a313f8398fca9c2fa915d045cc38a7ea pmc_33530620.pdf d74513b850d30732761bbecfb2a57701eee9fb1e pmc_33530620.pdf a10efe993c823c58c75d7b9a0beedf95d95fd4dbc12b4cb111edb746a1050cde pmc_33530620.pdf Title: Anthropogenic Infection of Cats during the 2020 COVID-19 Pandemic Subject: COVID-19 is a severe acute respiratory syndrome (SARS) caused by a new coronavirus (CoV), SARS-CoV-2, which is closely related to SARS-CoV that jumped the animal–human species barrier and caused a disease outbreak in 2003. SARS-CoV-2 is a betacoronavirus that was first described in 2019, unrelated to the commonly occurring feline coronavirus (FCoV) that is an alphacoronavirus associated with feline infectious peritonitis (FIP). SARS-CoV-2 is highly contagious and has spread globally within a few months, resulting in the current pandemic. Felids have been shown to be susceptible to SARS-CoV-2 infection. Particularly in the Western world, many people live in very close contact with their pet cats, and natural infections of cats in COVID-19-positive households have been described in several countries. In this review, the European Advisory Board on Cat Diseases (ABCD), a scientifically independent board of experts in feline medicine from 11 European Countries, discusses the current status of SARS-CoV infections in cats. The review examines the host range of SARS-CoV-2 and human-to-animal transmissions, including infections in domestic and non-domestic felids, as well as mink-to-human/-cat transmission. It summarises current data on SARS-CoV-2 prevalence in domestic cats and the results of experimental infections of cats and provides expert opinions on the clinical relevance and prevention of SARS-CoV-2 infection in cats. Keywords: SARS-CoV-2; COVID-19; domestic cats; wild felids; companion animals; minks; experimental infection; human-to-feline transmission; one health Author: Margaret J. Hosie, Regina Hofmann-Lehmann, Katrin Hartmann, Herman Egberink, Uwe Truyen, Diane D. Addie, Sándor Belák, Corine Boucraut-Baralon, Tadeusz Frymus, Albert Lloret, Hans Lutz, Fulvio Marsilio, Maria Grazia Pennisi, Séverine Tasker, Etienne Thiry and Karin Möstl Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Fri Jan 29 06:39:50 2021 CET ModDate: Fri Jan 29 06:46:00 2021 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 13 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 314884 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- SBPPEB+VnURWPalladioL Type 1 Custom yes yes no 10 0 MSWYSJ+URWPalladioL-Ital Type 1 Custom yes yes no 15 0 DXJMZE+URWPalladioL-Bold Type 1 Custom yes yes no 20 0 IBZTDG+URWPalladioL-Roma Type 1 Custom yes yes no 24 0 GIFXFT+VnURWPalladioL-Bold Type 1 Custom yes yes no 28 0 HOWKDX+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 36 0 MCBCCI+SourceSansRoman-Regular Type 1C Custom yes yes no 58 0 MCBCCM+SourceSansRoman.613wght Type 1C Custom yes yes no 62 0 MCBCCO+SourceSansRoman-Bold Type 1C Custom yes yes no 66 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-05-27 02:49:21 CEST RepresentationInformation: pmc_33530620.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-03-31 12:08:44 CEST Size: 314884 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 396 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@44c8afef Item: Title: Other Human Coronaviruses Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7b69c6ba Item: Title: SARS-CoV Infections in Cats Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@46daef40 Item: Title: Host Range of SARS-CoV-2 Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@12f41634 Item: Title: Evidence of Human-to-Cat Transmission of SARS-CoV-2 Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@13c27452 Item: Title: Evidence of Mink-to-Cat and Mink-to-Human Transmission Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@262b2c86 Item: Title: Prevalence of SARS-CoV-2 Infection in Domestic Animals Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@371a67ec Item: Title: Evidence of Human-to-Non-Domestic Cat Transmission of SARS-CoV-2 Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5ed828d Item: Title: Experimental Infection of Cats with SARS-CoV-2 Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@50d0686 Item: Title: Stability of Coronaviruses Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a3d45bd Item: Title: Diagnosis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1e7c7811 Item: Title: Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@77ec78b9 Item: Title: Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1a3869f4 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@a38d7a3 Info: Title: Anthropogenic Infection of Cats during the 2020 COVID-19 Pandemic Author: Margaret J. Hosie, Regina Hofmann-Lehmann, Katrin Hartmann, Herman Egberink, Uwe Truyen, Diane D. Addie, Sándor Belák, Corine Boucraut-Baralon, Tadeusz Frymus, Albert Lloret, Hans Lutz, Fulvio Marsilio, Maria Grazia Pennisi, Séverine Tasker, Etienne Thiry and Karin Möstl Subject: COVID-19 is a severe acute respiratory syndrome (SARS) caused by a new coronavirus (CoV), SARS-CoV-2, which is closely related to SARS-CoV that jumped the animal human species barrier and caused a disease outbreak in 2003. SARS-CoV-2 is a betacoronavirus that was first described in 2019, unrelated to the commonly occurring feline coronavirus (FCoV) that is an alphacoronavirus associated with feline infectious peritonitis (FIP). SARS-CoV-2 is highly contagious and has spread globally within a few months, resulting in the current pandemic. Felids have been shown to be susceptible to SARS-CoV-2 infection. Particularly in the Western world, many people live in very close contact with their pet cats, and natural infections of cats in COVID-19-positive households have been described in several countries. In this review, the European Advisory Board on Cat Diseases (ABCD), a scientifically independent board of experts in feline medicine from 11 European Countries, discusses the current status of SARS-CoV infections in cats. The review examines the host range of SARS-CoV-2 and human-to-animal transmissions, including infections in domestic and non-domestic felids, as well as mink-to-human/-cat transmission. It summarises current data on SARS-CoV-2 prevalence in domestic cats and the results of experimental infections of cats and provides expert opinions on the clinical relevance and prevention of SARS-CoV-2 infection in cats. 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