a2a4f283cf80593c70fe721ac03d36fd pmc_34861974.pdf 0044d77e5a400eb9ff8e72a3b587b00757eac85e pmc_34861974.pdf 4348c4bef999849045ccb53f27adecd2853bd4a009d6c0e23e39cda44713bfbf pmc_34861974.pdf Title: Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors Author: Niamh Mullins, JooEun Kang, Adrian I. Campos, Jonathan R.I. Coleman, Alexis C. Edwards, Hanga Galfalvy, Daniel F. Levey, Adriana Lori, Andrey Shabalin, Anna Starnawska, Mei-Hsin Su, Hunna J. Watson, Mark Adams, Swapnil Awasthi, Michael Gandal, Jonathan D. Hafferty, Akitoyo Hishimoto, Minsoo Kim, Satoshi Okazaki, Ikuo Otsuka, Stephan Ripke, Erin B. Ware, Andrew W. Bergen, Wade H. Berrettini, Martin Bohus, Harry Brandt, Xiao Chang, Wei J. Chen, Hsi-Chung Chen, Steven Crawford, Scott Crow, Emily DiBlasi, Philibert Duriez, Fernando Fernández-Aranda, Manfred M. Fichter, Steven Gallinger, Stephen J. Glatt, Philip Gorwood, Yiran Guo, Hakon Hakonarson, Katherine A. Halmi, Hai-Gwo Hwu, Sonia Jain, Stéphane Jamain, Susana Jiménez-Murcia, Craig Johnson, Allan S. Kaplan, Walter H. Kaye, Pamela K. Keel, James L. Kennedy, Kelly L. Klump, Dong Li, Shih-Cheng Liao, Klaus Lieb, Lisa Lilenfeld, Chih-Min Liu, Pierre J. Magistretti, Christian R. Marshall, James E. Mitchell, Eric T. Monson, Richard M. Myers, Dalila Pinto, Abigail Powers, Nicolas Ramoz, Stefan Roepke, Vsevolod Rozanov, Stephen W. Scherer, Christian Schmahl, Marcus Sokolowski, Michael Strober, Laura M. Thornton, Janet Treasure, Ming T. Tsuang, Stephanie H. Witt, D. Blake Woodside, Zeynep Yilmaz, Lea Zillich, Rolf Adolfsson, Ingrid Agartz, Tracy M. Air, Martin Alda, Lars Alfredsson, Ole A. Andreassen, Adebayo Anjorin, Vivek Appadurai, María Soler Artigas, Sandra Van der Auwera, M. Helena Azevedo, Nicholas Bass, Claiton H.D. Bau, Bernhard T. Baune, Frank Bellivier, Klaus Berger, Joanna M. Biernacka, Tim B. Bigdeli, Elisabeth B. Binder, Michael Boehnke, Marco P. Boks, Rosa Bosch, David L. Braff, Richard Bryant, Monika Budde, Enda M. Byrne, Wiepke Cahn, Miguel Casas, Enrique Castelao, Jorge A. Cervilla, Boris Chaumette, Sven Cichon, Aiden Corvin, Nicholas Craddock, David Craig, Franziska Degenhardt, Srdjan Djurovic, Howard J. Edenberg, Ayman H. Fanous, Jerome C. Foo, Andreas J. Forstner, Mark Frye, Janice M. Fullerton, Justine M. Gatt, Pablo V. Gejman, Ina Giegling, Hans J. Grabe, Melissa J. Green, Eugenio H. Grevet, Maria Grigoroiu-Serbanescu, Blanca Gutierrez, Jose Guzman-Parra, Steven P. Hamilton, Marian L. Hamshere, Annette Hartmann, Joanna Hauser, Stefanie Heilmann-Heimbach, Per Hoffmann, Marcus Ising, Ian Jones, Lisa A. Jones, Lina Jonsson, René S. Kahn, John R. Kelsoe, Kenneth S. Kendler, Stefan Kloiber, Karestan C. Koenen, Manolis Kogevinas, Bettina Konte, Marie-Odile Krebs, Mikael Landén, Jacob Lawrence, Marion Leboyer, Phil H. Lee, Douglas F. Levinson, Calwing Liao, Jolanta Lissowska, Susanne Lucae, Fermin Mayoral, Susan L. McElroy, Patrick McGrath, Peter McGuffin, Andrew McQuillin, Sarah E. Medland, Divya