0dc2af27efe9ec210c1945b51943bb8c 269722.pdf 087fd805aef5e0f0ef98c54cdf3a0ac05ed6db6b 269722.pdf 95fdd3508ac481ef2d1bfdb8b4f5fa0ebdb6b4968dc5bad75443fd1428e5902e 269722.pdf Title: A Real-World Study of the Association between a Brief Group Psychoeducation and the Course of Bipolar Disorder Subject: Although pharmacotherapy is considered the first-line treatment for bipolar disorders (BD), adjunctive psychoeducation has proven its effectiveness in improving self-management of the disease and reducing relapse rates. Few studies have evaluated the effect of brief group psychoeducation on pragmatic variables, such as the number of hospitalizations. The aim of the present study was to assess the mid-term effect of a four-session group psychoeducation on course-related variables in BD. Thirty-two individuals with BD were included in the study. Sixteen were exposed to psychoeducation and were matched to sixteen nonexposed individuals who received their usual treatment. Both groups were compared on insight, treatment adherence, change in the number of hospitalizations and visits to the emergency services, occurrence rate after intervention, and time to the first psychiatric hospitalization and the first urgent attendance. There was a significant reduction in the mean number of hospitalizations and urgent attendances in the exposed group in comparison to the nonexposed group. The first urgent attendance was significantly sooner in the nonexposed cohort. There were no differences between groups in any of the other variables. This intervention has shown benefits for pragmatic variables of the disease course and may be a feasible and cost-effective intervention to routinely implement in the management of BD. Keywords: bipolar disorder; group psychoeducation; disease progression; recurrence; treatment adherence; insight Author: Elisabet Casellas, Beatriz Raventós, Marina Piñeiro-Ríos, Helena Navarro-Martínez, Maite Castillón-Espezel, Maria J. Portella and Ana Martín-Blanco Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Mon May 10 10:32:42 2021 CEST ModDate: Mon May 10 10:36:04 2021 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 10 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 1035551 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- MYTFKK+VnURWPalladioL Type 1 Custom yes yes no 10 0 JZFSPP+URWPalladioL-Ital Type 1 Custom yes yes no 15 0 PDJYOM+URWPalladioL-Bold Type 1 Custom yes yes no 20 0 OANQOU+URWPalladioL-Roma Type 1 Custom yes yes no 24 0 YWWVQQ+VnURWPalladioL-Bold Type 1 Custom yes yes no 28 0 LWQXII+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 36 0 IRWHZX+TimesNewRomanPSMT Type 1C WinAnsi yes yes no 39 0 MCBCCI+SourceSansRoman-Regular Type 1C Custom yes yes no 61 0 MCBCCM+SourceSansRoman.613wght Type 1C Custom yes yes no 65 0 MCBCCO+SourceSansRoman-Bold Type 1C Custom yes yes no 69 0 PDTLUH+CMSY10 Type 1 Builtin yes yes no 81 0 WBVKDJ+URWPalladioL-BoldItal Type 1 Custom yes yes no 91 0 ABCDEE+Palatino Linotype TrueType WinAnsi yes yes no 103 0 ABCDEE+Palatino Linotype,Italic TrueType WinAnsi yes yes no 107 0 ABCDEE+Palatino Linotype,Bold TrueType WinAnsi yes yes no 111 0 ABCDEE+Palatino Linotype CID TrueType Identity-H yes yes yes 115 0 ABCDEE+Palatino Linotype TrueType WinAnsi yes yes no 131 0 ABCDEE+Palatino Linotype,Italic TrueType WinAnsi yes yes no 135 0 ABCDEE+Palatino Linotype,Bold TrueType WinAnsi yes yes no 139 0 ABCDEE+Palatino Linotype CID TrueType Identity-H yes yes yes 143 0 SYVAVM+VnURWPalladioL-Italic Type 1 Custom yes yes no 160 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-05-27 03:14:37 CEST RepresentationInformation: 269722.