f055565ce72e84a88b1a5468696c4961 pmc_33807085.pdf e953343970038c3230aa41538bf71a144c7c4d57 pmc_33807085.pdf b28dcaf06265863fc232416c0066c7b4ebcd2ac497b2c2e01b6606577413eb2e pmc_33807085.pdf Title: The Effect of Perioperative Blood Transfusions on Microvascular Anastomoses Subject: Introduction: Perioperative transfusions are associated with complications of free flaps. The purpose of the present study was to find out whether there is a significant relationship between the risk of developing complications in vascular anastomoses and the history of transfusions. Methods: We studied 372 patients retrospectively with microsurgical reconstruction between 2009 and 2017 with regards to the number of red blood cell concentrates transfused. Complications were analyzed relative to flap loss and complications in microvascular anastomoses. Results: 130 patients (34.9%) received blood transfusions. Some 55% of them were transfused between the day of the intervention and the first postoperative day. Ninety-six patients were reoperated on (25.7%). Of those, thirty-six patients (37.5%) corresponded to anastomosis failure. The percentage of patients transfused among those who required reoperation was 55.2%. The percentage of patients transfused among those who were reoperated on within the first 72 h due to an alteration in the anastomosis was 60.6%, while it was 25.6% (Chi square P = 0.0001) for the rest of the patients. Conclusions: Although there is a strong association between transfusion and vascular anastomosis failure, it is not possible to establish the causation between the two. Keywords: microsurgery; transfusion; free flap; breast reconstruction Author: Lidia Sanchez-Porro Gil, Xavier Leon Vintro, Susana Lopez Fernandez, Carmen Vega Garcia, Gemma Pons Playa, Manuel Fernandez Garrido and Jaume Masia Ayala Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Tue Mar 23 16:31:13 2021 CET ModDate: Tue Mar 23 16:36:39 2021 CET Custom Metadata: no Metadata Stream: no Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 8 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 1060320 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- MIKRSI+VnURWPalladioL Type 1 Custom yes yes no 10 0 GHOHOB+URWPalladioL-Ital Type 1 Custom yes yes no 15 0 UUEQKR+URWPalladioL-Bold Type 1 Custom yes yes no 20 0 ZBRQEF+URWPalladioL-Roma Type 1 Custom yes yes no 24 0 XPUSBJ+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 32 0 BSDWLC+TimesNewRomanPSMT Type 1C WinAnsi yes yes no 35 0 MCBCCI+SourceSansRoman-Regular Type 1C Custom yes yes no 57 0 MCBCCM+SourceSansRoman.613wght Type 1C Custom yes yes no 61 0 MCBCCO+SourceSansRoman-Bold Type 1C Custom yes yes no 65 0 IJJHNK+TimesNewRoman,Bold CID TrueType Identity-H yes yes yes 83 0 IJJICK+DengXian CID TrueType Identity-H yes yes yes 89 0 IJJGPI+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 95 0 IJJHAI+TimesNewRoman CID TrueType Identity-H yes yes yes 98 0 IJJHAK+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 104 0 IJJHAM+PalatinoLinotype TrueType WinAnsi yes yes no 107 0 IJJHNJ+TimesNewRoman,Italic TrueType WinAnsi yes yes no 110 0 IJJHNK+TimesNewRoman,Bold CID TrueType Identity-H yes yes yes 120 0 IJJGPI+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 126 0 IJJHAI+TimesNewRoman CID TrueType Identity-H yes yes yes 129 0 IJJHAK+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 135 0 IJJHAM+PalatinoLinotype TrueType WinAnsi yes yes no 138 0 IJJHNJ+TimesNewRoman,Italic TrueType WinAnsi yes yes no 141 0 IJJHNK+TimesNewRoman,Bold CID TrueType Identity-H yes yes yes 158 0 IJJGPI+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 164 0 IJJHAI+TimesNewRoman CID TrueType Identity-H yes yes yes 167 0 IJJHAK+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 173 0 IJJHAM+PalatinoLinotype TrueType WinAnsi yes yes no 176 0 IJJHNJ+TimesNewRoman,Italic TrueType WinAnsi yes yes no 179 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-10-02 03:24:26 CEST RepresentationInformation: pmc_33807085.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2023-03-31 12:09:33 CEST Size: 1060320 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 295 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: section.1 Item: Title: Patients and Methods Destination: section.2 Children: Item: Title: Parameters Evaluated Destination: subsection.2.1 Item: Title: Statistical Analysis Destination: subsection.2.2 Item: Title: Results Destination: section.3 Children: Item: Title: Overall Results Destination: subsection.3.1 Item: Title: Transfusion Requirements Destination: subsection.3.2 Item: Title: Relationship between Transfusion and Complications Destination: subsection.3.3 Item: Title: Duration of Surgery Destination: subsection.3.4 Item: Title: Discussion Destination: section.4 Item: Title: Conclusions Destination: section.5 Item: Title: References Destination: section.5 Info: Title: The Effect of Perioperative Blood Transfusions on Microvascular Anastomoses Author: Lidia Sanchez-Porro Gil, Xavier Leon Vintro, Susana Lopez Fernandez, Carmen Vega Garcia, Gemma Pons Playa, Manuel Fernandez Garrido and Jaume Masia Ayala Subject: Introduction: Perioperative transfusions are associated with complications of free flaps. The purpose of the present study was to find out whether there is a significant relationship between the risk of developing complications in vascular anastomoses and the history of transfusions. Methods: We studied 372 patients retrospectively with microsurgical reconstruction between 2009 and 2017 with regards to the number of red blood cell concentrates transfused. Complications were analyzed relative to flap loss and complications in microvascular anastomoses. Results: 130 patients (34.9%) received blood transfusions. Some 55% of them were transfused between the day of the intervention and the first postoperative day. Ninety-six patients were reoperated on (25.7%). Of those, thirty-six patients (37.5%) corresponded to anastomosis failure. The percentage of patients transfused among those who required reoperation was 55.2%. The percentage of patients transfused among those who were reoperated on within the first 72 h due to an alteration in the anastomosis was 60.6%, while it was 25.6% (Chi square P = 0.0001) for the rest of the patients. Conclusions: Although there is a strong association between transfusion and vascular anastomosis failure, it is not possible to establish the causation between the two. Keywords: microsurgery; transfusion; free flap; breast reconstruction Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Tue Mar 23 16:31:13 CET 2021 ModDate: Tue Mar 23 16:36:39 CET 2021 ID: 0xa2c7eb9faef5edb546580f640e758cdd, 0xa2c7eb9faef5edb546580f640e758cdd Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: UUEQKR+URWPalladioL-Bold FontSubset: true FirstChar: 3 LastChar: 122 FontDescriptor: FontName: UUEQKR+URWPalladioL-Bold Flags: Symbolic FontBBox: -152, -301, 1000, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: ZBRQEF+URWPalladioL-Roma FontSubset: true FirstChar: 2 LastChar: 169 FontDescriptor: FontName: ZBRQEF+URWPalladioL-Roma Flags: Symbolic FontBBox: -166, -283, 1021, 943 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: MIKRSI+VnURWPalladioL FontSubset: true FirstChar: 225 LastChar: 225 FontDescriptor: FontName: MIKRSI+VnURWPalladioL Flags: Symbolic FontBBox: -166, -283, 1021, 943 FontFile: true 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