8d3e696aba77f70a04a7ce3ef9bab655  pmc_33504892.pdf
9bc8d4aa055bb6c615065585d711fe73fc2dfaa3  pmc_33504892.pdf
1e60abf3079c1b93bb7e0c16e9886d19d28ace62b0deccf223436d25c1492da6  pmc_33504892.pdf

Title:           Integrating gold nanoclusters, folic acid and reduced graphene oxide for nanosensing of glutathione based on “turn-off” fluorescence
Subject:         Scientific Reports, https://doi.org/10.1038/s41598-021-81677-8
Author:          Xin Yi Wong 
Creator:         Springer
Producer:        Adobe PDF Library 15.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version)
CreationDate:    Wed Jan 20 09:38:32 2021 CET
ModDate:         Thu Jan 21 16:23:10 2021 CET
Custom Metadata: yes
Metadata Stream: yes
Tagged:          no
UserProperties:  no
Suspects:        no
Form:            none
JavaScript:      no
Pages:           12
Encrypted:       no
Page size:       595.276 x 782.362 pts
Page rot:        0
File size:       3583579 bytes
Optimized:       no
PDF version:     1.6


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
MAJDQG+Wingdings-Regular             Type 1C           WinAnsi          yes yes yes    421  0
MinionPro-Regular                    Type 1C           Custom           yes no  yes     87  0
DRBTZX+Corbel-Bold                   CID TrueType      Identity-H       yes yes yes     90  0
Corbel2                              TrueType          WinAnsi          yes no  yes     91  0
PGCSLZ+Corbel                        CID TrueType      Identity-H       yes yes yes     92  0
Corbel2                              TrueType          WinAnsi          yes no  yes    364  0
MinionPro-It                         Type 1C           WinAnsi          yes no  yes     88  0
MOEIQF+TimesNewRomanPSMT             CID TrueType      Identity-H       yes yes yes     89  0
ECDMIV+MinionPro-It4                 Type 1C           Custom           yes yes no     121  0
ECDMIV+MTMI                          Type 1C           Custom           yes yes no     122  0
ECDMIV+MinionPro-Regular3            Type 1C           Custom           yes yes no     123  0
ECDMIV+MTSYN2                        Type 1C           Custom           yes yes no     124  0
ECDMIV+MinionPro-It3                 Type 1C           Custom           yes yes no     125  0
ECDMIV+MinionPro-Regular2            Type 1C           Custom           yes yes no     126  0
ECDMIV+MinionPro-It6                 Type 1C           Custom           yes yes no     127  0
ECDMIV+MTSYN4                        Type 1C           Custom           yes yes no     128  0
CZZAGZ+CMEX10                        Type 1C           Custom           yes yes no     129  0
ECDMIV+MTSYN5                        Type 1C           Custom           yes yes no     130  0
ECDMIV+MTMI2                         Type 1C           Custom           yes yes no     131  0
ECDMIV+MTSYN3                        Type 1C           Custom           yes yes no     132  0
ECDMIV+MTSYN                         Type 1C           Custom           yes yes no     133  0
ECDMIV+MinionPro-It5                 Type 1C           Custom           yes yes no     134  0
ECDMIV+MinionPro-It2                 Type 1C           Custom           yes yes no     135  0
MinionPro-Bold                       Type 1C           Custom           yes no  yes    210  0
TimesNewRomanPSMT2                   TrueType          WinAnsi          yes no  yes    326  0


Jhove (Rel. 1.28.0, 2023-05-18)
 Date: 2024-10-02 03:33:39 CEST
 RepresentationInformation: pmc_33504892.pdf
  ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16)
  LastModified: 2023-03-31 12:08:41 CEST
  Size: 3583579
  Format: PDF
  Version: 1.6
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  PDFMetadata: 
   Objects: 488
   FreeObjects: 1
   IncrementalUpdates: 0
   DocumentCatalog: 
    ViewerPreferences: 
     HideToolbar: false
     HideMenubar: false
     HideWindowUI: false
     FitWindow: false
     CenterWindow: false
     DisplayDocTitle: false
     NonFullScreenPageMode: UseNone
     Direction: L2R
     ViewArea: CropBox
     ViewClip: CropBox
     PrintArea: CropBox
     PageClip: CropBox
    PageLayout: SinglePage
    PageMode: UseOutlines
    Language: en-US
    Outlines: 
     Item: 
      Title: Integrating gold nanoclusters, folic acid and reduced graphene oxide for nanosensing of glutathione based on “turn-off” fluorescence
      Children: 
       Item: 
        Title: Experimental
        Children: 
         Item: 
          Title: Reagents and materials. 
