097367e90ac323088b80ba1a5cd9301e  pmc_34755352.pdf
feaa9708548719d88dfe92e30167dd34a7a2f654  pmc_34755352.pdf
d04bfcb43479e750dc370b91de2936eac93a9ba70499ad911b14aa481a67505e  pmc_34755352.pdf

Subject:        Journal of Medical Virology, doi:10.1002/jmv.27446
Keywords:       false negative diagnostic; nasopharyngeal sample transport kits; RNA subunit of ribonuclease P (RNase P) amplification; SARS‐CoV‐2 diagnostics; SARS‐CoV‐2 ORF1ab gene; virus transport medium
Author:         Carlos Barrera‐Avalos
Creator:        John Wiley & Sons
CreationDate:   Sun Nov 14 10:21:26 2021 CET
ModDate:        Sun Nov 14 10:21:26 2021 CET
Tagged:         no
UserProperties: no
Suspects:       no
Form:           AcroForm
JavaScript:     no
Pages:          8
Encrypted:      no
Page size:      595.276 x 782.362 pts
Page rot:       0
File size:      998583 bytes
Optimized:      yes
PDF version:    1.6


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
BFCMIF+AdvTTa9c1b374                 Type 1C           WinAnsi          yes yes no     226  0
BFCMIG+AdvTT6071803a.B               Type 1C           WinAnsi          yes yes no     227  0
BFCMIH+AdvTT6071803a.B+20            Type 1C           Custom           yes yes yes    228  0
BFCMJH+AdvTTa9c1b374+20              Type 1C           Custom           yes yes yes    239  0
BFCMJI+AdvTTa9c1b374+21              Type 1C           WinAnsi          yes yes no     245  0
BFCMJJ+AdvTTeb5f0e55.I               Type 1C           WinAnsi          yes yes no     248  0
BFCOFP+AdvTTeb5f0e55.I+03            Type 1C           Custom           yes yes yes    141  0
BFCOHA+AdvTTa9c1b374+22              Type 1C           Custom           yes yes no     140  0
BFDAGF+AdvTTfac587ca.B               Type 1C           WinAnsi          yes yes no     137  0
BFDGAD+AdvOT8608a8d1+20              Type 1C           Custom           yes yes yes    142  0


Jhove (Rel. 1.22.1, 2019-04-17)
 Date: 2022-03-22 02:37:08 CET
 RepresentationInformation: pmc_34755352.pdf
  ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17)
  LastModified: 2022-01-11 05:16:11 CET
  Size: 998583
  Format: PDF
  Version: 1.6
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  Profile: Linearized PDF, ISO PDF/A-1, Level B
  PDFMetadata: 
   Objects: 266
   FreeObjects: 1
   IncrementalUpdates: 1
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseNone
   Info: 
    Author: Carlos Barrera‐Avalos
    Subject: Journal of Medical Virology, doi:10.1002/jmv.27446
    Keywords: false negative diagnostic; nasopharyngeal sample transport kits; RNA subunit of ribonuclease P (RNase P) amplification; SARS‐䌀漀嘠က㈀ 搀椀愀最渀漀猀琀椀挀猀㬀 匀䄀刀匠က䌀漀嘠က㈀ 伀刀䘀㄀愀戀 最攀渀攀㬀 瘀椀爀甀猀 琀爀愀渀猀瀀漀爀琀 洀攀搀椀甀洩⽍潤䑡瑥⡄㨲〲ㄱㄱ㐱㐵ㄲ㘫〵✳〧
    Creator: John Wiley & Sons
    CreationDate: Sun Nov 14 10:51:26 CET 2021
   ID: 0xe8e2f9f606f2fa829256c573f6a735e7, 0xe006f9459e1db247a096016689d3c093
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 349
      ImageHeight: 64
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 349
      ImageHeight: 64
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 349
      ImageHeight: 64
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1500
      ImageHeight: 1632
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 349
      ImageHeight: 64
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1500
      ImageHeight: 1612
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 349
      ImageHeight: 64
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 349
      ImageHeight: 64
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 349
