e509a92ef2e994c2f3e0938947c9a552 270613.pdf 39604133f0d0fbdc716e590c785d738b285f8219 270613.pdf f413fcb9257c805c568e8deb16214de056954814c7393bd11acfd5b7a8ae8802 270613.pdf Title: Effect of Polyphenols Intake on Obesity-Induced Maternal Programming Subject: Excess caloric intake and body fat accumulation lead to obesity, a complex chronic disease that represents a significant public health problem due to the health-related risk factors. There is growing evidence showing that maternal obesity can program the offspring, which influences neonatal phenotype and predispose offspring to metabolic disorders such as obesity. This increased risk may also be epigenetically transmitted across generations. Thus, there is an imperative need to find effective reprogramming approaches in order to resume normal fetal development. Polyphenols are bioactive compounds found in vegetables and fruits that exert its anti-obesity effect through its powerful anti-oxidant and anti-inflammatory activities. Polyphenol supplementation has been proven to counteract the prejudicial effects of maternal obesity programming on progeny. Indeed, some polyphenols can cross the placenta and protect the fetal predisposition against obesity. The present review summarizes the effects of dietary polyphenols on obesity-induced maternal reprogramming as an offspring anti-obesity approach. Keywords: bioactive compounds; nutraceutical; maternal obesity; adipose tissue; metabolic disorders Author: Isabela Monique Fortunato, Tanila Wood dos Santos, Lucio Fábio Caldas Ferraz, Juliana Carvalho Santos and Marcelo Lima Ribeiro Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Tue Jul 13 11:14:24 2021 CEST ModDate: Tue Jul 13 11:17:34 2021 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 13 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 1278901 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- NZLUOQ+VnURWPalladioL Type 1 Custom yes yes no 10 0 AZIWOG+URWPalladioL-Ital Type 1 Custom yes yes no 15 0 CYWDNV+URWPalladioL-Bold Type 1 Custom yes yes no 20 0 HVJNAW+URWPalladioL-Roma Type 1 Custom yes yes no 24 0 AIQCCL+VnURWPalladioL-Bold Type 1 Custom yes yes no 28 0 HGMNRX+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 36 0 MCBCCI+SourceSansRoman-Regular Type 1C Custom yes yes no 58 0 MCBCCM+SourceSansRoman.613wght Type 1C Custom yes yes no 62 0 MCBCCO+SourceSansRoman-Bold Type 1C Custom yes yes no 66 0 LHCXDL+EURM10 Type 1 Builtin yes yes no 81 0 SAUAIP+CMSY10 Type 1 Builtin yes yes no 88 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-05-20 02:31:37 CEST RepresentationInformation: 270613.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-05-19 19:01:17 CEST Size: 1278901 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 406 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@44c8afef Item: Title: Obesity and Maternal Programming Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7b69c6ba Item: Title: Adipose Tissue Programming Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@46daef40 Item: Title: Polyphenol Effect on Obesity Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@12f41634 Item: Title: Beneficial Impact of Polyphenols on Obesity-Induced Maternal Programming Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@13c27452 Item: Title: Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@262b2c86 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@371a67ec Info: Title: Effect of Polyphenols Intake on Obesity-Induced Maternal Programming Author: Isabela Monique Fortunato, Tanila Wood dos Santos, Lucio Fábio Caldas Ferraz, Juliana Carvalho Santos and Marcelo Lima Ribeiro Subject: Excess caloric intake and body fat accumulation lead to obesity, a complex chronic disease that represents a significant public health problem due to the health-related risk factors. There is growing evidence showing that maternal obesity can program the offspring, which influences neonatal phenotype and predispose offspring to metabolic disorders such as obesity. This increased risk may also be epigenetically transmitted across generations. Thus, there is an imperative need to find effective reprogramming approaches in order to resume normal fetal development. Polyphenols are bioactive compounds found in vegetables and fruits that exert its anti-obesity effect through its powerful anti-oxidant and anti-inflammatory activities. Polyphenol supplementation has been proven to counteract the prejudicial effects of maternal obesity programming on progeny. Indeed, some polyphenols can cross the placenta and protect the fetal predisposition against obesity. The present review summarizes the effects of dietary polyphenols on obesity-induced maternal reprogramming as an offspring anti-obesity approach. 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