         Item: 
          Title: Analytical measurements. 
         Item: 
          Title: Synthesis of BSAAuNCs. 
         Item: 
          Title: Covalent conjugation of FA-rGO. 
         Item: 
          Title: Fluorescence quenching of BSAAuNCs by FA-rGO. 
         Item: 
          Title: Sensing of GSH. 
         Item: 
          Title: Calculation of the signal-to-noise ratio and limit of detection. 
       Item: 
        Title: Results and discussion
        Children: 
         Item: 
          Title: Synthesis and characterization of BSAAuNCs. 
         Item: 
          Title: Characterization of FA-rGO. 
         Item: 
          Title: Loading of BSAAuNCs onto FA-rGO. 
         Item: 
          Title: Effect of addition of GSH on the fluorescence intensity of FA-rGO-BSAAuNCs. 
         Item: 
          Title: Selectivity of the sensing system. 
       Item: 
        Title: Conclusions
       Item: 
        Title: References
       Item: 
        Title: Acknowledgements
   Info: 
    Title: Integrating gold nanoclusters, folic acid and reduced graphene oxide for nanosensing of glutathione based on “turn-off” fluorescence
    Author: Xin Yi Wong 
    Subject: Scientific Reports, https://doi.org/10.1038/s41598-021-81677-8
    Creator: Springer
    Producer: Adobe PDF Library 15.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version)
    CreationDate: Wed Jan 20 10:08:32 CET 2021
    ModDate: Thu Jan 21 16:23:10 CET 2021
   ID: 0xf6cdfcf087d8ba692fe5612c5c73eb86, 0xc4c33fc6d1d67e6e20caacdee0f7e42c
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 2008
      ImageHeight: 733
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 2008
      ImageHeight: 1319
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 2008
      ImageHeight: 1984
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 2008
      ImageHeight: 697
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 2008
      ImageHeight: 1383
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1100
      ImageHeight: 90
      ColorSpace: black is zero
      BitsPerSample: 1
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Name: X
   Fonts: 
    Type0: 
     Font: 
      BaseFont: MOEIQF+TimesNewRomanPSMT
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: DRBTZX+Corbel-Bold
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: PGCSLZ+Corbel
      Encoding: Identity-H
      ToUnicode: true
    Type1: 
     Font: 
      BaseFont: ECDMIV+MTSYN4
      FontSubset: true
      FirstChar: 30
      LastChar: 32
      FontDescriptor: 
       FontName: ECDMIV+MTSYN4
       Flags: Symbolic
       FontBBox: 0, -83, 724, 583
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: CZZAGZ+CMEX10
      FontSubset: true
      FirstChar: 31
      LastChar: 32
      FontDescriptor: 
       FontName: CZZAGZ+CMEX10
       Flags: Symbolic
       FontBBox: 0, -1159, 521, 40
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: ECDMIV+MTSYN5
      FontSubset: true
      FirstChar: 29
      LastChar: 32
      FontDescriptor: 
       FontName: ECDMIV+MTSYN5
       Flags: Symbolic
       FontBBox: 0, -83, 724, 583
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: ECDMIV+MTMI2
      FontSubset: true
      FirstChar: 31
      LastChar: 32
      FontDescriptor: 
       FontName: ECDMIV+MTMI2
       Flags: Symbolic, AllCap
       FontBBox: 0, -207, 369, 676
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: ECDMIV+MTSYN3
      FontSubset: true
      FirstChar: 31
      LastChar: 32
      FontDescriptor: 
       FontName: ECDMIV+MTSYN3
       Flags: Symbolic
       FontBBox: 0, -83, 724, 583
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: MAJDQG+Wingdings-Regular
      FontSubset: true
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: MAJDQG+Wingdings-Regular
       Flags: Nonsymbolic
       FontBBox: 0, -103, 1359, 439
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: ECDMIV+MTSYN
      FontSubset: true
      FirstChar: 29
      LastChar: 32
      FontDescriptor: 
       FontName: ECDMIV+MTSYN
       Flags: Symbolic
       FontBBox: 0, -83, 724, 583
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: ECDMIV+MinionPro-It5
      FontSubset: true
      FirstChar: 28
      LastChar: 32
      FontDescriptor: 
       FontName: ECDMIV+MinionPro-It5
       Flags: Symbolic
       FontBBox: -61, -257, 760, 712
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: ECDMIV+MinionPro-It2
      FontSubset: true
      FirstChar: 22
      LastChar: 32
      FontDescriptor: 
       FontName: ECDMIV+MinionPro-It2
       Flags: Symbolic
       FontBBox: -61, -257, 760, 712
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: MinionPro-Bold
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: MinionPro-Bold
       Flags: Serif, Nonsymbolic
       FontBBox: -319, -360, 1684, 1024