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-03-31 12:04:44 CEST Size: 1035551 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 292 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@44c8afef Item: Title: Materials and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7b69c6ba Children: Item: Title: Patients and Study Design Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@46daef40 Item: Title: Statistical Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@12f41634 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@13c27452 Children: Item: Title: Demographic and Clinical Characteristics of the Sample Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@262b2c86 Item: Title: Study of the Association between the Intervention and Insight and Treatment Adherence Improvement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@371a67ec Item: Title: Study of the Association between the Intervention and the Number of Hospitalizations and Visits to Emergency Services Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5ed828d Item: Title: Study of the Association between the Intervention and the Rates of Hospitalizations and Visits to Emergency Services Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@50d0686 Item: Title: Study of the Association between the Intervention and the Lapsed Time until the First Hospitalization and the First Visit to the Emergency Services Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a3d45bd Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1e7c7811 Item: Title: Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@77ec78b9 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1a3869f4 Info: Title: A Real-World Study of the Association between a Brief Group Psychoeducation and the Course of Bipolar Disorder Author: Elisabet Casellas, Beatriz Raventós, Marina Piñeiro-Ríos, Helena Navarro-Martínez, Maite Castillón-Espezel, Maria J. Portella and Ana Martín-Blanco Subject: Although pharmacotherapy is considered the first-line treatment for bipolar disorders (BD), adjunctive psychoeducation has proven its effectiveness in improving self-management of the disease and reducing relapse rates. Few studies have evaluated the effect of brief group psychoeducation on pragmatic variables, such as the number of hospitalizations. The aim of the present study was to assess the mid-term effect of a four-session group psychoeducation on course-related variables in BD. Thirty-two individuals with BD were included in the study. Sixteen were exposed to psychoeducation and were matched to sixteen nonexposed individuals who received their usual treatment. Both groups were compared on insight, treatment adherence, change in the number of hospitalizations and visits to the emergency services, occurrence rate after intervention, and time to the first psychiatric hospitalization and the first urgent attendance. There was a significant reduction in the mean number of hospitalizations and urgent attendances in the exposed group in comparison to the nonexposed group. The first urgent attendance was significantly sooner in the nonexposed cohort. There were no differences between groups in any of the other variables. This intervention has shown benefits for pragmatic variables of the disease course and may be a feasible and cost-effective intervention to routinely implement in the management of BD. Keywords: bipolar disorder; group psychoeducation; disease progression; recurrence; treatment adherence; insight Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Mon May 10 10:32:42 CEST 2021 ModDate: Mon May 10 10:36:04 CEST 2021 ID: 0x9ef20ebc401bb5aef72a368828b514f3, 0x9ef20ebc401bb5aef72a368828b514f3 Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: SYVAVM+VnURWPalladioL-Italic FontSubset: true FirstChar: 226 LastChar: 226 FontDescriptor: FontName: SYVAVM+VnURWPalladioL-Italic Flags: Symbolic FontBBox: -170, -305, 1010, 941 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: PDTLUH+CMSY10 FontSubset: true FirstChar: 21 LastChar: 21 FontDescriptor: FontName: PDTLUH+CMSY10 Flags: Symbolic FontBBox: -29, -960, 1116, 775 FontFile: true Font: BaseFont: PDJYOM+URWPalladioL-Bold FontSubset: true FirstChar: 2 LastChar: 241 FontDescriptor: FontName: