47bbfa173d87cd81de267f2950467ef9 pmc_33919520.pdf 05fa2ebe87a4c31cd6af921ceadf5e804560c223 pmc_33919520.pdf 1673026fcd836550af1b3cf184e2b595cd837bf2c64578ca381a0973f9118647 pmc_33919520.pdf Title: Is It Safe to Combine a Fundoplication to Sleeve Gastrectomy? Review of Literature Subject: Background and Objectives: The rising numbers of laparoscopic sleeve gastrectomy (LSG) procedures now being performed worldwide will likely be followed by an increasing number of patients experiencing gastro-esophageal reflux disease (GERD). The purpose of the current review was to analyze in terms of safety different techniques of fundoplication used to treat GERD associated with LSG. Methods: An online search was performed in PubMed/MEDLINE in December 2020 to identify articles reporting LSG and fundoplication. The following term combination was used: (sleeve, fundoplication), (sleeve, Nissen), (sleeve, Rossetti), (sleeve, Toupet) and (sleeve, Dor). The extracted information included details of the methods (e.g., retrospective case series), demographic characteristics (e.g., age, gender), clinical characteristics, number of patients, rate of conversion, and postoperative outcomes. Results: A total of 154 studies were identified and after an assessment of title according to our exclusion criteria, 116 articles were removed. Of the 38 studies analyzed for full content review, a total of seven primary studies (487 patients) were identified with all inclusion criteria. Analyzing the different types of fundoplication used, we have identified: 236 cases of Nissen-Sleeve, 220 cases with modified Rossetti fundoplication, 31 cases of Dor fundoplication, and no case of Toupet fundoplication. The overall postoperative complication rate was 9.4%, with the most common reported complication being gastric perforation, 15 cases—3.1%. The second most common complication was bleeding identified in nine cases (1.8%) followed by gastric stenosis in six cases (1.2%). The mortality was nil. Conclusions: Different types of fundoplication associated with LSG appear to be a safe surgical technique with an acceptable early postoperative complication rate. Any type of fundoplication associated with LSG to decrease GERD should be evaluated cautiously while prospective clinical randomized trials are needed. Keywords: sleeve; GERD; fundoplication; Nissen; Rossetti; Dor; complications Author: Sergio Carandina, Viola Zulian, Anamaria Nedelcu, Marc Danan, Ramon Vilallonga, David Nocca and Marius Nedelcu Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Sun Apr 18 10:17:06 2021 CEST ModDate: Sun Apr 18 10:39:04 2021 CEST Custom Metadata: no Metadata Stream: no Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 7 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 584671 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- CIQLLF+VnURWPalladioL Type 1 Custom yes yes no 10 0 ITHTVP+URWPalladioL-Ital Type 1 Custom yes yes no 15 0 QTQEJB+URWPalladioL-Bold Type 1 Custom yes yes no 20 0 KAWYYD+URWPalladioL-Roma Type 1 Custom yes yes no 24 0 HVRRJG+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 32 0 MCBCCI+SourceSansRoman-Regular Type 1C Custom yes yes no 49 0 MCBCCM+SourceSansRoman.613wght Type 1C Custom yes yes no 53 0 MCBCCO+SourceSansRoman-Bold Type 1C Custom yes yes no 57 0 XYPWHM+CMSY10 Type 1 Builtin yes yes no 69 0 BCDEEE+PalatinoLinotype-Bold TrueType WinAnsi yes yes no 84 0 BCDFEE+PalatinoLinotype-Roman TrueType WinAnsi yes yes no 88 0 BCDGEE+PalatinoLinotype-Italic TrueType WinAnsi yes yes no 92 0 BCDHEE+PalatinoLinotype-Roman CID TrueType Identity-H yes yes yes 96 0 ArialMT TrueType WinAnsi no no no 103 0 BCDJEE+Calibri TrueType WinAnsi yes yes no 106 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-10-02 03:20:43 CEST RepresentationInformation: pmc_33919520.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2023-03-31 12:09:47 CEST Size: 584671 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 231 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: section.1 Item: Title: Materials and Methods Destination: section.2 Children: Item: Title: Search Strategy and Study Selection Destination: subsection.2.1 Item: Title: Data Extraction and Management Destination: subsection.2.2 Item: Title: Statistical Analysis Destination: subsection.2.3 Item: Title: Results Destination: section.3 Children: Item: Title: Search Results Destination: subsection.3.1 Item: Title: Included Studies Destination: subsection.3.2 Item: Title: Discussion Destination: section.4 Item: Title: Conclusions Destination: section.5 Item: Title: References Destination: section.5 Info: Title: Is It Safe to Combine a Fundoplication to Sleeve Gastrectomy? Review of Literature Author: Sergio Carandina, Viola Zulian, Anamaria Nedelcu, Marc Danan, Ramon Vilallonga, David Nocca and Marius Nedelcu Subject: Background and Objectives: The rising numbers of laparoscopic sleeve gastrectomy (LSG) procedures now being performed worldwide will likely be followed by an increasing number of patients experiencing gastro-esophageal reflux disease (GERD). The purpose of the current review was to analyze in terms of