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MinionPro-Regular
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: MinionPro-Regular
       Flags: Serif, Nonsymbolic
       FontBBox: -290, -360, 1684, 989
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MinionPro-It
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: MinionPro-It
       Flags: Serif, Nonsymbolic, Italic
       FontBBox: -201, -360, 1684, 1002
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: ECDMIV+MinionPro-It4
      FontSubset: true
      FirstChar: 28
      LastChar: 32
      FontDescriptor: 
       FontName: ECDMIV+MinionPro-It4
       Flags: Symbolic
       FontBBox: -61, -257, 760, 712
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: ECDMIV+MTMI
      FontSubset: true
      FirstChar: 30
      LastChar: 32
      FontDescriptor: 
       FontName: ECDMIV+MTMI
       Flags: Symbolic, AllCap
       FontBBox: 0, -207, 369, 676
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: ECDMIV+MinionPro-Regular3
      FontSubset: true
      FirstChar: 29
      LastChar: 32
      FontDescriptor: 
       FontName: ECDMIV+MinionPro-Regular3
       Flags: Symbolic, AllCap
       FontBBox: 0, -163, 500, 703
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: ECDMIV+MTSYN2
      FontSubset: true
      FirstChar: 28
      LastChar: 32
      FontDescriptor: 
       FontName: ECDMIV+MTSYN2
       Flags: Symbolic
       FontBBox: 0, -83, 724, 583
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: ECDMIV+MinionPro-It3
      FontSubset: true
      FirstChar: 22
      LastChar: 32
      FontDescriptor: 
       FontName: ECDMIV+MinionPro-It3
       Flags: Symbolic
       FontBBox: -61, -257, 760, 712
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: ECDMIV+MinionPro-Regular2
      FontSubset: true
      FirstChar: 31
      LastChar: 32
      FontDescriptor: 
       FontName: ECDMIV+MinionPro-Regular2
       Flags: Symbolic, AllCap
       FontBBox: 0, -163, 500, 703
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: ECDMIV+MinionPro-It6
      FontSubset: true
      FirstChar: 24
      LastChar: 32
      FontDescriptor: 
       FontName: ECDMIV+MinionPro-It6
       Flags: Symbolic
       FontBBox: -61, -257, 760, 712
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
    TrueType: 
     Font: 
      BaseFont: TimesNewRomanPSMT2
      FirstChar: 32
      LastChar: 121
      FontDescriptor: 
       FontName: TimesNewRomanPSMT2
       Flags: Serif, Nonsymbolic
       FontBBox: -568, -307, 2046, 1040
       FontFile2: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: Corbel2
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: Corbel2
       Flags: Nonsymbolic
       FontBBox: -553, -239, 1110, 952
       FontFile2: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
    CIDFontType2: 
     Font: 
      BaseFont: MOEIQF+TimesNewRomanPSMT
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: MOEIQF+TimesNewRomanPSMT
       Flags: Serif, Symbolic
       FontBBox: -568, -307, 2046, 1040
       FontFile2: true
     Font: 
      BaseFont: PGCSLZ+Corbel
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: PGCSLZ+Corbel
       Flags: Symbolic
       FontBBox: -553, -239, 1110, 952
       FontFile2: true
     Font: 
      BaseFont: DRBTZX+Corbel-Bold
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: DRBTZX+Corbel-Bold
       Flags: Symbolic
       FontBBox: -556, -239, 1155, 952
       FontFile2: true
   XMP: <x:xmpmeta x:xmptk="Adobe XMP Core 5.6-c015 81.159809, 2016/11/11-01:42:16        " xmlns:x="adobe:ns:meta/">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about="" xmlns:crossmark="http://crossref.org/crossmark/1.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:jav="http://www.niso.org/schemas/jav/1.0/" xmlns:pdf="http://ns.adobe.com/pdf/1.3/" xmlns:pdfaExtension="http://www.aiim.org/pdfa/ns/extension/" xmlns:pdfaProperty="http://www.aiim.org/pdfa/ns/property#" xmlns:pdfaSchema="http://www.aiim.org/pdfa/ns/schema#" xmlns:pdfaid="http://www.aiim.org/pdfa/ns/id/" xmlns:pdfx="http://ns.adobe.com/pdfx/1.3/" xmlns:prism="http://prismstandard.org/namespaces/basic/2.0/" xmlns:stEvt="http://ns.adobe.com/xap/1.0/sType/ResourceEvent#" xmlns:xmp="http://ns.adobe.com/xap/1.0/" xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/">
         <xmp:CreateDate>2021-01-20T14:08:32+05:30</xmp:CreateDate>
         <xmp:CreatorTool>Springer</xmp:CreatorTool>
         <xmp:ModifyDate>2021-01-21T16:23:10+01:00</xmp:ModifyDate>
         <xmp:MetadataDate>2021-01-21T16:23:10+01:00</xmp:MetadataDate>
         <dc:format>application/pdf</dc:format>
         <dc:identifier>https://doi.org/10.1038/s41598-021-81677-8</dc:identifier>
         <dc:publisher>
            <rdf:Bag>
               <rdf:li>Nature Publishing Group UK</rdf:li>
