f2a4734421a1d4d958b5d9419ff58bec pmc_34682518.pdf 36991c3626f091f496797fde43ad69bab2c5abcd pmc_34682518.pdf 769b96bd3cc2201862ea3a48cf408bc5459bb79b4a861fce9530e61fac823ec9 pmc_34682518.pdf Title: Intelligent Coaching Assistant for the Promotion of Healthy Habits in a Multidomain mHealth-Based Intervention forBrain Health Subject: Brain Health is defined as the development and preservation of optimal brain integrity and neural network functioning for a given age. Recent studies have related healthy habits with better maintenance of brain health across the lifespan. As a part of the Barcelona Brain Health Initiative (BBHI), a mHealth platform has been developed with the purpose of helping people to improve and monitor their healthy habits, facilitating the delivery of health coaching strategies. A decision support system (DSS), named Intelligent Coaching Assistant (ICA), has been developed to ease the work of professional brain health coaches, helping them design and monitor adherence to multidomain interventions in a more efficient manner. Personalized recommendations are based on users’ current healthy habits, individual preferences, and motivational aspects. Taking these inputs, an initial user profile is defined, and the ICA applies an algorithm for determining the most suitable personalized intervention plan. An initial validation has been done focusing on assessing the feasibility and usability of the solution, involving 20 participants for three weeks. We conclude that this kind of technology-based intervention is feasible and implementable in real-world settings. Importantly, the personalized intervention proposal generated by the DSS is feasible and its acceptability and usability are high. Keywords: mHealth; brain health; decision support; intervention; monitoring; coaching; healthy lifestyles Author: Diego Moreno-Blanco, Javier Solana-Sánchez, Patricia Sánchez-González, Manuel Jiménez-Hernando, Gabriele Cattaneo, Alba Roca, Joyce Gomes-Osman, Josep María Tormos-Muñoz, David Bartrés-Faz, Álvaro Pascual-Leone and Enrique J. Gómez Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Fri Oct 15 07:30:13 2021 CEST ModDate: Fri Oct 15 07:43:49 2021 CEST Custom Metadata: no Metadata Stream: no Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 19 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 2998347 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- FFAYKL+VnURWPalladioL-Bold Type 1 Custom yes yes no 10 0 ZMKWYH+VnURWPalladioL Type 1 Custom yes yes no 15 0 AWJPXW+URWPalladioL-Ital Type 1 Custom yes yes no 19 0 WLIMUV+URWPalladioL-Bold Type 1 Custom yes yes no 24 0 QNLMMY+URWPalladioL-Roma Type 1 Custom yes yes no 28 0 LWQXII+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 36 0 IRWHZX+TimesNewRomanPSMT Type 1C WinAnsi yes yes no 39 0 MCBCCI+SourceSansRoman-Regular Type 1C Custom yes yes no 61 0 MCBCCM+SourceSansRoman.613wght Type 1C Custom yes yes no 65 0 MCBCCO+SourceSansRoman-Bold Type 1C Custom yes yes no 69 0 VQQJEC+CMSY10 Type 1 Builtin yes yes no 84 0 QQXUPP+PazoMath Type 1 Builtin yes yes no 97 0 RFLZJB+CMR10 Type 1 Builtin yes yes no 101 0 GFJGBP+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 119 0 GFJGCB+PalatinoLinotype TrueType WinAnsi yes yes no 122 0 GFJGCD+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 125 0 GFJHFM+Symbol Type 1C Custom yes yes yes 138 0 GFJGBP+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 143 0 GFJGCB+PalatinoLinotype TrueType WinAnsi yes yes no 146 0 GFJGCD+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 149 0 GFJHFN+Arial CID TrueType Identity-H yes yes yes 152 0 GFJJDD+CambriaMath CID TrueType Identity-H yes yes yes 158 0 GFJGBP+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 168 0 GFJGCA+PalatinoLinotype CID TrueType Identity-H yes yes yes 171 0 GFJGCB+PalatinoLinotype TrueType WinAnsi yes yes no 177 0 GFJGCD+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 180 0 GFJJDD+CambriaMath CID TrueType Identity-H yes yes yes 183 0 GFJGBP+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 199 0 GFJGCB+PalatinoLinotype TrueType WinAnsi yes yes no 202 0 GFJGCD+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 205 0 