1cd839062776ad08b407bc3ff2b0c44f  pmc_33546694.pdf
8bcf6ece102cac8b3c9386b21e35b2900a6661f7  pmc_33546694.pdf
c88f7fb64fcebe309ab50794955d1f571637c3aa09ced6b69150d7819a5951cc  pmc_33546694.pdf

Title:          The mutational landscape of human olfactory G protein-coupled receptors
Subject:        BMC Biology, 2021, doi:10.1186/s12915-021-00962-0
Keywords:       Olfactory receptors,OR,Natural variants,Mutations,7-TM receptors,G protein-coupled receptor,GPCR,Sensegenomics,Database
Author:         Ramón Cierco Jimenez
Creator:        Arbortext Advanced Print Publisher 9.1.440/W Unicode
Producer:       Acrobat Distiller 10.0.0 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version)
CreationDate:   Tue Feb  2 09:42:32 2021 CET
ModDate:        Fri Feb  5 17:50:16 2021 CET
Tagged:         no
UserProperties: no
Suspects:       no
Form:           none
JavaScript:     no
Pages:          15
Encrypted:      no
Page size:      595.276 x 790.866 pts
Page rot:       0
File size:      7016977 bytes
Optimized:      no
PDF version:    1.3


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
MyriadPro-Regular                    Type 1C           Custom           yes no  yes     24  0
FPFDHD+AdvTTaf7f9f4f.B               Type 1C           WinAnsi          yes yes no      22  0
FPFEPK+AdvTTe45e47d2                 Type 1C           WinAnsi          yes yes no      23  0
FPFEPL+AdvTTb5929f4c                 Type 1C           WinAnsi          yes yes no      78  0
FPFFCL+AdvTT99c4c969                 Type 1C           WinAnsi          yes yes no      79  0
FPFFOI+AdvTT7329fd89.I               Type 1C           WinAnsi          yes yes no      25  0
FPFGCI+AdvTT86d47313                 Type 1C           WinAnsi          yes yes no      19  0
FPFGCJ+AdvTT86d47313+20              Type 1C           Custom           yes yes yes     20  0
FPFGDK+AdvTT86d47313+03              Type 1C           Custom           yes yes yes     21  0
FPGKIO+AdvTTb5929f4c+20              Type 1C           Custom           yes yes yes    321  0
FPHPIO+AdvTT1b53b5fb.I               Type 1C           WinAnsi          yes yes no     372  0
FPILBI+AdvTT83913201.I               Type 1C           WinAnsi          yes yes no     472  0
FPKJGA+AdvTT86d47313+22              Type 1C           Custom           yes yes yes    152  0
FPKJFP+AdvTT8861b38f.I               Type 1C           WinAnsi          yes yes no     146  0
FPKJIB+AdvTT99c4c969+20              Type 1C           WinAnsi          yes yes no     214  0
FPKJIA+AdvTTb5929f4c+03              Type 1C           Custom           yes yes yes    220  0
FPKJMB+AdvTTaf7f9f4f.B+20            Type 1C           WinAnsi          yes yes no     240  0


Jhove (Rel. 1.22.1, 2019-04-17)
 Date: 2023-10-21 02:39:21 CEST
 RepresentationInformation: pmc_33546694.pdf
  ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17)
  LastModified: 2023-03-31 12:08:46 CEST
  Size: 7016977
  Format: PDF
  Version: 1.3
  Status: Well-Formed, but not valid
  SignatureMatches:
   PDF-hul
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR1' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR2' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR3' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR4' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR5' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR6' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR10' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR11' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR12' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR13' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR14' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR10' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR15' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR16' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR17' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR18' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR20' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR21' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR22' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR23' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR24' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR25' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR26' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR30' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR31' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR32' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR33' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR21' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR34' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR35' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR21' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR36' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR37' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR38' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR42' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR43' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR44' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR45' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR46' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR47' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR48' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR49' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR33' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_Sec14' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR30' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR50' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR51' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR52' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR53' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR54' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR55' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR56' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR57' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR29' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR58' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR26' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR38' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR42' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR21' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR59' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR60' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR14' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR21' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR24' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR25' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR33' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_CR32' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_' cannot be found
