abb5ad4c4af0c402ad862c8fa4e8e858 pmc_33727799.pdf 0b9be094bffa7d754f3496a79035485a06d9635c pmc_33727799.pdf 2412cdedc1a528825db1a0d2865e1e1cb0281ba9b05a035722b1ddc3f12d1441 pmc_33727799.pdf Title: PPA_A_297581 543..548 Creator: Arbortext Advanced Print Publisher 11.0.3433/W Unicode Producer: PDFlib+PDI 9.0.3p4 (C++/Win32) CreationDate: Fri Mar 5 05:56:28 2021 CET ModDate: Fri Mar 5 05:59:05 2021 CET Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 6 Encrypted: no Page size: 612 x 792 pts (letter) Page rot: 0 File size: 270276 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- OZDFOI+GillSansMT-Identity-H CID TrueType Identity-H yes yes yes 51 0 VXCXHL+GillSansMT-Italic-Identity-H CID TrueType Identity-H yes yes yes 64 0 MQPHVJ+GillSansMT-Bold-Identity-H CID TrueType Identity-H yes yes yes 245 0 NTRIBV+TimesNewRomanPSMT-Identity-H CID TrueType Identity-H yes yes yes 250 0 JGXAML+MuseeBold Type 1C Custom yes yes yes 313 0 YVXRCM+GillSansStd-Condensed Type 1C Custom yes yes yes 427 0 ADOQAO+Musee Type 1C Custom yes yes yes 446 0 ECEHRU+TimesNewRomanPS-ItalicMT-Identity-H CID TrueType Identity-H yes yes yes 439 0 RQHQQN+TimesNewRomanPSMT-Identity-H CID TrueType Identity-H yes yes yes 494 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2022-03-10 02:58:20 CET RepresentationInformation: pmc_33727799.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2021-03-22 03:45:34 CET Size: 270276 Format: PDF Version: 1.5 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'refcit0004' cannot be found Offset: 9700 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'refcit0005' cannot be found Offset: 9700 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'refcit0006' cannot be found Offset: 9700 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'refcit0017' cannot be found Offset: 9700 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'refcit0018' cannot be found Offset: 9700 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'refcit0020' cannot be found Offset: 9700 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'refcit0021' cannot be found Offset: 9700 MIMEtype: application/pdf Profile: Tagged PDF PDFMetadata: Objects: 0 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: Plain Language Summary Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: Patients and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Children: Item: Title: Phase I: Interviews Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: Phase II: Focus Group Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: Discussion and Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Item: Title: Data Sharing Statement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7 Item: Title: Ethics Approval and Informed Consent Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cbd213e Item: Title: Consent for Publication Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247 Item: Title: Acknowledgments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3ecd23d9 Item: Title: Author Contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@569cfc36 Item: Title: Funding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@43bd930a Item: Title: Disclosure Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@33723e30 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@64f6106c Filters: FilterPipeline: FlateDecode Fonts: Type0: Font: BaseFont: VXCXHL+GillSansMT-Italic-Identity-H Encoding: Identity-H ToUnicode: true Font: BaseFont: OZDFOI+GillSansMT-Identity-H Encoding: Identity-H ToUnicode: true Font: BaseFont: MQPHVJ+GillSansMT-Bold-Identity-H Encoding: Identity-H ToUnicode: true Font: BaseFont: ECEHRU+TimesNewRomanPS-ItalicMT-Identity-H Encoding: Identity-H ToUnicode: true Font: BaseFont: NTRIBV+TimesNewRomanPSMT-Identity-H Encoding: Identity-H ToUnicode: true Font: BaseFont: RQHQQN+TimesNewRomanPSMT-Identity-H Encoding: Identity-H ToUnicode: true Type1: Font: BaseFont: JGXAML+MuseeBold FontSubset: true FirstChar: 1 LastChar: 