GFJGBP+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 218 0 GFJGCB+PalatinoLinotype TrueType WinAnsi yes yes no 221 0 GFJGCD+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 224 0 GFJGBP+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 234 0 GFJGCB+PalatinoLinotype TrueType WinAnsi yes yes no 237 0 GFJGCD+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 240 0 GFJGBP+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 257 0 GFJGCB+PalatinoLinotype TrueType WinAnsi yes yes no 260 0 GFJGCD+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 263 0 GFJGBP+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 273 0 GFJGCB+PalatinoLinotype TrueType WinAnsi yes yes no 276 0 GFJGCD+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 279 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-10-02 03:38:40 CEST RepresentationInformation: pmc_34682518.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2023-03-31 12:05:55 CEST Size: 2998347 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 417 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: section.1 Item: Title: Materials and Methods Destination: section.2 Children: Item: Title: Intervention Design and Goals Destination: subsection.2.1 Item: Title: Brain Health Knowledge Pills Destination: subsection.2.2 Item: Title: Algorithm Design Destination: subsection.2.3 Children: Item: Title: Phase I. Number of Pills for Each Domain Destination: subsubsection.2.3.1 Item: Title: Phase II. Pills Selection for Each Pillar Destination: subsubsection.2.3.2 Item: Title: Phase III. Intervention Scheduling Destination: subsubsection.2.3.3 Item: Title: ICA Integration in the mHealth Platform Destination: subsection.2.4 Item: Title: Validation Plan Design Destination: subsection.2.5 Item: Title: Results Destination: section.3 Children: Item: Title: Results of Technical Validation Pilot Destination: subsection.3.1 Item: Title: Results of Feasibility and Usability Pilot Destination: subsection.3.2 Item: Title: Discussion Destination: section.4 Item: Title: References Destination: section.4 Info: Title: Intelligent Coaching Assistant for the Promotion of Healthy Habits in a Multidomain mHealth-Based Intervention forBrain Health Author: Diego Moreno-Blanco, Javier Solana-Sánchez, Patricia Sánchez-González, Manuel Jiménez-Hernando, Gabriele Cattaneo, Alba Roca, Joyce Gomes-Osman, Josep María Tormos-Muñoz, David Bartrés-Faz, Álvaro Pascual-Leone and Enrique J. Gómez Subject: Brain Health is defined as the development and preservation of optimal brain integrity and neural network functioning for a given age. Recent studies have related healthy habits with better maintenance of brain health across the lifespan. As a part of the Barcelona Brain Health Initiative (BBHI), a mHealth platform has been developed with the purpose of helping people to improve and monitor their healthy habits, facilitating the delivery of health coaching strategies. A decision support system (DSS), named Intelligent Coaching Assistant (ICA), has been developed to ease the work of professional brain health coaches, helping them design and monitor adherence to multidomain interventions in a more efficient manner. Personalized recommendations are based on users’ current healthy habits, individual preferences, and motivational aspects. Taking these inputs, an initial user profile is defined, and the ICA applies an algorithm for determining the most suitable personalized intervention plan. An initial validation has been done focusing on assessing the feasibility and usability of the solution, involving 20 participants for three weeks. We conclude that this kind of technology-based intervention is feasible and implementable in real-world settings. Importantly, the personalized intervention proposal generated by the DSS is feasible and its acceptability and usability are high. Keywords: mHealth; brain health; decision support; intervention; monitoring; coaching; healthy lifestyles Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Fri Oct 15 07:30:13 CEST 2021 ModDate: Fri Oct 15 07:43:49 CEST 2021 ID: 0xff040908c2acf60fc9aa9b1e7d18036c, 0xff040908c2acf60fc9aa9b1e7d18036c Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: