badc6f18ba75adebb87c959fa09368d9 pmc_33708133.pdf 4bbb0a3f83fe921e29082e55cc2f17482d69370d pmc_33708133.pdf ca5971dad3cb444d98a849f2aefca1212d1f83b8ca5a91ba70f3c4b424d6fe8f pmc_33708133.pdf Title: Estimating Central Pulse Pressure From Blood Flow by Identifying the Main Physical Determinants of Pulse Pressure Amplification Subject: Several studies suggest that central (aortic) blood pressure (cBP) is a better marker of cardiovascular disease risk than peripheral blood pressure (pBP). Keywords: pulse pressure amplification, 1-D model, peripheral pressure, central pressure, analytical solutions, hemodynamics Author: Joaquín Flores Gerónimo Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Wed Feb 17 15:13:56 2021 CET ModDate: Wed Feb 17 17:01:15 2021 CET Custom Metadata: no Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 15 Encrypted: no Page size: 595.26 x 779.52 pts Page rot: 0 File size: 2819545 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- TCPYQH+HelveticaNeueLTStd-Bd Type 1C Custom yes yes no 40 0 DHULIA+HelveticaNeueLTStd-Lt Type 1C Custom yes yes no 45 0 CADDPG+HelveticaNeueLTStd-BdIt Type 1C WinAnsi yes yes no 58 0 AMCSMZ+HelveticaNeueLTStd-LtIt Type 1C Custom yes yes no 60 0 BDYFXR+HelveticaNeueLTStd-MdIt Type 1C WinAnsi yes yes no 65 0 YWZNEF+RMTMI Type 1C Custom yes yes yes 67 0 IFSXUE+MTSY Type 1C Custom yes yes yes 69 0 BRLHOV+MinionPro-Regular Type 1C Custom yes yes no 71 0 WVKAII+MinionPro-Bold Type 1C Custom yes yes no 114 0 IHJMPC+MinionPro-It Type 1C WinAnsi yes yes no 176 0 SHCJJT+MTSYB Type 1C Custom yes yes no 195 0 AMPSZQ+CMR7 Type 1C WinAnsi yes yes no 197 0 AQVZXN+MTEX Type 1C Custom yes yes no 199 0 ZHVUBQ+HelveticaNeueLTStd-Md Type 1C Custom yes yes no 235 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-10-02 03:27:38 CEST RepresentationInformation: pmc_33708133.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2023-03-31 12:09:09 CEST Size: 2819545 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 519 FreeObjects: 22 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: Estimating Central Pulse Pressure From Blood Flow by Identifying the Main Physical Determinants of Pulse Pressure Amplification Destination: ariclecounter.1 Children: Item: Title: 1. Introduction Destination: section.0.1 Item: Title: 2. Materials and Methods Destination: section.0.2 Children: Item: Title: 2.1. In vivo Data Destination: subsection.0.2.1 Item: Title: 2.2. Dataset of in silico Pulse Waves Destination: subsection.0.2.2 Item: Title: 2.3. Blood Flow Models Destination: subsection.0.2.3 Children: Item: Title: 2.3.1. Single-Vessel Model Destination: subsubsection.0.2.3.1 Item: Title: 2.3.2. Approximate Amplification Term Destination: subsubsection.0.2.3.2 Item: Title: 2.4. Methodology for Estimating cPP Destination: subsection.0.2.4 Children: Item: Title: 2.4.1. Method 1 Destination: subsubsection.0.2.4.1 Item: Title: 2.4.2. Method 2 Destination: subsubsection.0.2.4.2 Item: Title: 3. Results Destination: section.0.3 Children: Item: Title: 3.1. Approximate Pressure Calculations Using the Single-Vessel Model Destination: subsection.0.3.1 Item: Title: 3.2. In silico Verification of cPP Estimation Methods Destination: subsection.0.3.2 Item: Title: 3.3. In vivo Verification of cPP Estimation Methods Destination: subsection.0.3.3 Item: Title: 4. Discussion Destination: section.0.4 Children: Item: Title: 4.1. Main Cardiovascular Determinants of Pulse Pressure Amplification Destination: subsection.0.4.1 Item: Title: 4.2. Aging and Pulse Pressure Amplification Destination: subsection.0.4.2 Item: Title: 4.3. Central Pulse Pressure Estimation Methods Destination: subsection.0.4.3 Item: Title: 4.4. Limitations Destination: subsection.0.4.4 Item: Title: 4.5. Perspectives Destination: subsection.0.4.5 Item: Title: 5. Conclusion Destination: section.0.5 Item: Title: Data Availability Statement Destination: section*.23 Item: Title: Author Contributions Destination: section*.24 Item: Title: Funding Destination: section*.25 Item: Title: Acknowledgments Destination: section*.26 Item: Title: Supplementary Material Destination: section*.27 Item: Title: References Destination: section*.28 Info: Title: Estimating Central Pulse Pressure From Blood Flow by Identifying the Main Physical Determinants of Pulse Pressure Amplification Author: Joaquín Flores Gerónimo Subject: Several studies suggest that central (aortic) blood pressure (cBP) is a better marker of cardiovascular disease risk than peripheral blood pressure (pBP). 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Joaquín Flores Gerónimo Estimating Central Pulse Pressure From Blood Flow by Identifying the Main Physical Determinants of Pulse Pressure Amplification pulse pressure amplification 1-D model peripheral pressure central pressure analytical solutions hemodynamics pulse pressure amplification, 1-D model, peripheral pressure, central pressure, analytical solutions, hemodynamics dvips + MiKTeX GPL Ghostscript 9.0 uuid:5a1a9c24-94cd-42fb-9633-255964d179bf uuid:1062197a-7aec-4f91-a727-8cef9710f544 Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 43, 719, 147, 755 Annotation: Subtype: Link Rect: 474, 736, 551, 744 Annotation: Subtype: Link Rect: 463, 728, 505, 736 Annotation: Subtype: Link Rect: 505, 728, 533, 736 Annotation: Subtype: Link Rect: 533, 728, 551, 736 Annotation: Subtype: Link Rect: 450, 720, 551, 728 Annotation: Subtype: Link Rect: 521, 678, 551, 709 Annotation: Subtype: Link Rect: 43, 30, 112, 38 Annotation: Subtype: Link Rect: 116, 30, 176, 38 Annotation: 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External Annotation: Subtype: Link Rect: 108, 248, 149, 258 Destination: External Annotation: Subtype: Link Rect: 238, 216, 289, 227 Destination: External Annotation: Subtype: Link Rect: 43, 204, 64, 216 Destination: External Annotation: Subtype: Link Rect: 47, 156, 81, 166 Destination: External Annotation: Subtype: Link Rect: 204, 124, 263, 135 Destination: External Annotation: Subtype: Link Rect: 267, 124, 287, 135 Destination: External Annotation: Subtype: Link Rect: 123, 78, 169, 90 Destination: External Annotation: Subtype: Link Rect: 171, 78, 191, 90 Destination: External Annotation: Subtype: Link Rect: 307, 697, 398, 708 Destination: External Annotation: Subtype: Link Rect: 401, 697, 421, 708 Destination: External Annotation: Subtype: Link Rect: 448, 605, 471, 617 Destination: External Annotation: Subtype: Link Rect: 473, 605, 493, 617 Destination: External Annotation: Subtype: Link Rect: 327, 594, 378, 605 Destination: External Annotation: Subtype: Link Rect: 380, 594, 400, 605 Destination: External Annotation: Subtype: Link Rect: 480, 548, 522, 559 Destination: External Annotation: Subtype: Link Rect: 525, 548, 546, 559 Destination: External Annotation: Subtype: Link Rect: 307, 514, 348, 525 Destination: External Annotation: Subtype: Link Rect: 352, 514, 377, 525 Destination: External Annotation: Subtype: Link Rect: 382, 514, 437, 525 Destination: External Annotation: Subtype: Link Rect: 442, 514, 462, 525 Destination: External Annotation: Subtype: Link Rect: 467, 514, 501, 525 Destination: External Annotation: Subtype: Link Rect: 505, 514, 525, 525 Destination: External Annotation: Subtype: Link Rect: 307, 422, 361, 433 Destination: External Annotation: Subtype: Link Rect: 363, 422, 383, 433 Destination: External Annotation: Subtype: Link Rect: 397, 273, 427, 281 Destination: External Annotation: Subtype: Link Rect: 362, 225, 397, 235 Destination: External Annotation: Subtype: Link Rect: 387, 158, 448, 170 Destination: External Annotation: Subtype: Link Rect: 453, 158, 473, 170 Destination: External Annotation: Subtype: Link Rect: 43, 29, 112, 37 Annotation: Subtype: Link Rect: 116, 29, 176, 37 Annotation: Subtype: Link Rect: 419, 29, 551, 38 Page: Label: 13 Sequence: 13 Annotations: Annotation: Subtype: Link Rect: 118, 685, 196, 697 Destination: External Annotation: Subtype: Link Rect: 201, 685, 221, 697 Destination: External Annotation: Subtype: Link Rect: 181, 651, 236, 662 Destination: External Annotation: Subtype: Link Rect: 242, 651, 262, 662 Destination: External Annotation: Subtype: Link Rect: 267, 651, 65, 651 Destination: External Annotation: Subtype: Link Rect: 69, 640, 90, 651 Destination: External Annotation: Subtype: Link Rect: 94, 640, 136, 651 Destination: External Annotation: Subtype: Link Rect: 140, 640, 160, 651 Destination: External Annotation: Subtype: Link Rect: 164, 640, 228, 651 Destination: External Annotation: Subtype: Link Rect: 232, 640, 252, 651 Destination: External Annotation: Subtype: Link Rect: 174, 571, 230, 582 Destination: External Annotation: Subtype: Link Rect: 238, 571, 258, 582 Destination: External Annotation: Subtype: Link Rect: 267, 571, 65, 571 Destination: External Annotation: Subtype: Link Rect: 70, 559, 91, 571 Destination: External Annotation: Subtype: Link Rect: 98, 559, 140, 571 Destination: External Annotation: Subtype: Link Rect: 145, 559, 165, 571 Destination: External Annotation: Subtype: Link Rect: 173, 559, 236, 571 Destination: External Annotation: Subtype: Link Rect: 241, 559, 262, 571 Destination: External Annotation: Subtype: Link Rect: 79, 296, 135, 307 Destination: External Annotation: Subtype: Link Rect: 137, 296, 158, 307 Destination: External Annotation: Subtype: Link Rect: 81, 122, 121, 132 Destination: External Annotation: Subtype: Link Rect: 43, 29, 112, 37 Annotation: Subtype: Link Rect: 116, 29, 176, 37 Annotation: Subtype: Link Rect: 419, 29, 551, 38 Page: Label: 14 Sequence: 14 Annotations: Annotation: Subtype: Link Rect: 552, 556, 303, 581 