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Introduction Destination: 1 Item: Title: 2. COVID-19 in PLWH Destination: 1 Children: Item: Title: 2.1. Prevalence, risk factors, and disease severity Destination: 1 Item: Title: 2.2. Demographics and clinical characteristics Destination: 1 Item: Title: 2.3. Viro-immunological features, biomarkers and imaging Destination: 1 Item: Title: 2.4. Outcome Destination: 1 Item: Title: 3. The potential role of antiretroviral therapy (cART) in preventing COVID-19 Destination: 1 Item: Title: 4. Pharmacological management of COVID-19 Destination: 1 Children: Item: Title: 4.1. Antiviral agents Destination: 1 Children: Item: Title: 4.1.1. Antiretroviral drugs Destination: 1 Item: Title: 4.1.2. Type Iand III interferons Destination: 1 Item: Title: 4.1.3. Remdesivir Destination: 1 Item: Title: 4.1.4. Mixed action mechanism drugs (chloroquine, hydroxychloroquine, and azithromycin) Destination: 1 Item: Title: 4.2. Immunomodulatory agents Destination: 1 Children: Item: Title: 4.2.1. 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doi:10.1080/14656566.2021.1887140 COVID-19 SARS-CoV-2 cART remdesivir dexamethasone interferon IL-6 antagonists LPV/r DRV TDF FTC Journal Expert Opinion on Pharmacotherapy © 2021 The Author(s). 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