6a1cc2699d99c8057d66bd87e8631f96  293186.pdf
8a3ec80d9abf53afb5165484bbcf85e3d035017e  293186.pdf
822f5a43f0b21bb5ae0dc587d02345da0e5fb54475684539b9a23953caae6d41  293186.pdf

Title:           Analytical Evaluation of Dried Blood Spot and Rapid Diagnostic Test as a New Strategy for Serological Community Screening for Chronic Chagas Disease
Subject:         Background: Chagas disease is a public health problem not only in Latin America, but also in other regions, including Spain, due to migration movements.
Keywords:        Trypanosoma cruzi, dried blood spot (DBS), rapid diagnostic test (RDT), serological screening, community strategies
Author:          Aroa Silgado
Creator:         Arbortext Advanced Print Publisher 10.0.1306/W Unicode
Producer:        Acrobat Distiller 7.0 (Windows)
CreationDate:    Tue Sep 14 05:35:56 2021 CEST
ModDate:         Tue Sep 14 07:04:00 2021 CEST
Custom Metadata: no
Metadata Stream: yes
Tagged:          no
UserProperties:  no
Suspects:        no
Form:            none
JavaScript:      no
Pages:           7
Encrypted:       no
Page size:       595.276 x 779.528 pts
Page rot:        0
File size:       640075 bytes
Optimized:       yes
PDF version:     1.6


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
IAMFHL+AdvPSA323                     Type 1C           WinAnsi          yes yes no     328  0
IAMFFB+AdvOT34fe1490.B               Type 1C           WinAnsi          yes yes no     307  0
IAMFFC+AdvOT01861455.I               Type 1C           WinAnsi          yes yes no     308  0
IAMFFD+AdvOT01861455.I+20            Type 1C           WinAnsi          yes yes no     309  0
IAMFFE+AdvOT01861455.I+01            Type 1C           MacRoman         yes yes no     310  0
IAMFFF+AdvPSA18C                     Type 1C           WinAnsi          yes yes no     311  0
IAMFFG+AdvOT1deab444.I               Type 1C           WinAnsi          yes yes no     306  0
IAMFFH+AdvOT1deab444.I+20            Type 1C           WinAnsi          yes yes no     313  0
IAMFFI+AdvOT6e5d2ec0                 Type 1C           WinAnsi          yes yes no     314  0
IAMFFJ+AdvOT6e5d2ec0+fb              Type 1C           Custom           yes yes yes    315  0
IAMFFK+AdvOT6e5d2ec0+21              Type 1C           WinAnsi          yes yes no     316  0
IAMFHK+AdvOT6601a1b9.BI              Type 1C           WinAnsi          yes yes no     325  0
IAMFLK+AdvOT1ef757c0                 Type 1C           WinAnsi          yes yes no     158  0
IAMFLL+AdvOT7d6df7ab.I               Type 1C           WinAnsi          yes yes no     153  0
IAMFMM+AdvTT58d178b9+03              Type 1C           Custom           yes yes yes    163  0
IAMFMN+AdvOT1ef757c0+fb              Type 1C           Custom           yes yes yes    168  0
IAMFMO+AdvOTb65e897d.B               Type 1C           WinAnsi          yes yes no     164  0
IAMFMP+AdvOTd877c31c+21              Type 1C           WinAnsi          yes yes no     154  0
IAMFNP+AdvOT1ef757c0+01              Type 1C           MacRoman         yes yes no     178  0
IAMFOA+AdvOT1ef757c0+20              Type 1C           WinAnsi          yes yes no     184  0
IAMFOB+AdvOT1ef757c0+22              Type 1C           Custom           yes yes yes    177  0
IAMIFC+AdvOTb65e897d.B+fb            Type 1C           Custom           yes yes yes    186  0
IAMIFD+AdvOTb65e897d.B+20            Type 1C           WinAnsi          yes yes no     188  0
IAMIFE+AdvTT02dee1cd.I+03            Type 1C           Custom           yes yes yes    187  0


Jhove (Rel. 1.28.0, 2023-05-18)
 Date: 2024-06-06 02:45:40 CEST
 RepresentationInformation: 293186.pdf
  ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16)
  LastModified: 2024-06-05 12:29:34 CEST
  Size: 640075
  Format: PDF
  Version: 1.6
  Status: Well-Formed, but not valid
  SignatureMatches:
   PDF-hul
  ErrorMessage: Invalid indirect destination - referenced object 'B31' cannot be found
   ID: PDF-HUL-149
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B31' cannot be found
   ID: PDF-HUL-122
   Offset: 625956
  MIMEtype: application/pdf
  Profile: Linearized PDF
  PDFMetadata: 
   Objects: 386
   FreeObjects: 1
   IncrementalUpdates: 1
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseOutlines
    Outlines: 
     Item: 
      Title: Analytical Evaluation of Dried Blood Spot and Rapid Diagnostic Test as a New Strategy for Serological Community Screening for Chronic Chagas Disease