   Offset: 5501169
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_' cannot be found
   Offset: 5501169
  MIMEtype: application/pdf
  PDFMetadata: 
   Objects: 596
   FreeObjects: 1
   IncrementalUpdates: 0
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseNone
    Outlines: 
     Item: 
      Title: Abstract
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003
      Children: 
       Item: 
        Title: Background
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191
       Item: 
        Title: Results
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb
       Item: 
        Title: Conclusion
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431
     Item: 
      Title: Background
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6
     Item: 
      Title: Results
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a
      Children: 
       Item: 
        Title: Allele frequencies and population distribution of the variant dataset
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71
       Item: 
        Title: Topological assignment to sequence variants
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2
       Item: 
        Title: Mutability landscapes of amino acids changes
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9
       Item: 
        Title: Use of topological annotation, substitution metrics, and allele frequencies in the impact evaluation of the mutations
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f
        Children: 
         Item: 
          Title: Extracellular loop 2 at the conserved Cys45.50
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78
         Item: 
          Title: Transmembrane helix 2 at the conserved Asp2.50
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee
         Item: 
          Title: Transmembrane helix 7 at the conserved Pro7.50
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f
         Item: 
          Title: Transmembrane helix 3 at the conserved Arg3.50
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1
       Item: 
        Title: Development of an interactive application to explore the human OR mutation data
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d
     Item: 
      Title: Discussion
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89
     Item: 
      Title: Conclusions
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9
     Item: 
      Title: Methods
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e
      Children: 
       Item: 
        Title: Data acquisition and filtering
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b
       Item: 
        Title: Topological mapping and BW annotation
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b
       Item: 
        Title: Impact evaluation of coding sequence variants
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31
       Item: 
        Title: Development of an interactive database with the annotated variation data
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107
     Item: 
      Title: Supplementary Information
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e
     Item: 
      Title: Abbreviations
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7
     Item: 
      Title: Acknowledgements
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cbd213e
     Item: 
      Title: Authors’ contributions
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247
     Item: 
      Title: Funding
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3ecd23d9
     Item: 
      Title: Availability of data and materials
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@569cfc36
     Item: 
      Title: Ethics approval and consent to participate
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@43bd930a
     Item: 
      Title: Consent for publication
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@33723e30
     Item: 
      Title: Competing interests
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@64f6106c
     Item: 
      Title: Author details
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@553a3d88
     Item: 
      Title: References
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a30d1e6
     Item: 
      Title: Publisher’s Note
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5891e32e
   Info: 
    Title: The mutational landscape of human olfactory G protein-coupled receptors
    Author: Ramón Cierco Jimenez
    Subject: BMC Biology, 2021, doi:10.1186/s12915-021-00962-0
    Keywords: Olfactory receptors,OR,Natural variants,Mutations,7-TM receptors,G protein-coupled receptor,GPCR,Sensegenomics,Database
    Creator: Arbortext Advanced Print Publisher 9.1.440/W Unicode
    Producer: Acrobat Distiller 10.0.0 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version)
    CreationDate: Tue Feb 02 09:42:32 CET 2021
    ModDate: Fri Feb 05 17:50:16 CET 2021
   ID: 0xf5a1a40c9bb758265acbb81dcff7cf45, 0x6e73e45be04ddfd00399a888bf2f75a0
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 176
      ImageHeight: 182
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: Perceptual
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 688
      ImageHeight: 126
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 33
      ImageHeight: 63
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1949
      ImageHeight: 1233
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: Perceptual
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1949
      ImageHeight: 2079
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: Perceptual
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1183