      ImageHeight: 64
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 349
      ImageHeight: 64
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
   Fonts: 
    Type1: 
     Font: 
      BaseFont: BFCMIF+AdvTTa9c1b374
      FontSubset: true
      FirstChar: 39
      LastChar: 243
      FontDescriptor: 
       FontName: BFCMIF+AdvTTa9c1b374
       Flags: Nonsymbolic
       FontBBox: -41, -182, 1020, 937
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: BFCMIG+AdvTT6071803a.B
      FontSubset: true
      FirstChar: 44
      LastChar: 243
      FontDescriptor: 
       FontName: BFCMIG+AdvTT6071803a.B
       Flags: Nonsymbolic
       FontBBox: -60, -180, 1042, 949
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: BFCMIH+AdvTT6071803a.B+20
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: BFCMIH+AdvTT6071803a.B+20
       Flags: Symbolic
       FontBBox: -256, -229, 1223, 947
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: BFCMJI+AdvTTa9c1b374+21
      FontSubset: true
      FirstChar: 153
      LastChar: 153
      FontDescriptor: 
       FontName: BFCMJI+AdvTTa9c1b374+21
       Flags: Nonsymbolic
       FontBBox: 1, -170, 1105, 774
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: BFCMJJ+AdvTTeb5f0e55.I
      FontSubset: true
      FirstChar: 66
      LastChar: 122
      FontDescriptor: 
       FontName: BFCMJJ+AdvTTeb5f0e55.I
       Flags: Nonsymbolic
       FontBBox: -88, -181, 991, 937
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: BFDAGF+AdvTTfac587ca.B
      FontSubset: true
      FirstChar: 49
      LastChar: 85
      FontDescriptor: 
       FontName: BFDAGF+AdvTTfac587ca.B
       Flags: Nonsymbolic
       FontBBox: -77, -178, 1063, 958
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: BFCOHA+AdvTTa9c1b374+22
      FontSubset: true
      FirstChar: 21
      LastChar: 21
      FontDescriptor: 
       FontName: BFCOHA+AdvTTa9c1b374+22
       Flags: Nonsymbolic
       FontBBox: -6, -174, 682, 856
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: BFCOFP+AdvTTeb5f0e55.I+03
      FontSubset: true
      FirstChar: 1
      LastChar: 3
      FontDescriptor: 
       FontName: BFCOFP+AdvTTeb5f0e55.I+03
       Flags: Symbolic
       FontBBox: -395, -268, 1027, 947
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: BFDGAD+AdvOT8608a8d1+20
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: BFDGAD+AdvOT8608a8d1+20
       Flags: Symbolic
       FontBBox: -970, -341, 2000, 1023
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: BFCMJH+AdvTTa9c1b374+20
      FontSubset: true
      FirstChar: 1
      LastChar: 144
      FontDescriptor: 
       FontName: BFCMJH+AdvTTa9c1b374+20
       Flags: Symbolic
       FontBBox: -245, -218, 1168, 943
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="Adobe XMP Core 5.2-c001 63.139439, 2010/09/27-13:37:26        ">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about=""
            xmlns:dc="http://purl.org/dc/elements/1.1/">
         <dc:format>application/pdf</dc:format>
         <dc:identifier>doi:10.1002/jmv.27446</dc:identifier>
         <dc:title>
            <rdf:Alt/>
         </dc:title>
         <dc:creator>
            <rdf:Seq>
               <rdf:li>Carlos Barrera‐Avalos</rdf:li>
               <rdf:li>Roberto Luraschi</rdf:li>
               <rdf:li>Eva Vallejos‐Vidal</rdf:li>
               <rdf:li>Maximiliano Figueroa</rdf:li>
               <rdf:li>Esteban Arenillas</rdf:li>
               <rdf:li>Daniela Barría</rdf:li>