      Destination: bmark_1398145463
      Children: 
       Item: 
        Title: Introduction
        Destination: s1
       Item: 
        Title: Materials and Methods
        Destination: s2
        Children: 
         Item: 
          Title: Study Population and Samples
          Destination: s2_1
         Item: 
          Title: Detection of IgG Anti-T. cruzi in DBS
          Destination: s2_2
         Item: 
          Title: Rapid Diagnostic Test
          Destination: s2_3
         Item: 
          Title: Statistical Analysis
          Destination: s2_4
         Item: 
          Title: Ethics Statement
          Destination: s2_5
       Item: 
        Title: Results
        Destination: s3
       Item: 
        Title: Discussion
        Destination: s4
       Item: 
        Title: Data Availability Statement
        Destination: s5
       Item: 
        Title: Ethics Statement
        Destination: s6
       Item: 
        Title: Author Contributions
        Destination: s7
       Item: 
        Title: Funding
        Destination: s8
       Item: 
        Title: Acknowledgments
        Destination: bmark_-366698314
       Item: 
        Title: References
        Destination: bmark_2090415954
   Info: 
    Title: Analytical Evaluation of Dried Blood Spot and Rapid Diagnostic Test as a New Strategy for Serological Community Screening for Chronic Chagas Disease
    Author: Aroa Silgado
    Subject: Background: Chagas disease is a public health problem not only in Latin America, but also in other regions, including Spain, due to migration movements.
    Keywords: Trypanosoma cruzi, dried blood spot (DBS), rapid diagnostic test (RDT), serological screening, community strategies
    Creator: Arbortext Advanced Print Publisher 10.0.1306/W Unicode
    Producer: Acrobat Distiller 7.0 (Windows)
    CreationDate: Tue Sep 14 05:35:56 CEST 2021
    ModDate: Tue Sep 14 07:04:00 CEST 2021
   ID: 0x8c1b99197acba76b5c984955ad178860, 0x25373a7bbecfc84098f298e8a812a6da
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 2008
      ImageHeight: 1151
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 886
      ImageHeight: 709
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 2008
      ImageHeight: 882
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 886
      ImageHeight: 840
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
   Fonts: 
    Type1: 
     Font: 
      BaseFont: IAMFMM+AdvTT58d178b9+03
      FontSubset: true
      FirstChar: 0
      LastChar: 0
      FontDescriptor: 
       FontName: IAMFMM+AdvTT58d178b9+03
       Flags: Symbolic
       FontBBox: -645, -354, 916, 895
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: IAMFMO+AdvOTb65e897d.B
      FontSubset: true
      FirstChar: 49
      LastChar: 117
      FontDescriptor: 
       FontName: IAMFMO+AdvOTb65e897d.B
       Flags: Nonsymbolic
       FontBBox: -20, -250, 968, 854
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: IAMFHK+AdvOT6601a1b9.BI
      FontSubset: true
      FirstChar: 42
      LastChar: 122
      FontDescriptor: 
       FontName: IAMFHK+AdvOT6601a1b9.BI
       Flags: Nonsymbolic
       FontBBox: -125, -208, 1020, 968
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: IAMFHL+AdvPSA323
      FontSubset: true
      FirstChar: 180
      LastChar: 180
      FontDescriptor: 
       FontName: IAMFHL+AdvPSA323
       Flags: Nonsymbolic
       FontBBox: -156, -239, 1104, 770
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: IAMFMN+AdvOT1ef757c0+fb
      FontSubset: true
      FirstChar: 1
      LastChar: 3
      FontDescriptor: 
       FontName: IAMFMN+AdvOT1ef757c0+fb
       Flags: Symbolic
       FontBBox: 0, -10, 781, 708
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: IAMFOB+AdvOT1ef757c0+22
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: IAMFOB+AdvOT1ef757c0+22
       Flags: Symbolic
       FontBBox: -135, -166, 697, 916
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: IAMFFG+AdvOT1deab444.I
      FontSubset: true
      FirstChar: 40
      LastChar: 242
      FontDescriptor: 
       FontName: IAMFFG+AdvOT1deab444.I
       Flags: Nonsymbolic
       FontBBox: -135, -208, 968, 947
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: IAMFNP+AdvOT1ef757c0+01
      FontSubset: true
      FirstChar: 245
      LastChar: 245
      FontDescriptor: 
       FontName: IAMFNP+AdvOT1ef757c0+01
       Flags: Serif, Nonsymbolic
