f96dcb91597a73d55609295e9287173e pmc_33794896.pdf a39cbef062509afee7429427e2c9a077d0dcce82 pmc_33794896.pdf 9a30c7ee847dc9d0981dd447e62a7a0918ef2424e787b9451844b70803968e67 pmc_33794896.pdf Title: Oxytocin in bovine saliva: validation of two assays and changes in parturition and at weaning Subject: BMC Veterinary Research, 2021, doi:10.1186/s12917-021-02838-5 Keywords: Calves,Cow,Oxytocin,Saliva Author: Marina López-Arjona Creator: Arbortext Advanced Print Publisher 9.1.440/W Unicode Producer: Acrobat Distiller 10.0.0 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Tue Mar 30 05:09:21 2021 CEST ModDate: Thu Apr 1 13:34:06 2021 CEST Custom Metadata: no Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 8 Encrypted: no Page size: 595.276 x 790.866 pts Page rot: 0 File size: 788413 bytes Optimized: no PDF version: 1.3 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- BIJBFI+AdvTT7329fd89.I Type 1C WinAnsi yes yes no 3 0 MyriadPro-Regular Type 1C Custom yes no yes 14 0 BIIPGO+AdvTTaf7f9f4f.B Type 1C WinAnsi yes yes no 16 0 BIJAJI+AdvTTe45e47d2 Type 1C WinAnsi yes yes no 17 0 BIJAKI+AdvTTb5929f4c Type 1C WinAnsi yes yes no 18 0 BIJAKJ+AdvTT99c4c969 Type 1C WinAnsi yes yes no 19 0 BIJAKK+AdvTT86d47313 Type 1C WinAnsi yes yes no 20 0 BIJBBJ+AdvTTb5929f4c+20 Type 1C WinAnsi yes yes no 43 0 BIJBKJ+AdvTT8861b38f.I Type 1C WinAnsi yes yes no 13 0 BIJBJJ+AdvTT86d47313+20 Type 1C WinAnsi yes yes no 15 0 RCWNTN+Helvetica-Bold Type 1C WinAnsi yes yes no 104 0 BIJDCC+AdvTT1b53b5fb.I Type 1C WinAnsi yes yes no 100 0 BIJFHF+AdvTT86d47313+22 Type 1C Custom yes yes no 170 0 BIJFKH+AdvTTaf7f9f4f.B+20 Type 1C WinAnsi yes yes no 175 0 BIJFIG+AdvTT99c4c969+20 Type 1C WinAnsi yes yes no 189 0 BIJFKG+AdvTTb5929f4c+03 Type 1C Custom yes yes yes 182 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-10-02 03:25:59 CEST RepresentationInformation: pmc_33794896.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2023-03-31 12:09:20 CEST Size: 788413 Format: PDF Version: 1.3 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 358 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Abstract Destination: sectionAbs1 Children: Item: Title: Background Destination: sectionASec1 Item: Title: Results Destination: sectionASec2 Item: Title: Conclusions Destination: sectionASec3 Item: Title: Background Destination: sectionSec1 Item: Title: Results Destination: sectionSec2 Children: Item: Title: Optimization of monoclonal and polyclonal assay protocol for oxytocin measurement in bovine saliva Destination: sectionSec3 Item: Title: Monoclonal and polyclonal assay validation Destination: sectionSec4 Item: Title: Evaluation of the R/A effect Destination: sectionSec5 Item: Title: Oxytocin concentrations in saliva of cows around parturition Destination: sectionSec6 Item: Title: Oxytocin concentrations in saliva of calves after weaning and grouping Destination: sectionSec7 Item: Title: Discussion Destination: sectionSec8 Item: Title: Conclusions Destination: sectionSec9 Item: Title: Methods Destination: sectionSec10 Children: Item: Title: Optimization of monoclonal and polyclonal assay protocol for oxytocin measurement in cow saliva Destination: sectionSec11 Item: Title: Monoclonal and polyclonal assay validation Destination: sectionSec12 Item: Title: Evaluation of R/A procedure Destination: sectionSec13 Item: Title: Study of oxytocin changes around parturition Destination: sectionSec14 Item: Title: Study of oxytocin changes at weaning and grouping Destination: sectionSec15 Item: Title: Statistical analysis Destination: sectionSec16 Item: Title: Acknowledgements Destination: section1 Item: Title: Authors’ contributions Destination: section2 Item: Title: Funding Destination: section3 Item: Title: Availability of data and materials Destination: section4 Item: Title: Declarations Destination: section5 Item: Title: Ethics approval and consent to participate Destination: sectionFPar1 Item: Title: Consent for publication Destination: sectionFPar2 Item: Title: Competing interests Destination: sectionFPar3 Item: Title: Author details Destination: section6 Item: Title: References Destination: sectionBib1 Item: Title: Publisher’s Note Destination: ArtNote1 Info: Title: Oxytocin in bovine saliva: validation of two assays and changes in