      ImageHeight: 1738
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: Perceptual
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1183
      ImageHeight: 2226
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: Perceptual
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1183
      ImageHeight: 1431
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: Perceptual
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1949
      ImageHeight: 1750
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: Perceptual
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1183
      ImageHeight: 1969
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: Perceptual
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1911
      ImageHeight: 1518
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: Perceptual
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1949
      ImageHeight: 1979
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: Perceptual
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1100
      ImageHeight: 90
      ColorSpace: black is zero
      BitsPerSample: 1
      BitsPerSampleUnit: integer
     Filter: FlateDecode
   Fonts: 
    Type1: 
     Font: 
      BaseFont: FPGKIO+AdvTTb5929f4c+20
      FontSubset: true
      FirstChar: 2
      LastChar: 151
      FontDescriptor: 
       FontName: FPGKIO+AdvTTb5929f4c+20
       Flags: Symbolic
       FontBBox: -447, -208, 1375, 864
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: FPFEPL+AdvTTb5929f4c
      FontSubset: true
      FirstChar: 32
      LastChar: 243
      FontDescriptor: 
       FontName: FPFEPL+AdvTTb5929f4c
       Flags: Nonsymbolic
       FontBBox: -41, -250, 812, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: FPFFCL+AdvTT99c4c969
      FontSubset: true
      FirstChar: 32
      LastChar: 121
      FontDescriptor: 
       FontName: FPFFCL+AdvTT99c4c969
       Flags: Nonsymbolic
       FontBBox: -41, -250, 854, 885
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: FPKJMB+AdvTTaf7f9f4f.B+20
      FontSubset: true
      FirstChar: 32
      LastChar: 146
      FontDescriptor: 
       FontName: FPKJMB+AdvTTaf7f9f4f.B+20
       Flags: Nonsymbolic
       FontBBox: -468, -197, 1656, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: FPKJFP+AdvTT8861b38f.I
      FontSubset: true
      FirstChar: 32
      LastChar: 115
      FontDescriptor: 
       FontName: FPKJFP+AdvTT8861b38f.I
       Flags: Nonsymbolic
       FontBBox: -187, -239, 1062, 875
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: FPFGCI+AdvTT86d47313
      FontSubset: true
      FirstChar: 32
      LastChar: 197
      FontDescriptor: 
       FontName: FPFGCI+AdvTT86d47313
       Flags: Serif, Nonsymbolic
       FontBBox: -20, -239, 1020, 875
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: FPFGCJ+AdvTT86d47313+20
      FontSubset: true
      FirstChar: 2
      LastChar: 151
      FontDescriptor: 
       FontName: FPFGCJ+AdvTT86d47313+20
       Flags: Symbolic
       FontBBox: -354, -218, 1291, 812
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: FPHPIO+AdvTT1b53b5fb.I
      FontSubset: true
      FirstChar: 32
      LastChar: 121
      FontDescriptor: 
       FontName: FPHPIO+AdvTT1b53b5fb.I
       Flags: Nonsymbolic
       FontBBox: -114, -250, 864, 854
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: FPFGDK+AdvTT86d47313+03
      FontSubset: true
      FirstChar: 1
      LastChar: 2
      FontDescriptor: 
       FontName: FPFGDK+AdvTT86d47313+03
       Flags: Symbolic
       FontBBox: -364, -250, 906, 885
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: FPFDHD+AdvTTaf7f9f4f.B
      FontSubset: true
      FirstChar: 32
      LastChar: 121
      FontDescriptor: 
       FontName: FPFDHD+AdvTTaf7f9f4f.B
       Flags: Nonsymbolic
       FontBBox: -31, -250, 875, 895
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: FPKJIB+AdvTT99c4c969+20
      FontSubset: true
      FirstChar: 32
      LastChar: 146
      FontDescriptor: 
       FontName: FPKJIB+AdvTT99c4c969+20
       Flags: Nonsymbolic
       FontBBox: -447, -197, 1583, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: FPFEPK+AdvTTe45e47d2
      FontSubset: true
      FirstChar: 32
      LastChar: 122
      FontDescriptor: 
       FontName: FPFEPK+AdvTTe45e47d2
       Flags: Nonsymbolic
       FontBBox: -41, -250, 833, 875
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MyriadPro-Regular
      FirstChar: 1
      LastChar: 255
      FontDescriptor: 
       FontName: MyriadPro-Regular
       Flags: Nonsymbolic
       FontBBox: -157, -250, 1126, 952
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: FPILBI+AdvTT83913201.I
      FontSubset: true
      FirstChar: 32
      LastChar: 121
      FontDescriptor: 
       FontName: FPILBI+AdvTT83913201.I
       Flags: Nonsymbolic
       FontBBox: -93, -250, 906, 875
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: FPKJGA+AdvTT86d47313+22
      FontSubset: true
      FirstChar: 1
      LastChar: 2
      FontDescriptor: 
       FontName: FPKJGA+AdvTT86d47313+22
       Flags: Symbolic
       FontBBox: -166, -250, 1031, 864
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: FPFFOI+AdvTT7329fd89.I
      FontSubset: true
      FirstChar: 32
      LastChar: 121
      FontDescriptor: 
       FontName: FPFFOI+AdvTT7329fd89.I
       Flags: Nonsymbolic
       FontBBox: -104, -250, 885, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: FPKJIA+AdvTTb5929f4c+03
      FontSubset: true
      FirstChar: 1
      LastChar: 2
      FontDescriptor: 
       FontName: FPKJIA+AdvTTb5929f4c+03
       Flags: Symbolic
       FontBBox: -531, -260, 802, 968
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
   XMP: <x:xmpmeta x:xmptk="Adobe XMP Core 5.2-c001 63.139439, 2010/09/27-13:37:26        " xmlns:x="adobe:ns:meta/">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about="" xmlns:pdf="http://ns.adobe.com/pdf/1.3/">
         <pdf:Keywords>Olfactory receptors,OR,Natural variants,Mutations,7-TM receptors,G protein-coupled receptor,GPCR,Sensegenomics,Database</pdf:Keywords>
         <pdf:Producer>Acrobat Distiller 10.0.0 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version)</pdf:Producer>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:dc="http://purl.org/dc/elements/1.1/">
