d82da27a41dcb8459bf0e4f6ac53d48f pmc_35047958.pdf 1eb963c6ac2cf605135ab30fa4290ad255707671 pmc_35047958.pdf 1e5d9b41c7f2b01e58dfb936a755928da0e29dc919dfce3cb414fedf98731cd3 pmc_35047958.pdf Title: Systematic Characterization of High-Power Short-Duration Ablation: Insight From an Advanced Virtual Model Subject: Background: High-power short-duration (HPSD) recently emerged as a new approach to radiofrequency (RF) catheter ablation. Keywords: radiofrequency ablation, high-power short-duration, computational modeling, lesion science, ablation catheter Author: Jose M. Guerra Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Mon Nov 8 10:08:55 2021 CET ModDate: Mon Nov 8 10:16:53 2021 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 12 Encrypted: no Page size: 595.26 x 779.52 pts Page rot: 0 File size: 8416205 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- VNNTRL+HelveticaNeueLTStd-Bd Type 1C Custom yes yes no 41 0 QCJJKP+HelveticaNeueLTStd-Lt Type 1C Custom yes yes no 46 0 PIAOFJ+HelveticaNeueLTStd-BdIt Type 1C WinAnsi yes yes no 59 0 AVWRGU+HelveticaNeueLTStd-LtIt Type 1C Custom yes yes no 61 0 OKCHSZ+HelveticaNeueLTStd-MdIt Type 1C WinAnsi yes yes no 66 0 ICYNYC+MTSY Type 1C Custom yes yes yes 68 0 OBAZBH+RMTMI Type 1C WinAnsi yes yes no 70 0 CRKAMY+MinionPro-Bold Type 1C Custom yes yes no 98 0 SIJVMN+MinionPro-Regular Type 1C Custom yes yes no 78 0 PPMLFL+MinionPro-It Type 1C Custom yes yes no 87 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2022-03-10 02:51:41 CET RepresentationInformation: pmc_35047958.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2022-01-24 03:34:43 CET Size: 8416205 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 303 FreeObjects: 17 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: Systematic Characterization of High-Power Short-Duration Ablation: Insight From an Advanced Virtual Model Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@ed9d034 Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6121c9d6 Item: Title: Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@87f383f Children: Item: Title: Virtual Model Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Item: Title: Electrode Tip Design Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Item: Title: Lesion Assessment Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: Complications Assessment Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: Ablation Settings Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Item: Title: Design of the Study Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Children: Item: Title: Safety of HPSD Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: Efficacy of HPSD Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: Repeated HPSD Applications Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Children: Item: Title: Model Validation Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: Safety Margin of HPSD Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: Influence of Catheter Tip Design Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: Catheter Tip Design and Effective Cooling Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: HPSD Lesion Size and Shape Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: HPSD Protocols Comparison Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: Effect of a Second Application Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: Limitations Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Item: Title: Data Availability Statement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: Author Contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: Funding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Item: Title: Acknowledgments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7 Item: Title: Supplementary Material Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cbd213e Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247 Info: Title: Systematic Characterization of High-Power Short-Duration Ablation: Insight From an Advanced Virtual Model Author: Jose M. Guerra Subject: Background: High-power short-duration (HPSD) recently emerged as a new approach to radiofrequency (RF) catheter ablation. Keywords: radiofrequency ablation, high-power short-duration, computational modeling, lesion science, ablation catheter Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Mon Nov 08 10:38:55 CET 2021 ModDate: Mon Nov 08 10:46:53 CET 2021 ID: 0xc4c8a0eb3219c8413df0146552202067, 0xaf91e618ae41d546aed521950950875c Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 279 ImageHeight: 279 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 5100 ImageHeight: 1846 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 3400 ImageHeight: 4100 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 3000 ImageHeight: 2385 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 3400 ImageHeight: 3303 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 3400 ImageHeight: 3712 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 5100 ImageHeight: 5269 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Fonts: Type1: Font: BaseFont: OKCHSZ+HelveticaNeueLTStd-MdIt FontSubset: true FirstChar: 42 LastChar: 135 FontDescriptor: FontName: OKCHSZ+HelveticaNeueLTStd-MdIt Flags: Nonsymbolic FontBBox: -64, -205, 995, 731 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: CRKAMY+MinionPro-Bold FontSubset: true FirstChar: 3 LastChar: 121 FontDescriptor: FontName: CRKAMY+MinionPro-Bold Flags: Symbolic FontBBox: -7, -245, 860, 708 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: ICYNYC+MTSY FontSubset: true FirstChar: 13 LastChar: 21 FontDescriptor: FontName: ICYNYC+MTSY Flags: Symbolic FontBBox: 0, -209, 944, 679 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: OBAZBH+RMTMI FontSubset: true FirstChar: 60 LastChar: 62 FontDescriptor: FontName: OBAZBH+RMTMI Flags: Nonsymbolic, AllCap FontBBox: 0, 0, 683, 455 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: PPMLFL+MinionPro-It FontSubset: true FirstChar: 39 LastChar: 169 FontDescriptor: FontName: PPMLFL+MinionPro-It Flags: Symbolic FontBBox: -142, -257, 1003, 712 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: VNNTRL+HelveticaNeueLTStd-Bd FontSubset: true FirstChar: 0 LastChar: 124 FontDescriptor: FontName: VNNTRL+HelveticaNeueLTStd-Bd Flags: Serif, Symbolic FontBBox: -19, -214, 848, 786 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: PIAOFJ+HelveticaNeueLTStd-BdIt FontSubset: true FirstChar: 42 LastChar: 121 FontDescriptor: FontName: PIAOFJ+HelveticaNeueLTStd-BdIt Flags: Nonsymbolic FontBBox: -63, -182, 717, 731 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AVWRGU+HelveticaNeueLTStd-LtIt FontSubset: true FirstChar: 0 LastChar: 243 FontDescriptor: FontName: AVWRGU+HelveticaNeueLTStd-LtIt Flags: Symbolic FontBBox: -137, -206, 978, 729 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: QCJJKP+HelveticaNeueLTStd-Lt FontSubset: true FirstChar: 0 LastChar: 150 FontDescriptor: FontName: QCJJKP+HelveticaNeueLTStd-Lt Flags: Serif, Symbolic FontBBox: -13, -214, 904, 786 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: SIJVMN+MinionPro-Regular FontSubset: true FirstChar: 2 LastChar: 252 FontDescriptor: FontName: SIJVMN+MinionPro-Regular Flags: Symbolic FontBBox: -26, -257, 956, 713 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true XMP: 2021-11-08T14:38:55+05:30 LaTeX with hyperref package + hypdvips 2021-11-08T14:46:53+05:30 2021-11-08T14:46:53+05:30 application/pdf Background: High-power short-duration (HPSD) recently emerged as a new approach to radiofrequency (RF) catheter ablation. Jose M. 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