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Haynes Creator: Elsevier Producer: Acrobat Distiller 10.0.0 (Windows) CreationDate: Fri Mar 12 10:34:11 2021 CET ModDate: Fri Mar 12 10:34:42 2021 CET Custom Metadata: yes Metadata Stream: yes Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 8 Encrypted: no Page size: 595.276 x 793.701 pts Page rot: 0 File size: 1478444 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- LKFHMK+AdvP4C9542 Type 1C WinAnsi yes yes no 382 0 LKFHLI+AdvTT5843c571 Type 1C WinAnsi yes yes no 385 0 LKFHLG+AdvP4C4E74 Type 1C Custom yes yes yes 388 0 LKFIEJ+AdvPAC3D Type 1C WinAnsi yes yes no 393 0 LKFHLH+AdvP4C4E59 Type 1C Custom yes yes yes 396 0 LKFBIL+AdvOT5fa4e291 Type 1C WinAnsi yes yes no 401 0 LKFHLF+AdvOTf2586c63 Type 1C WinAnsi yes yes no 404 0 LKFHMJ+AdvP4A5FDB Type 1C WinAnsi yes yes no 407 0 LKFHMM+AdvTTb83ee1dd.B Type 1C WinAnsi yes yes no 410 0 LKFHML+AdvOT5fa4e291+20 Type 1C WinAnsi yes yes no 413 0 LKFHLE+AdvOT5fa4e291+fb Type 1C Custom yes yes yes 416 0 LKFKDO+AdvP4C9543 Type 1C Custom yes yes yes 229 0 LKHDOG+AdvP697C Type 1C Custom yes yes no 115 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-10-02 03:27:25 CEST RepresentationInformation: pmc_33721817.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2023-03-31 12:09:11 CEST Size: 1478444 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 500 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: true NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Efficacy of linezolid on Treponema pallidum, the syphilis agent: A preclinical study Destination: Head1 Children: Item: Title: Introduction Destination: Head2 Item: Title: Methods Destination: Head3 Children: Item: Title: Compounds selection and dosage Destination: Head4 Item: Title: In vitro assessments Destination: Head5 Item: Title: Rabbit infection and treatment Destination: Head6 Item: Title: Ethics Destination: Head7 Item: Title: Clinical monitoring and sample collection Destination: Head8 Item: Title: Statistics Destination: Head9 Item: Title: Role of funders Destination: Head10 Item: Title: Results Destination: Head11 Children: Item: Title: Antimicrobial drug selection Destination: Head12 Item: Title: In-vitro effects Destination: Head13 Item: Title: Treatment effects on the animal model Destination: Head14 Item: Title: Serology and CSF involvement Destination: Head15 Item: Title: Discussion Destination: Head16 Item: Title: Contributors Destination: Head17 Children: Item: Title: Acknowledgements Destination: Head18 Item: Title: Data sharing statement Destination: Head19 Item: Title: Declaration of Competing Interests Destination: Head20 Item: Title: Supplementary materials Destination: Head21 Children: Item: Title: References Destination: Head22 Info: Title: Efficacy of linezolid on Treponema pallidum, the syphilis agent: A preclinical study Author: Austin M. 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EBioMedicine, 65 (2021) 103281. doi:10.1016/j.ebiom.2021.103281 Treponema pallidum Syphilis Yaws Repurposing Linezolid Preclinical Efficacy of linezolid on Treponema pallidum, the syphilis agent: A preclinical study Austin M. Haynes Lorenzo Giacani Marti Vall Mayans Maria Ubals Carles Nieto Clara Pérez-Mañá Llorenç Quintó Emily Romeis Oriol Mitjà uuid:fd8cfc10-4791-4a8b-8025-00abb91efa0c uuid:932a894b-13e7-44e4-b6a9-13f81c8e096d journal © 2021 The Authors. Published by Elsevier B.V. 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