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Reyes-López and Enric Gisbert Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Mon Mar 8 08:53:05 2021 CET ModDate: Mon Mar 8 09:33:45 2021 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 19 Encrypted: no Page size: 595.26 x 779.52 pts Page rot: 0 File size: 7266138 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- ZBPNIZ+HelveticaNeueLTStd-Bd Type 1C Custom yes yes no 36 0 ZUAWSS+HelveticaNeueLTStd-Lt Type 1C Custom yes yes no 41 0 VANPNG+HelveticaNeueLTStd-BdIt Type 1C WinAnsi yes yes no 54 0 OVXSGQ+HelveticaNeueLTStd-LtIt Type 1C Custom yes yes no 56 0 VRVKKF+HelveticaNeueLTStd-MdIt Type 1C WinAnsi yes yes no 62 0 ARNWRS+MTSY Type 1C Custom yes yes yes 93 0 RJENPK+MinionPro-Bold Type 1C Custom yes yes no 96 0 UOAYUW+MTGU Type 1C Custom yes yes no 99 0 QMQJXH+RMTMI Type 1C Custom yes yes no 101 0 NHQYVE+MinionPro-Regular Type 1C Custom yes yes no 70 0 QRSMUL+MinionPro-It Type 1C Custom yes yes no 79 0 MBYTOP+HelveticaNeueLTStd-Md Type 1C WinAnsi yes yes no 112 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-05-27 02:47:44 CEST RepresentationInformation: pmc_33777020.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-03-31 12:09:17 CEST Size: 7266138 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 578 FreeObjects: 24 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: Carvacrol, Thymol, and Garlic Essential Oil Promote Skin Innate Immunity in Gilthead Seabream (Sparus aurata) Through the Mul琀椀昀愀挀琀漀爀椀愀氀 䴀漀搀甀氀愀琀椀漀渀 漀昀 琀栀攀 匀攀挀爀攀琀漀爀礀 倀愀琀栀眀愀礀 愀渀搀 䔀渀栀愀渀挀攀洀攀渀琀 漀昀 䴀甀挀甀猀 倀爀漀琀攀挀琀椀瘀攀 䌀愀瀀愀挀椀琀礩㸾൥湤潢樍㘠〠潢樍㰼⽐慲敮琠㔠〠刯乥硴‷‰⁒⽄敳琯獥捴楯渪⸲⽁捴楯港䝯呯⽔楴汥⣾＀䤀渀琀爀漀搀甀挀琀椀漀温㸾൥湤潢樍㈸‰扪഼㰯偡牥湴‵‰⁒⽄敳琯獥捴楯渪⸲㐯䅣瑩潮⽇潔漯偲敶′㜠〠刯呩瑬攨References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4d3167f4 Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@ed9d034 Item: Title: Materials and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6121c9d6 Children: Item: Title: Diets and Fish Rearing Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@87f383f Item: Title: Sampling Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Item: Title: Skin Transcriptomic Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Children: Item: Title: RNA Isolation and Quality Control Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: Microarray Hybridization and Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: Skin Mucus Parameters Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Children: Item: Title: Bacterial Growth Assessment in Skin Mucus Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: Skin Mucus Metabolites and Cortisol Analyses Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: Statistical Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Children: Item: Title: Skin Transcriptomic Profile Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: Bacterial Growth Capacity on Skin Mucus Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: Mucus Stress Biomarkers Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: Data Availability Statement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: Ethics Statement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: Author Contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: Funding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: Acknowledgments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: Supplementary Material Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: References Destination: 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Reyes-López and Enric Gisbert Subject: One of the main targets for the use of phytogenics in aquafeeds is the mucosal tissues as they constitute a physical and biochemical shield against environmental and pathogenic threats, comprising elements from both the innate and acquired immunity. 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phytogenics in aquafeeds is the mucosal tissues as they constitute a physical and biochemical shield against environmental and pathogenic threats, comprising elements from both the innate and acquired immunity. Felipe E. 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78 Destination: External Annotation: Subtype: Link Rect: 150, 67, 161, 78 Destination: External Annotation: Subtype: Link Rect: 307, 708, 318, 720 Destination: External Annotation: Subtype: Link Rect: 404, 674, 416, 685 Destination: External Annotation: Subtype: Link Rect: 376, 662, 387, 674 Destination: External Annotation: Subtype: Link Rect: 428, 525, 439, 536 Destination: External Annotation: Subtype: Link Rect: 486, 353, 497, 365 Destination: External Annotation: Subtype: Link Rect: 449, 135, 460, 147 Destination: External Annotation: Subtype: Link Rect: 463, 135, 474, 147 Destination: External Annotation: Subtype: Link Rect: 347, 124, 359, 135 Destination: External Annotation: Subtype: Link Rect: 352, 78, 363, 90 Destination: External Annotation: Subtype: Link Rect: 43, 29, 117, 37 Annotation: Subtype: Link Rect: 120, 29, 180, 37 Annotation: Subtype: Link Rect: 426, 29, 551, 38 Page: Label: 14 Sequence: 14 Annotations: Annotation: Subtype: Link Rect: 110, 697, 122, 708 Destination: External Annotation: Subtype: Link Rect: 274, 651, 285, 662 Destination: External Annotation: Subtype: Link Rect: 236, 502, 247, 514 Destination: External Annotation: Subtype: Link Rect: 175, 456, 186, 468 Destination: External Annotation: Subtype: Link Rect: 89, 399, 101, 410 Destination: External Annotation: Subtype: Link Rect: 149, 307, 165, 319 Destination: External Annotation: Subtype: Link Rect: 276, 307, 287, 319 Destination: External Annotation: Subtype: Link Rect: 72, 67, 83, 78 Destination: External Annotation: Subtype: Link Rect: 530, 708, 546, 720 Destination: External Annotation: Subtype: Link Rect: 477, 674, 493, 685 Destination: External Annotation: Subtype: Link Rect: 517, 640, 528, 651 Destination: External Annotation: Subtype: Link Rect: 530, 525, 546, 536 Destination: External Annotation: Subtype: Link Rect: 307, 491, 323, 502 Destination: External Annotation: Subtype: Link Rect: 477, 456, 492, 468 Destination: External Annotation: Subtype: Link Rect: 441, 422, 456, 433 Destination: External Annotation: Subtype: Link Rect: 331, 399, 346, 410 Destination: External Annotation: Subtype: Link Rect: 373, 353, 388, 365 Destination: External Annotation: Subtype: Link Rect: 363, 319, 378, 330 Destination: External Annotation: Subtype: Link Rect: 381, 319, 397, 330 Destination: External Annotation: Subtype: Link Rect: 530, 319, 546, 330 Destination: External Annotation: Subtype: Link Rect: 339, 227, 354, 239 Destination: External Annotation: Subtype: Link Rect: 381, 216, 392, 227 Destination: External Annotation: Subtype: Link Rect: 398, 216, 409, 227 Destination: External Annotation: Subtype: Link Rect: 416, 216, 431, 227 Destination: External Annotation: Subtype: Link Rect: 438, 216, 454, 227 Destination: External Annotation: Subtype: Link Rect: 383, 193, 398, 204 Destination: External Annotation: Subtype: Link Rect: 534, 193, 546, 204 Destination: External Annotation: Subtype: Link Rect: 363, 135, 379, 147 Destination: External Annotation: Subtype: Link Rect: 43, 29, 117, 37 Annotation: Subtype: Link Rect: 120, 29, 180, 37 Annotation: Subtype: Link Rect: 426, 29, 551, 38 Page: Label: 15 Sequence: 15 Annotations: Annotation: Subtype: Link Rect: 105, 697, 121, 708 Destination: External Annotation: Subtype: Link Rect: 155, 685, 171, 697 Destination: External Annotation: Subtype: Link Rect: 143, 674, 158, 685 Destination: External Annotation: Subtype: Link Rect: 274, 651, 285, 662 Destination: External Annotation: Subtype: Link Rect: 126, 617, 142, 628 Destination: External Annotation: Subtype: Link Rect: 117, 594, 133, 605 Destination: External Annotation: Subtype: Link Rect: 89, 525, 105, 536 Destination: External Annotation: Subtype: Link Rect: 108, 525, 123, 536 Destination: External Annotation: Subtype: Link Rect: 121, 468, 137, 479 Destination: External Annotation: Subtype: Link Rect: 141, 468, 156, 479 Destination: External Annotation: Subtype: Link Rect: 257, 468, 268, 479 Destination: External Annotation: Subtype: Link Rect: 272, 468, 287, 479 Destination: External Annotation: Subtype: Link Rect: 105, 422, 120, 433 Destination: External Annotation: Subtype: Link Rect: 123, 422, 139, 433 Destination: External Annotation: Subtype: Link Rect: 155, 342, 166, 353 Destination: External Annotation: Subtype: Link Rect: 168, 342, 184, 353 Destination: External Annotation: Subtype: Link Rect: 77, 204, 92, 216 Destination: External Annotation: Subtype: Link Rect: 330, 451, 429, 462 Destination: External Annotation: Subtype: Link Rect: 43, 29, 117, 37 Annotation: Subtype: Link Rect: 120, 29, 180, 37 Annotation: Subtype: Link Rect: 426, 29, 551, 38 Page: Label: 16 Sequence: 16 Annotations: Annotation: Subtype: Link Rect: 552, 600, 303, 625 Annotation: Subtype: Link Rect: 194, 527, 263, 534 Annotation: Subtype: Link Rect: 74, 489, 189, 496 Annotation: Subtype: Link Rect: 129, 459, 186, 468 Annotation: Subtype: Link Rect: 189, 430, 269, 440 Annotation: Subtype: Link Rect: 99, 394, 215, 402 Annotation: Subtype: Link Rect: 96, 366, 195, 373 Annotation: Subtype: Link Rect: 97, 319, 183, 326 Annotation: Subtype: Link Rect: 165, 289, 223, 297 Annotation: Subtype: Link Rect: 175, 262, 290, 269 Annotation: Subtype: Link Rect: 74, 232, 163, 241 Annotation: Subtype: Link Rect: 74, 205, 143, 213 Annotation: Subtype: Link Rect: 210, 186, 279, 194 Annotation: Subtype: Link Rect: 85, 165, 160, 175 Annotation: Subtype: Link Rect: 202, 137, 282, 146 Annotation: Subtype: Link Rect: 143, 110, 258, 118 Annotation: Subtype: Link Rect: 142, 80, 276, 90 