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Item: Title: 2.2 Fish and Experimental Design Destination: s2_2 Item: Title: 2.3 Humoral Immune Parameters Destination: s2_3 Children: Item: Title: 2.3.1 Peroxidase Activity Destination: s2_3_1 Item: Title: 2.3.2 Protease Activity Destination: s2_3_2 Item: Title: 2.3.3 Antiprotease Activity Destination: s2_3_3 Item: Title: 2.3.4 Lysozyme Activity Destination: s2_3_4 Item: Title: 2.3.5 Bactericidal Activity Destination: s2_3_5 Item: Title: 2.4 Bacterial Challenge Destination: s2_4 Item: Title: 2.5 Transcriptional Analysis Destination: s2_5 Children: Item: Title: 2.5.1 RNA Isolation and Quality Control Destination: s2_5_1 Item: Title: 2.5.2 Microarray Design and Analysis Destination: s2_5_2 Item: Title: 2.5.3 Functional Network Analyses: Interactomes Destination: s2_5_3 Item: Title: 2.6 Ethics Statement Destination: s2_6 Item: Title: 2.7 Statistics Destination: s2_7 Item: Title: 3 Results Destination: s3 Children: Item: Title: 3.1 Growth Performance Destination: s3_1 Item: Title: 3.2 Non-Specific Humoral Immune Parameters Destination: s3_2 Item: Title: 3.3 Head Kidney Transcriptomic and Microarrays Destination: s3_3 Item: Title: 3.4 Enrichment Analyses Destination: s3_4 Item: Title: 3.5 In Vivo Bacterial Challenge Test Destination: s3_5 Item: Title: 4 Discussion Destination: s4 Children: Item: Title: 4.1 Transcription Factors Destination: s4_1 Item: Title: 4.2 Cell Response Destination: s4_2 Item: Title: 4.3 Innate and Adaptive Response Destination: s4_3 Item: Title: 4.4 Inflammatory Response and Immune Signaling Destination: s4_4 Item: Title: 5 Conclusions Destination: s5 Item: Title: Data Availability Statement Destination: s6 Item: Title: Ethics Statement Destination: s7 Item: Title: Author Contributions Destination: s8 Item: Title: Funding Destination: s9 Item: Title: Supplementary Material Destination: bmark_386646472 Item: Title: References Destination: bmark_2090415954 Info: Title: A Bioactive Extract Rich in Triterpenic Acid and Polyphenols from Olea europaea Promotes Systemic Immunity and Protects Atlantic Salmon Smolts Against Furunculosis Author: Ricardo Salomó Subject: In the present study, the modulation of the transcriptional immune response (microarray analysis) in the head kidney (HK) of the anadromous fish Atlantic salmon (Salmo salar) fed a diet supplemented with an olive fruit extract (AQUOLIVE®) was evaluat Keywords: feed additive, Olea europaea, aquaculture, Aeromonas salmonicida, challenge, systemic immunity, Salmo salar, immune homeostasis Creator: Arbortext Advanced Print Publisher 10.0.1306/W Unicode Producer: Acrobat Distiller 7.0 (Windows) CreationDate: Thu Nov 11 01:58:48 CET 2021 ModDate: Thu Nov 11 02:43:58 CET 2021 ID: 0xd33ceed59fced769a98c0c5c5892f64b, 0x4348d4a7a5741449918f4f705bf784fb Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1558 ImageHeight: 1526 ColorSpace: RGB BitsPerSample: 8 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GLAMNL+AdvOT1ef757c0+fb Flags: Symbolic FontBBox: 0, -10, 781, 708 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true XMP: Acrobat Distiller 7.0 (Windows) feed additive, Olea europaea, aquaculture, Aeromonas salmonicida, challenge, systemic immunity, Salmo salar, immune homeostasis 2021-11-11T09:43:58+08:00 2021-11-11T08:58:48+08:00 Arbortext Advanced Print Publisher 10.0.1306/W Unicode 2021-11-11T09:43:58+08:00 application/pdf A Bioactive Extract Rich in Triterpenic Acid and Polyphenols from Olea europaea Promotes Systemic Immunity and Protects Atlantic Salmon Smolts Against Furunculosis Ricardo Salom&oacute n M. Dolors Furones Felipe E. Reyes-L&oacute pez Lluis Tort Joana P. Firmino M. Angeles Esteban Crist&oacute bal Espinosa Ru&iacute z José C. Quintela José M. Pinilla-Rosas Eva Vallejos-Vidal Enric Gisbert In the present study, the modulation of the transcriptional immune response (microarray analysis) in the head kidney (HK) of the anadromous fish Atlantic salmon (Salmo salar) fed a diet supplemented with an olive fruit extract (AQUOLIVE®) was evaluat feed additive Olea europaea aquaculture Aeromonas salmonicida challenge systemic immunity Salmo salar immune homeostasis uuid:f9c60c53-a10e-498b-b87a-2bc7c0876d67 uuid:26ad36ae-caa6-45e1-9731-bb5b48ff2af2 Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 175, 598, 440, 619 Annotation: Subtype: Link Rect: 175, 575, 504, 596 Annotation: Subtype: Link Rect: 175, 552, 477, 573 Annotation: Subtype: Link Rect: 175, 529, 498, 550 Annotation: Subtype: Link Rect: 175, 506, 488, 527 Annotation: Subtype: Link Rect: 175, 483, 302, 504 Annotation: Subtype: Link Rect: 45, 29, 116, 36 Annotation: Subtype: Link Rect: 125, 29, 183, 36 Annotation: Subtype: Link Rect: 408, 29, 549, 36 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SHA-256