 210 Name: 9bb9df5e-e5da-4069-a5a2-4096aa2b0b43 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 98, 172, 115, 180 Name: 95135541-dca5-42d7-a087-0157885d6bbb Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 282, 142, 298, 150 Name: 8e6fe0ff-6025-4f3f-b5a3-7e37d9259cba Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 159, 102, 176, 110 Name: 6d21286c-6546-404e-b964-95210fd2974c Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 390, 701, 406, 709 Name: 2f1b9ca1-4f31-4d9c-86e2-7028c5e054ee Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 380, 671, 397, 679 Name: aedb0e95-d638-4059-912d-2a7d6631c0ab Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 517, 641, 534, 649 Name: bcd53ba3-2bd6-4c68-a6f0-50b720877a9c Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 530, 571, 546, 579 Name: bc29e407-fda9-4cc0-8f45-1c0761574d9a Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 535, 541, 551, 549 Name: 483b2f2f-c935-4f41-ab79-d3facc689a66 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 534, 511, 551, 519 Name: 4f84109c-cbc8-4266-8cbd-9a1f4be5ce7f Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 535, 471, 551, 479 Name: df6394de-d222-4ef0-8066-a9be4ad1e60e Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 410, 421, 427, 429 Name: 83de370f-f6be-4e06-9ca6-dfc52e731ace Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 535, 391, 551, 399 Name: d9a300ff-3098-4436-8792-a833bb7ff97c Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 531, 351, 547, 359 Name: 2cd5ce57-b7b9-4f31-988d-36da55c9a54a Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 383, 301, 400, 309 Name: 0aea5d1c-e714-4041-a7c5-8a6a110758cf Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 334, 261, 351, 269 Name: bc08c201-1c69-4809-9a5a-0be7dbf02d6a Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 422, 221, 438, 229 Name: eabb2005-3b65-4c58-96c2-d97f230b37db Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 420, 181, 437, 189 Name: adab7cc3-f1f8-4aed-bddc-0a5f3d30ddee Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 535, 151, 551, 159 Name: 9b83fa16-b2d5-41b5-8679-93cce9c86d60 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 400, 111, 417, 119 Name: f93a0358-7867-4866-9ca7-63b8171abdb1 Flags: Print Destination: 1 Checksum: c0dbe7d9 Type: CRC32 Checksum: 601549dc46ac9f28a38b56313c4f444a Type: MD5 Checksum: 4b1922c23319192602590bfa4e56036bc220d13c Type: SHA-1