         <dc:format>application/pdf</dc:format>
         <dc:identifier>10.1186/s12915-021-00962-0</dc:identifier>
         <dc:publisher>
            <rdf:Bag>
               <rdf:li>BMC Biology</rdf:li>
            </rdf:Bag>
         </dc:publisher>
         <dc:description>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">BMC Biology, 2021, doi:10.1186/s12915-021-00962-0</rdf:li>
            </rdf:Alt>
         </dc:description>
         <dc:subject>
            <rdf:Bag>
               <rdf:li>Olfactory receptors</rdf:li>
               <rdf:li>OR</rdf:li>
               <rdf:li>Natural variants</rdf:li>
               <rdf:li>Mutations</rdf:li>
               <rdf:li>7-TM receptors</rdf:li>
               <rdf:li>G protein-coupled receptor</rdf:li>
               <rdf:li>GPCR</rdf:li>
               <rdf:li>Sensegenomics</rdf:li>
               <rdf:li>Database</rdf:li>
            </rdf:Bag>
         </dc:subject>
         <dc:title>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">The mutational landscape of human olfactory G protein-coupled receptors</rdf:li>
            </rdf:Alt>
         </dc:title>
         <dc:creator>
            <rdf:Seq>
               <rdf:li>Ramón Cierco Jimenez</rdf:li>
               <rdf:li>Nil Casajuana-Martin</rdf:li>
               <rdf:li>Adrián García-Recio</rdf:li>
               <rdf:li>Lidia Alcántara</rdf:li>
               <rdf:li>Leonardo Pardo</rdf:li>
               <rdf:li>Mercedes Campillo</rdf:li>
               <rdf:li>Angel Gonzalez</rdf:li>
            </rdf:Seq>
         </dc:creator>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:xmp="http://ns.adobe.com/xap/1.0/">
         <xmp:ModifyDate>2021-02-05T17:50:16+01:00</xmp:ModifyDate>
         <xmp:MetadataDate>2021-02-05T17:50:16+01:00</xmp:MetadataDate>
         <xmp:CreateDate>2021-02-02T16:42:32+08:00</xmp:CreateDate>
         <xmp:CreatorTool>Arbortext Advanced Print Publisher 9.1.440/W Unicode</xmp:CreatorTool>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:stEvt="http://ns.adobe.com/xap/1.0/sType/ResourceEvent#" xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/">
         <xmpMM:DocumentID>uuid:a0d687a4-b0dc-4033-86e7-6f03110ae9d2</xmpMM:DocumentID>
         <xmpMM:InstanceID>uuid:41f19436-0eda-4513-91b4-18bd3fa52058</xmpMM:InstanceID>
         <xmpMM:RenditionClass>default</xmpMM:RenditionClass>
         <xmpMM:VersionID>1</xmpMM:VersionID>
         <xmpMM:History>
            <rdf:Seq>
               <rdf:li rdf:parseType="Resource">
                  <stEvt:action>converted</stEvt:action>
                  <stEvt:instanceID>uuid:a0d687a4-b0dc-4033-86e7-6f03110ae9d2</stEvt:instanceID>
                  <stEvt:parameters>converted to PDF/A-2b</stEvt:parameters>
                  <stEvt:softwareAgent>pdfToolbox</stEvt:softwareAgent>
                  <stEvt:when>2021-02-04T23:27:26+08:00</stEvt:when>
               </rdf:li>
            </rdf:Seq>
         </xmpMM:History>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:pdfaid="http://www.aiim.org/pdfa/ns/id/">
         <pdfaid:part>2</pdfaid:part>
         <pdfaid:conformance>B</pdfaid:conformance>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:author="http://springernature.com/ns/xmpExtensions/2.0/authorInfo/" xmlns:sn="http://springernature.com/ns/xmpExtensions/2.0/">
         <sn:authorInfo>
            <rdf:Bag>
               <rdf:li rdf:parseType="Resource">
                  <author:name>Angel Gonzalez</author:name>
                  <author:orcid>http://orcid.org/0000-0002-2284-8307</author:orcid>
               </rdf:li>
            </rdf:Bag>
         </sn:authorInfo>
      </rdf:Description>
      <rdf:Description rdf:about="" xmlns:pdfaExtension="http://www.aiim.org/pdfa/ns/extension/" xmlns:pdfaField="http://www.aiim.org/pdfa/ns/field#" xmlns:pdfaProperty="http://www.aiim.org/pdfa/ns/property#" xmlns:pdfaSchema="http://www.aiim.org/pdfa/ns/schema#" xmlns:pdfaType="http://www.aiim.org/pdfa/ns/type#">
         <pdfaExtension:schemas>
            <rdf:Bag>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:schema>Springer Nature ORCID Schema</pdfaSchema:schema>
                  <pdfaSchema:namespaceURI>http://springernature.com/ns/xmpExtensions/2.0/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>sn</pdfaSchema:prefix>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:name>authorInfo</pdfaProperty:name>
                           <pdfaProperty:valueType>Bag AuthorInformation</pdfaProperty:valueType>
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Author information: contains the name of each author and his/her ORCID (ORCiD: Open Researcher and Contributor ID). An ORCID is a persistent identifier (a non-proprietary alphanumeric code) to uniquely identify scientific and other academic authors.</pdfaProperty:description>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:name>editorInfo</pdfaProperty:name>
                           <pdfaProperty:valueType>Bag EditorInformation</pdfaProperty:valueType>
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Editor information: contains the name of each editor and his/her ORCID identifier.</pdfaProperty:description>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:name>seriesEditorInfo</pdfaProperty:name>
                           <pdfaProperty:valueType>Bag SeriesEditorInformation</pdfaProperty:valueType>
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Series editor information: contains the name of each series editor and his/her ORCID identifier.</pdfaProperty:description>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
                  <pdfaSchema:valueType>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaType:type>AuthorInformation</pdfaType:type>
                           <pdfaType:namespaceURI>http://springernature.com/ns/xmpExtensions/2.0/authorInfo/</pdfaType:namespaceURI>
                           <pdfaType:prefix>author</pdfaType:prefix>
                           <pdfaType:description>Specifies the types of author information: name and ORCID of an author.</pdfaType:description>
                           <pdfaType:field>
                              <rdf:Seq>
                                 <rdf:li rdf:parseType="Resource">