Mehta, Ingrid Melle, Yuri Milaneschi, Philip B. Mitchell, Esther Molina, Gunnar Morken, Preben Bo Mortensen, Bertram Müller-Myhsok, Caroline Nievergelt, Vishwajit Nimgaonkar, Markus M. Nöthen, Michael C. O’Donovan, Roel A. Ophoff, Michael J. Owen, Carlos Pato, Michele T. Pato, Brenda W.J.H. Penninx, Jonathan Pimm, Giorgio Pistis, James B. Potash, Robert A. Power, Martin Preisig, Digby Quested, Josep Antoni Ramos-Quiroga, Andreas Reif, Marta Ribasés, Vanesa Richarte, Marcella Rietschel, Margarita Rivera, Andrea Roberts, Gloria Roberts, Guy A. Rouleau, Diego L. Rovaris, Dan Rujescu, Cristina Sánchez-Mora, Alan R. Sanders, Peter R. Schofield, Thomas G. Schulze, Laura J. Scott, Alessandro Serretti, Jianxin Shi, Stanley I. Shyn, Lea Sirignano, Pamela Sklar, Olav B. Smeland, Jordan W. Smoller, Edmund J.S. Sonuga-Barke, Gianfranco Spalletta, John S. Strauss, Beata Świątkowska, Maciej Trzaskowski, Gustavo Turecki, Laura Vilar-Ribó, John B. Vincent, Henry Völzke, James T.R. Walters, Cynthia Shannon Weickert, Thomas W. Weickert, Myrna M. Weissman, Leanne M. Williams, Naomi R. Wray, Clement C. Zai, Allison E. Ashley-Koch, Jean C. Beckham, Elizabeth R. Hauser, Michael A. Hauser, Nathan A. Kimbrel, Jennifer H. Lindquist, Benjamin McMahon, David W. Oslin, Xuejun Qin, , Esben Agerbo, Anders D. Børglum, Gerome Breen, Annette Erlangsen, Tõnu Esko, Joel Gelernter, David M. Hougaard, Ronald C. Kessler, Henry R. Kranzler, Qingqin S. Li, Nicholas G. Martin, Andrew M. McIntosh, Ole Mors, Merete Nordentoft, Catherine M. Olsen, David Porteous, Robert J. Ursano, Danuta Wasserman, Thomas Werge, David C. Whiteman, Cynthia M. Bulik, Hilary Coon, Ditte Demontis, Anna R. Docherty, Po-Hsiu Kuo, Cathryn M. Lewis, J. John Mann, Miguel E. Rentería, Daniel J. Smith, Eli A. Stahl, Murray B. Stein, Fabian Streit, Virginia Willour, Douglas M. RuderferMajor Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Eating Disorders Working Group of the Psychiatric Genomics Consortium, German Borderline Genomics Consortium, MVP Suicide Exemplar Workgroup, VA Million Veteran Program Creator: AH Formatter V7.2 MR1 for Linux64 : 7.2.2.53984 (2021-10-18T16:29+09) Producer: Antenna House PDF Output Library 7.2.1712 CreationDate: Thu Feb 17 17:05:03 2022 CET ModDate: Thu Feb 17 17:05:03 2022 CET Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 33 Encrypted: no Page size: 612 x 792 pts (letter) Page rot: 0 File size: 914164 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- Helvetica-Bold Type 1 Standard no no no 11 0 Helvetica-Oblique Type 1 Standard no no no 13 0 Times-Roman Type 1 Custom no no yes 18 0 Helvetica Type 1 Custom no no yes 48 0 BRCMKC+Code2000 CID TrueType Identity-H yes yes yes 140 0 BRCMKC+STIX-Regular Type 1C Custom yes yes yes 152 0 BRCMKC+STIX-Regular Type 1C Custom yes yes yes 153 0 Times-Bold Type 1 Standard no no no 1393 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-10-21 02:40:40 CEST RepresentationInformation: pmc_34861974.