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Title:           Identifying Changes in Peripheral Lymphocyte Subpopulations in Adult Onset Type 1 Diabetes
Subject:         T- and B-lymphocytes play an important role in the pathogenesis of type 1 diabetes (T1D), a chronic disease caused by the autoimmune destruction of the insulin-producing cells in the pancreatic islets
Keywords:        immunomonitoring, lymphocyte subpopulations, flow cytometry, type 1 diabetes, onset, adult, follow-up
Author:          Aina Teniente-Serra; Eduarda Pizarro; Bibiana Quirant-Sánchez; Marco A. Fernández; Marta Vives-Pi; Eva M. Martinez-Caceres
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     Item: 
      Title: Identifying Changes in Peripheral Lymphocyte Subpopulations in Adult Onset Type 1 Diabetes
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       Item: 
        Title: Introduction
        Destination: s1
       Item: 
        Title: Materials and Methods
        Destination: s2
        Children: 
         Item: 
          Title: Study Subjects and Design
          Destination: s2_1
         Item: 
          Title: Sample Collection
          Destination: s2_2
         Item: 
          Title: Flow Cytometry and Analysis
          Destination: s2_3
         Item: 
          Title: Quantification of Absolute Cell Numbers
          Destination: s2_4
         Item: 
          Title: Statistical Analysis
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       Item: 
        Title: Results
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        Children: 
         Item: 
          Title: Lymphocyte Subsets Are Altered at the Early Stages of T1D
          Destination: s3_1
         Item: 
          Title: Naïve T Cells Are Increased at the Onset of T1D Whereas There Is a Decrease in Effector Memory Subsets
          Destination: s3_2
         Item: 
          Title: At the Onset of T1D There Is a Decrease in Treg Subpopulations
          Destination: s3_3
         Item: 
          Title: B Transitional Cells Are Decreased Whereas IgM-only B Cells Are Increased at the Onset of the Disease
          Destination: s3_4
         Item: 
          Title: Naïve Double Positive CD4 and CD8 T Cells Are Increased at Onset of T1D
          Destination: s3_5
         Item: 
          Title: Changes in Lymphocyte Subpopulations in Patients at Established Disease
          Destination: s3_6
         Item: 
          Title: Peripheral Lymphocyte Subpopulations as Candidate Biomarkers in the Diagnosis of T1D
          Destination: s3_7
       Item: 
        Title: Discussion
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       Item: 
        Title: Data Availability Statement
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       Item: 
        Title: Ethics Statement
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       Item: 
        Title: Author Contributions
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       Item: 
        Title: Funding
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       Item: 
        Title: Acknowledgments
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       Item: 
        Title: Supplementary Material
        Destination: bmark_386646472
       Item: 
        Title: References
        Destination: bmark_2090415954
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    Title: Identifying Changes in Peripheral Lymphocyte Subpopulations in Adult Onset Type 1 Diabetes
    Author: Aina Teniente-Serra; Eduarda Pizarro; Bibiana Quirant-Sánchez; Marco A. Fernández; Marta Vives-Pi; Eva M. Martinez-Caceres
    Subject: T- and B-lymphocytes play an important role in the pathogenesis of type 1 diabetes (T1D), a chronic disease caused by the autoimmune destruction of the insulin-producing cells in the pancreatic islets
    Keywords: immunomonitoring, lymphocyte subpopulations, flow cytometry, type 1 diabetes, onset, adult, follow-up
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   Type: CRC32
  Checksum: 870f62f4faaa7052db206286e810d745
   Type: MD5
  Checksum: a3170985a07299757963ae864efe8ad3fcb34824
   Type: SHA-1
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   Type: SHA-256