                                    <pdfaField:name>name</pdfaField:name>
                                    <pdfaField:valueType>Text</pdfaField:valueType>
                                    <pdfaField:description>Gives the name of an author.</pdfaField:description>
                                 </rdf:li>
                                 <rdf:li rdf:parseType="Resource">
                                    <pdfaField:name>orcid</pdfaField:name>
                                    <pdfaField:valueType>URI</pdfaField:valueType>
                                    <pdfaField:description>Gives the ORCID of an author.</pdfaField:description>
                                 </rdf:li>
                              </rdf:Seq>
                           </pdfaType:field>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaType:type>EditorInformation</pdfaType:type>
                           <pdfaType:namespaceURI>http://springernature.com/ns/xmpExtensions/2.0/editorInfo/</pdfaType:namespaceURI>
                           <pdfaType:prefix>editor</pdfaType:prefix>
                           <pdfaType:description>Specifies the types of editor information: name and ORCID of an editor.</pdfaType:description>
                           <pdfaType:field>
                              <rdf:Seq>
                                 <rdf:li rdf:parseType="Resource">
                                    <pdfaField:name>name</pdfaField:name>
                                    <pdfaField:valueType>Text</pdfaField:valueType>
                                    <pdfaField:description>Gives the name of an editor.</pdfaField:description>
                                 </rdf:li>
                                 <rdf:li rdf:parseType="Resource">
                                    <pdfaField:name>orcid</pdfaField:name>
                                    <pdfaField:valueType>URI</pdfaField:valueType>
                                    <pdfaField:description>Gives the ORCID of an editor.</pdfaField:description>
                                 </rdf:li>
                              </rdf:Seq>
                           </pdfaType:field>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaType:type>SeriesEditorInformation</pdfaType:type>
                           <pdfaType:namespaceURI>http://springernature.com/ns/xmpExtensions/2.0/seriesEditorInfo/</pdfaType:namespaceURI>
                           <pdfaType:prefix>seriesEditor</pdfaType:prefix>
                           <pdfaType:description>Specifies the types of series editor information: name and ORCID of a series editor.</pdfaType:description>
                           <pdfaType:field>
                              <rdf:Seq>
                                 <rdf:li rdf:parseType="Resource">
                                    <pdfaField:name>name</pdfaField:name>
                                    <pdfaField:valueType>Text</pdfaField:valueType>
                                    <pdfaField:description>Gives the name of a series editor.</pdfaField:description>
                                 </rdf:li>
                                 <rdf:li rdf:parseType="Resource">
                                    <pdfaField:name>orcid</pdfaField:name>
                                    <pdfaField:valueType>URI</pdfaField:valueType>
                                    <pdfaField:description>Gives the ORCID of a series editor.</pdfaField:description>
                                 </rdf:li>
                              </rdf:Seq>
                           </pdfaType:field>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:valueType>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/pdf/1.3/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdf</pdfaSchema:prefix>
                  <pdfaSchema:schema>Adobe PDF Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>A name object indicating whether the document has been modified to include trapping information</pdfaProperty:description>
                           <pdfaProperty:name>Trapped</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/xap/1.0/mm/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>xmpMM</pdfaSchema:prefix>
                  <pdfaSchema:schema>XMP Media Management Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>UUID based identifier for specific incarnation of a document</pdfaProperty:description>
                           <pdfaProperty:name>InstanceID</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>The common identifier for all versions and renditions of a document.</pdfaProperty:description>
                           <pdfaProperty:name>OriginalDocumentID</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>A reference to the original document from which this one is derived. It is a minimal reference; missing components can be assumed to be unchanged. For example, a new version might only need to specify the instance ID and version number of the previous version, or a rendition might only need to specify the instance ID and rendition class of the original.</pdfaProperty:description>
                           <pdfaProperty:name>DerivedFrom</pdfaProperty:name>
                           <pdfaProperty:valueType>ResourceRef</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
                  <pdfaSchema:valueType>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaType:description>Identifies a portion of a document. This can be a position at which the document has been changed since the most recent event history (stEvt:changed). For a resource within an xmpMM:Ingredients list, the ResourceRef uses this type to identify both the portion of the containing document that refers to the resource, and the portion of the referenced resource that is referenced.</pdfaType:description>
                           <pdfaType:namespaceURI>http://ns.adobe.com/xap/1.0/sType/Part#</pdfaType:namespaceURI>
                           <pdfaType:prefix>stPart</pdfaType:prefix>
                           <pdfaType:type>Part</pdfaType:type>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:valueType>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/xap/1.0/t/pg/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>xmpTPg</pdfaSchema:prefix>