QQXUPP+PazoMath FontSubset: true FirstChar: 229 LastChar: 229 FontDescriptor: FontName: QQXUPP+PazoMath Flags: Symbolic FontBBox: -40, -283, 878, 946 FontFile: true Font: BaseFont: AWJPXW+URWPalladioL-Ital FontSubset: true FirstChar: 2 LastChar: 150 FontDescriptor: FontName: AWJPXW+URWPalladioL-Ital Flags: Symbolic FontBBox: -170, -305, 1010, 941 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: VQQJEC+CMSY10 FontSubset: true FirstChar: 0 LastChar: 21 FontDescriptor: FontName: VQQJEC+CMSY10 Flags: Symbolic FontBBox: -29, -960, 1116, 775 FontFile: true Font: BaseFont: RFLZJB+CMR10 FontSubset: true FirstChar: 43 LastChar: 61 FontDescriptor: FontName: RFLZJB+CMR10 Flags: Symbolic FontBBox: -40, -250, 1009, 750 FontFile: true Font: BaseFont: WLIMUV+URWPalladioL-Bold FontSubset: true FirstChar: 2 LastChar: 241 FontDescriptor: FontName: WLIMUV+URWPalladioL-Bold Flags: Symbolic FontBBox: -152, -301, 1000, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: FFAYKL+VnURWPalladioL-Bold FontSubset: true FirstChar: 129 LastChar: 226 FontDescriptor: FontName: FFAYKL+VnURWPalladioL-Bold Flags: Symbolic FontBBox: -152, -301, 1000, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: QNLMMY+URWPalladioL-Roma FontSubset: true FirstChar: 2 LastChar: 246 FontDescriptor: FontName: QNLMMY+URWPalladioL-Roma Flags: Symbolic FontBBox: -166, -283, 1021, 943 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: ZMKWYH+VnURWPalladioL FontSubset: true FirstChar: 129 LastChar: 226 FontDescriptor: FontName: ZMKWYH+VnURWPalladioL Flags: Symbolic FontBBox: -166, -283, 1021, 943 FontFile: true EncodingDictionary: Differences: true Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 35, 759, 181, 795 Annotation: Subtype: Link Rect: 515, 759, 560, 795 Annotation: Subtype: Link Rect: 155, 643, 166, 656 Annotation: Subtype: Link Rect: 298, 643, 309, 656 Annotation: Subtype: Link Rect: 446, 643, 457, 656 Annotation: Subtype: Link Rect: 332, 630, 343, 644 Annotation: Subtype: Link Rect: 106, 346, 154, 355 Annotation: Subtype: Link Rect: 35, 334, 139, 343 Annotation: Subtype: Link Rect: 35, 162, 97, 184 Annotation: Subtype: Link Rect: 153, 89, 154, 98 Annotation: Subtype: Link Rect: 35, 77, 147, 86 Annotation: Subtype: Link Rect: 298, 99, 305, 108 ActionDest: 290 Annotation: Subtype: Link Rect: 550, 74, 557, 83 ActionDest: 290 Annotation: Subtype: Link Rect: 205, 17, 354, 28 Annotation: Subtype: Link Rect: 414, 17, 558, 28 Annotation: Subtype: Link Rect: 35, 482, 87, 501 Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 469, 624, 476, 633 ActionDest: 290 Annotation: Subtype: Link Rect: 201, 536, 208, 545 ActionDest: 290 Annotation: Subtype: Link Rect: 462, 498, 469, 507 ActionDest: 290 Annotation: Subtype: Link Rect: 333, 423, 340, 432 ActionDest: 290 Annotation: Subtype: Link Rect: 243, 385, 250, 394 ActionDest: 290 Annotation: Subtype: Link Rect: 215, 335, 222, 344 ActionDest: 290 Annotation: Subtype: Link Rect: 324, 184, 331, 193 ActionDest: 290 Annotation: Subtype: Link Rect: 482, 172, 489, 181 ActionDest: 290 Annotation: Subtype: Link Rect: 541, 159, 553, 168 ActionDest: 290 Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 382, 584, 389, 593 ActionDest: 290 Annotation: Subtype: Link Rect: 544, 421, 556, 430 ActionDest: 290 Annotation: Subtype: Link Rect: 278, 408, 290, 417 ActionDest: 290 Annotation: Subtype: Link Rect: 234, 129, 246, 138 ActionDest: 290 Annotation: Subtype: Link Rect: 247, 129, 258, 138 ActionDest: 290 Annotation: Subtype: Link Rect: 470, 66, 482, 75 ActionDest: 290 Annotation: Subtype: Link Rect: 482, 66, 494, 75 ActionDest: 290 Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 385, 597, 397, 606 ActionDest: 290 Annotation: Subtype: Link Rect: 366, 559, 378, 568 ActionDest: 290 Annotation: Subtype: Link Rect: 544, 521, 556, 530 ActionDest: 290 Annotation: Subtype: Link Rect: 308, 403, 323, 415 ActionDest: 88 Annotation: Subtype: Link Rect: 506, 88, 513, 100 ActionDest: 91 Annotation: Subtype: Link Rect: 460, 66, 467, 75 ActionDest: 290 Annotation: Subtype: Link Rect: 467, 66, 474, 75 ActionDest: 290 Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 401, 299, 408, 311 