d70942e300a91c4c893b5282a24d79f2 270201.pdf 70a7832fa1567a7f56e53f34fc341c974384995a 270201.pdf 62aa76dc54dbd6f8f9611d2bd8504f5c8b2e672ec93be978f2d66b5cd2e8b64d 270201.pdf Title: Long‐term efficacy and safety of risankizumab for the treatment of moderate‐to‐severe plaque psoriasis: interim analysis of the LIMMitless open‐label extension trial beyond 3 years of follow‐up Subject: Br J Dermatol 2021.185:1135-1145 Creator: Arbortext Advanced Print Publisher 9.1.531/W Unicode Producer: Acrobat Distiller 10.1.16 (Windows); modified using iText 4.2.0 by 1T3XT CreationDate: Tue Nov 30 08:49:22 2021 CET ModDate: Mon Jan 30 09:20:50 2023 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 11 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 1581709 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- DEHHOD+AdvTTec369687+22 Type 1C Custom yes yes yes 61 0 DEHHOA+AdvPSJOANNA-I Type 1C MacRoman yes yes no 46 0 DEHHPE+AdvP4C4E74 Type 1C Custom yes yes no 62 0 DEHHOB+AdvPSJOANNA-B Type 1C WinAnsi yes yes no 47 0 DEHHOC+AdvPSJOANNA Type 1C Custom yes yes no 48 0 DEHHPF+AdvTTec369687 Type 1C WinAnsi yes yes no 51 0 DEHHIM+AdvMETAN-C Type 1C WinAnsi yes yes no 162 0 DEHHIN+AdvNBSC85 Type 1C WinAnsi yes yes no 163 0 DEHHJO+AdvMetaLF-M Type 1C WinAnsi yes yes no 164 0 DEHHJP+AdvMETAB-R Type 1C MacRoman yes yes no 50 0 DEHHKA+AdvMETAN-R Type 1C MacRoman yes yes no 52 0 DEHHMA+MyriadPro-Semibold Type 1C WinAnsi yes yes no 165 0 Times-Roman Type 1 WinAnsi no no no 5 0 DEHIAH+AdvTTec369687+20 Type 1C WinAnsi yes yes no 49 0 DEHIAG+AdvTT3713a231+20 Type 1C WinAnsi yes yes no 53 0 DEHICH+AdvPSSym Type 1C Custom yes yes no 63 0 DEHIPD+AdvPSJOANNA-SB Type 1C WinAnsi yes yes no 73 0 DEHLBG+Helvetica-Bold Type 1C WinAnsi yes yes no 84 0 DEIEJI+AdvTTc6ee16d2.I Type 1C WinAnsi yes yes no 126 0 DEIEKJ+AdvSPSASORT Type 1C Custom yes yes no 133 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-05-27 03:11:43 CEST RepresentationInformation: 270201.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-03-31 12:04:50 CEST Size: 1581709 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 0 FreeObjects: 2 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseThumbs Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 228 ImageHeight: 45 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 228 ImageHeight: 45 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1857 ImageHeight: 1045 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1803 ImageHeight: 2378 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1881 ImageHeight: 1114 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1752 ImageHeight: 2023 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1795 ImageHeight: 859 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1881 ImageHeight: 915 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type1: Font: BaseFont: DEHHIM+AdvMETAN-C FontSubset: true FirstChar: 65 LastChar: 84 FontDescriptor: FontName: DEHHIM+AdvMETAN-C Flags: Nonsymbolic FontBBox: -93, -187, 1166, 781 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DEHHIN+AdvNBSC85 FontSubset: true FirstChar: 66 LastChar: 74 FontDescriptor: FontName: DEHHIN+AdvNBSC85 Flags: Nonsymbolic FontBBox: -197, -281, 1197, 781 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DEHHJO+AdvMetaLF-M FontSubset: true FirstChar: 66 LastChar: 121 FontDescriptor: FontName: DEHHJO+AdvMetaLF-M Flags: Serif, Nonsymbolic FontBBox: -156, -208, 1177, 916 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DEHHMA+MyriadPro-Semibold FontSubset: true FirstChar: 68 LastChar: 105 FontDescriptor: FontName: DEHHMA+MyriadPro-Semibold Flags: Nonsymbolic FontBBox: -161, -250, 1198, 972 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DEIEKJ+AdvSPSASORT FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: DEIEKJ+AdvSPSASORT Flags: Symbolic FontBBox: -281, -437, 1343, 989 FontFile3: true EncodingDictionary: Differences: true Font: BaseFont: DEHIPD+AdvPSJOANNA-SB FontSubset: true FirstChar: 49 LastChar: 117 FontDescriptor: FontName: DEHIPD+AdvPSJOANNA-SB Flags: Serif, Nonsymbolic FontBBox: -145, -239, 1000, 812 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DEHHOA+AdvPSJOANNA-I FontSubset: true