parturition and at weaning Author: Marina López-Arjona Subject: BMC Veterinary Research, 2021, doi:10.1186/s12917-021-02838-5 Keywords: Calves,Cow,Oxytocin,Saliva Creator: Arbortext Advanced Print Publisher 9.1.440/W Unicode Producer: Acrobat Distiller 10.0.0 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Tue Mar 30 05:09:21 CEST 2021 ModDate: Thu Apr 01 13:34:06 CEST 2021 ID: 0x61141a54de275b0395ccf6ed2192ddab, 0x291c8bc0599da7dbf4765fcecd9155a5 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 176 ImageHeight: 182 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 688 ImageHeight: 126 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 33 ImageHeight: 63 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 738 ImageHeight: 431 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1362 ImageHeight: 928 BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1132 ImageHeight: 791 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1100 ImageHeight: 90 ColorSpace: black is zero BitsPerSample: 1 BitsPerSampleUnit: integer Filter: FlateDecode Fonts: Type1: Font: BaseFont: BIJBFI+AdvTT7329fd89.I FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: BIJBFI+AdvTT7329fd89.I Flags: Nonsymbolic FontBBox: -104, -250, 885, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: BIJDCC+AdvTT1b53b5fb.I FontSubset: true FirstChar: 32 LastChar: 80 FontDescriptor: FontName: BIJDCC+AdvTT1b53b5fb.I Flags: Nonsymbolic FontBBox: -114, -250, 864, 854 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: RCWNTN+Helvetica-Bold FontSubset: true FirstChar: 0 LastChar: 255 FontDescriptor: FontName: RCWNTN+Helvetica-Bold Flags: Nonsymbolic, ForceBold FontBBox: -170, -228, 1003, 962 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: BIJFHF+AdvTT86d47313+22 FontSubset: true FirstChar: 21 LastChar: 22 FontDescriptor: FontName: BIJFHF+AdvTT86d47313+22 Flags: Nonsymbolic FontBBox: -166, -250, 1031, 864 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: BIJBBJ+AdvTTb5929f4c+20 FontSubset: true FirstChar: 32 LastChar: 150 FontDescriptor: FontName: BIJBBJ+AdvTTb5929f4c+20 Flags: Nonsymbolic FontBBox: -447, -208, 1375, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: BIJBKJ+AdvTT8861b38f.I FontSubset: true FirstChar: 32 LastChar: 114 FontDescriptor: FontName: BIJBKJ+AdvTT8861b38f.I Flags: Nonsymbolic FontBBox: -187, -239, 1062, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MyriadPro-Regular FirstChar: 1 LastChar: 255 FontDescriptor: FontName: MyriadPro-Regular Flags: Nonsymbolic FontBBox: -157, -250, 1126, 952 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: BIJBJJ+AdvTT86d47313+20 FontSubset: true FirstChar: 32 LastChar: 150 FontDescriptor: FontName: BIJBJJ+AdvTT86d47313+20 Flags: Nonsymbolic FontBBox: -354, -218, 1291, 812 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: BIJFKH+AdvTTaf7f9f4f.B+20 FontSubset: true FirstChar: 32 LastChar: 146 FontDescriptor: FontName: BIJFKH+AdvTTaf7f9f4f.B+20 Flags: Nonsymbolic FontBBox: -468, -197, 1656, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: BIIPGO+AdvTTaf7f9f4f.B FontSubset: true FirstChar: 32 LastChar: 117 FontDescriptor: FontName: BIIPGO+AdvTTaf7f9f4f.B Flags: Nonsymbolic FontBBox: -31, -250, 875, 895 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: BIJAJI+AdvTTe45e47d2 FontSubset: true FirstChar: 32 LastChar: 243 FontDescriptor: FontName: BIJAJI+AdvTTe45e47d2 Flags: Nonsymbolic FontBBox: -41, -250, 833, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: BIJAKI+AdvTTb5929f4c FontSubset: true FirstChar: 32 LastChar: 252 FontDescriptor: FontName: BIJAKI+AdvTTb5929f4c Flags: Nonsymbolic FontBBox: -41, -250, 812, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: BIJAKJ+AdvTT99c4c969 FontSubset: true FirstChar: 32 LastChar: 122 FontDescriptor: FontName: BIJAKJ+AdvTT99c4c969 Flags: Nonsymbolic FontBBox: -41, -250, 854, 885 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: BIJAKK+AdvTT86d47313 FontSubset: true FirstChar: 32 LastChar: 252 FontDescriptor: FontName: BIJAKK+AdvTT86d47313 Flags: Serif, Nonsymbolic FontBBox: -20, -239, 1020, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: BIJFKG+AdvTTb5929f4c+03 FontSubset: true FirstChar: 1 LastChar: 4 FontDescriptor: FontName: BIJFKG+AdvTTb5929f4c+03 Flags: Symbolic FontBBox: -531, -260, 802, 968 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: BIJFIG+AdvTT99c4c969+20 FontSubset: true FirstChar: 32 LastChar: 146 FontDescriptor: FontName: BIJFIG+AdvTT99c4c969+20 Flags: Nonsymbolic FontBBox: -447, -197, 1583, 864 FontFile3: true Encoding: WinAnsiEncoding XMP: Calves,Cow,Oxytocin,Saliva Acrobat Distiller 10.0.0 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) application/pdf 10.1186/s12917-021-02838-5 BMC Veterinary Research BMC Veterinary Research, 2021, doi:10.1186/s12917-021-02838-5 Calves Cow Oxytocin Saliva Oxytocin in bovine saliva: validation of two assays and changes in parturition and at weaning Marina López-Arjona Eva Mainau Elena Navarro María Dolores Contreras-Aguilar Damián Escribano Sandra V. Mateo Xavier Manteca José Joaquín Cerón Silvia Martínez-Subiela 2021-04-01T13:34:06+02:00 2021-04-01T13:34:06+02:00 2021-03-30T11:09:21+08:00 Arbortext Advanced Print Publisher 9.1.440/W Unicode uuid:9aa95400-8e83-4e9d-8349-3c3dc5b5e677 uuid:84001b62-d463-4b11-939d-1d3fe1e4ccc4 default 1 converted uuid:9aa95400-8e83-4e9d-8349-3c3dc5b5e677 converted to PDF/A-2b pdfToolbox 2021-03-30T11:20:13+08:00 2 B Springer Nature ORCID Schema http://springernature.com/ns/xmpExtensions/2.0/ sn authorInfo Bag AuthorInformation external Author information: contains the name of each author and his/her ORCID (ORCiD: Open Researcher and Contributor ID). An ORCID is a persistent identifier (a non-proprietary alphanumeric code) to uniquely identify scientific and other academic authors. editorInfo Bag EditorInformation external Editor information: contains the name of each editor and his/her ORCID identifier. seriesEditorInfo Bag SeriesEditorInformation external Series editor information: contains the name of each series editor and his/her ORCID identifier. AuthorInformation http://springernature.com/ns/xmpExtensions/2.0/authorInfo/ author Specifies the types of author information: name and ORCID of an author. name Text Gives the name of an author. orcid URI Gives the ORCID of an author. EditorInformation http://springernature.com/ns/xmpExtensions/2.0/editorInfo/ editor Specifies the types of editor information: name and ORCID of an editor. name Text Gives the name of an editor. orcid URI Gives the ORCID of an editor. SeriesEditorInformation http://springernature.com/ns/xmpExtensions/2.0/seriesEditorInfo/ seriesEditor Specifies the types of series editor information: name and ORCID of a series editor. name Text Gives the name of a series editor. orcid URI Gives the ORCID of a series editor. http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. OriginalDocumentID URI internal A reference to the original document from which this one is derived. It is a minimal reference; missing components can be assumed to be unchanged. For example, a new version might only need to specify the instance ID and version number of the previous version, or a rendition might only need to specify the instance ID and rendition class of the original. DerivedFrom ResourceRef Identifies a portion of a document. This can be a position at which the document has been changed since the most recent event history (stEvt:changed). For a resource within an xmpMM:Ingredients list, the ResourceRef uses this type to identify both the portion of the containing document that refers to the resource, and the portion of the referenced resource that is referenced. http://ns.adobe.com/xap/1.0/sType/Part# stPart Part http://ns.adobe.com/xap/1.0/t/pg/ xmpTPg XMP Paged-Text internal A structure containing the characteristics of a font used in a document Fonts Bag Font internal XMP08 Spec: An ordered array of plate names that are needed to print the document (including any in contained documents). PlateNames Seq Text A structure containing the characteristics of a font used in a document. http://ns.adobe.com/xap/1.0/sType/Font# stFnt Font http://ns.adobe.com/pdfx/1.3/ pdfx Adobe Document Info PDF eXtension Schema internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 496, 635, 538, 677 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 178, 268, 183, 278 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 118, 244, 123, 254 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 114, 232, 119, 242 