PDJYOM+URWPalladioL-Bold Flags: Symbolic FontBBox: -152, -301, 1000, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: OANQOU+URWPalladioL-Roma FontSubset: true FirstChar: 2 LastChar: 246 FontDescriptor: FontName: OANQOU+URWPalladioL-Roma Flags: Symbolic FontBBox: -166, -283, 1021, 943 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: MYTFKK+VnURWPalladioL FontSubset: true FirstChar: 160 LastChar: 243 FontDescriptor: FontName: MYTFKK+VnURWPalladioL Flags: Symbolic FontBBox: -166, -283, 1021, 943 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: WBVKDJ+URWPalladioL-BoldItal FontSubset: true FirstChar: 112 LastChar: 112 FontDescriptor: FontName: WBVKDJ+URWPalladioL-BoldItal Flags: Symbolic FontBBox: -170, -300, 1073, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: YWWVQQ+VnURWPalladioL-Bold FontSubset: true FirstChar: 189 LastChar: 226 FontDescriptor: FontName: YWWVQQ+VnURWPalladioL-Bold Flags: Symbolic FontBBox: -152, -301, 1000, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: JZFSPP+URWPalladioL-Ital FontSubset: true FirstChar: 46 LastChar: 122 FontDescriptor: FontName: JZFSPP+URWPalladioL-Ital Flags: Symbolic FontBBox: -170, -305, 1010, 941 FontFile: true EncodingDictionary: Differences: true Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 35, 759, 181, 795 Annotation: Subtype: Link Rect: 515, 759, 560, 795 Annotation: Subtype: Link Rect: 242, 647, 253, 661 Annotation: Subtype: Link Rect: 381, 647, 392, 661 Annotation: Subtype: Link Rect: 55, 346, 154, 355 Annotation: Subtype: Link Rect: 35, 334, 82, 343 Annotation: Subtype: Link Rect: 35, 162, 97, 184 Annotation: Subtype: Link Rect: 153, 89, 154, 98 Annotation: Subtype: Link Rect: 35, 77, 147, 86 Annotation: Subtype: Link Rect: 404, 193, 411, 202 ActionDest: 154 Annotation: Subtype: Link Rect: 411, 193, 418, 202 ActionDest: 154 Annotation: Subtype: Link Rect: 205, 180, 212, 189 ActionDest: 154 Annotation: Subtype: Link Rect: 212, 181, 219, 189 ActionDest: 154 Annotation: Subtype: Link Rect: 477, 180, 484, 189 ActionDest: 154 Annotation: Subtype: Link Rect: 403, 168, 410, 177 ActionDest: 157 Annotation: Subtype: Link Rect: 369, 155, 376, 164 ActionDest: 157 Annotation: Subtype: Link Rect: 534, 130, 541, 139 ActionDest: 157 Annotation: Subtype: Link Rect: 544, 130, 556, 139 ActionDest: 157 Annotation: Subtype: Link Rect: 426, 118, 438, 127 ActionDest: 157 Annotation: Subtype: Link Rect: 439, 118, 451, 127 ActionDest: 157 Annotation: Subtype: Link Rect: 201, 17, 346, 28 Annotation: Subtype: Link Rect: 414, 17, 558, 28 Annotation: Subtype: Link Rect: 35, 458, 87, 477 Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 317, 737, 329, 746 ActionDest: 157 Annotation: Subtype: Link Rect: 477, 737, 489, 746 ActionDest: 157 Annotation: Subtype: Link Rect: 230, 724, 242, 733 ActionDest: 157 Annotation: Subtype: Link Rect: 532, 686, 544, 695 ActionDest: 157 Annotation: Subtype: Link Rect: 544, 686, 556, 695 ActionDest: 157 Annotation: Subtype: Link Rect: 245, 674, 257, 683 ActionDest: 157 Annotation: Subtype: Link Rect: 257, 674, 269, 683 ActionDest: 157 Annotation: Subtype: Link Rect: 247, 661, 259, 670 ActionDest: 157 Annotation: Subtype: Link Rect: 259, 661, 271, 670 ActionDest: 157 Annotation: Subtype: Link Rect: 402, 661, 414, 670 ActionDest: 157 Annotation: Subtype: Link Rect: 543, 661, 555, 670 ActionDest: 157 Annotation: Subtype: Link Rect: 227, 649, 239, 658 ActionDest: 157 Annotation: Subtype: Link Rect: 240, 649, 251, 658 ActionDest: 157 Annotation: Subtype: Link Rect: 323, 649, 335, 658 ActionDest: 157 Annotation: Subtype: Link Rect: 458, 649, 470, 658 ActionDest: 157 Annotation: Subtype: Link Rect: 470, 649, 482, 658 ActionDest: 157 Annotation: Subtype: Link Rect: 217, 636, 229, 645 ActionDest: 157 Annotation: Subtype: Link Rect: 380, 636, 392, 645 ActionDest: 157 Annotation: Subtype: Link Rect: 392, 636, 404, 645 ActionDest: 157 Annotation: Subtype: Link Rect: 337, 586, 349, 595 ActionDest: 