Annotation: Subtype: Link Rect: 447, 536, 535, 544 Annotation: Subtype: Link Rect: 422, 497, 492, 506 Annotation: Subtype: Link Rect: 334, 449, 430, 458 Annotation: Subtype: Link Rect: 453, 412, 519, 421 Annotation: Subtype: Link Rect: 334, 374, 380, 383 Annotation: Subtype: Link Rect: 334, 337, 430, 345 Annotation: Subtype: Link Rect: 368, 307, 444, 317 Annotation: Subtype: Link Rect: 334, 270, 418, 279 Annotation: Subtype: Link Rect: 444, 241, 523, 251 Annotation: Subtype: Link Rect: 552, 202, 320, 223 Annotation: Subtype: Link Rect: 368, 158, 455, 165 Annotation: Subtype: Link Rect: 421, 139, 487, 146 Annotation: Subtype: Link Rect: 426, 109, 488, 118 Annotation: Subtype: Link Rect: 490, 80, 545, 90 Annotation: Subtype: Link Rect: 43, 28, 117, 36 Annotation: Subtype: Link Rect: 120, 28, 180, 36 Annotation: Subtype: Link Rect: 426, 28, 551, 37 Page: Label: 17 Sequence: 17 Annotations: Annotation: Subtype: Link Rect: 133, 688, 210, 696 Annotation: Subtype: Link Rect: 74, 650, 157, 659 Annotation: Subtype: Link Rect: 143, 623, 228, 630 Annotation: Subtype: Link Rect: 90, 583, 170, 593 Annotation: Subtype: Link Rect: 74, 547, 153, 554 Annotation: Subtype: Link Rect: 74, 500, 158, 508 Annotation: Subtype: Link Rect: 160, 470, 264, 479 Annotation: Subtype: Link Rect: 74, 434, 197, 441 Annotation: Subtype: Link Rect: 104, 394, 197, 403 Annotation: Subtype: Link Rect: 74, 367, 145, 375 Annotation: Subtype: Link Rect: 137, 338, 204, 346 Annotation: Subtype: Link Rect: 140, 299, 225, 308 Annotation: Subtype: Link Rect: 195, 281, 273, 290 Annotation: Subtype: Link Rect: 160, 254, 226, 261 Annotation: Subtype: Link Rect: 74, 214, 129, 224 Annotation: Subtype: Link Rect: 111, 176, 207, 186 Annotation: Subtype: Link Rect: 154, 150, 239, 157 Annotation: Subtype: Link Rect: 74, 102, 159, 110 Annotation: Subtype: Link Rect: 74, 72, 169, 82 Annotation: Subtype: Link Rect: 334, 678, 414, 687 Annotation: Subtype: Link Rect: 361, 640, 437, 649 Annotation: Subtype: Link Rect: 334, 613, 415, 621 Annotation: Subtype: Link Rect: 341, 574, 417, 583 Annotation: Subtype: Link Rect: 334, 536, 410, 545 Annotation: Subtype: Link Rect: 334, 479, 410, 489 Annotation: Subtype: Link Rect: 552, 423, 320, 442 Annotation: Subtype: Link Rect: 334, 396, 400, 403 Annotation: Subtype: Link Rect: 334, 366, 417, 375 Annotation: Subtype: Link Rect: 386, 348, 471, 356 Annotation: Subtype: Link Rect: 334, 309, 429, 318 Annotation: Subtype: Link Rect: 393, 273, 478, 280 Annotation: Subtype: Link Rect: 334, 224, 412, 233 Annotation: Subtype: Link Rect: 393, 195, 478, 204 Annotation: Subtype: Link Rect: 451, 167, 525, 176 Annotation: Subtype: Link Rect: 375, 131, 486, 138 Annotation: Subtype: Link Rect: 410, 112, 493, 119 Annotation: Subtype: Link Rect: 552, 73, 320, 92 Annotation: Subtype: Link Rect: 43, 29, 117, 37 Annotation: Subtype: Link Rect: 120, 29, 180, 37 Annotation: Subtype: Link Rect: 426, 29, 551, 38 Page: Label: 18 Sequence: 18 Annotations: Annotation: Subtype: Link Rect: 74, 678, 152, 687 Annotation: Subtype: Link Rect: 292, 639, 60, 660 Annotation: Subtype: Link Rect: 181, 574, 250, 583 Annotation: Subtype: Link Rect: 74, 527, 150, 536 Annotation: Subtype: Link Rect: 74, 489, 150, 498 