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-03-31 12:06:26 CEST Size: 914164 Format: PDF Version: 1.5 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 0 FreeObjects: 317 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Abstract Item: Title: METHODS AND MATERIALS Children: Item: Title: Cohorts and Case Definition Item: Title: Control Definition Item: Title: Genotyping, Quality Control, and Imputation Item: Title: GWASs and Meta-analysis Item: Title: Statistical Conditioning on Psychiatric Disorders Item: Title: LD Score Regression Item: Title: Polygenic Risk Scoring Item: Title: RESULTS Children: Item: Title: SA Shows Significant SNP-Heritability and PRS Associations Item: Title: GWAS of SA Identifies Locus With Stronger Effect on SA Than Psychiatric Disorders Item: Title: Evidence for Substantial Proportion of SNP-Heritability of SA Not Mediated by Psychiatric Disorders Item: Title: Significant Genetic Overlap Between SA and Psychiatric Traits or Disorders Item: Title: Substantial Shared Genetic Architecture of SA and Nonpsychiatric Risk Factors Not Mediated by MDD Item: Title: DISCUSSION Item: Title: Appendix Item: Title: References Item: Title: Figure 1. Item: Title: Figure 2. Item: Title: Figure 3. Item: Title: Table 1. Item: Title: Table T2 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 152 ImageHeight: 152 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1231 ImageHeight: 1500 BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1500 ImageHeight: 616 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1500 ImageHeight: 631 BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type0: Font: BaseFont: BRCMKC+Code2000 Encoding: Identity-H ToUnicode: true Type1: Font: BaseFont: Helvetica FirstChar: 32 LastChar: 138 FontDescriptor: FontName: Helvetica Flags: Nonsymbolic FontBBox: -166, -225, 1000, 931 EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: Times-Bold Font: BaseFont: Times-Roman FirstChar: 32 LastChar: 155 FontDescriptor: FontName: Times-Roman Flags: Nonsymbolic FontBBox: -168, -218, 1000, 898 EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: BRCMKC+STIX-Regular FontSubset: true FirstChar: 50 LastChar: 128 FontDescriptor: FontName: BRCMKC+STIX-Regular Flags: Nonsymbolic FontBBox: -970, -486, 2208, 1023 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: BRCMKC+STIX-Regular FontSubset: true FirstChar: 129 LastChar: 131 FontDescriptor: FontName: BRCMKC+STIX-Regular Flags: Nonsymbolic FontBBox: -970, -486, 2208, 1023 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: Helvetica-Bold Font: BaseFont: Helvetica-Oblique CIDFontType2: Font: BaseFont: BRCMKC+Code2000 CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: BRCMKC+Code2000 Flags: Symbolic FontBBox: -1111, -295, 2107, 977 FontFile2: true XMP: 2022-02-17T11:05:03-05:00 2022-02-17T11:05:03-05:00 application/pdf Antenna House PDF Output Library 7.2.1712 AH Formatter V7.2 MR1 for Linux64 : 7.2.2.53984 (2021-10-18T16:29+09) 2022-02-17T11:05:03-05:00 Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors Niamh Mullins, JooEun Kang, Adrian I. Campos, Jonathan R.I. Coleman, Alexis C. Edwards, Hanga Galfalvy, Daniel F. Levey, Adriana Lori, Andrey Shabalin, Anna Starnawska, Mei-Hsin Su, Hunna J. Watson, Mark Adams, Swapnil Awasthi, Michael Gandal, Jonathan D. Hafferty, Akitoyo Hishimoto, Minsoo Kim, Satoshi Okazaki, Ikuo Otsuka, Stephan Ripke, Erin B. Ware, Andrew W. Bergen, Wade H. Berrettini, Martin Bohus, Harry Brandt, Xiao Chang, Wei J. Chen, Hsi-Chung Chen, Steven Crawford, Scott Crow, Emily DiBlasi, Philibert Duriez, Fernando Fernández-Aranda, Manfred M. Fichter, Steven Gallinger, Stephen J. Glatt, Philip Gorwood, Yiran Guo, Hakon Hakonarson, Katherine A. Halmi, Hai-Gwo Hwu, Sonia Jain, Stéphane Jamain, Susana Jiménez-Murcia, Craig Johnson, Allan S. Kaplan, Walter H. Kaye, Pamela K. Keel, James L. Kennedy, Kelly L. Klump, Dong Li, Shih-Cheng Liao, Klaus Lieb, Lisa Lilenfeld, Chih-Min Liu, Pierre J. Magistretti, Christian R. Marshall, James E. Mitchell, Eric T. Monson, Richard M. Myers, Dalila Pinto, Abigail Powers, Nicolas Ramoz, Stefan Roepke, Vsevolod Rozanov, Stephen W. Scherer, Christian Schmahl, Marcus Sokolowski, Michael Strober, Laura M. Thornton, Janet Treasure, Ming T. Tsuang, Stephanie H. Witt, D. Blake Woodside, Zeynep Yilmaz, Lea Zillich, Rolf Adolfsson, Ingrid Agartz, Tracy M. Air, Martin Alda, Lars Alfredsson, Ole A. Andreassen, Adebayo Anjorin, Vivek Appadurai, María Soler Artigas, Sandra Van der Auwera, M. Helena Azevedo, Nicholas Bass, Claiton H.D. Bau, Bernhard T. Baune, Frank Bellivier, Klaus Berger, Joanna M. Biernacka, Tim B. Bigdeli, Elisabeth B. Binder, Michael Boehnke, Marco P. Boks, Rosa Bosch, David L. Braff, Richard Bryant, Monika Budde, Enda M. Byrne, Wiepke Cahn, Miguel Casas, Enrique Castelao, Jorge A. Cervilla, Boris Chaumette, Sven Cichon, Aiden Corvin, Nicholas Craddock, David Craig, Franziska Degenhardt, Srdjan Djurovic, Howard J. Edenberg, Ayman H. Fanous, Jerome C. Foo, Andreas J. Forstner, Mark Frye, Janice M. Fullerton, Justine M. Gatt, Pablo V. Gejman, Ina Giegling, Hans J. Grabe, Melissa J. Green, Eugenio H. Grevet, Maria Grigoroiu-Serbanescu, Blanca Gutierrez, Jose Guzman-Parra, Steven P. Hamilton, Marian L. Hamshere, Annette Hartmann, Joanna Hauser, Stefanie Heilmann-Heimbach, Per Hoffmann, Marcus Ising, Ian Jones, Lisa A. Jones, Lina Jonsson, René S. Kahn, John R. Kelsoe, Kenneth S. Kendler, Stefan Kloiber, Karestan C. Koenen, Manolis Kogevinas, Bettina Konte, Marie-Odile Krebs, Mikael Landén, Jacob Lawrence, Marion Leboyer, Phil H. Lee, Douglas F. Levinson, Calwing Liao, Jolanta Lissowska, Susanne Lucae, Fermin Mayoral, Susan L. McElroy, Patrick McGrath, Peter McGuffin, Andrew McQuillin, Sarah E. Medland, Divya Mehta, Ingrid Melle, Yuri Milaneschi, Philip B. Mitchell, Esther Molina, Gunnar Morken, Preben Bo Mortensen, Bertram Müller-Myhsok, Caroline