            </rdf:Bag>
         </dc:publisher>
         <dc:description>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Scientific Reports, https://doi.org/10.1038/s41598-021-81677-8</rdf:li>
            </rdf:Alt>
         </dc:description>
         <dc:title>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Integrating gold nanoclusters, folic acid and reduced graphene oxide for nanosensing of glutathione based on “turn-off” fluorescence</rdf:li>
            </rdf:Alt>
         </dc:title>
         <dc:creator>
            <rdf:Seq>
               <rdf:li>Xin Yi Wong </rdf:li>
               <rdf:li>Daniel Quesada-González </rdf:li>
               <rdf:li>Sivakumar Manickam </rdf:li>
               <rdf:li>Siu Yee New </rdf:li>
               <rdf:li>Kasturi Muthoosamy </rdf:li>
               <rdf:li>Arben Merkoçi </rdf:li>
            </rdf:Seq>
         </dc:creator>
         <crossmark:DOI>10.1038/s41598-021-81677-8</crossmark:DOI>
         <crossmark:MajorVersionDate>2010-04-23</crossmark:MajorVersionDate>
         <crossmark:CrossmarkDomainExclusive>true</crossmark:CrossmarkDomainExclusive>
         <crossmark:CrossMarkDomains>
            <rdf:Seq>
               <rdf:li>springer.com</rdf:li>
               <rdf:li>springerlink.com</rdf:li>
            </rdf:Seq>
         </crossmark:CrossMarkDomains>
         <prism:url>https://doi.org/10.1038/s41598-021-81677-8</prism:url>
         <prism:doi>10.1038/s41598-021-81677-8</prism:doi>
         <prism:issn>2045-2322</prism:issn>
         <prism:aggregationType>journal</prism:aggregationType>
         <prism:publicationName>Scientific Reports</prism:publicationName>
         <prism:copyright>The Author(s)</prism:copyright>
         <pdfx:CrossmarkMajorVersionDate>2010-04-23</pdfx:CrossmarkMajorVersionDate>
         <pdfx:CrossmarkDomainExclusive>true</pdfx:CrossmarkDomainExclusive>
         <pdfx:doi>10.1038/s41598-021-81677-8</pdfx:doi>
         <pdfx:robots>noindex</pdfx:robots>
         <pdfx:CrossMarkDomains>
            <rdf:Seq>
               <rdf:li>springer.com</rdf:li>
               <rdf:li>springerlink.com</rdf:li>
            </rdf:Seq>
         </pdfx:CrossMarkDomains>
         <jav:journal_article_version>VoR</jav:journal_article_version>
         <xmpMM:DocumentID>uuid:be22620a-3c67-46d3-871e-7a8cd9faea4f</xmpMM:DocumentID>
         <xmpMM:InstanceID>uuid:258f7675-8d1a-4c83-b5e2-963a74fc1db6</xmpMM:InstanceID>
         <xmpMM:RenditionClass>default</xmpMM:RenditionClass>
         <xmpMM:VersionID>1</xmpMM:VersionID>
         <xmpMM:History>
            <rdf:Seq>
               <rdf:li rdf:parseType="Resource">
                  <stEvt:action>converted</stEvt:action>
                  <stEvt:instanceID>uuid:9634cc4a-d29b-4892-b064-35df3b9d0929</stEvt:instanceID>
                  <stEvt:parameters>converted to PDF/A-2b</stEvt:parameters>
                  <stEvt:softwareAgent>pdfToolbox</stEvt:softwareAgent>
                  <stEvt:when>2021-01-20T14:09:31+05:30</stEvt:when>
               </rdf:li>
            </rdf:Seq>
         </xmpMM:History>
         <pdf:Producer>Adobe PDF Library 15.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version)</pdf:Producer>
         <pdfaid:part>2</pdfaid:part>
         <pdfaid:conformance>B</pdfaid:conformance>
         <pdfaExtension:schemas>
            <rdf:Bag>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/pdfx/1.3/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdfx</pdfaSchema:prefix>
                  <pdfaSchema:schema>Adobe Document Info PDF eXtension Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Mirrors crossmark:MajorVersionDate</pdfaProperty:description>
                           <pdfaProperty:name>CrossmarkMajorVersionDate</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Mirrors crossmark:CrossmarkDomainExclusive</pdfaProperty:description>
                           <pdfaProperty:name>CrossmarkDomainExclusive</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Mirrors crossmark:DOI</pdfaProperty:description>
                           <pdfaProperty:name>doi</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Mirrors crossmark:CrosMarkDomains</pdfaProperty:description>
                           <pdfaProperty:name>CrossMarkDomains</pdfaProperty:name>
                           <pdfaProperty:valueType>seq Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>A name object indicating whether the document has been modified to include trapping information</pdfaProperty:description>
                           <pdfaProperty:name>robots</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>ID of PDF/X standard</pdfaProperty:description>
                           <pdfaProperty:name>GTS_PDFXVersion</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Conformance level of PDF/X standard</pdfaProperty:description>
