e4cce58176c61520319c87a4323d266f pmc_33801650.pdf 3f6ecf958fccb0dd0ef53b8108fa356c5068f69d pmc_33801650.pdf 8f17220d7a4bc7eea94481f03035283a7d219147138cd9ea8a93f19a2dc4c531 pmc_33801650.pdf Title: Blood Donations and Transfusions during the COVID-19 Pandemic in Spain: Impact According to Autonomous Communities and Hospitals Subject: Worldwide, the COVID-19 pandemic has caused a decline in blood donations, between 30% and 70% in some of the most affected countries. In Spain, during the initial eight weeks after the State of Emergency was decreed on 14 March 2020, in the weekly reports of the Health Ministry, an average decrease of 20% was observed between 11 and week 25 compared with the 2018 donation. We aimed to investigate the impact of the COVID-19 pandemic on blood donations and blood distribution in four autonomous communities, and to explore the evolution of the consumption of blood components (BCs) in ten hospitals of six autonomous communities. We performed a prospective study of grouped cohorts on the donation and distribution of blood in four regional transfusion centers in four autonomous communities in Spain, and a retrospective study of the consumption of blood components in ten hospitals in six autonomous communities. Regarding donations, there was no significant decrease in donations, with differences between autonomous communities, which started between 1 and 15 March 2020 (-11%). The increase in donations in phase II (from 26 May 2020) stands out. Regarding consumption, there was a significant reduction in the consumption of packed red blood cells (RBCs) (24.5%), plasma (45.3%), and platelets (25.3%) in the central period (16 March–10 May). The reduction in the consumption of RBCs was significant in the period from 1–15 March. Conclusions: The COVID-19 pandemic has affected the donation and consumption of BCs. Keywords: COVID-19; transfusion; pandemic Author: José Antonio García-Erce, Íñigo Romón-Alonso, Carlos Jericó, José María Domingo-Morera, José Luis Arroyo-Rodríguez, Carlos Sola-Lapeña, José Luis Bueno-Cabrera, Raúl Juárez-Vela, Saioa Zalba-Marcos, Ane Abad-Motos, Vicente Gea-Caballero, Iván Santolalla-Arnedo and Manuel Quintana-Díaz Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Thu Apr 1 02:28:15 2021 CEST ModDate: Fri Apr 9 05:02:32 2021 CEST Custom Metadata: no Metadata Stream: no Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 16 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 1557564 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- ECFSJG+VnURWPalladioL Type 1 Custom yes yes no 10 0 RMBMVM+URWPalladioL-Ital Type 1 Custom yes yes no 15 0 WJRXGD+URWPalladioL-Bold Type 1 Custom yes yes no 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Title: Materials and Methods Destination: section.2 Children: Item: Title: Study Design Destination: subsection.2.1 Item: Title: Participants/Scope of the Study Destination: subsection.2.2 Item: Title: Period Studied Destination: subsection.2.3 Item: Title: Study Variables Destination: subsection.2.4 Item: Title: Data Collection Destination: subsection.2.5 Item: Title: Statistical Analysis Destination: subsection.2.6 Item: Title: Results Destination: section.3 Children: Item: Title: Activity in Spain Destination: subsection.3.1 Item: Title: Donations Destination: subsection.3.2 Item: Title: Distribution Destination: subsection.3.3 Item: Title: Consumption of Blood Components Destination: subsection.3.4 Item: Title: Shortage Destination: subsection.3.5 Item: Title: Hemovigilance Destination: subsection.3.6 Item: Title: Discussion Destination: section.4 Item: Title: Conclusions Destination: section.5 Item: Title: Destination: section.A. Item: Title: Destination: section.B. Item: Title: References Destination: figure.caption.13 Info: Title: Blood Donations and Transfusions during the COVID-19 Pandemic in Spain: Impact According to Autonomous Communities and Hospitals Author: José Antonio García-Erce, Íñigo Romón-Alonso, Carlos Jericó, José María Domingo-Morera, José Luis Arroyo-Rodríguez, Carlos Sola-Lapeña, José Luis Bueno-Cabrera, Raúl Juárez-Vela, Saioa Zalba-Marcos, Ane Abad-Motos, Vicente Gea-Caballero, Iván Santolalla-Arnedo and Manuel Quintana-Díaz Subject: Worldwide, the COVID-19 pandemic has caused a decline in blood donations, between 30% and 70% in some of the most affected countries. In Spain, during the initial eight weeks after the State of Emergency was decreed on 14 March 2020, in the weekly reports of the Health Ministry, an average decrease of 20% was observed between 11 and week 25 compared with the 2018 donation. We aimed to investigate the impact of the COVID-19 pandemic on blood donations and blood distribution in four autonomous communities, and to explore the evolution of the consumption of blood components (BCs) in ten hospitals of six autonomous communities. We performed a prospective study of grouped cohorts on the donation and distribution of blood in four regional transfusion centers in four autonomous communities in Spain, and a retrospective study of the consumption of blood components in ten hospitals in six autonomous communities. Regarding donations, there was no significant decrease in donations, with differences between autonomous communities, which started between 1 and 15 March 2020 (-11%). The increase in donations in phase II (from 26 May 2020) stands out. Regarding consumption, there was a significant reduction in the consumption of packed red blood cells (RBCs) (24.5%), plasma (45.3%), and platelets (25.3%) in the central period (16 March 10 May). The reduction in the consumption of RBCs was significant in the period from 1 15 March. Conclusions: The COVID-19 pandemic has affected the donation and consumption of BCs. 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