                  <pdfaSchema:schema>XMP Paged-Text</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>A structure containing the characteristics of a font used in a document</pdfaProperty:description>
                           <pdfaProperty:name>Fonts</pdfaProperty:name>
                           <pdfaProperty:valueType>Bag Font</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>XMP08 Spec: An ordered array of plate names that are needed to print the document (including any in contained documents).</pdfaProperty:description>
                           <pdfaProperty:name>PlateNames</pdfaProperty:name>
                           <pdfaProperty:valueType>Seq Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
                  <pdfaSchema:valueType>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaType:description>A structure containing the characteristics of a font used in a document.</pdfaType:description>
                           <pdfaType:namespaceURI>http://ns.adobe.com/xap/1.0/sType/Font#</pdfaType:namespaceURI>
                           <pdfaType:prefix>stFnt</pdfaType:prefix>
                           <pdfaType:type>Font</pdfaType:type>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:valueType>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/pdfx/1.3/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdfx</pdfaSchema:prefix>
                  <pdfaSchema:schema>Adobe Document Info PDF eXtension Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>ID of PDF/X standard</pdfaProperty:description>
                           <pdfaProperty:name>GTS_PDFXVersion</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Conformance level of PDF/X standard</pdfaProperty:description>
                           <pdfaProperty:name>GTS_PDFXConformance</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Company creating the PDF</pdfaProperty:description>
                           <pdfaProperty:name>Company</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Date when document was last modified</pdfaProperty:description>
                           <pdfaProperty:name>SourceModified</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://www.aiim.org/pdfa/ns/id/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdfaid</pdfaSchema:prefix>
                  <pdfaSchema:schema>PDF/A ID Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Part of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>part</pdfaProperty:name>
                           <pdfaProperty:valueType>Integer</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Amendment of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>amd</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Conformance level of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>conformance</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
            </rdf:Bag>
         </pdfaExtension:schemas>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Sequence: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 496, 635, 538, 677
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 234, 585, 243, 594
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 400, 73, 518, 80
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 338, 65, 477, 72
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 114, 165, 184, 172
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
    Page: 
     Sequence: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 261, 645, 266, 654
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 105, 609, 110, 618
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 115, 609, 120, 618
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 118, 585, 123, 594
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 90, 537, 95, 546
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 99, 537, 104, 546
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 242, 477, 247, 486
       Flags: Print
       AppearanceDictionary: true
       Destination: 96
      Annotation: 
       Subtype: Link
       Rect: 255, 477, 260, 486
       Flags: Print
       AppearanceDictionary: true
       Destination: 96
      Annotation: 
       Subtype: Link
       Rect: 193, 441, 198, 450
       Flags: Print
       AppearanceDictionary: true
       Destination: 96
      Annotation: 
       Subtype: Link
       Rect: 233, 417, 242, 426
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 160, 393, 170, 402
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 175, 393, 185, 402
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 160, 357, 170, 366
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 176, 357, 186, 366
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 157, 285, 167, 294
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 172, 285, 182, 294
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 260, 285, 270, 294
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 275, 285, 285, 294
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 159, 261, 169, 270
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 175, 261, 185, 270
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 91, 201, 100, 210
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 87, 57, 97, 66
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 103, 57, 112, 66
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 400, 657, 410, 666
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 415, 657, 425, 666
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 469, 597, 479, 606
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 485, 597, 495, 606
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 457, 585, 467, 594
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 474, 585, 484, 594
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 523, 549, 533, 558
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 369, 321, 374, 330
       Flags: Print
       AppearanceDictionary: true
       Destination: 10
      Annotation: 
       Subtype: Link
       Rect: 425, 321, 435, 330
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 391, 297, 396, 306
       Flags: Print
       AppearanceDictionary: true
       Destination: 172
      Annotation: 
       Subtype: Link
       Rect: 474, 273, 479, 282
       Flags: Print