                           <pdfaProperty:name>GTS_PDFXConformance</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Company creating the PDF</pdfaProperty:description>
                           <pdfaProperty:name>Company</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Date when document was last modified</pdfaProperty:description>
                           <pdfaProperty:name>SourceModified</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://crossref.org/crossmark/1.0/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>crossmark</pdfaSchema:prefix>
                  <pdfaSchema:schema>Crossmark Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Usual same as prism:doi</pdfaProperty:description>
                           <pdfaProperty:name>DOI</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>The date when a publication was publishe.</pdfaProperty:description>
                           <pdfaProperty:name>MajorVersionDate</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>CrossmarkDomainExclusive</pdfaProperty:description>
                           <pdfaProperty:name>CrossmarkDomainExclusive</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>CrossMarkDomains</pdfaProperty:description>
                           <pdfaProperty:name>CrossMarkDomains</pdfaProperty:name>
                           <pdfaProperty:valueType>seq Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://prismstandard.org/namespaces/basic/2.0/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>prism</pdfaSchema:prefix>
                  <pdfaSchema:schema>Prism Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>This element provides the url for an article or unit of content. The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary.</pdfaProperty:description>
                           <pdfaProperty:name>url</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>The Digital Object Identifier for the article.
The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL). </pdfaProperty:description>
                           <pdfaProperty:name>doi</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>ISSN for an electronic version of the issue in which the resource occurs. Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version.</pdfaProperty:description>
                           <pdfaProperty:name>issn</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Volume number</pdfaProperty:description>
                           <pdfaProperty:name>volume</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Issue number</pdfaProperty:description>
                           <pdfaProperty:name>number</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Starting page</pdfaProperty:description>
                           <pdfaProperty:name>startingPage</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Ending page</pdfaProperty:description>
                           <pdfaProperty:name>endingPage</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>The aggregation type specifies the unit of aggregation for a content collection. Comment PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary. </pdfaProperty:description>
                           <pdfaProperty:name>aggregationType</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Title of the magazine, or other publication, in which a resource was/will be published. Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.”</pdfaProperty:description>
                           <pdfaProperty:name>publicationName</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Copyright</pdfaProperty:description>
                           <pdfaProperty:name>copyright</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/pdf/1.3/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdf</pdfaSchema:prefix>
                  <pdfaSchema:schema>Adobe PDF Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>A name object indicating whether the document has been modified to include trapping information</pdfaProperty:description>
                           <pdfaProperty:name>Trapped</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/xap/1.0/mm/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>xmpMM</pdfaSchema:prefix>
                  <pdfaSchema:schema>XMP Media Management Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>UUID based identifier for specific incarnation of a document</pdfaProperty:description>
                           <pdfaProperty:name>InstanceID</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>The common identifier for all versions and renditions of a document.</pdfaProperty:description>
                           <pdfaProperty:name>DocumentID</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>The common identifier for all versions and renditions of a document.</pdfaProperty:description>