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 127, 232, 132, 242 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 59, 220, 64, 230 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 130, 220, 135, 230 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 141, 220, 146, 230 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 369, 256, 373, 266 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 454, 184, 458, 194 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 400, 73, 518, 80 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 338, 65, 477, 72 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 114, 183, 157, 190 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 261, 693, 266, 702 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 275, 693, 285, 702 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 196, 681, 206, 690 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 157, 657, 167, 666 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 103, 561, 112, 570 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 118, 561, 127, 570 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 178, 549, 188, 558 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 139, 537, 149, 546 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 100, 525, 110, 534 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 168, 513, 178, 522 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 220, 429, 230, 438 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 251, 171, 256, 180 Flags: Print AppearanceDictionary: true Destination: 8 Annotation: Subtype: Link Rect: 277, 171, 281, 180 Flags: Print AppearanceDictionary: true Destination: 105 Annotation: Subtype: Link Rect: 430, 189, 435, 198 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 458, 129, 463, 138 Flags: Print AppearanceDictionary: true Destination: 134 Thumb: true Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 326, 225, 331, 234 Flags: Print AppearanceDictionary: true Destination: 174 Thumb: true Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 85, 393, 89, 402 Flags: Print AppearanceDictionary: true Destination: 174 Annotation: Subtype: Link Rect: 227, 345, 236, 354 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 241, 345, 251, 354 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 211, 273, 221, 282 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 59, 225, 64, 234 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 307, 405, 312, 414 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 345, 357, 350, 366 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 508, 297, 513, 306 Flags: Print AppearanceDictionary: true Destination: 51 Thumb: true Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 173, 369, 183, 378 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 504, 381, 514, 390 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 523, 381, 533, 390 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 330, 357, 340, 366 Flags: Print AppearanceDictionary: true Destination: 51 Thumb: true Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 162, 633, 171, 642 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 165, 585, 175, 594 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 181, 585, 191, 594 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 59, 513, 69, 522 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 75, 513, 85, 522 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 159, 429, 168, 438 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 174, 429, 184, 438 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 153, 153, 163, 162 Flags: Print AppearanceDictionary: true Destination: 51 Thumb: true Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 134, 573, 143, 582 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 205, 81, 214, 90 Flags: Print AppearanceDictionary: true Destination: 51 Annotation: Subtype: Link Rect: 389, 357, 399, 366 Flags: Print AppearanceDictionary: true Destination: 51 Thumb: true Page: Sequence: 8 Thumb: true Checksum: 3c1634cc Type: CRC32 Checksum: f96dcb91597a73d55609295e9287173e Type: MD5 Checksum: a39cbef062509afee7429427e2c9a077d0dcce82 Type: SHA-1 Checksum: 9a30c7ee847dc9d0981dd447e62a7a0918ef2424e787b9451844b70803968e67 Type: SHA-256