       AppearanceDictionary: true
       Destination: 392
      Annotation: 
       Subtype: Link
       Rect: 531, 177, 536, 186
       Flags: Print
       AppearanceDictionary: true
       Destination: 10
      Annotation: 
       Subtype: Link
       Rect: 427, 141, 432, 150
       Flags: Print
       AppearanceDictionary: true
       Destination: 96
      Annotation: 
       Subtype: Link
       Rect: 437, 141, 447, 150
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 463, 81, 468, 90
       Flags: Print
       AppearanceDictionary: true
       Destination: 175
     Thumb: true
    Page: 
     Sequence: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 215, 297, 220, 306
       Flags: Print
       AppearanceDictionary: true
       Destination: 175
      Annotation: 
       Subtype: Link
       Rect: 79, 249, 84, 258
       Flags: Print
       AppearanceDictionary: true
       Destination: 175
      Annotation: 
       Subtype: Link
       Rect: 283, 165, 288, 174
       Flags: Print
       AppearanceDictionary: true
       Destination: 10
      Annotation: 
       Subtype: Link
       Rect: 523, 273, 533, 282
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 325, 237, 330, 246
       Flags: Print
       AppearanceDictionary: true
       Destination: 457
      Annotation: 
       Subtype: Link
       Rect: 412, 237, 416, 246
       Flags: Print
       AppearanceDictionary: true
       Destination: 10
      Annotation: 
       Subtype: Link
       Rect: 468, 237, 477, 246
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 473, 69, 478, 78
       Flags: Print
       AppearanceDictionary: true
       Destination: 457
     Thumb: true
    Page: 
     Sequence: 4
     Thumb: true
    Page: 
     Sequence: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 164, 153, 169, 162
       Flags: Print
       AppearanceDictionary: true
       Destination: 172
      Annotation: 
       Subtype: Link
       Rect: 173, 117, 178, 126
       Flags: Print
       AppearanceDictionary: true
       Destination: 179
      Annotation: 
       Subtype: Link
       Rect: 458, 177, 463, 186
       Flags: Print
       AppearanceDictionary: true
       Destination: 10
      Annotation: 
       Subtype: Link
       Rect: 359, 105, 364, 114
       Flags: Print
       AppearanceDictionary: true
       Destination: 199
      Annotation: 
       Subtype: Link
       Rect: 327, 81, 332, 90
       Flags: Print
       AppearanceDictionary: true
       Destination: 199
     Thumb: true
    Page: 
     Sequence: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 260, 69, 270, 78
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 275, 69, 285, 78
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 375, 69, 385, 78
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 391, 69, 400, 78
       Flags: Print
       AppearanceDictionary: true
       Destination: null
     Thumb: true
    Page: 
     Sequence: 7
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 156, 261, 166, 270
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 128, 201, 138, 210
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 106, 129, 116, 138
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 233, 81, 238, 90
       Flags: Print
       AppearanceDictionary: true
       Destination: 206
      Annotation: 
       Subtype: Link
       Rect: 370, 261, 379, 270
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 385, 261, 395, 270
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 385, 225, 394, 234
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 399, 225, 409, 234
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 327, 153, 332, 162
       Flags: Print
       AppearanceDictionary: true
       Destination: 206
      Annotation: 
       Subtype: Link
       Rect: 411, 153, 416, 162
       Flags: Print
       AppearanceDictionary: true
       Destination: 10
      Annotation: 
       Subtype: Link
       Rect: 475, 153, 485, 162
       Flags: Print
       AppearanceDictionary: true
       Destination: null
     Thumb: true
    Page: 
     Sequence: 8
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 106, 57, 111, 66
       Flags: Print
       AppearanceDictionary: true
       Destination: 10
      Annotation: 
       Subtype: Link
       Rect: 371, 105, 376, 114
       Flags: Print
       AppearanceDictionary: true
       Destination: 10
      Annotation: 
       Subtype: Link
       Rect: 363, 242, 390, 250
       Flags: Print
       AppearanceDictionary: true
       Destination: null
     Thumb: true
    Page: 
     Sequence: 9
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 129, 69, 139, 78
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 145, 69, 155, 78
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 161, 69, 171, 78
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 199, 69, 204, 78
       Flags: Print
       AppearanceDictionary: true
       Destination: 106
      Annotation: 
       Subtype: Link
       Rect: 379, 105, 389, 114
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 370, 57, 375, 66
       Flags: Print
       AppearanceDictionary: true
       Destination: 10
     Thumb: true
    Page: 
     Sequence: 10
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 119, 165, 129, 174
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 161, 165, 166, 174
       Flags: Print
       AppearanceDictionary: true
       Destination: 106
      Annotation: 
       Subtype: Link
       Rect: 135, 129, 145, 138
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 275, 93, 285, 102
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 156, 57, 166, 66
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 344, 177, 353, 186
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 379, 177, 384, 186
       Flags: Print
       AppearanceDictionary: true
       Destination: 106
      Annotation: 
       Subtype: Link
       Rect: 492, 153, 501, 162
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 516, 105, 526, 114
       Flags: Print
       AppearanceDictionary: true
       Destination: null
     Thumb: true
    Page: 
     Sequence: 11
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 112, 105, 122, 114
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 127, 105, 137, 114