       FontBBox: -20, -250, 947, 854
       FontFile3: true
      Encoding: MacRomanEncoding
     Font: 
      BaseFont: IAMFFB+AdvOT34fe1490.B
      FontSubset: true
      FirstChar: 40
      LastChar: 121
      FontDescriptor: 
       FontName: IAMFFB+AdvOT34fe1490.B
       Flags: Nonsymbolic
       FontBBox: -52, -208, 937, 968
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: IAMFFC+AdvOT01861455.I
      FontSubset: true
      FirstChar: 42
      LastChar: 122
      FontDescriptor: 
       FontName: IAMFFC+AdvOT01861455.I
       Flags: Nonsymbolic
       FontBBox: -125, -208, 1000, 937
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: IAMFFD+AdvOT01861455.I+20
      FontSubset: true
      FirstChar: 134
      LastChar: 134
      FontDescriptor: 
       FontName: IAMFFD+AdvOT01861455.I+20
       Flags: Nonsymbolic
       FontBBox: -156, -156, 1010, 718
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: IAMFFE+AdvOT01861455.I+01
      FontSubset: true
      FirstChar: 245
      LastChar: 245
      FontDescriptor: 
       FontName: IAMFFE+AdvOT01861455.I+01
       Flags: Nonsymbolic
       FontBBox: -41, -166, 1125, 927
       FontFile3: true
      Encoding: MacRomanEncoding
     Font: 
      BaseFont: IAMFFF+AdvPSA18C
      FontSubset: true
      FirstChar: 180
      LastChar: 180
      FontDescriptor: 
       FontName: IAMFFF+AdvPSA18C
       Flags: Nonsymbolic
       FontBBox: -156, -208, 1125, 802
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: IAMFOA+AdvOT1ef757c0+20
      FontSubset: true
      FirstChar: 146
      LastChar: 151
      FontDescriptor: 
       FontName: IAMFOA+AdvOT1ef757c0+20
       Flags: Nonsymbolic
       FontBBox: -135, -187, 1010, 833
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: IAMFFH+AdvOT1deab444.I+20
      FontSubset: true
      FirstChar: 134
      LastChar: 146
      FontDescriptor: 
       FontName: IAMFFH+AdvOT1deab444.I+20
       Flags: Nonsymbolic
       FontBBox: -156, -145, 1000, 718
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: IAMFLL+AdvOT7d6df7ab.I
      FontSubset: true
      FirstChar: 40
      LastChar: 169
      FontDescriptor: 
       FontName: IAMFLL+AdvOT7d6df7ab.I
       Flags: Nonsymbolic
       FontBBox: -135, -250, 1000, 854
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: IAMFFI+AdvOT6e5d2ec0
      FontSubset: true
      FirstChar: 37
      LastChar: 124
      FontDescriptor: 
       FontName: IAMFFI+AdvOT6e5d2ec0
       Flags: Nonsymbolic
       FontBBox: -62, -208, 895, 958
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: IAMFMP+AdvOTd877c31c+21
      FontSubset: true
      FirstChar: 153
      LastChar: 153
      FontDescriptor: 
       FontName: IAMFMP+AdvOTd877c31c+21
       Flags: Nonsymbolic
       FontBBox: -10, -250, 1145, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: IAMIFC+AdvOTb65e897d.B+fb
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: IAMIFC+AdvOTb65e897d.B+fb
       Flags: Symbolic
       FontBBox: 0, -10, 843, 697
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: IAMFFJ+AdvOT6e5d2ec0+fb
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: IAMFFJ+AdvOT6e5d2ec0+fb
       Flags: Symbolic
       FontBBox: 0, 0, 500, 708
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: IAMIFE+AdvTT02dee1cd.I+03
      FontSubset: true
      FirstChar: 0
      LastChar: 0
      FontDescriptor: 
       FontName: IAMIFE+AdvTT02dee1cd.I+03
       Flags: Symbolic
       FontBBox: -416, -354, 916, 864
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: IAMFFK+AdvOT6e5d2ec0+21
      FontSubset: true
      FirstChar: 153
      LastChar: 153
      FontDescriptor: 
       FontName: IAMFFK+AdvOT6e5d2ec0+21
       Flags: Nonsymbolic
       FontBBox: 0, -10, 906, 760
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: IAMIFD+AdvOTb65e897d.B+20
      FontSubset: true
      FirstChar: 146
      LastChar: 146
      FontDescriptor: 
       FontName: IAMIFD+AdvOTb65e897d.B+20
       Flags: Nonsymbolic
       FontBBox: -125, -177, 1052, 822
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: IAMFLK+AdvOT1ef757c0
      FontSubset: true
      FirstChar: 37
      LastChar: 252
      FontDescriptor: 
       FontName: IAMFLK+AdvOT1ef757c0
       Flags: Serif, Nonsymbolic
       FontBBox: -20, -250, 947, 854
       FontFile3: true
      Encoding: WinAnsiEncoding
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="3.1-701">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about=""