                           <pdfaProperty:name>OriginalDocumentID</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://www.aiim.org/pdfa/ns/id/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdfaid</pdfaSchema:prefix>
                  <pdfaSchema:schema>PDF/A ID Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Part of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>part</pdfaProperty:name>
                           <pdfaProperty:valueType>Integer</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Amendment of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>amd</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Conformance level of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>conformance</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://www.niso.org/schemas/jav/1.0/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>jav</pdfaSchema:prefix>
                  <pdfaSchema:schema>NISO</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Values for Journal Article Version are one of the following:
AO = Author’s Original
SMUR = Submitted Manuscript Under Review
AM = Accepted Manuscript
P = Proof
VoR = Version of Record
CVoR = Corrected Version of Record
EVoR = Enhanced Version of Record</pdfaProperty:description>
                           <pdfaProperty:name>journal_article_version</pdfaProperty:name>
                           <pdfaProperty:valueType>Closed Choice of Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
            </rdf:Bag>
         </pdfaExtension:schemas>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Sequence: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 181, 279, 183, 267
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 186, 279, 189, 267
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 338, 269, 341, 257
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 342, 269, 345, 257
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 347, 269, 350, 257
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 353, 269, 355, 257
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 254, 259, 257, 247
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 321, 259, 324, 247
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 344, 259, 347, 247
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 546, 259, 552, 247
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 482, 249, 488, 237
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 489, 249, 495, 237
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 506, 219, 512, 207
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 194, 199, 199, 187
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 202, 199, 208, 187
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 481, 675, 556, 658
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
    Page: 
     Sequence: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 345, 734, 351, 722
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 408, 734, 414, 722
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 460, 734, 465, 722
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 230, 724, 235, 712
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 266, 704, 272, 692
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 275, 704, 281, 692
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 273, 694, 278, 682
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 280, 694, 286, 682
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 287, 674, 292, 662
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 295, 674, 301, 662
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 172, 654, 178, 642
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 462, 644, 467, 632
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 357, 624, 363, 612
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 201, 614, 206, 602
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 501, 614, 507, 602
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 510, 614, 516, 602
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 272, 594, 278, 582
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 546, 574, 552, 562
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 319, 554, 325, 542
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 231, 524, 237, 512
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 238, 524, 244, 512
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 245, 524, 251, 512
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 306, 514, 312, 502
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 313, 514, 319, 502
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 449, 494, 454, 482
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 458, 494, 463, 482