18 FontDescriptor: FontName: MuseeBold Flags: Nonsymbolic, ForceBold FontBBox: -213, -380, 1656, 1102 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: YVXRCM+GillSansStd-Condensed FontSubset: true FirstChar: 1 LastChar: 48 FontDescriptor: FontName: GillSansStd-Condensed Flags: Nonsymbolic FontBBox: -116, -253, 1006, 868 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: ADOQAO+Musee FontSubset: true FirstChar: 1 LastChar: 16 FontDescriptor: FontName: Musee Flags: Nonsymbolic FontBBox: -200, -358, 1652, 1122 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true CIDFontType2: Font: BaseFont: NTRIBV+TimesNewRomanPSMT CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: TimesNewRomanPSMT Flags: Nonsymbolic FontBBox: -568, -307, 2000, 1007 FontFile2: true Font: BaseFont: MQPHVJ+GillSansMT-Bold CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: GillSansMT-Bold Flags: Nonsymbolic, ForceBold FontBBox: -177, -319, 1167, 939 FontFile2: true Font: BaseFont: OZDFOI+GillSansMT CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: GillSansMT Flags: Nonsymbolic FontBBox: -162, -282, 1041, 918 FontFile2: true Font: BaseFont: ECEHRU+TimesNewRomanPS-ItalicMT CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: TimesNewRomanPS-ItalicMT Flags: Nonsymbolic, Italic FontBBox: -498, -307, 1333, 1023 FontFile2: true Font: BaseFont: VXCXHL+GillSansMT-Italic CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: GillSansMT-Italic Flags: Nonsymbolic, Italic FontBBox: -201, -280, 1009, 922 FontFile2: true Font: BaseFont: RQHQQN+TimesNewRomanPSMT CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: TimesNewRomanPSMT Flags: Nonsymbolic FontBBox: -568, -307, 2000, 1007 FontFile2: true XMP: uuid:08C5CDE8-5D56-51A3-9178-A167C3A9220C uuid:57AE1E0B-8B1F-57C2-063B-85DE5E8CB3D5 2021-03-04T20:56:28-08:00 2021-03-05T10:29:05+05:30 Arbortext Advanced Print Publisher 11.0.3433/W Unicode 2021-03-05T10:29:05+05:30 PDFlib+PDI 9.0.3p4 (C++/Win32) PStill version 1.84.36 PPA_A_297581 543..548 Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 156, 505, 167, 515 Flags: Print Annotation: Subtype: Link Rect: 167, 509, 171, 519 Flags: Print Destination: 30 Annotation: Subtype: Link Rect: 165, 496, 169, 506 Flags: Print Destination: 30 Annotation: Subtype: Link Rect: 170, 496, 174, 506 Flags: Print Destination: 30 Annotation: Subtype: Link Rect: 149, 479, 160, 489 Flags: Print Annotation: Subtype: Link Rect: 160, 483, 163, 493 Flags: Print Destination: 30 Annotation: Subtype: Link Rect: 165, 483, 168, 493 Flags: Print Destination: 30 Annotation: Subtype: Link Rect: 120, 466, 131, 476 Flags: Print Annotation: Subtype: Link Rect: 131, 470, 135, 480 Flags: Print Destination: 30 Annotation: Subtype: Link Rect: 202, 470, 206, 480 Flags: Print Destination: 30 Annotation: Subtype: Link Rect: 136, 457, 139, 467 Flags: Print Destination: 30 Annotation: Subtype: Link Rect: 191, 457, 195, 467 Flags: Print Destination: 30 Annotation: Subtype: Link Rect: 196, 457, 200, 467 Flags: Print Destination: 30 Annotation: Subtype: Link Rect: 114, 444, 117, 454 Flags: Print Destination: 30 Annotation: Subtype: Link Rect: 183, 444, 187, 454 Flags: Print Destination: 30 Annotation: Subtype: Link Rect: 125, 431, 128, 441 Flags: Print Destination: 30 Annotation: Subtype: Link Rect: 130, 431, 133, 441 Flags: Print Destination: 30 Annotation: Subtype: Link Rect: 171, 431, 175, 441 Flags: Print Destination: 30 Annotation: Subtype: Link Rect: 176, 431, 180, 441 Flags: Print Destination: 30 Annotation: Subtype: Link Rect: 137, 414, 148, 424 Flags: Print Annotation: Subtype: Link Rect: 148, 418, 152, 428 Flags: Print Destination: 30 Annotation: Subtype: Link Rect: 153, 418, 157, 428 Flags: Print Destination: 30 Annotation: Subtype: Link Rect: 158, 418, 165, 428 Flags: Print Destination: 30 Annotation: Subtype: Link Rect: 392, 76, 396, 86 Flags: Print Destination: 352 Annotation: Subtype: Link Rect: 398, 76, 402, 86 Flags: Print Destination: 352 Annotation: Subtype: Link Rect: 90, 72, 164, 80 Flags: Print Annotation: Subtype: Link Rect: 70, 39, 101, 45 Flags: Print Annotation: Subtype: Link Rect: 113, 36, 123, 46 Flags: Print Annotation: Subtype: Link Rect: 129, 37, 140, 46 Flags: Print Annotation: Subtype: Link Rect: 146, 36, 156, 47 Flags: Print Annotation: Subtype: Link Rect: 162, 36, 172, 46 Flags: Print Annotation: Subtype: Link Rect: 219, 31, 260, 45 Flags: Print Annotation: Subtype: Link Rect: 496, 735, 558, 747 Flags: Print Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 279, 718, 290, 728 Flags: Print Destination: 352 Annotation: Subtype: Link Rect: 255, 662, 259, 672 Flags: Print Destination: 352 Annotation: Subtype: Link Rect: 95, 620, 99, 630 Flags: Print Destination: 352 Annotation: Subtype: Link Rect: 90, 494, 94, 504 Flags: Print Destination: 352 Annotation: Subtype: Link Rect: 96, 494, 100, 504 Flags: Print Destination: 352 Annotation: Subtype: Link Rect: 262, 480, 269, 490 Flags: Print Destination: 352 Annotation: Subtype: Link Rect: 88, 452, 95, 462 Flags: Print Destination: 352 Annotation: Subtype: Link Rect: 97, 452, 104, 462 Flags: Print Destination: 228 Annotation: Subtype: Link Rect: 106, 382, 114, 392 Flags: Print Destination: 228 Annotation: Subtype: Link Rect: 194, 172, 201, 182 Flags: Print Destination: 228 Annotation: Subtype: Link Rect: 389, 704, 397, 714 Flags: Print Destination: 228 Annotation: Subtype: Link Rect: 366, 532, 474, 542 Flags: Print Annotation: Subtype: Link Rect: 393, 490, 500, 500 Flags: Print Annotation: Subtype: Link Rect: 506, 494, 524, 504 Flags: Print Destination: 228 Annotation: Subtype: Link Rect: 372, 452, 379, 462 Flags: Print Destination: 228 Annotation: Subtype: Link Rect: 497, 172, 504, 182 Flags: Print Destination: 228 Annotation: Subtype: Link Rect: 90, 24, 120, 30 Flags: Print Annotation: Subtype: Link Rect: 500, 754, 541, 762 Flags: Print Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 491, 25, 522, 31 Flags: Print Annotation: Subtype: Link Rect: 70, 754, 111, 762 Flags: Print Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 171, 588, 202, 598 Flags: Print Destination: 450 Annotation: Subtype: Link Rect: 98, 536, 116, 546 Flags: Print Destination: 228 Annotation: Subtype: Link Rect: 103, 466, 111, 476 Flags: Print Destination: 228 Annotation: Subtype: Link Rect: 339, 732, 346, 742 Flags: Print Destination: 228 Annotation: Subtype: Link Rect: 348, 732, 356, 742 Flags: Print Destination: 228 Annotation: Subtype: Link Rect: 358, 732, 365, 742 Flags: Print Destination: 228 Annotation: Subtype: Link Rect: 484, 634, 492, 644 Flags: Print Destination: 228 Annotation: Subtype: Link Rect: 494, 634, 501, 644 Flags: Print Destination: 228 Annotation: Subtype: Link Rect: 430, 578, 437, 588 Flags: Print Destination: 228 Annotation: Subtype: Link Rect: 439, 578, 447, 588 Flags: Print Destination: 228 Annotation: Subtype: Link Rect: 499, 508, 506, 518 Flags: Print Destination: 228 Annotation: Subtype: Link Rect: 508, 508, 516, 518 Flags: Print Destination: 228 Annotation: Subtype: Link Rect: 358, 424, 365, 434 Flags: Print Destination: 228 Annotation: Subtype: Link Rect: 90, 24, 120, 30 Flags: Print Annotation: Subtype: Link Rect: 500, 754, 541, 762 Flags: Print Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 492, 390, 508, 398 Flags: Print Destination: 30 Annotation: Subtype: Link Rect: 397, 370, 413, 378 Flags: Print Destination: 30 Annotation: Subtype: Link Rect: 465, 370, 556, 378 Flags: Print Annotation: Subtype: Link Rect: 527, 340, 543, 348 Flags: Print Destination: 59 Annotation: Subtype: Link Rect: 347, 330, 436, 338 Flags: Print Annotation: Subtype: Link Rect: 353, 290, 369, 298 Flags: Print Destination: null Annotation: Subtype: Link Rect: 437, 290, 527, 298 Flags: Print Annotation: Subtype: Link Rect: 387, 260, 403, 268 Flags: Print Destination: null Annotation: Subtype: Link Rect: 451, 260, 545, 268 Flags: Print Annotation: Subtype: Link Rect: 532, 230, 548, 238 Flags: Print Destination: null Annotation: Subtype: Link Rect: 379, 220, 469, 228 Flags: Print Annotation: Subtype: Link Rect: 359, 190, 375, 198 Flags: Print Destination: 59 Annotation: Subtype: Link Rect: 447, 190, 531, 198 Flags: Print Annotation: Subtype: Link Rect: 379, 170, 395, 178 Flags: Print Destination: 59 Annotation: Subtype: Link Rect: 414, 170, 461, 178 Flags: Print Annotation: Subtype: Link Rect: 334, 140, 350, 148 Flags: Print Destination: 59 Annotation: Subtype: Link Rect: 429, 140, 536, 148 Flags: Print Annotation: Subtype: Link Rect: 490, 110, 506, 118 Flags: Print Destination: 59 Annotation: Subtype: Link Rect: 347, 100, 441, 108 Flags: Print Annotation: Subtype: Link Rect: 334, 70, 350, 78 Flags: Print Destination: 59 Annotation: Subtype: Link Rect: 418, 70, 509, 78 Flags: Print Annotation: Subtype: Link Rect: 491, 25, 522, 31 Flags: Print Annotation: Subtype: Link Rect: 70, 754, 111, 762 Flags: Print Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 115, 709, 131, 717 Flags: Print Destination: 59 Annotation: Subtype: Link Rect: 199, 709, 290, 717 Flags: Print Annotation: Subtype: Link Rect: 238, 658, 254, 666 Flags: Print Destination: 59 Annotation: Subtype: Link Rect: 80, 648, 170, 656 Flags: Print Annotation: Subtype: Link Rect: 171, 618, 187, 626 Flags: Print Destination: 59 Annotation: Subtype: Link Rect: 263, 618, 290, 626 Flags: Print Annotation: Subtype: Link Rect: 66, 608, 136, 616 Flags: Print Annotation: Subtype: Link Rect: 113, 558, 129, 566 Flags: Print Destination: 59 Annotation: Subtype: Link Rect: 169, 527, 185, 535 Flags: Print Destination: 59 Annotation: Subtype: Link Rect: 66, 507, 82, 515 Flags: Print Destination: null Annotation: Subtype: Link Rect: 121, 467, 137, 475 Flags: Print Destination: null Annotation: Subtype: Link Rect: 210, 467, 290, 475 Flags: Print Annotation: Subtype: Link Rect: 66, 457, 98, 465 Flags: Print Annotation: Subtype: Link Rect: 178, 427, 194, 435 Flags: Print Destination: 450 Annotation: Subtype: Link Rect: 263, 427, 290, 435 Flags: Print Annotation: Subtype: Link Rect: 66, 417, 118, 425 Flags: Print Annotation: Subtype: Link Rect: 453, 719, 469, 727 Flags: Print Destination: null Annotation: Subtype: Link Rect: 514, 719, 541, 727 Flags: Print Annotation: Subtype: Link Rect: 317, 709, 397, 717 Flags: Print Annotation: Subtype: Link Rect: 515, 669, 531, 677 Flags: Print Destination: null Annotation: Subtype: Link Rect: 383, 659, 443, 667 Flags: Print Annotation: Subtype: Link Rect: 477, 639, 493, 647 Flags: Print Destination: 450 Annotation: Subtype: Link Rect: 330, 629, 421, 637 Flags: Print Annotation: Subtype: Link Rect: 513, 619, 529, 627 Flags: Print Destination: 450 Annotation: Subtype: Link Rect: 473, 599, 489, 607 Flags: Print Destination: 450 Annotation: Subtype: Link Rect: 330, 589, 405, 597 Flags: Print Annotation: Subtype: Link Rect: 362, 549, 378, 557 Flags: Print Destination: 450 Annotation: Subtype: Link Rect: 489, 549, 541, 557 Flags: Print Annotation: Subtype: Link Rect: 317, 539, 362, 547 Flags: Print Annotation: Subtype: Link Rect: 481, 519, 497, 527 Flags: Print Destination: 450 Annotation: Subtype: Link Rect: 364, 509, 436, 517 Flags: Print Annotation: Subtype: Link Rect: 473, 479, 489, 487 Flags: Print Destination: 450 Annotation: Subtype: Link Rect: 330, 469, 410, 477 Flags: Print Annotation: Subtype: Link Rect: 418, 439, 434, 447 Flags: Print Destination: 450 Annotation: Subtype: Link Rect: 502, 439, 541, 447 Flags: Print Annotation: Subtype: Link Rect: 317, 429, 339, 437 Flags: Print Annotation: Subtype: Link Rect: 468, 162, 529, 174 Flags: Print Annotation: Subtype: Link Rect: 507, 102, 526, 110 Flags: Print Annotation: Subtype: Link Rect: 304, 94, 426, 102 Flags: Print Annotation: Subtype: Link Rect: 90, 24, 120, 30 Flags: Print Annotation: Subtype: Link Rect: 500, 754, 541, 762 Flags: Print Checksum: 9f1e0900 Type: CRC32 Checksum: abb5ad4c4af0c402ad862c8fa4e8e858 Type: MD5 Checksum: 0b9be094bffa7d754f3496a79035485a06d9635c Type: SHA-1