FirstChar: 44 LastChar: 222 FontDescriptor: FontName: DEHHOA+AdvPSJOANNA-I Flags: Serif, Nonsymbolic FontBBox: -156, -239, 1000, 812 FontFile3: true Encoding: MacRomanEncoding Font: BaseFont: DEHHOB+AdvPSJOANNA-B FontSubset: true FirstChar: 48 LastChar: 117 FontDescriptor: FontName: DEHHOB+AdvPSJOANNA-B Flags: Nonsymbolic FontBBox: -166, -239, 1000, 812 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DEHHOC+AdvPSJOANNA FontSubset: true FirstChar: 30 LastChar: 150 FontDescriptor: FontName: DEHHOC+AdvPSJOANNA Flags: Serif, Nonsymbolic FontBBox: -135, -239, 1000, 812 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: DEHIAH+AdvTTec369687+20 FontSubset: true FirstChar: 150 LastChar: 150 FontDescriptor: FontName: DEHIAH+AdvTTec369687+20 Flags: Nonsymbolic FontBBox: -208, -208, 1062, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DEHHJP+AdvMETAB-R FontSubset: true FirstChar: 45 LastChar: 223 FontDescriptor: FontName: DEHHJP+AdvMETAB-R Flags: Serif, Nonsymbolic FontBBox: -114, -218, 1197, 781 FontFile3: true Encoding: MacRomanEncoding Font: BaseFont: DEHHPF+AdvTTec369687 FontSubset: true FirstChar: 60 LastChar: 169 FontDescriptor: FontName: DEHHPF+AdvTTec369687 Flags: Nonsymbolic FontBBox: -72, -208, 927, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DEHHKA+AdvMETAN-R FontSubset: true FirstChar: 44 LastChar: 222 FontDescriptor: FontName: DEHHKA+AdvMETAN-R Flags: Nonsymbolic FontBBox: -93, -197, 1166, 781 FontFile3: true Encoding: MacRomanEncoding Font: BaseFont: DEHLBG+Helvetica-Bold FontSubset: true FirstChar: 40 LastChar: 98 FontDescriptor: FontName: DEHLBG+Helvetica-Bold Flags: Nonsymbolic, ForceBold FontBBox: -170, -228, 1003, 962 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DEHIAG+AdvTT3713a231+20 FontSubset: true FirstChar: 129 LastChar: 129 FontDescriptor: FontName: DEHIAG+AdvTT3713a231+20 Flags: Nonsymbolic FontBBox: -468, -208, 1708, 843 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DEHHOD+AdvTTec369687+22 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: DEHHOD+AdvTTec369687+22 Flags: Symbolic FontBBox: -156, -208, 802, 906 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: DEHHPE+AdvP4C4E74 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: DEHHPE+AdvP4C4E74 Flags: Symbolic FontBBox: -20, -958, 1114, 770 FontFile3: true EncodingDictionary: Differences: true Font: BaseFont: DEIEJI+AdvTTc6ee16d2.I FontSubset: true FirstChar: 61 LastChar: 61 FontDescriptor: FontName: DEIEJI+AdvTTc6ee16d2.I Flags: Nonsymbolic FontBBox: -166, -208, 937, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DEHICH+AdvPSSym FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: DEHICH+AdvPSSym Flags: Symbolic FontBBox: -177, -291, 1083, 1010 FontFile3: true EncodingDictionary: Differences: true XMP: application/pdfdoi:10.1111/bjd.20595 10.1111/bjd.20595https://doi.org/10.1111/bjd.20595 2021-09-21trueonlinelibrary.wiley.com10.1111/bjd.20595 onlinelibrary.wiley.comtrue10.1111/bjd.205952021-09-21 VoR Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 101, 621, 103, 631 Annotation: Subtype: Link Rect: 101, 621, 103, 631 Annotation: Subtype: Link Rect: 103, 621, 108, 632 Annotation: Subtype: Link Rect: 218, 621, 220, 631 Annotation: Subtype: Link Rect: 218, 621, 220, 631 Annotation: Subtype: Link Rect: 220, 621, 226, 632 Annotation: Subtype: Link Rect: 123, 489, 306, 497 Annotation: Subtype: Link Rect: 123, 489, 324, 497 Annotation: Subtype: Link Rect: 79, 392, 151, 400 Annotation: Subtype: Link Rect: 227, 21, 379, 29 Annotation: Subtype: Link Rect: 519, 782, 595, 767 Thumb: true Page: Label: 2 Thumb: true Page: Label: 3 Thumb: true Page: Label: 4 Thumb: true Page: Label: 5 Thumb: true Page: Label: 6 Thumb: true Page: Label: 7 Thumb: true Page: Label: 8 Thumb: true Page: Label: 9 Thumb: true Page: Label: 10 Thumb: true Page: Label: 11 Annotations: Annotation: Subtype: Link Rect: 466, 625, 532, 634 Annotation: Subtype: Link Rect: 304, 613, 525, 622 Annotation: Subtype: Link Rect: 304, 601, 519, 610 Annotation: Subtype: Link Rect: 304, 589, 376, 598 Thumb: true Checksum: 38ed1b65 Type: CRC32 Checksum: d70942e300a91c4c893b5282a24d79f2 Type: MD5 Checksum: 70a7832fa1567a7f56e53f34fc341c974384995a Type: SHA-1