ActionDest: 105 Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 513, 722, 525, 731 ActionDest: 290 Annotation: Subtype: Link Rect: 534, 385, 541, 397 ActionDest: 132 Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 537, 636, 544, 648 ActionDest: 132 Page: Sequence: 8 Page: Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 212, 732, 219, 744 ActionDest: 190 Annotation: Subtype: Link Rect: 541, 552, 548, 564 ActionDest: 190 Page: Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 256, 694, 263, 706 ActionDest: 193 Annotation: Subtype: Link Rect: 199, 348, 206, 360 ActionDest: 212 Annotation: Subtype: Link Rect: 438, 286, 445, 298 ActionDest: 212 Annotation: Subtype: Link Rect: 524, 225, 531, 234 ActionDest: 290 Annotation: Subtype: Link Rect: 220, 175, 232, 184 ActionDest: 290 Page: Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 209, 441, 216, 452 ActionDest: 193 Annotation: Subtype: Link Rect: 86, 427, 93, 439 ActionDest: 212 Page: Sequence: 12 Annotations: Annotation: Subtype: Link Rect: 236, 402, 243, 414 ActionDest: 245 Annotation: Subtype: Link Rect: 301, 114, 308, 126 ActionDest: 248 Page: Sequence: 13 Annotations: Annotation: Subtype: Link Rect: 213, 486, 220, 498 ActionDest: 248 Annotation: Subtype: Link Rect: 424, 488, 436, 498 ActionDest: 290 Annotation: Subtype: Link Rect: 438, 473, 445, 485 ActionDest: 251 Annotation: Subtype: Link Rect: 421, 451, 433, 460 ActionDest: 290 Annotation: Subtype: Link Rect: 413, 398, 420, 410 ActionDest: 251 Annotation: Subtype: Link Rect: 336, 385, 343, 397 ActionDest: 267 Page: Sequence: 14 Annotations: Annotation: Subtype: Link Rect: 391, 366, 402, 374 ActionDest: 290 Page: Sequence: 15 Annotations: Annotation: Subtype: Link Rect: 472, 146, 484, 155 ActionDest: 290 Page: Sequence: 16 Annotations: Annotation: Subtype: Link Rect: 266, 735, 278, 744 ActionDest: 293 Annotation: Subtype: Link Rect: 375, 735, 387, 744 ActionDest: 293 Annotation: Subtype: Link Rect: 491, 659, 503, 669 ActionDest: 290 Annotation: Subtype: Link Rect: 416, 456, 423, 468 ActionDest: 267 Annotation: Subtype: Link Rect: 299, 396, 306, 405 ActionDest: 248 Annotation: Subtype: Link Rect: 394, 243, 401, 255 ActionDest: 212 Page: Sequence: 17 Page: Sequence: 18 Annotations: Annotation: Subtype: Link Rect: 59, 696, 97, 706 Annotation: Subtype: Link Rect: 376, 672, 414, 683 Annotation: Subtype: Link Rect: 420, 672, 456, 683 Annotation: Subtype: Link Rect: 148, 592, 185, 602 Annotation: Subtype: Link Rect: 191, 592, 227, 602 Annotation: Subtype: Link Rect: 270, 569, 308, 579 Annotation: Subtype: Link Rect: 314, 569, 350, 579 Annotation: Subtype: Link Rect: 468, 534, 505, 545 Annotation: Subtype: Link Rect: 511, 534, 547, 545 Annotation: Subtype: Link Rect: 95, 466, 132, 476 Annotation: Subtype: Link Rect: 139, 466, 175, 476 Annotation: Subtype: Link Rect: 315, 453, 413, 464 Annotation: Subtype: Link Rect: 194, 420, 231, 430 Annotation: Subtype: Link Rect: 238, 420, 274, 430 Annotation: Subtype: Link Rect: 176, 407, 316, 418 Annotation: Subtype: Link Rect: 200, 396, 365, 407 Annotation: Subtype: Link Rect: 366, 373, 404, 384 Annotation: Subtype: Link Rect: 95, 339, 133, 349 Annotation: Subtype: Link Rect: 139, 339, 175, 349 Annotation: Subtype: Link Rect: 263, 304, 301, 315 Annotation: Subtype: Link Rect: 307, 304, 343, 315 Annotation: Subtype: Link Rect: 221, 270, 258, 280 Annotation: Subtype: Link Rect: 264, 270, 301, 280 Annotation: Subtype: Link Rect: 503, 258, 560, 269 Annotation: Subtype: Link Rect: 56, 246, 544, 257 Annotation: Subtype: Link Rect: 254, 178, 291, 188 Annotation: Subtype: Link Rect: 297, 178, 333, 188 Annotation: Subtype: Link Rect: 130, 109, 168, 119 Annotation: Subtype: Link Rect: 174, 109, 210, 119 Page: Sequence: 19 Annotations: Annotation: Subtype: Link Rect: 393, 721, 431, 732 Annotation: Subtype: Link Rect: 437, 721, 473, 732 Annotation: Subtype: Link Rect: 245, 686, 282, 697 Annotation: Subtype: Link Rect: 289, 686, 325, 697 Checksum: 8f1bbd52 Type: CRC32 Checksum: f2a4734421a1d4d958b5d9419ff58bec Type: MD5 Checksum: 36991c3626f091f496797fde43ad69bab2c5abcd Type: SHA-1 Checksum: 769b96bd3cc2201862ea3a48cf408bc5459bb79b4a861fce9530e61fac823ec9 Type: SHA-256