            xmlns:pdf="http://ns.adobe.com/pdf/1.3/">
         <pdf:Producer>Acrobat Distiller 7.0 (Windows)</pdf:Producer>
         <pdf:Keywords>Trypanosoma cruzi, dried blood spot (DBS), rapid diagnostic test (RDT), serological screening, community strategies</pdf:Keywords>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xap="http://ns.adobe.com/xap/1.0/">
         <xap:CreateDate>2021-09-14T11:35:56+08:00</xap:CreateDate>
         <xap:ModifyDate>2021-09-14T13:04+08:00</xap:ModifyDate>
         <xap:CreatorTool>Arbortext Advanced Print Publisher 10.0.1306/W Unicode</xap:CreatorTool>
         <xap:MetadataDate>2021-09-14T13:04+08:00</xap:MetadataDate>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:dc="http://purl.org/dc/elements/1.1/">
         <dc:format>application/pdf</dc:format>
         <dc:creator>
            <rdf:Seq>
               <rdf:li>Aroa Silgado</rdf:li>
               <rdf:li>L&amp;iacute</rdf:li>
               <rdf:li>dia Gual-Gonzalez</rdf:li>
               <rdf:li>Adrián Sánchez-Montalvá</rdf:li>
               <rdf:li>Inés Oliveira-Souto</rdf:li>
               <rdf:li>Lidia Goterris</rdf:li>
               <rdf:li>Nuria Serre-Delcor</rdf:li>
               <rdf:li>Juliana Esperalba</rdf:li>
               <rdf:li>Jordi Gomez-i-Prat</rdf:li>
               <rdf:li>Candela Fernández-Naval</rdf:li>
               <rdf:li>Israel Molina</rdf:li>
               <rdf:li>Tomas Pumarola</rdf:li>
               <rdf:li>Elena Sulleiro</rdf:li>
            </rdf:Seq>
         </dc:creator>
         <dc:description>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Background: Chagas disease is a public health problem not only in Latin America, but also in other regions, including Spain, due to migration movements.</rdf:li>
            </rdf:Alt>
         </dc:description>
         <dc:title>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Analytical Evaluation of Dried Blood Spot and Rapid Diagnostic Test as a New Strategy for Serological Community Screening for Chronic Chagas Disease</rdf:li>
            </rdf:Alt>
         </dc:title>
         <dc:subject>
            <rdf:Bag>
               <rdf:li>Trypanosoma cruzi</rdf:li>
               <rdf:li>dried blood spot (DBS)</rdf:li>
               <rdf:li>rapid diagnostic test (RDT)</rdf:li>
               <rdf:li>serological screening</rdf:li>
               <rdf:li>community strategies</rdf:li>
            </rdf:Bag>
         </dc:subject>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xapMM="http://ns.adobe.com/xap/1.0/mm/">
         <xapMM:DocumentID>uuid:8bc6c4fe-f9b7-4617-b3ee-e364a664445f</xapMM:DocumentID>
         <xapMM:InstanceID>uuid:ff4b0685-4bf9-46ed-b71f-5b0be98ea1f9</xapMM:InstanceID>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Label: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 175, 593, 531, 614
      Annotation: 
       Subtype: Link
       Rect: 175, 570, 526, 591
      Annotation: 
       Subtype: Link
       Rect: 175, 547, 480, 568
      Annotation: 
       Subtype: Link
       Rect: 175, 524, 514, 545
      Annotation: 
       Subtype: Link
       Rect: 175, 501, 336, 522
      Annotation: 
       Subtype: Link
       Rect: 45, 29, 182, 36
      Annotation: 
       Subtype: Link
       Rect: 191, 29, 249, 36
      Annotation: 
       Subtype: Link
       Rect: 406, 29, 549, 36
      Annotation: 
       Subtype: Link
       Rect: 87, 522, 158, 530
      Annotation: 
       Subtype: Link
       Rect: 97, 363, 158, 370
      Annotation: 
       Subtype: Link
       Rect: 63, 64, 158, 71
      Annotation: 
       Subtype: Link
       Rect: 475, 736, 549, 743
      Annotation: 
       Subtype: Link
       Rect: 456, 728, 549, 735
      Annotation: 
       Subtype: Link
       Rect: 450, 720, 549, 727
      Annotation: 
       Subtype: Link
       Rect: 45, 719, 291, 753
      Annotation: 
       Subtype: Link
       Rect: 521, 678, 549, 706
    Page: 
     Label: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 155, 567, 283, 577
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 116, 533, 212, 542
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 222, 510, 289, 519
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 45, 498, 88, 508
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 48, 487, 144, 496
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 173, 464, 283, 473