               <rdf:li>Felipe Hernández</rdf:li>
               <rdf:li>Carlos Mateluna</rdf:li>
               <rdf:li>Javier Mena</rdf:li>
               <rdf:li>Claudia Rioseco</rdf:li>
               <rdf:li>Claudia Torrent</rdf:li>
               <rdf:li>Claudio Vergara</rdf:li>
               <rdf:li>Gaby Gutiérrez</rdf:li>
               <rdf:li>Javiera Quiroz</rdf:li>
               <rdf:li>Javiera Alarcón</rdf:li>
               <rdf:li>Julio Cartagena</rdf:li>
               <rdf:li>Javiera Cayunao</rdf:li>
               <rdf:li>Andrea Mella‐Torres</rdf:li>
               <rdf:li>Álvaro Santibañez</rdf:li>
               <rdf:li>Sebastián Tapia</rdf:li>
               <rdf:li>Alejandro Undurraga</rdf:li>
               <rdf:li>Deborah Vargas</rdf:li>
               <rdf:li>Valentina Wong</rdf:li>
               <rdf:li>Ailen Inostroza‐Molina</rdf:li>
               <rdf:li>Daniel Valdés</rdf:li>
               <rdf:li>Mónica Imarai</rdf:li>
               <rdf:li>Claudio Acuña‐Castillo</rdf:li>
               <rdf:li>Felipe E. Reyes‐López</rdf:li>
               <rdf:li/>
               <rdf:li>Ana M. Sandino</rdf:li>
               <rdf:li/>
            </rdf:Seq>
         </dc:creator>
         <dc:publisher>
            <rdf:Bag>
               <rdf:li>John Wiley &amp; Sons, Ltd</rdf:li>
            </rdf:Bag>
         </dc:publisher>
         <dc:subject>
            <rdf:Bag>
               <rdf:li>false negative diagnostic</rdf:li>
               <rdf:li>nasopharyngeal sample transport kits</rdf:li>
               <rdf:li>RNA subunit of ribonuclease P (RNase P) amplification</rdf:li>
               <rdf:li>SARS‐CoV‐2 diagnostics</rdf:li>
               <rdf:li>SARS‐CoV‐2 ORF1ab gene</rdf:li>
               <rdf:li>virus transport medium</rdf:li>
            </rdf:Bag>
         </dc:subject>
         <dc:description>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Journal of Medical Virology, doi:10.1002/jmv.27446</rdf:li>
            </rdf:Alt>
         </dc:description>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:prism="http://prismstandard.org/namespaces/basic/3.0/">
         <prism:doi>10.1002/jmv.27446</prism:doi>
         <prism:url>http://dx.doi.org/10.1002/jmv.27446</prism:url>
         <prism:aggregationType>journal</prism:aggregationType>
         <prism:publicationName>Journal of Medical Virology</prism:publicationName>
         <prism:copyright/>
         <prism:issn>0146-6615</prism:issn>
         <prism:volume/>
         <prism:number/>
         <prism:pageRange/>
         <prism:startingPage/>
         <prism:endingPage/>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:jav="http://www.niso.org/schemas/jav/1.0/">
         <jav:journal_article_version>VoR</jav:journal_article_version>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmp="http://ns.adobe.com/xap/1.0/">
         <xmp:CreatorTool>John Wiley &amp; Sons</xmp:CreatorTool>
         <xmp:ModifyDate>2021-11-14T14:51:26+05:30</xmp:ModifyDate>
         <xmp:CreateDate>2021-11-14T14:51:26+05:30</xmp:CreateDate>
         <xmp:MetadataDate>2021-11-14T14:51:26+05:30</xmp:MetadataDate>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmpRights="http://ns.adobe.com/xap/1.0/rights/">
         <xmpRights:Marked>True</xmpRights:Marked>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdf="http://ns.adobe.com/pdf/1.3/">
         <pdf:Keywords>false negative diagnostic; nasopharyngeal sample transport kits; RNA subunit of ribonuclease P (RNase P) amplification; SARS‐CoV‐2 diagnostics; SARS‐CoV‐2 ORF1ab gene; virus transport medium</pdf:Keywords>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdfx="http://ns.adobe.com/pdfx/1.3/">