Annotation: Subtype: Link Rect: 117, 441, 199, 451 Annotation: Subtype: Link Rect: 114, 394, 206, 403 Annotation: Subtype: Link Rect: 153, 367, 214, 375 Annotation: Subtype: Link Rect: 74, 329, 158, 337 Annotation: Subtype: Link Rect: 74, 309, 149, 318 Annotation: Subtype: Link Rect: 194, 281, 266, 289 Annotation: Subtype: Link Rect: 112, 254, 181, 261 Annotation: Subtype: Link Rect: 133, 224, 232, 233 Annotation: Subtype: Link Rect: 200, 197, 265, 204 Annotation: Subtype: Link Rect: 207, 167, 269, 176 Annotation: Subtype: Link Rect: 74, 140, 134, 148 Annotation: Subtype: Link Rect: 292, 90, 60, 111 Annotation: Subtype: Link Rect: 368, 697, 444, 706 Annotation: Subtype: Link Rect: 417, 659, 493, 668 Annotation: Subtype: Link Rect: 485, 631, 542, 640 Annotation: Subtype: Link Rect: 368, 583, 444, 593 Annotation: Subtype: Link Rect: 334, 557, 389, 564 Annotation: Subtype: Link Rect: 359, 528, 452, 536 Annotation: Subtype: Link Rect: 334, 499, 430, 507 Annotation: Subtype: Link Rect: 352, 434, 413, 441 Annotation: Subtype: Link Rect: 334, 396, 419, 403 Annotation: Subtype: Link Rect: 448, 356, 524, 366 Annotation: Subtype: Link Rect: 433, 318, 539, 328 Annotation: Subtype: Link Rect: 438, 281, 514, 290 Annotation: Subtype: Link Rect: 334, 252, 439, 261 Annotation: Subtype: Link Rect: 421, 214, 496, 224 Annotation: Subtype: Link Rect: 368, 187, 432, 195 Annotation: Subtype: Link Rect: 334, 159, 418, 167 Annotation: Subtype: Link Rect: 334, 129, 440, 138 Annotation: Subtype: Link Rect: 372, 91, 478, 101 Annotation: Subtype: Link Rect: 43, 29, 117, 37 Annotation: Subtype: Link Rect: 120, 29, 180, 37 Annotation: Subtype: Link Rect: 426, 29, 551, 38 Page: Label: 19 Sequence: 19 Annotations: Annotation: Subtype: Link Rect: 74, 689, 159, 696 Annotation: Subtype: Link Rect: 85, 640, 160, 649 Annotation: Subtype: Link Rect: 170, 602, 274, 612 Annotation: Subtype: Link Rect: 177, 564, 281, 574 Annotation: Subtype: Link Rect: 99, 536, 175, 545 Annotation: Subtype: Link Rect: 74, 508, 160, 517 Annotation: Subtype: Link Rect: 133, 470, 239, 479 Annotation: Subtype: Link Rect: 196, 441, 270, 450 Annotation: Subtype: Link Rect: 74, 413, 178, 422 Annotation: Subtype: Link Rect: 292, 374, 60, 395 Annotation: Subtype: Link Rect: 292, 317, 60, 338 Annotation: Subtype: Link Rect: 390, 697, 465, 706 Annotation: Subtype: Link Rect: 393, 669, 473, 678 Annotation: Subtype: Link Rect: 386, 642, 471, 649 Annotation: Subtype: Link Rect: 334, 602, 410, 612 Annotation: Subtype: Link Rect: 354, 555, 433, 564 Annotation: Subtype: Link Rect: 390, 519, 475, 526 Annotation: Subtype: Link Rect: 377, 470, 481, 479 Annotation: Subtype: Link Rect: 334, 441, 403, 450 Annotation: Subtype: Link Rect: 380, 339, 407, 345 Annotation: Subtype: Link Rect: 409, 339, 441, 345 Annotation: Subtype: Link Rect: 442, 339, 478, 346 Annotation: Subtype: Link Rect: 480, 339, 503, 345 Annotation: Subtype: Link Rect: 505, 337, 534, 346 Annotation: Subtype: Link Rect: 43, 29, 117, 37 Annotation: Subtype: Link Rect: 120, 29, 180, 37 Annotation: Subtype: Link Rect: 426, 29, 551, 38 Checksum: 57175840 Type: CRC32 Checksum: a3dde2fac7bc4b62bb6c8f7ba4621247 Type: MD5 Checksum: c79f48f80a4072e77052f8606632111248317d5e Type: SHA-1