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 92, 395, 188, 404
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 191, 372, 283, 381
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 67, 314, 129, 324
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 158, 268, 229, 278
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 109, 245, 174, 255
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 48, 211, 128, 220
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 247, 176, 289, 186
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 45, 165, 96, 174
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 126, 142, 244, 151
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 48, 107, 122, 117
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 129, 107, 207, 117
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 225, 84, 289, 94
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 306, 613, 324, 622
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 396, 590, 481, 599
       Destination: 87
      Annotation: 
       Subtype: Link
       Rect: 486, 590, 549, 599
       Destination: 87
      Annotation: 
       Subtype: Link
       Rect: 306, 578, 325, 588
       Destination: 87
      Annotation: 
       Subtype: Link
       Rect: 309, 567, 398, 576
       Destination: 87
      Annotation: 
       Subtype: Link
       Rect: 459, 555, 522, 565
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 380, 394, 544, 404
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 399, 176, 432, 185
       Destination: 33
      Annotation: 
       Subtype: Link
       Rect: 45, 29, 182, 36
      Annotation: 
       Subtype: Link
       Rect: 191, 29, 249, 36
      Annotation: 
       Subtype: Link
       Rect: 406, 29, 549, 36
    Page: 
     Label: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 157, 342, 228, 352
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 45, 29, 182, 36
      Annotation: 
       Subtype: Link
       Rect: 191, 29, 249, 36
      Annotation: 
       Subtype: Link
       Rect: 406, 29, 549, 36
    Page: 
     Label: 4
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 90, 555, 124, 565
       Destination: 41
      Annotation: 
       Subtype: Link
       Rect: 239, 463, 272, 473
       Destination: 41
      Annotation: 
       Subtype: Link
       Rect: 207, 371, 240, 381
       Destination: 53
      Annotation: 
       Subtype: Link
       Rect: 45, 29, 182, 36
      Annotation: 
       Subtype: Link
       Rect: 191, 29, 249, 36
      Annotation: 
       Subtype: Link
       Rect: 406, 29, 549, 36
    Page: 
     Label: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 267, 259, 289, 268
       Destination: 87
      Annotation: 
       Subtype: Link
       Rect: 45, 247, 86, 257
       Destination: 87
      Annotation: 
       Subtype: Link
       Rect: 91, 247, 220, 257
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 48, 213, 152, 222
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 238, 155, 289, 165
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 45, 144, 62, 153
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 220, 121, 281, 130
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 340, 708, 421, 717
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 309, 639, 418, 648
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 424, 639, 544, 648
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 330, 547, 404, 556
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 309, 386, 382, 395
       Destination: 87
      Annotation: 
       Subtype: Link
       Rect: 340, 294, 453, 303
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 368, 259, 436, 269
       Destination: 87
      Annotation: 
       Subtype: Link
       Rect: 441, 259, 505, 269
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 509, 259, 549, 269
       Destination: 87
      Annotation: 
       Subtype: Link
       Rect: 306, 248, 324, 257
       Destination: 87
      Annotation: 
       Subtype: Link
       Rect: 330, 248, 419, 257
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 426, 248, 544, 257
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 509, 236, 549, 246
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 306, 225, 324, 234
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 479, 225, 547, 234
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 306, 213, 373, 223