         <pdfx:WPS-ARTICLEDOI>10.1002/jmv.27446</pdfx:WPS-ARTICLEDOI>
         <pdfx:WPS-JOURNALDOI>10.1002/(ISSN)1096-9071</pdfx:WPS-JOURNALDOI>
         <pdfx:WPS-PROCLEVEL>3</pdfx:WPS-PROCLEVEL>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/">
         <xmpMM:DocumentID>uuid:1adebe1f-8178-4db4-b128-4dfdb57ed2df</xmpMM:DocumentID>
         <xmpMM:InstanceID>uuid:f33667e0-436d-454d-a014-8f028fb18ba1</xmpMM:InstanceID>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Label: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 66, 238, 135, 245
      Annotation: 
       Subtype: Link
       Rect: 45, 228, 112, 235
     Thumb: true
    Page: 
     Label: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 153, 516, 161, 524
       Destination: 75
      Annotation: 
       Subtype: Link
       Rect: 61, 477, 70, 485
       Destination: 75
      Annotation: 
       Subtype: Link
       Rect: 183, 451, 186, 459
       Destination: 75
      Annotation: 
       Subtype: Link
       Rect: 72, 399, 75, 407
       Destination: 75
      Annotation: 
       Subtype: Link
       Rect: 498, 581, 502, 589
       Destination: 75
     Thumb: true
    Page: 
     Label: 3
     Thumb: true
    Page: 
     Label: 4
     Thumb: true
    Page: 
     Label: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 140, 578, 150, 586
       Destination: 13
      Annotation: 
       Subtype: Link
       Rect: 71, 552, 81, 560
       Destination: 13
      Annotation: 
       Subtype: Link
       Rect: 259, 513, 269, 521
       Destination: 13
      Annotation: 
       Subtype: Link
       Rect: 72, 461, 82, 469
       Destination: 13
      Annotation: 
       Subtype: Link
       Rect: 72, 383, 81, 391
       Destination: 13
      Annotation: 
       Subtype: Link
       Rect: 231, 331, 241, 339
       Destination: 13
      Annotation: 
       Subtype: Link
       Rect: 140, 266, 150, 274
       Destination: 28
      Annotation: 
       Subtype: Link
       Rect: 152, 240, 162, 248
       Destination: 28
      Annotation: 
       Subtype: Link
       Rect: 274, 123, 284, 131
       Destination: 28
      Annotation: 
       Subtype: Link
       Rect: 524, 721, 533, 729
       Destination: 28
      Annotation: 
       Subtype: Link
       Rect: 398, 594, 402, 602
       Destination: 75
      Annotation: 
       Subtype: Link
       Rect: 321, 425, 335, 433
       Destination: 75
      Annotation: 
       Subtype: Link
       Rect: 419, 425, 437, 433
       Destination: 75
      Annotation: 
       Subtype: Link
       Rect: 459, 412, 466, 420
       Destination: 75
      Annotation: 
       Subtype: Link
       Rect: 449, 87, 466, 95
       Destination: 75
      Annotation: 
       Subtype: Link
       Rect: 361, 74, 368, 82
       Destination: 75
     Thumb: true
    Page: 
     Label: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 206, 724, 213, 732
       Destination: 75
      Annotation: 
       Subtype: Link
       Rect: 238, 581, 245, 589
       Destination: 75
      Annotation: 
       Subtype: Link
       Rect: 131, 555, 146, 563
       Destination: 75
      Annotation: 
       Subtype: Link
       Rect: 184, 542, 208, 550
       Destination: 75
      Annotation: 
       Subtype: Link
       Rect: 63, 529, 70, 537
       Destination: 75
      Annotation: 
       Subtype: Link
       Rect: 117, 412, 133, 420
       Destination: 75
      Annotation: 