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 267, 474, 273, 462
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 171, 454, 176, 442
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 178, 454, 183, 442
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 417, 444, 423, 432
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 424, 444, 430, 432
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 433, 444, 439, 432
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 318, 424, 323, 412
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 172, 404, 178, 392
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 546, 384, 552, 372
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 391, 344, 396, 332
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 400, 344, 405, 332
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 217, 324, 222, 312
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 208, 314, 214, 302
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 222, 294, 227, 282
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 229, 294, 234, 282
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 302, 254, 307, 242
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 309, 254, 314, 242
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 469, 82, 474, 70
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
     Thumb: true
    Page: 
     Sequence: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 546, 632, 552, 620
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 173, 530, 179, 518
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 315, 284, 319, 272
       Flags: Print
       AppearanceDictionary: true
       Destination: 103
      Annotation: 
       Subtype: Link
       Rect: 466, 251, 470, 239
       Flags: Print
       AppearanceDictionary: true
       Destination: 103
      Annotation: 
       Subtype: Link
       Rect: 494, 251, 499, 239
       Flags: Print
       AppearanceDictionary: true
       Destination: 103
      Annotation: 
       Subtype: Link
       Rect: 462, 115, 468, 103
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 281, 105, 286, 93
       Flags: Print
       AppearanceDictionary: true
       Destination: 303
     Thumb: true
    Page: 
     Sequence: 4
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 241, 404, 246, 392
       Flags: Print
       AppearanceDictionary: true
       Destination: 186
      Annotation: 
       Subtype: Link
       Rect: 502, 384, 506, 372
       Flags: Print
       AppearanceDictionary: true
       Destination: 186
      Annotation: 
       Subtype: Link
       Rect: 457, 374, 463, 362
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 182, 344, 187, 332
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 546, 344, 552, 332
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 381, 334, 386, 322
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 367, 304, 373, 292
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 374, 304, 380, 292
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 452, 274, 457, 262
       Flags: Print
       AppearanceDictionary: true
       Destination: 215
      Annotation: 
       Subtype: Link
       Rect: 373, 244, 377, 232
       Flags: Print
       AppearanceDictionary: true
       Destination: 215
      Annotation: 
       Subtype: Link
       Rect: 369, 204, 374, 192
       Flags: Print
       AppearanceDictionary: true
       Destination: 215
      Annotation: 
       Subtype: Link
       Rect: 270, 134, 276, 122
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 384, 113, 388, 100
       Flags: Print
       AppearanceDictionary: true
       Destination: 238
      Annotation: 
       Subtype: Link
       Rect: 546, 102, 552, 90
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 458, 82, 463, 70
       Flags: Print
       AppearanceDictionary: true
       Destination: 238
     Thumb: true
    Page: 
     Sequence: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 255, 361, 259, 349
       Flags: Print
       AppearanceDictionary: true
       Destination: 238
      Annotation: 
       Subtype: Link
       Rect: 465, 319, 471, 307
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 343, 289, 349, 277
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 504, 279, 509, 267
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 228, 249, 232, 237
       Flags: Print
       AppearanceDictionary: true
       Destination: 263
      Annotation: 
       Subtype: Link
       Rect: 442, 197, 447, 185
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 464, 187, 469, 175
       Flags: Print
       AppearanceDictionary: true
       Destination: 263
      Annotation: 
       Subtype: Link
       Rect: 266, 167, 271, 155
