adbce5b1e899ec1a48b1cc16a85baa27 pmc_33546212.pdf 7652ffaa63bc08938c68c192c8a9b2e4e5e05095 pmc_33546212.pdf 030d990c8a7a52f5dafb40044f3e39c016551c0fa08179ac66c3067afffb4b37 pmc_33546212.pdf Title: Prevalence of Fetal Alcohol Spectrum Disorders (FASD) among Children Adopted from Eastern European Countries: Russia and Ukraine Subject: Fetal alcohol spectrum disorder (FASD) is a leading cause of neurodevelopmental disorders. Children adopted internationally from countries where alcohol consumption during pregnancy is very high are at greater risk for FASD. Lack of expertise in diagnosing FASD and mixed neurodevelopmental and behavioral signs due to abandonment complicate a timely diagnosis. The aim of this study was to determine the prevalence of FASD in adopted children. Children between the ages of 8 and 24 adopted from Russia and Ukraine were evaluated for clinical and historical features of FASD. Of the 162 children evaluated, 81 (50%) met FASD diagnostic criteria. Thirty-three (20.4%) children had fetal alcohol syndrome (FAS), 28 (17.2%) had partial FAS, 2 (1.2%) had alcohol-related birth defects (ARBD) and 18 (11.1%) had alcohol-related neurodevelopmental disorder (ARND). Of the 81 children in which fetal alcohol exposure could not be confirmed, many had manifestations that would have established a diagnosis of FASD if a history of maternal alcohol consumption was confirmed. In a population of children with a high risk of prenatal alcohol exposure (adoptees from Eastern European countries), at least 50% showed manifestations associated with FASD. The reported prevalence in this study is in line with the results obtained in a previous study as well as in orphanages of origin. Keywords: fetal alcohol spectrum disorders (FASD); adopted children; cognitive disorder; neurodevelopment impairment; prenatal exposure to alcohol (PEA); alcohol-exposed pregnancies; alcohol Author: Joan Colom, Lidia Segura-García, Adriana Bastons-Compta, Marta Astals, Vicente Andreu-Fernandez, Natalia Barcons, Raquel Vidal, Ana I. Ibar, Vicky Fumadó, Nuria Gómez, Agnés Russiñol and Oscar Garcia-Algar Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Thu Feb 4 03:11:37 2021 CET ModDate: Thu Feb 4 03:15:12 2021 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 12 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 750484 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- XWOCXD+VnURWPalladioL-Bold Type 1 Custom yes yes no 10 0 DSBBYX+VnURWPalladioL Type 1 Custom yes yes no 15 0 WFHDUF+URWPalladioL-Ital Type 1 Custom yes yes no 19 0 FDUYMI+URWPalladioL-Bold Type 1 Custom yes yes no 24 0 EYQEHV+URWPalladioL-Roma Type 1 Custom yes yes no 28 0 LWQXII+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 36 0 IRWHZX+TimesNewRomanPSMT Type 1C WinAnsi yes yes no 39 0 MCBCCI+SourceSansRoman-Regular Type 1C Custom yes yes no 61 0 MCBCCM+SourceSansRoman.613wght Type 1C Custom yes yes no 65 0 MCBCCO+SourceSansRoman-Bold Type 1C Custom yes yes no 69 0 KOSUXD+CMSY10 Type 1 Builtin yes yes no 81 0 RHAWTP+EURM10 Type 1 Builtin yes yes no 94 0 PNNOKN+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 108 0 PNNOKJ+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 111 0 PNNOKL+PalatinoLinotype TrueType WinAnsi yes yes no 114 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-05-27 02:49:11 CEST RepresentationInformation: pmc_33546212.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-03-31 12:08:46 CEST Size: 750484 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 280 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@44c8afef Children: Item: Title: Alcohol Consumption and Impact on Health and Harm to Others Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7b69c6ba Item: Title: Epidemiological Data of Prenatal Exposure to Alcohol (PEA) and FASD Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@46daef40 Item: Title: FASD Prevalence in Adopted Children from Eastern European Countries Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@12f41634 Item: Title: Patients and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@13c27452 Children: Item: Title: Sampling Methods and Description Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@262b2c86 Item: Title: Recruitment Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@371a67ec Item: Title: Assessment Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5ed828d Item: Title: Statistical Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@50d0686 Item: Title: Ethical Aspects Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a3d45bd Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1e7c7811 Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@77ec78b9 Children: Item: Title: Comparison with Other Studies (Strength of the Study) Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1a3869f4 Item: Title: Limitations Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@a38d7a3 Item: Title: Challenges and Opportunities under a Public Health Perspective Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@77f99a05 Item: Title: Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@63440df3 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3aeaafa6 Info: Title: Prevalence of Fetal Alcohol Spectrum Disorders (FASD) among Children Adopted from Eastern European Countries: Russia and Ukraine Author: Joan Colom, Lidia Segura-García, Adriana Bastons-Compta, Marta Astals, Vicente Andreu-Fernandez, Natalia Barcons, Raquel Vidal, Ana I. Ibar, Vicky Fumadó, Nuria Gómez, Agnés Russiñol and Oscar Garcia-Algar Subject: Fetal alcohol spectrum disorder (FASD) is a leading cause of neurodevelopmental disorders. Children adopted internationally from countries where alcohol consumption during pregnancy is very high are at greater risk for FASD. Lack of expertise in diagnosing FASD and mixed neurodevelopmental and behavioral signs due to abandonment complicate a timely diagnosis. The aim of this study was to determine the prevalence of FASD in adopted children. Children between the ages of 8 and 24 adopted from Russia and Ukraine were evaluated for clinical and historical features of FASD. Of the 162 children evaluated, 81 (50%) met FASD diagnostic criteria. Thirty-three (20.4%) children had fetal alcohol syndrome (FAS), 28 (17.2%) had partial FAS, 2 (1.2%) had alcohol-related birth defects (ARBD) and 18 (11.1%) had alcohol-related neurodevelopmental disorder (ARND). Of the 81 children in which fetal alcohol exposure could not be confirmed, many had manifestations that would have established a diagnosis of FASD if a history of maternal alcohol consumption was confirmed. In a population of children with a high risk of prenatal alcohol exposure (adoptees from Eastern European countries), at least 50% showed manifestations associated with FASD. The reported prevalence in this study is in line with the results obtained in a previous study as well as in orphanages of origin. Keywords: fetal alcohol spectrum disorders (FASD); adopted children; cognitive disorder; neurodevelopment impairment; prenatal exposure to alcohol (PEA); alcohol-exposed pregnancies; alcohol Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Thu Feb 04 03:11:37 CET 2021 ModDate: Thu Feb 04 03:15:12 CET 2021 ID: 0x0a550577b2fd13b660a577d9e3e6cd49, 0x0a550577b2fd13b660a577d9e3e6cd49 Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: KOSUXD+CMSY10 FontSubset: true FirstChar: 0 LastChar: 21 FontDescriptor: FontName: KOSUXD+CMSY10 Flags: Symbolic FontBBox: -29, -960, 1116, 775 FontFile: true Font: BaseFont: WFHDUF+URWPalladioL-Ital FontSubset: true FirstChar: 40 LastChar: 121 FontDescriptor: FontName: WFHDUF+URWPalladioL-Ital Flags: Symbolic FontBBox: -170, -305, 1010, 941 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: FDUYMI+URWPalladioL-Bold FontSubset: true FirstChar: 3 LastChar: 241 FontDescriptor: FontName: FDUYMI+URWPalladioL-Bold 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