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 457, 179, 549, 188
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 306, 167, 324, 177
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 309, 133, 422, 142
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 427, 133, 510, 142
       Destination: 87
      Annotation: 
       Subtype: Link
       Rect: 45, 29, 182, 36
      Annotation: 
       Subtype: Link
       Rect: 191, 29, 249, 36
      Annotation: 
       Subtype: Link
       Rect: 406, 29, 549, 36
    Page: 
     Label: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 89, 558, 190, 568
       Destination: 87
      Annotation: 
       Subtype: Link
       Rect: 278, 535, 289, 545
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 45, 524, 152, 533
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 48, 466, 121, 476
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 125, 466, 196, 476
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 200, 466, 273, 476
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 278, 466, 289, 476
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 45, 455, 154, 464
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 158, 455, 254, 464
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 68, 137, 159, 144
      Annotation: 
       Subtype: Link
       Rect: 170, 99, 257, 106
      Annotation: 
       Subtype: Link
       Rect: 170, 70, 253, 78
      Annotation: 
       Subtype: Link
       Rect: 382, 156, 460, 163
      Annotation: 
       Subtype: Link
       Rect: 501, 127, 549, 135
      Annotation: 
       Subtype: Link
       Rect: 316, 118, 353, 125
      Annotation: 
       Subtype: Link
       Rect: 502, 89, 549, 97
      Annotation: 
       Subtype: Link
       Rect: 45, 29, 182, 36
      Annotation: 
       Subtype: Link
       Rect: 191, 29, 249, 36
      Annotation: 
       Subtype: Link
       Rect: 406, 29, 549, 36
    Page: 
     Label: 7
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 83, 700, 182, 708
      Annotation: 
       Subtype: Link
       Rect: 143, 662, 218, 670
      Annotation: 
       Subtype: Link
       Rect: 123, 624, 212, 632
      Annotation: 
       Subtype: Link
       Rect: 98, 586, 184, 594
      Annotation: 
       Subtype: Link
       Rect: 68, 539, 159, 546
      Annotation: 
       Subtype: Link
       Rect: 162, 501, 230, 508
      Annotation: 
       Subtype: Link
       Rect: 107, 453, 183, 461
      Annotation: 
       Subtype: Link
       Rect: 90, 406, 198, 413
      Annotation: 
       Subtype: Link
       Rect: 177, 377, 263, 385
      Annotation: 
       Subtype: Link
       Rect: 196, 339, 279, 347
      Annotation: 
       Subtype: Link
       Rect: 68, 301, 162, 309
      Annotation: 
       Subtype: Link
       Rect: 109, 263, 191, 271
      Annotation: 
       Subtype: Link
       Rect: 230, 225, 289, 233
      Annotation: 
       Subtype: Link
       Rect: 187, 197, 270, 204
      Annotation: 
       Subtype: Link
       Rect: 83, 168, 158, 176
      Annotation: 
       Subtype: Link
       Rect: 366, 681, 435, 689
      Annotation: 
       Subtype: Link
       Rect: 329, 643, 419, 651
      Annotation: 
       Subtype: Link
       Rect: 380, 605, 470, 613
      Annotation: 
       Subtype: Link
       Rect: 371, 558, 468, 565
      Annotation: 
       Subtype: Link
       Rect: 347, 510, 416, 518
      Annotation: 
       Subtype: Link
       Rect: 467, 482, 547, 489
      Annotation: 
       Subtype: Link
       Rect: 347, 444, 415, 451
      Annotation: 
       Subtype: Link
       Rect: 454, 425, 539, 432
      Annotation: 
       Subtype: Link
       Rect: 524, 396, 549, 404
      Annotation: 
       Subtype: Link
       Rect: 316, 387, 368, 394
      Annotation: 
       Subtype: Link
       Rect: 500, 368, 549, 375
      Annotation: 
       Subtype: Link
       Rect: 316, 358, 532, 366
      Annotation: 
       Subtype: Link
       Rect: 318, 206, 469, 214
      Annotation: 
       Subtype: Link
       Rect: 45, 29, 182, 36
      Annotation: 
       Subtype: Link
       Rect: 191, 29, 249, 36
      Annotation: 
       Subtype: Link
       Rect: 406, 29, 549, 36
  Checksum: e156f629
   Type: CRC32
  Checksum: 6a1cc2699d99c8057d66bd87e8631f96
   Type: MD5
  Checksum: 8a3ec80d9abf53afb5165484bbcf85e3d035017e
   Type: SHA-1
  Checksum: 822f5a43f0b21bb5ae0dc587d02345da0e5fb54475684539b9a23953caae6d41
   Type: SHA-256