Annotation: Subtype: Link Rect: 66, 467, 200, 474 Annotation: Subtype: Link Rect: 53, 437, 153, 446 Annotation: Subtype: Link Rect: 196, 410, 285, 417 Annotation: Subtype: Link Rect: 66, 372, 200, 379 Annotation: Subtype: Link Rect: 66, 343, 164, 351 Annotation: Subtype: Link Rect: 66, 304, 154, 313 Annotation: Subtype: Link Rect: 66, 268, 155, 275 Annotation: Subtype: Link Rect: 66, 219, 154, 228 Annotation: Subtype: Link Rect: 66, 183, 144, 190 Annotation: Subtype: Link Rect: 131, 153, 221, 162 Annotation: Subtype: Link Rect: 102, 126, 188, 133 Annotation: Subtype: Link Rect: 66, 88, 197, 95 Annotation: Subtype: Link Rect: 327, 504, 457, 512 Annotation: Subtype: Link Rect: 448, 476, 517, 484 Annotation: Subtype: Link Rect: 440, 437, 528, 446 Annotation: Subtype: Link Rect: 327, 399, 385, 408 Annotation: Subtype: Link Rect: 356, 362, 442, 370 Annotation: Subtype: Link Rect: 327, 325, 461, 332 Annotation: Subtype: Link Rect: 373, 285, 453, 294 Annotation: Subtype: Link Rect: 327, 247, 435, 257 Annotation: Subtype: Link Rect: 356, 220, 486, 228 Annotation: Subtype: Link Rect: 327, 183, 457, 190 Annotation: Subtype: Link Rect: 372, 162, 501, 171 Annotation: Subtype: Link Rect: 552, 123, 313, 144 Annotation: Subtype: Link Rect: 363, 97, 448, 105 Annotation: Subtype: Link Rect: 353, 69, 442, 76 Annotation: Subtype: Link Rect: 43, 28, 112, 36 Annotation: Subtype: Link Rect: 116, 28, 176, 36 Annotation: Subtype: Link Rect: 419, 28, 551, 37 Page: Label: 15 Sequence: 15 Annotations: Annotation: Subtype: Link Rect: 292, 686, 52, 707 Annotation: Subtype: Link Rect: 95, 661, 156, 668 Annotation: Subtype: Link Rect: 66, 632, 143, 640 Annotation: Subtype: Link Rect: 66, 604, 166, 611 Annotation: Subtype: Link Rect: 132, 564, 193, 574 Annotation: Subtype: Link Rect: 66, 546, 149, 554 Annotation: Subtype: Link Rect: 147, 517, 220, 526 Annotation: Subtype: Link Rect: 66, 481, 200, 488 Annotation: Subtype: Link Rect: 152, 441, 233, 451 Annotation: Subtype: Link Rect: 154, 405, 285, 413 Annotation: Subtype: Link Rect: 66, 366, 132, 375 Annotation: Subtype: Link Rect: 66, 339, 152, 346 Annotation: Subtype: Link Rect: 66, 299, 154, 309 Annotation: Subtype: Link Rect: 363, 688, 419, 696 Annotation: Subtype: Link Rect: 356, 651, 433, 659 Annotation: Subtype: Link Rect: 363, 623, 493, 630 Annotation: Subtype: Link Rect: 442, 593, 514, 602 Annotation: Subtype: Link Rect: 440, 565, 540, 574 Annotation: Subtype: Link Rect: 327, 527, 412, 536 Annotation: Subtype: Link Rect: 552, 470, 313, 489 Annotation: Subtype: Link Rect: 552, 413, 313, 432 Annotation: Subtype: Link Rect: 492, 348, 519, 355 Annotation: Subtype: Link Rect: 519, 348, 551, 355 Annotation: Subtype: Link Rect: 304, 339, 339, 346 Annotation: Subtype: Link Rect: 339, 339, 362, 345 Annotation: Subtype: Link Rect: 362, 337, 390, 346 Annotation: Subtype: Link Rect: 43, 29, 112, 37 Annotation: Subtype: Link Rect: 116, 29, 176, 37 Annotation: Subtype: Link Rect: 419, 29, 551, 38 Checksum: 20df5336 Type: CRC32 Checksum: badc6f18ba75adebb87c959fa09368d9 Type: MD5 Checksum: 4bbb0a3f83fe921e29082e55cc2f17482d69370d Type: SHA-1 Checksum: ca5971dad3cb444d98a849f2aefca1212d1f83b8ca5a91ba70f3c4b424d6fe8f Type: SHA-256