71b07814c86d4d1845291b0ef5f8f00a pmc_34830495.pdf 09e1da96d6be4743f08d4db7456a9b6538b68194 pmc_34830495.pdf 240a0a7384ab9ac3282e62757315f9cecee517dc67f56ba4dc273a64022a1e2c pmc_34830495.pdf Title: COVID-19 Clinical Profile in Latin American Migrants Living in Spain: Does the Geographical Origin Matter? Subject: The aim of this study was to describe and compare the clinical characteristics of hospitalized patients with COVID-19 pneumonia according to their geographical origin. This is a retrospective case-control study of hospitalized patients with confirmed COVID-19 pneumonia treated at Vall d’Hebron University Hospital (Barcelona) during the first wave of the pandemic. Cases were defined as patients born in Latin America and controls were randomly selected among Spanish patients matched by age and gender. Demographic and clinical variables were collected, including comorbidities, symptoms, vital signs and analytical parameters, intensive care unit admission and outcome at 28 days after admission. Overall, 1080 hospitalized patients were registered: 774 (71.6%) from Spain, 142 (13.1%) from Latin America and the rest from other countries. Patients from Latin America were considered as cases and 558 Spanish patients were randomly selected as controls. Latin American patients had a higher proportion of anosmia, rhinorrhea and odynophagia, as well as higher mean levels of platelets and lower mean levels of ferritin than Spanish patients. No differences were found in oxygen requirement and mortality at 28 days after admission, but there was a higher proportion of ICU admissions (28.2% vs. 20.2%, p = 0.0310). An increased proportion of ICU admissions were found in patients from Latin America compared with native Spanish patients when adjusted by age and gender, with no significant differences in in-hospital mortality. Keywords: COVID-19; SARS-CoV-2; Latin America; severity Author: Abiu Sempere, Fernando Salvador, Arnau Monforte, Júlia Sampol, Juan Espinosa-Pereiro, Marta Miarons, Pau Bosch-Nicolau, Alfredo Guillén-del-Castillo, Maria Luisa Aznar, Isabel Campos-Varela, Adrián Sánchez-Montalvá, Lina María Leguízamo-Martínez, Inés Oliveira, Andrés Antón and Benito Almirante Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Tue Nov 9 03:58:56 2021 CET ModDate: Tue Nov 9 04:05:09 2021 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 9 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 276883 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- SFTHCF+VnURWPalladioL Type 1 Custom yes yes no 10 0 ZGUGWQ+URWPalladioL-Ital Type 1 Custom yes yes no 15 0 NIJBFQ+URWPalladioL-Bold Type 1 Custom yes yes no 20 0 XHSUZA+URWPalladioL-Roma Type 1 Custom yes yes no 24 0 DGBDNV+VnURWPalladioL-Bold Type 1 Custom yes yes no 28 0 XPUSBJ+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 36 0 BSDWLC+TimesNewRomanPSMT Type 1C WinAnsi yes yes no 39 0 MCBCCI+SourceSansRoman-Regular Type 1C Custom yes yes no 61 0 MCBCCM+SourceSansRoman.613wght Type 1C Custom yes yes no 65 0 MCBCCO+SourceSansRoman-Bold Type 1C Custom yes yes no 69 0 HCPSKZ+CMSY10 Type 1 Builtin yes yes no 81 0 QLBIEB+URWPalladioL-BoldItal Type 1 Custom yes yes no 88 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2022-03-22 02:33:03 CET RepresentationInformation: pmc_34830495.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2022-01-10 08:11:24 CET Size: 276883 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 248 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7b69c6ba Item: Title: Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@46daef40 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@12f41634 Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@13c27452 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@262b2c86 Info: Title: COVID-19 Clinical Profile in Latin American Migrants Living in Spain: Does the Geographical Origin Matter? Author: Abiu Sempere, Fernando Salvador, Arnau Monforte, Júlia Sampol, Juan Espinosa-Pereiro, Marta Miarons, Pau Bosch-Nicolau, Alfredo Guillén-del-Castillo, Maria Luisa Aznar, Isabel Campos-Varela, Adrián Sánchez-Montalvá, Lina María Leguízamo-Martínez, Inés Oliveira, Andrés Antón and Benito Almirante Subject: The aim of this study was to describe and compare the clinical characteristics of hospitalized patients with COVID-19 pneumonia according to their geographical origin. This is a retrospective case-control study of hospitalized patients with confirmed COVID-19 pneumonia treated at Vall d’Hebron University Hospital (Barcelona) during the first wave of the pandemic. Cases were defined as patients born in Latin America and controls were randomly selected among Spanish patients matched by age and gender. Demographic and clinical variables were collected, including comorbidities, symptoms, vital signs and analytical parameters, intensive care unit admission and outcome at 28 days after admission. Overall, 1080 hospitalized patients were registered: 774 (71.6%) from Spain, 142 (13.1%) from Latin America and the rest from other countries. Patients from Latin America were considered as cases and 558 Spanish patients were randomly selected as controls. Latin American patients had a higher proportion of anosmia, rhinorrhea and odynophagia, as well as higher mean levels of platelets and lower mean levels of ferritin than Spanish patients. No differences were found in oxygen requirement and mortality at 28 days after admission, but there was a higher proportion of ICU admissions (28.2% vs. 20.2%, p = 0.0310). An increased proportion of ICU admissions were found in patients from Latin America compared with native Spanish patients when adjusted by age and gender, with no significant differences in in-hospital mortality. 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