b4ce29b8ba580e29c6eaecafa30c6327 255490.pdf 55a29b21b32fd98d5e4359e6792bb23aa6717cd2 255490.pdf aefaf901c71a66fa6876f74117c238d478366c6ba8e26b930f864f5dcad01d0e 255490.pdf Title: Engaging Spinal Networks to Mitigate Supraspinal Dysfunction After CP Subject: Although children with cerebral palsy seem to have the neural networks necessary to generate most movements, they are markedly dysfunctional, largely attributable to abnormal patterns of muscle activation, often characterized as spasticity, largely reflecting a functionally abnormal spinal-supraspinal connectivity. Keywords: cerebral palsy, spinal cord, brain, muscle, EMG Author: Parag N. Gad Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.15 CreationDate: Mon Apr 5 07:06:39 2021 CEST ModDate: Mon Apr 5 14:49:01 2021 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 5 Encrypted: no Page size: 595.276 x 779.528 pts Page rot: 0 File size: 909765 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- WUYHDH+MinionPro-Regular Type 1 Custom yes yes no 27 0 HHMHTP+HelveticaNeueLTStd-Bd Type 1 Custom yes yes no 28 0 GPOSPW+HelveticaNeueLTStd-Lt Type 1 Custom yes yes no 29 0 CCVXXJ+HelveticaNeueLTStd-BdIt Type 1 Custom yes yes no 34 0 OXFYDA+HelveticaNeueLTStd-LtIt Type 1 Custom yes yes no 35 0 EDKRMV+HelveticaNeueLTStd-MdIt Type 1 Custom yes yes no 36 0 ZOXGSI+MinionPro-Bold Type 1 Custom yes yes no 176 0 KGSVVL+MinionPro-It Type 1 Custom yes yes no 275 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-09-23 02:35:03 CEST RepresentationInformation: 255490.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-09-22 12:19:51 CEST Size: 909765 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 0 FreeObjects: 8 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Engaging Spinal Networks to Mitigate Supraspinal Dysfunction After CP Children: Item: Title: The Problem Item: Title: Solution Item: Title: Testing the Hypothesis Item: Title: Disclosure Item: Title: Data Availability Statement Item: Title: Author Contributions Item: Title: Funding Item: Title: References Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: ZOXGSI+MinionPro-Bold FontSubset: true FirstChar: 3 LastChar: 117 FontDescriptor: FontName: ZOXGSI+MinionPro-Bold Flags: Symbolic FontBBox: -318, -360, 1684, 917 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: CCVXXJ+HelveticaNeueLTStd-BdIt FontSubset: true FirstChar: 42 LastChar: 121 FontDescriptor: FontName: CCVXXJ+HelveticaNeueLTStd-BdIt Flags: Symbolic FontBBox: -166, -218, 1129, 975 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: OXFYDA+HelveticaNeueLTStd-LtIt FontSubset: true FirstChar: 40 LastChar: 243 FontDescriptor: FontName: OXFYDA+HelveticaNeueLTStd-LtIt Flags: Symbolic FontBBox: -165, -214, 1099, 951 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: KGSVVL+MinionPro-It FontSubset: true FirstChar: 3 LastChar: 169 FontDescriptor: FontName: KGSVVL+MinionPro-It Flags: Symbolic FontBBox: -201, -360, 1684, 919 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: EDKRMV+HelveticaNeueLTStd-MdIt FontSubset: true FirstChar: 42 LastChar: 117 FontDescriptor: FontName: EDKRMV+HelveticaNeueLTStd-MdIt Flags: Symbolic FontBBox: -165, -218, 1125, 947 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: WUYHDH+MinionPro-Regular FontSubset: true FirstChar: 2 LastChar: 150 FontDescriptor: FontName: WUYHDH+MinionPro-Regular Flags: Symbolic FontBBox: -289, -360, 1684, 917 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: HHMHTP+HelveticaNeueLTStd-Bd FontSubset: true FirstChar: 40 LastChar: 124 FontDescriptor: FontName: HHMHTP+HelveticaNeueLTStd-Bd Flags: Symbolic FontBBox: -166, -218, 1078, 975 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: GPOSPW+HelveticaNeueLTStd-Lt FontSubset: true FirstChar: 2 LastChar: 124 FontDescriptor: FontName: GPOSPW+HelveticaNeueLTStd-Lt Flags: Symbolic FontBBox: -166, -214, 1050, 967 FontFile: true EncodingDictionary: Differences: true XMP: cerebral palsy, spinal cord, brain, muscle, EMG pdfTeX-1.40.15 1.5 application/pdf fnins-15-643463.tex Engaging Spinal Networks to Mitigate Supraspinal Dysfunction After CP Although children with cerebral palsy seem to have the neural networks necessary to generate most movements, they are markedly dysfunctional, largely attributable to abnormal patterns of muscle activation, often characterized as spasticity, largely reflecting a functionally abnormal spinal-supraspinal connectivity. Parag N. 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