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 143, 105, 153, 114
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 179, 105, 184, 114
       Flags: Print
       AppearanceDictionary: true
       Destination: 106
     Thumb: true
    Page: 
     Sequence: 12
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 227, 621, 232, 630
       Flags: Print
       AppearanceDictionary: true
       Destination: 113
      Annotation: 
       Subtype: Link
       Rect: 275, 609, 280, 618
       Flags: Print
       AppearanceDictionary: true
       Destination: 113
      Annotation: 
       Subtype: Link
       Rect: 174, 525, 179, 534
       Flags: Print
       AppearanceDictionary: true
       Destination: 113
      Annotation: 
       Subtype: Link
       Rect: 183, 477, 188, 486
       Flags: Print
       AppearanceDictionary: true
       Destination: 113
      Annotation: 
       Subtype: Link
       Rect: 87, 117, 97, 126
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 525, 681, 535, 690
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 447, 621, 457, 630
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 486, 585, 496, 594
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 452, 561, 462, 570
       Flags: Print
       AppearanceDictionary: true
       Destination: 330
      Annotation: 
       Subtype: Link
       Rect: 461, 549, 470, 558
       Flags: Print
       AppearanceDictionary: true
       Destination: 330
      Annotation: 
       Subtype: Link
       Rect: 468, 477, 478, 486
       Flags: Print
       AppearanceDictionary: true
       Destination: 330
      Annotation: 
       Subtype: Link
       Rect: 398, 393, 408, 402
       Flags: Print
       AppearanceDictionary: true
       Destination: 330
     Thumb: true
    Page: 
     Sequence: 13
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 248, 525, 257, 534
       Flags: Print
       AppearanceDictionary: true
       Destination: 330
      Annotation: 
       Subtype: Link
       Rect: 115, 417, 125, 426
       Flags: Print
       AppearanceDictionary: true
       Destination: 330
      Annotation: 
       Subtype: Link
       Rect: 131, 417, 141, 426
       Flags: Print
       AppearanceDictionary: true
       Destination: 330
      Annotation: 
       Subtype: Link
       Rect: 223, 405, 290, 414
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 56, 393, 133, 402
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 240, 345, 245, 354
       Flags: Print
       AppearanceDictionary: true
       Destination: 10
      Annotation: 
       Subtype: Link
       Rect: 59, 333, 69, 342
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 137, 297, 239, 306
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 146, 237, 151, 246
       Flags: Print
       AppearanceDictionary: true
       Destination: 10
      Annotation: 
       Subtype: Link
       Rect: 124, 141, 129, 150
       Flags: Print
       AppearanceDictionary: true
       Destination: 10
      Annotation: 
       Subtype: Link
       Rect: 155, 69, 164, 78
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 395, 669, 400, 678
       Flags: Print
       AppearanceDictionary: true
       Destination: 10
      Annotation: 
       Subtype: Link
       Rect: 451, 669, 460, 678
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 461, 606, 466, 616
       Flags: Print
       AppearanceDictionary: true
       Destination: 10
      Annotation: 
       Subtype: Link
       Rect: 523, 606, 533, 616
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 485, 546, 490, 556
       Flags: Print
       AppearanceDictionary: true
       Destination: 10
      Annotation: 
       Subtype: Link
       Rect: 365, 534, 370, 544
       Flags: Print
       AppearanceDictionary: true
       Destination: 10
      Annotation: 
       Subtype: Link
       Rect: 414, 498, 419, 508
       Flags: Print
       AppearanceDictionary: true
       Destination: 10
      Annotation: 
       Subtype: Link
       Rect: 531, 498, 536, 508
       Flags: Print
       AppearanceDictionary: true
       Destination: 10
      Annotation: 
       Subtype: Link
       Rect: 394, 450, 404, 460
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 461, 363, 466, 373
       Flags: Print
       AppearanceDictionary: true
       Destination: 172
      Annotation: 
       Subtype: Link
       Rect: 528, 363, 533, 373
       Flags: Print
       AppearanceDictionary: true
       Destination: 96
      Annotation: 
       Subtype: Link
       Rect: 417, 327, 538, 337
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 304, 315, 342, 325
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 491, 291, 538, 301
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 304, 279, 376, 289
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 499, 244, 531, 251
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 304, 235, 402, 242
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
    Page: 
     Sequence: 14
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 266, 672, 270, 679
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 126, 561, 130, 568
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 100, 197, 104, 204
       Flags: Print
       AppearanceDictionary: true
       Destination: 10
      Annotation: 
       Subtype: Link
       Rect: 100, 188, 104, 195
       Flags: Print
       AppearanceDictionary: true
       Destination: 10
      Annotation: 
       Subtype: Link
       Rect: 270, 188, 274, 195
       Flags: Print
       AppearanceDictionary: true
       Destination: 96
      Annotation: 
       Subtype: Link
       Rect: 58, 170, 171, 177
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 56, 152, 138, 159
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
    Page: 
     Sequence: 15
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 319, 549, 515, 557
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 401, 306, 525, 314
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 319, 297, 432, 305
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
  Checksum: ef4c11eb
   Type: CRC32
  Checksum: 1cd839062776ad08b407bc3ff2b0c44f
   Type: MD5
  Checksum: 8bcf6ece102cac8b3c9386b21e35b2900a6661f7
   Type: SHA-1