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'bm_CR64' cannot be found Offset: 614964 MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 628 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Recommendations from the European Commission Initiative on Breast Cancer for multigene testing to guide the use of adjuvant ch攀洀漀琀栀攀爀愀瀀礀 椀渀 瀀愀琀椀攀渀琀猀 眀椀琀栀 攀愀爀氀礀 戀爀攀愀猀琀 挀愀渀挀攀爀Ⰰ 栀漀爀洀漀渀攀 爀攀挀攀瀀琀漀爀 瀀漀猀椀琀椀瘀攀Ⰰ 䠀䔀刀ⴀ㈀ 渀攀最愀琀椀瘀攩㸾൥湤潢樍㔹ㄠ〠潢樍㰼⽃嬰⸰‰⸰‰⸰崯䍯畮琠〯䑥獴⣾＀䄀ㄩ⽆‰⽎數琠㘰㌠〠刯偡牥湴‵㤰‰⁒⽔楴汥⣾＀䈀愀挀欀最爀漀甀渀搩㸾൥湤潢樍㔹㈠〠潢樍㰼⽃嬰⸰‰⸰‰⸰崯䍯畮琠〯䑥獴⣾＀䄀㠩⽆‰⽐慲敮琠㔹〠〠刯偲敶‵㤳‰⁒⽔楴汥⣾＀刀攀昀攀爀攀渀挀攀猩㸾൥湤潢樍㔹㌠〠潢樍㰼⽃嬰⸰‰⸰‰⸰崯䍯畮琠〯䑥獴⣾＀䴀ㄩ⽆‰⽎數琠㔹㈠〠刯偡牥湴‵㤰‰⁒⽐牥瘠㔹㐠〠刯呩瑬攨ADDITIONAL INFORMATION Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Children: Item: Title: Background Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Children: Item: Title: Structured question and outcome prioritisation Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: Systematic review Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Children: Item: Title: Data sources and searches Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: Study selection Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: Data extraction and risk of bias assessment Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: Data analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: Certainty of the evidence Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: Comparison scenarios and modelling Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: Evidence to decision and recommendation formulation Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Children: Item: Title: Included studies Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: 21 gene recurrence score Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Children: Item: Title: Treatment interaction design studies Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: Marker-based strategy Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: 70-GS Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Children: Item: Title: Treatment interaction design studies Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7 Item: Title: Marker-based strategy Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cbd213e Item: Title: Modelling for predicting impact of testing on patient’s outcomes Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247 Item: Title: Results from the systematic review of economic evidence Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3ecd23d9 Item: Title: Certainty of evidence Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@569cfc36 Item: Title: Evidence to decision frameworks Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@43bd930a Children: Item: Title: 21-RS Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@33723e30 Item: Title: 70-GS Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@64f6106c Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@553a3d88 Children: Item: Title: Statement of principal findings Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a30d1e6 Item: Title: Strengths and weaknesses of the study Destination: 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from the European Commission Initiative on Breast Cancer for multigene testing to guide the use of adjuvant chemotherapy in patients with early breast cancer, hormone receptor positive, HER-2 negative Paolo Giorgi Rossi Annette Lebeau Carlos Canelo-Aybar Zuleika Saz-Parkinson Cecily Quinn Miranda Langendam Helen Mcgarrigle Sue Warman David Rigau Pablo Alonso-Coello Mireille Broeders Axel Graewingholt Margarita Posso Stephen Duffy Holger J. Schünemann Mariangela Autelitano Bettina Borisch Xavier Castells Edoardo Colzani Jan Daneš Patricia Fitzpatrick Livia Giordano Solveig Hofvind Lydia Ioannidou-Mouzaka Susan Knox Lennarth Nystrom Elena Parmelli Elsa Perez Alberto Torresin Ruben Van Engen Cary Van Landsveld-Verhoeven Ken Young Springer US British Journal of Cancer, doi:10.1038/s41416-020-01247-z 10.1038/s41416-020-01247-z http://dx.doi.org/10.1038/s41416-020-01247-z journal British Journal of Cancer © 2021, The Author(s) 1532-1827 10.1038/s41416-020-01247-z springer.com springerlink.com 2010-04-23 True 10.1038/s41416-020-01247-z springer.com springerlink.com Springer 2021-04-14T14:35:33+05:30 2021-04-14T14:34:14+05:30 2021-04-14T14:35:33+05:30 True VoR uuid:f1a6b8d8-e308-4bcf-a5a1-9eed0607ae06 uuid:99001876-4bee-4897-93ed-39dd54a91722 default 1 converted uuid:782b3240-f495-44eb-b849-c8d5b7ba7535 converted to PDF/A-2b pdfToolbox 2021-04-14T14:35:33+05:30 2 B Zuleika Saz-Parkinson http://orcid.org/0000-0002-3518-5899 Stephen Duffy http://orcid.org/0000-0003-4901-7922 http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/pdfx/1.3/ pdfx pdfx internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text external Mirrors crossmark:CrosMarkDomains CrossMarkDomains Seq Text internal Mirrors crossmark:DOI doi Text http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. 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