       Subtype: Link
       Rect: 107, 399, 114, 407
       Destination: 75
      Annotation: 
       Subtype: Link
       Rect: 281, 399, 288, 407
       Destination: 121
      Annotation: 
       Subtype: Link
       Rect: 83, 256, 98, 264
       Destination: 121
     Thumb: true
    Page: 
     Label: 7
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 104, 388, 206, 396
      Annotation: 
       Subtype: Link
       Rect: 175, 356, 288, 364
      Annotation: 
       Subtype: Link
       Rect: 96, 324, 217, 332
      Annotation: 
       Subtype: Link
       Rect: 105, 292, 203, 299
      Annotation: 
       Subtype: Link
       Rect: 152, 249, 288, 257
      Annotation: 
       Subtype: Link
       Rect: 63, 239, 207, 246
      Annotation: 
       Subtype: Link
       Rect: 63, 196, 221, 203
      Annotation: 
       Subtype: Link
       Rect: 230, 164, 288, 172
      Annotation: 
       Subtype: Link
       Rect: 63, 154, 285, 161
      Annotation: 
       Subtype: Link
       Rect: 98, 122, 257, 129
      Annotation: 
       Subtype: Link
       Rect: 176, 90, 255, 97
      Annotation: 
       Subtype: Link
       Rect: 241, 58, 288, 66
      Annotation: 
       Subtype: Link
       Rect: 63, 48, 138, 55
      Annotation: 
       Subtype: Link
       Rect: 412, 690, 506, 697
      Annotation: 
       Subtype: Link
       Rect: 368, 648, 450, 655
      Annotation: 
       Subtype: Link
       Rect: 450, 616, 549, 623
      Annotation: 
       Subtype: Link
       Rect: 340, 584, 455, 592
      Annotation: 
       Subtype: Link
       Rect: 526, 543, 549, 550
      Annotation: 
       Subtype: Link
       Rect: 325, 532, 398, 540
      Annotation: 
       Subtype: Link
       Rect: 345, 490, 433, 497
      Annotation: 
       Subtype: Link
       Rect: 425, 458, 532, 466
      Annotation: 
       Subtype: Link
       Rect: 370, 416, 475, 424
      Annotation: 
       Subtype: Link
       Rect: 325, 385, 443, 392
      Annotation: 
       Subtype: Link
       Rect: 400, 353, 527, 361
      Annotation: 
       Subtype: Link
       Rect: 527, 332, 549, 340
      Annotation: 
       Subtype: Link
       Rect: 325, 322, 390, 330
      Annotation: 
       Subtype: Link
       Rect: 325, 291, 443, 298
      Annotation: 
       Subtype: Link
       Rect: 527, 269, 549, 277
      Annotation: 
       Subtype: Link
       Rect: 325, 259, 428, 266
      Annotation: 
       Subtype: Link
       Rect: 506, 206, 549, 214
      Annotation: 
       Subtype: Link
       Rect: 325, 196, 391, 203
      Annotation: 
       Subtype: Link
       Rect: 466, 164, 549, 172
      Annotation: 
       Subtype: Link
       Rect: 325, 154, 359, 161
      Annotation: 
       Subtype: Link
       Rect: 421, 112, 537, 119
      Annotation: 
       Subtype: Link
       Rect: 396, 70, 509, 77
     Thumb: true
    Page: 
     Label: 8
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 228, 710, 288, 718
      Annotation: 
       Subtype: Link
       Rect: 63, 700, 97, 707
      Annotation: 
       Subtype: Link
       Rect: 245, 668, 288, 676
      Annotation: 
       Subtype: Link
       Rect: 63, 658, 113, 665
      Annotation: 
       Subtype: Link
       Rect: 63, 626, 167, 634
      Annotation: 
       Subtype: Link
       Rect: 63, 584, 176, 592
      Annotation: 
       Subtype: Link
       Rect: 377, 601, 461, 609
     Thumb: true
  Checksum: f05b4da3
   Type: CRC32
  Checksum: 097367e90ac323088b80ba1a5cd9301e
   Type: MD5
  Checksum: feaa9708548719d88dfe92e30167dd34a7a2f654
   Type: SHA-1