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Title:          Monitoring of gene expression in tacrolimus‐treated de novo renal allograft recipients facilitates individualized immunosuppression: Results of the IMAGEN study
Subject:        Brit J Clinical Pharma 2021.87:3851-3862
Keywords:       10.1111/bcp.14794 and biomarker; cytomegalovirus; pharmacodynamics; pharmacokinetics; rejection; renal transplantation; tacrolimus
Author:         Claudia Sommerer, Mercè Brunet, Klemens Budde, Olga Millán, Lluis Guirado Perich, Petra Glander, Stefan Meuer, Martin Zeier, Thomas Giese
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Producer:       Acrobat Distiller 21.0 (Windows); modified using iText 4.2.0 by 1T3XT
CreationDate:   Sat Sep 18 09:39:53 2021 CEST
ModDate:        Wed Feb  8 15:42:24 2023 CET
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Pages:          12
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Jhove (Rel. 1.22.1, 2019-04-17)
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     Item: 
      Title: Monitoring of gene expression in tacrolimus-treated de novo renal allograft recipients facilitates individualized immunosup...
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       Item: 
        Title: 1  INTRODUCTION
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       Item: 
        Title: 2  MATERIALS AND METHODS
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         Item: 
          Title: 2.1  Patient cohort
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       Item: 
        Title:   What is already known about this subject
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       Item: 
        Title:   What this study adds
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        Children: 
         Item: 
          Title: 2.2  Study design
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         Item: 
          Title: 2.3  Study objectives
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         Item: 
          Title: 2.4  Immunosuppressive regimen
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         Item: 
          Title: 2.5  Pharmacokinetic monitoring
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         Item: 
          Title: 2.6  Pharmacodynamic monitoring
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            Title: 2.6.1  Sample preparation
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           Item: 
            Title: 2.6.2  Quantitative analysis of gene expression
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          Title: 2.7  Statistical analysis
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       Item: 
        Title: 3  RESULTS
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         Item: 
          Title: 3.1  Patients
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         Item: 
          Title: 3.2  ROC analysis for group definition
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         Item: 
          Title: 3.3  AUC
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         Item: 
          Title: 3.4  Pharmacokinetic and pharmacodynamics monitoring
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         Item: 
          Title: 3.5  Efficacy
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         Item: 
          Title: 3.6  Safety
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       Item: 
        Title: 4  DISCUSSION
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         Item: 
          Title: 4.1  Nomenclature of targets and ligands
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       Item: 
        Title: ACKNOWLEDGEMENTS
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       Item: 
        Title:   COMPETING INTERESTS
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        Title:   CONTRIBUTORS
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         Item: 
          Title:   DATA AVAILABILITY STATEMENT
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       Item: 
        Title: REFERENCES
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