3b2b3ba9be3f5162faff855ea6ddbf42 271982.pdf 046e6582016389b2efc179c6e65acb920a6f45a9 271982.pdf f94ededc18fbbab9d4f69f769021c0b07f28e7f251e9be05b8ff020bcba970a2 271982.pdf Title: Diagnostic Performance of Ag-RDTs and NAAT for SARS-CoV2 Identification in Symptomatic Patients in Catalonia Subject: The use of rapid antigenic tests (Ag-RDTs) to diagnose a SARS-CoV-2 infection has become a common practice recently. This study aimed to evaluate performance of Abbott PanbioTM Ag-RDTs with regard to nucleic acid amplification testing (NAAT) in the early stages of the disease. A cohort of 149,026 infected symptomatic patients, reported in Catalonia from November 2020 to January 2021, was selected. The positivity rates of the two tests were compared with respect to the dates of symptom onset. Ag-RDTs presented positivity rates of 84% in the transmission phases of the disease and 31% in the pre-symptomatic period, compared to 93% and 91%, respectively, for NAAT. The detection of many false negatives with Ag-RDTs during the pre-symptomatic period demonstrates the risk of virus dissemination with this diagnostic technique if used outside the symptomatic period. Keywords: SARS-CoV-2 infection; antigen test; surveillance; pre-symptomatic; symptomatic; positivity rate Author: Luca Basile, Víctor Guadalupe-Fernández, Manuel Valdivia Guijarro, Ana Martinez Mateo, Pilar Ciruela Navas, Jacobo Mendioroz Peña and the Epidemiological Surveillance Network of Catalonia Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Mon May 17 08:25:38 2021 CEST ModDate: Mon May 17 08:25:38 2021 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 9 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 429398 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- XKYSAQ+URWPalladioL-Ital Type 1 Custom yes yes no 64 0 VAONKU+URWPalladioL-Bold Type 1 Custom yes yes no 65 0 SSNIUI+VnURWPalladioL-Bold Type 1 Custom yes yes no 66 0 GYMFCN+URWPalladioL-Roma Type 1 Custom yes yes no 67 0 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