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 270, 147, 276, 135
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 346, 127, 352, 115
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 236, 117, 241, 105
       Flags: Print
       AppearanceDictionary: true
       Destination: 303
      Annotation: 
       Subtype: Link
       Rect: 379, 87, 383, 75
       Flags: Print
       AppearanceDictionary: true
       Destination: 303
     Thumb: true
    Page: 
     Sequence: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 402, 196, 405, 184
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 365, 186, 371, 174
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 288, 176, 291, 164
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 392, 146, 397, 134
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 399, 146, 404, 134
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 336, 136, 339, 124
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 313, 126, 316, 114
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 231, 116, 234, 104
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 380, 86, 385, 74
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 257, 56, 263, 44
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 266, 56, 272, 44
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
     Thumb: true
    Page: 
     Sequence: 7
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 455, 211, 461, 199
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 352, 181, 358, 169
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 390, 181, 396, 169
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 548, 181, 554, 169
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 271, 141, 277, 129
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 218, 131, 224, 119
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 225, 131, 231, 119
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 238, 121, 244, 109
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 275, 111, 280, 99
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 546, 101, 552, 89
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 511, 456, 513, 447
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 511, 444, 515, 435
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 511, 433, 515, 423
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 511, 421, 515, 412
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 511, 409, 515, 400
       Flags: Print
       AppearanceDictionary: true
       Destination: 333
      Annotation: 
       Subtype: Link
       Rect: 511, 398, 515, 388
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 511, 386, 515, 377
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 511, 374, 515, 365
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 511, 363, 515, 353
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 511, 351, 515, 342
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 511, 339, 515, 330
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 511, 328, 515, 318
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
      Annotation: 
       Subtype: Link
       Rect: 511, 316, 515, 306
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 511, 304, 515, 295
       Flags: Print
       AppearanceDictionary: true
       Destination: 318
     Thumb: true
    Page: 
     Sequence: 8
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 538, 241, 543, 229
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 491, 221, 497, 209
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 200, 181, 206, 169
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 207, 181, 213, 169
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 349, 109, 353, 97
       Flags: Print
       AppearanceDictionary: true
       Destination: 303
     Thumb: true
    Page: 
     Sequence: 9
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 238, 734, 244, 722
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 245, 734, 251, 722
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
     Thumb: true
    Page: 
     Sequence: 10
     Thumb: true
    Page: 
     Sequence: 11
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 514, 186, 554, 173
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 155, 175, 275, 163
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 351, 146, 443, 133
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
    Page: 
     Sequence: 12
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 358, 664, 517, 652
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
  Checksum: 7e622ece
   Type: CRC32
  Checksum: 8d3e696aba77f70a04a7ce3ef9bab655
   Type: MD5
  Checksum: 9bc8d4aa055bb6c615065585d711fe73fc2dfaa3
   Type: SHA-1
  Checksum: 1e60abf3079c1b93bb7e0c16e9886d19d28ace62b0deccf223436d25c1492da6
   Type: SHA-256