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Conclusions Item: Title: Trial registration Item: Title: 1 Introduction Item: Title: 2 Materials and Methods Children: Item: Title: 2.1 Study Drug and Treatment Item: Title: 2.2 Study Design Item: Title: 2.3 Study Population and Assessments Item: Title: 2.4 Analytical Methods Children: Item: Title: 2.4.1 Pharmacokinetics Item: Title: 2.4.2 Plasma Unbound Concentrations Item: Title: 2.4.3 KDM1A Target Engagement Item: Title: 3 Results Children: Item: Title: 3.1 Safety and Tolerability Item: Title: 3.2 Pharmacokinetics Item: Title: 3.3 Pharmacodynamics Item: Title: 3.4 Neuropsychological Assessments Item: Title: 4 Discussion Item: Title: 5 Conclusion Item: Title: Acknowledgements Item: Title: References Info: Title: First-in-Human Randomized Trial to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of the KDM1A Inhibitor Vafidemstat Author: Rosa María Antonijoan Subject: CNS Drugs, https://doi.org/10.1007/s40263-021-00797-x Creator: Springer CreationDate: Tue Mar 23 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