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edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Children: Item: Title: Design Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: Statistical analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Children: Item: Title: Clinical and demographic characteristics Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: Comparison of clinical and demographic characteristics between different patterns of liver injury Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: Influence of age and injury pattern on the clinical presentation and outcome of DILI Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: Comparison of clinical and demographic characteristics between DILI patients with and without pre-existing liver conditions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: Analysis of DILI cases according to therapy received for the episode Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: Comparison of clinical and demographic characteristics between DILI and DIAIH patients Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: Therapeutic classes and individual drugs most commonly implicated in the Spanish DILI Registry Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Children: Item: Title: Abbreviations Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: Financial support Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: Conflict of interest Destination: 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FontDescriptor: FontName: FHHIAN+AdvP4C4E74 Flags: Symbolic FontBBox: -20, -958, 1114, 770 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GEOBIB+AdvOTb83ee1dd.B FontSubset: true FirstChar: 45 LastChar: 121 FontDescriptor: FontName: GEOBIB+AdvOTb83ee1dd.B Flags: Serif, Nonsymbolic FontBBox: -93, -250, 1041, 989 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GEOCIG+AdvOTb83ee1dd.B+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: GEOCIG+AdvOTb83ee1dd.B+fb Flags: Symbolic FontBBox: 19, 0, 947, 781 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: GEOBIC+AdvOT863180fb FontSubset: true FirstChar: 40 LastChar: 250 FontDescriptor: FontName: GEOBIC+AdvOT863180fb Flags: Serif, Nonsymbolic FontBBox: -72, -250, 1041, 979 FontFile3: true Encoding: WinAnsiEncoding XMP: application/pdf doi:10.1016/j.jhep.2021.01.029 Comprehensive analysis and insights gained from long-term experience of the Spanish DILI Registry Camilla Stephens Mercedes Robles-Diaz Inmaculada Medina-Caliz Miren Garcia-Cortes Aida Ortega-Alonso Judith Sanabria-Cabrera Andres Gonzalez-Jimenez Ismael Alvarez-Alvarez Mahmoud Slim Miguel Jimenez-Perez Rocio Gonzalez-Grande M. Carmen Fernández Marta Casado German Soriano Eva Román Hacibe Hallal Manuel Romero-Gomez Agustin Castiella Isabel Conde Martin Prieto Jose Maria Moreno-Planas Alvaro Giraldez J. Miguel Moreno-Sanfiel Neil Kaplowitz M. Isabel Lucena Raúl J. Andrade Participating clinical centres R.J. Andrade M.I. Lucena C. Stephens M. García Cortés M. Robles-Díaz A. Ortega-Alonso J. Pinazo B. García Muñoz R. Alcántara A. Hernández M.D. García Escaño E. del Campo I. Medina-Cáliz J. Sanabria-Cabrera A. González-Jiménez R. Sanjuán-Jiménez A. Cueto I. Álvarez-Álvarez E. Bonilla D. Di Zeo H. Niu M. Villanueva A. Papineau M. Jiménez Pérez R. González Grande S. López Ortega I. Santaella A. Ocaña P. Palomino M.C. Fernández G. Peláez A. Porcel M. Casado M. González Sánchez M. Romero-Gómez R. Millán-Domínguez B. Fombuena R. Gallego J. Ampuero J.A. del Campo R. Calle-Sanz L. Rojas A. Rojas A. Gil Gómez E. Vilar G. Soriano C. Guarner E.M. Román M.A. Quijada Manuitt R.M. Antonijoan Arbos J. Sánchez Delgado M. Vergara Gómez H. Hallal E. García Oltra J.C. Titos Arcos A. Pérez Martínez C. Sánchez Cobarro J.M. Egea Caparrós A. Castiella E. Zapata J. Arenas A. Gómez García F.J. Esandi S. Blanco P. Martínez Odriozola J. Crespo P. Iruzubieta J. Cabezas A. Giráldez Gallego E. del P. Rodríguez Seguel M. Cuaresma J. González Gallego F. Jorquera S. Sánchez Campos P. Otazua A. de Juan Gómez J. Salmerón A. Gila R. Quiles J.M. González S. Lorenzo M. Prieto I. Conde Amiel M. Berenguer M. García-Eliz J. Primo J.R. Molés A. Garayoa M. Carrascosa E. Gómez Domínguez L. Cuevas M. Farré E. Montané A.M. Barriocanal A.L. Arellano Y. Sanz R.M. Morillas M. Sala H. Masnou Ridaura M. Bruguera P. Gines S. Lens J.C. García Z. Mariño M. Hernández Guerra J.M. Moreno Sanfiel C. Boada Fernández del Campo M. Tejedor R. González Ferrer C. Fernández M. Fernández Gil J.L. Montero M. de la Mata J. Fuentes Olmo E.M. Fernández Bonilla J.M. Moreno P. Martínez-Rodenas M. Garrido C. Oliva P. Rendón J. García Samaniego A. Madejón J.L. Calleja J.L. Martínez Porras J.L. Cabriada J.M. Pérez-Moreno C. Lara Hepatotoxicity DILI epidemiology liver-related death causative agents outcome risk factors therapy in DILI drug-induced autoimmune hepatitis Journal of Hepatology, 75 (2021) 86-97. doi:10.1016/j.jhep.2021.01.029 European Association for the Study of the Liver journal Journal of Hepatology © 2021 European Association for the Study of the Liver. Published by Elsevier B.V. 0168-8278 75 1 July 2021 86-97 86 97 10.1016/j.jhep.2021.01.029 https://doi.org/10.1016/j.jhep.2021.01.029 2010-04-23 true 10.1016/j.jhep.2021.01.029 elsevier.com sciencedirect.com VoR 10.1016/j.jhep.2021.01.029 noindex 2010-04-23 true 24th December 2021 sciencedirect.com elsevier.com Elsevier 2021-12-27T15:32:04+05:30 2021-12-27T15:32:04+05:30 True 24th December 2021 Acrobat Distiller 8.1.0 (Windows) uuid:35a625e9-87a8-4591-a83f-d20c524dc2e6 uuid:d2570fd0-ce57-48f7-8ce8-c400266aad42 http://creativecommons.org/licenses/by-nc-nd/4.0/ Pages: Page: Label: 86 Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 381, 500, 450, 510 Destination: null Annotation: Subtype: Link Rect: 42, 45, 191, 53 Destination: null Annotation: Subtype: Link Rect: 45, 25, 230, 33 Destination: null Annotation: Subtype: Link Rect: 557, 760, 585, 788 Page: Label: 87 Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 192, 655, 197, 666 Destination: 1 Annotation: Subtype: Link 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