157 Annotation: Subtype: Link Rect: 204, 321, 216, 330 ActionDest: 157 Annotation: Subtype: Link Rect: 467, 321, 479, 330 ActionDest: 157 Annotation: Subtype: Link Rect: 480, 321, 492, 330 ActionDest: 157 Page: Sequence: 3 Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 278, 647, 290, 656 ActionDest: 157 Annotation: Subtype: Link Rect: 214, 442, 221, 454 ActionDest: 88 Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 280, 633, 287, 645 ActionDest: 95 Annotation: Subtype: Link Rect: 198, 570, 205, 582 ActionDest: 95 Annotation: Subtype: Link Rect: 191, 348, 198, 358 ActionDest: 123 Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 302, 523, 309, 535 ActionDest: 123 Annotation: Subtype: Link Rect: 375, 123, 387, 132 ActionDest: 157 Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 227, 597, 239, 606 ActionDest: 157 Annotation: Subtype: Link Rect: 240, 597, 252, 606 ActionDest: 157 Annotation: Subtype: Link Rect: 344, 572, 356, 581 ActionDest: 157 Annotation: Subtype: Link Rect: 415, 433, 427, 443 ActionDest: 164 Annotation: Subtype: Link Rect: 509, 421, 521, 430 ActionDest: 164 Annotation: Subtype: Link Rect: 307, 383, 319, 392 ActionDest: 157 Annotation: Subtype: Link Rect: 280, 371, 292, 380 ActionDest: 157 Annotation: Subtype: Link Rect: 293, 371, 305, 380 ActionDest: 164 Annotation: Subtype: Link Rect: 426, 333, 438, 342 ActionDest: 164 Annotation: Subtype: Link Rect: 439, 333, 450, 342 ActionDest: 164 Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 424, 545, 560, 556 Annotation: Subtype: Link Rect: 166, 533, 277, 544 Annotation: Subtype: Link Rect: 147, 185, 185, 196 Annotation: Subtype: Link Rect: 191, 185, 227, 196 Annotation: Subtype: Link Rect: 378, 162, 415, 173 Annotation: Subtype: Link Rect: 318, 139, 355, 150 Annotation: Subtype: Link Rect: 453, 116, 491, 127 Annotation: Subtype: Link Rect: 59, 70, 97, 81 Page: Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 165, 710, 203, 720 Annotation: Subtype: Link Rect: 209, 710, 245, 720 Annotation: Subtype: Link Rect: 372, 675, 410, 686 Annotation: Subtype: Link Rect: 416, 675, 452, 686 Annotation: Subtype: Link Rect: 520, 652, 557, 663 Annotation: Subtype: Link Rect: 59, 641, 95, 651 Annotation: Subtype: Link Rect: 391, 617, 429, 628 Annotation: Subtype: Link Rect: 435, 617, 471, 628 Annotation: Subtype: Link Rect: 519, 594, 557, 605 Annotation: Subtype: Link Rect: 257, 571, 295, 582 Annotation: Subtype: Link Rect: 519, 548, 557, 559 Annotation: Subtype: Link Rect: 154, 514, 192, 525 Annotation: Subtype: Link Rect: 95, 480, 133, 490 Annotation: Subtype: Link Rect: 139, 480, 175, 490 Annotation: Subtype: Link Rect: 324, 445, 362, 456 Annotation: Subtype: Link Rect: 368, 445, 404, 456 Annotation: Subtype: Link Rect: 520, 422, 557, 433 Annotation: Subtype: Link Rect: 59, 411, 95, 421 Annotation: Subtype: Link Rect: 86, 354, 124, 364 Annotation: Subtype: Link Rect: 512, 307, 550, 318 Annotation: Subtype: Link Rect: 210, 284, 248, 295 Annotation: Subtype: Link Rect: 136, 250, 173, 260 Annotation: Subtype: Link Rect: 259, 192, 297, 203 Annotation: Subtype: Link Rect: 303, 192, 339, 203 Annotation: Subtype: Link Rect: 309, 146, 346, 157 Annotation: Subtype: Link Rect: 59, 123, 97, 134 Annotation: Subtype: Link Rect: 399, 100, 437, 111 Annotation: Subtype: Link Rect: 443, 100, 479, 111 Annotation: Subtype: Link Rect: 331, 65, 368, 76 Annotation: Subtype: Link Rect: 374, 65, 411, 76 Page: Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 113, 722, 149, 732 Annotation: Subtype: Link Rect: 323, 686, 360, 697 Annotation: Subtype: Link Rect: 285, 663, 322, 674 Annotation: Subtype: Link Rect: 104, 630, 142, 640 Annotation: Subtype: Link Rect: 148, 630, 184, 640 Annotation: Subtype: Link Rect: 519, 606, 557, 617 Annotation: Subtype: Link Rect: 59, 595, 95, 605 Checksum: 4300f1ab Type: CRC32 Checksum: 0dc2af27efe9ec210c1945b51943bb8c Type: MD5 Checksum: 087fd805aef5e0f0ef98c54cdf3a0ac05ed6db6b Type: SHA-1