Nievergelt, Vishwajit Nimgaonkar, Markus M. Nöthen, Michael C. O’Donovan, Roel A. Ophoff, Michael J. Owen, Carlos Pato, Michele T. Pato, Brenda W.J.H. Penninx, Jonathan Pimm, Giorgio Pistis, James B. Potash, Robert A. Power, Martin Preisig, Digby Quested, Josep Antoni Ramos-Quiroga, Andreas Reif, Marta Ribasés, Vanesa Richarte, Marcella Rietschel, Margarita Rivera, Andrea Roberts, Gloria Roberts, Guy A. Rouleau, Diego L. Rovaris, Dan Rujescu, Cristina Sánchez-Mora, Alan R. Sanders, Peter R. Schofield, Thomas G. Schulze, Laura J. Scott, Alessandro Serretti, Jianxin Shi, Stanley I. Shyn, Lea Sirignano, Pamela Sklar, Olav B. Smeland, Jordan W. Smoller, Edmund J.S. Sonuga-Barke, Gianfranco Spalletta, John S. Strauss, Beata Świątkowska, Maciej Trzaskowski, Gustavo Turecki, Laura Vilar-Ribó, John B. Vincent, Henry Völzke, James T.R. Walters, Cynthia Shannon Weickert, Thomas W. Weickert, Myrna M. Weissman, Leanne M. Williams, Naomi R. Wray, Clement C. Zai, Allison E. Ashley-Koch, Jean C. Beckham, Elizabeth R. Hauser, Michael A. Hauser, Nathan A. Kimbrel, Jennifer H. Lindquist, Benjamin McMahon, David W. Oslin, Xuejun Qin, , Esben Agerbo, Anders D. Børglum, Gerome Breen, Annette Erlangsen, Tõnu Esko, Joel Gelernter, David M. Hougaard, Ronald C. Kessler, Henry R. Kranzler, Qingqin S. Li, Nicholas G. Martin, Andrew M. McIntosh, Ole Mors, Merete Nordentoft, Catherine M. Olsen, David Porteous, Robert J. Ursano, Danuta Wasserman, Thomas Werge, David C. Whiteman, Cynthia M. Bulik, Hilary Coon, Ditte Demontis, Anna R. Docherty, Po-Hsiu Kuo, Cathryn M. Lewis, J. John Mann, Miguel E. Rentería, Daniel J. Smith, Eli A. Stahl, Murray B. Stein, Fabian Streit, Virginia Willour, Douglas M. RuderferMajor Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Eating Disorders Working Group of the Psychiatric Genomics Consortium, German Borderline Genomics Consortium, MVP Suicide Exemplar Workgroup, VA Million Veteran Program Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Contents: http://creativecommons.org/licenses/by-nc-nd/4.0/ Rect: 296, 114, 457, 122 LastModified: D:20220217110503-05'00' Annotation: Subtype: Link Contents: http://doi.org/10.1016/j.biopsych.2021.05.029 Rect: 297, 72, 445, 80 LastModified: D:20220217110503-05'00' Page: Sequence: 2 Page: Sequence: 3 Annotations: Annotation: Subtype: Link Contents: https://personal.broadinstitute.org/sripke/share_links/zpXkV8INxUg9bayDpLToG4g58TMtjN_PGC_SCZ_w3.0718d.76 Rect: 378, 198, 516, 208 LastModified: D:20220217110503-05'00' Annotation: Subtype: Link Contents: sripke/share_links/zpXkV8INxUg9bayDpLToG4g58TMtjN_PGC_SCZ_w3.0718d.76 Rect: 150, 184, 494, 194 LastModified: D:20220217110503-05'00' Page: Sequence: 4 Page: Sequence: 5 Page: Sequence: 6 Page: Sequence: 7 Page: Sequence: 8 Page: Sequence: 9 Page: Sequence: 10 Page: Sequence: 11 Annotations: Annotation: Subtype: Link Contents: http://www.geneticcluster.org Rect: 389, 169, 484, 177 LastModified: D:20220217110503-05'00' Annotation: Subtype: Link Contents: http://hpc.mssm.edu Rect: 382, 159, 447, 167 LastModified: D:20220217110503-05'00' Page: Sequence: 12 Annotations: Annotation: Subtype: Link Contents: https://tinyurl.com/ISGC2021 Rect: 205, 655, 300, 663 LastModified: D:20220217110503-05'00' Annotation: Subtype: Link Contents: http://www.haplotype-reference-consortium.org/home Rect: 261, 636, 434, 644 LastModified: D:20220217110503-05'00' Annotation: Subtype: Link Contents: https://genetics.opentargets.org Rect: 243, 627, 343, 635 LastModified: D:20220217110503-05'00' Annotation: Subtype: Link Contents: http://ldsc.broadinstitute.org Rect: 379, 627, 469, 635 LastModified: D:20220217110503-05'00' Annotation: Subtype: Link Contents: https://fuma.ctglab.nl Rect: 152, 617, 220, 625 LastModified: D:20220217110503-05'00' Page: Sequence: 13 Page: Sequence: 14 Page: Sequence: 15 Page: Sequence: 16 Page: Sequence: 17 Page: Sequence: 18 Page: Sequence: 19 Page: Sequence: 20 Page: Sequence: 21 Page: Sequence: 22 Page: Sequence: 23 Page: Sequence: 24 Page: Sequence: 25 Annotations: Annotation: Subtype: Link Contents: http://www.who.int/mental_health/prevention/suicide/suicideprevent/en/ Rect: 355, 615, 521, 624 LastModified: D:20220217110503-05'00' Annotation: Subtype: Link Contents: suicide/suicideprevent/en/ Rect: 160, 604, 253, 613 LastModified: D:20220217110503-05'00' Annotation: Subtype: Link Contents: https://www.cdc.gov/injury/wisqars/index.html Rect: 285, 580, 454, 589 LastModified: D:20220217110503-05'00' Page: Sequence: 26 Page: Sequence: 27 Page: Sequence: 28 Page: Sequence: 29 Page: Sequence: 30 Page: Sequence: 31 Page: Sequence: 32 Page: Sequence: 33 Annotations: Annotation: Subtype: Link Contents: https://scicrunch.org/resources Rect: 429, 583, 450, 591 LastModified: D:20220217110503-05'00' Annotation: Subtype: Link Contents: scicrunch.org/resources Rect: 399, 575, 441, 583 LastModified: D:20220217110503-05'00' Annotation: Subtype: Link Contents: resources Rect: 399, 567, 427, 575 LastModified: D:20220217110503-05'00' Annotation: Subtype: Link Contents: http://www.haplotype-reference-consortium.org/home Rect: 288, 474, 386, 482 LastModified: D:20220217110503-05'00' Annotation: Subtype: Link Contents: consortium.org/home Rect: 270, 466, 334, 474 LastModified: D:20220217110503-05'00' Annotation: Subtype: Link Contents: https://genetics.opentargets.org Rect: 270, 158, 364, 166 LastModified: D:20220217110503-05'00' Annotation: Subtype: Link Contents: http://ldsc.broadinstitute.org Rect: 270, 150, 355, 158 LastModified: D:20220217110503-05'00' Annotation: Subtype: Link Contents: https://fuma.ctglab.nl Rect: 359, 150, 380, 158 LastModified: D:20220217110503-05'00' Annotation: Subtype: Link Contents: fuma.ctglab.nl Rect: 270, 142, 313, 150 LastModified: D:20220217110503-05'00' Checksum: 7a0be295 Type: CRC32 Checksum: a2a4f283cf80593c70fe721ac03d36fd Type: MD5 Checksum: 0044d77e5a400eb9ff8e72a3b587b00757eac85e Type: SHA-1