safety different techniques of fundoplication used to treat GERD associated with LSG. Methods: An online search was performed in PubMed/MEDLINE in December 2020 to identify articles reporting LSG and fundoplication. The following term combination was used: (sleeve, fundoplication), (sleeve, Nissen), (sleeve, Rossetti), (sleeve, Toupet) and (sleeve, Dor). The extracted information included details of the methods (e.g., retrospective case series), demographic characteristics (e.g., age, gender), clinical characteristics, number of patients, rate of conversion, and postoperative outcomes. Results: A total of 154 studies were identified and after an assessment of title according to our exclusion criteria, 116 articles were removed. Of the 38 studies analyzed for full content review, a total of seven primary studies (487 patients) were identified with all inclusion criteria. Analyzing the different types of fundoplication used, we have identified: 236 cases of Nissen-Sleeve, 220 cases with modified Rossetti fundoplication, 31 cases of Dor fundoplication, and no case of Toupet fundoplication. The overall postoperative complication rate was 9.4%, with the most common reported complication being gastric perforation, 15 cases 3.1%. The second most common complication was bleeding identified in nine cases (1.8%) followed by gastric stenosis in six cases (1.2%). The mortality was nil. Conclusions: Different types of fundoplication associated with LSG appear to be a safe surgical technique with an acceptable early postoperative complication rate. Any type of fundoplication associated with LSG to decrease GERD should be evaluated cautiously while prospective clinical randomized trials are needed. Keywords: sleeve; GERD; fundoplication; Nissen; Rossetti; Dor; complications Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Sun Apr 18 10:17:06 CEST 2021 ModDate: Sun Apr 18 10:39:04 CEST 2021 ID: 0xd300b4bd1ce722f49823bb19b63b9fc8, 0xd300b4bd1ce722f49823bb19b63b9fc8 Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: QTQEJB+URWPalladioL-Bold FontSubset: true FirstChar: 3 LastChar: 121 FontDescriptor: FontName: QTQEJB+URWPalladioL-Bold Flags: Symbolic FontBBox: -152, -301, 1000, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: XYPWHM+CMSY10 FontSubset: true FirstChar: 0 LastChar: 14 FontDescriptor: FontName: XYPWHM+CMSY10 Flags: Symbolic FontBBox: -29, -960, 1116, 775 FontFile: true Font: BaseFont: KAWYYD+URWPalladioL-Roma FontSubset: true FirstChar: 2 LastChar: 252 FontDescriptor: FontName: KAWYYD+URWPalladioL-Roma Flags: Symbolic FontBBox: -166, -283, 1021, 943 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: CIQLLF+VnURWPalladioL FontSubset: true FirstChar: 161 LastChar: 226 FontDescriptor: FontName: CIQLLF+VnURWPalladioL Flags: Symbolic FontBBox: -166, -283, 1021, 943 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: ITHTVP+URWPalladioL-Ital FontSubset: true FirstChar: 46 LastChar: 121 FontDescriptor: FontName: ITHTVP+URWPalladioL-Ital Flags: Symbolic FontBBox: -170, -305, 1010, 941 FontFile: true EncodingDictionary: Differences: true Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 35, 759, 178, 795 Annotation: Subtype: Link Rect: 515, 759, 560, 795 Annotation: Subtype: Link Rect: 107, 346, 154, 355 Annotation: Subtype: Link Rect: 35, 334, 146, 343 Annotation: Subtype: Link Rect: 35, 162, 97, 184 Annotation: Subtype: Link Rect: 153, 89, 154, 98 Annotation: Subtype: Link Rect: 35, 77, 147, 86 Annotation: Subtype: Link Rect: 354, 130, 361, 139 ActionDest: 113 Annotation: Subtype: Link Rect: 364, 130, 371, 139 ActionDest: 113 Annotation: Subtype: Link Rect: 398, 105, 405, 114 ActionDest: 113 Annotation: Subtype: Link Rect: 115, 17, 272, 28 Annotation: Subtype: Link Rect: 402, 17, 558, 28 Annotation: Subtype: Link Rect: 35, 423, 87, 442 Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 205, 699, 212, 708 ActionDest: 113 Annotation: Subtype: Link Rect: 215, 699, 222, 708 ActionDest: 113 Annotation: Subtype: Link Rect: 200, 624, 212, 633 ActionDest: 113 Annotation: Subtype: Link Rect: 497, 596, 504, 608 ActionDest: 66 Annotation: Subtype: Link Rect: 508, 599, 520, 608 ActionDest: 113 Annotation: Subtype: Link Rect: 523, 598, 535, 608 ActionDest: 113 Annotation: Subtype: Link Rect: 57, 424, 65, 430 ActionDest: 113 Annotation: Subtype: Link Rect: 57, 397, 65, 404 ActionDest: 113 Annotation: Subtype: Link Rect: 57, 371, 65, 378 ActionDest: 113 Annotation: Subtype: Link Rect: 57, 339, 65, 346 ActionDest: 113 Annotation: Subtype: Link Rect: 57, 307, 65, 313 ActionDest: 113 Annotation: Subtype: Link Rect: 57, 274, 65, 280 ActionDest: 113 Annotation: Subtype: Link Rect: 57, 242, 65, 249 ActionDest: 113 Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 319, 344, 331, 353 ActionDest: 113 Annotation: Subtype: Link Rect: 407, 281, 419, 290 ActionDest: 113 Annotation: Subtype: Link Rect: 422, 281, 434, 290 ActionDest: 116 Annotation: Subtype: Link Rect: 202, 268, 214, 278 ActionDest: 116 Annotation: Subtype: Link Rect: 217, 268, 229, 278 ActionDest: 116 Annotation: Subtype: Link Rect: 464, 268, 476, 278 ActionDest: 116 Annotation: Subtype: Link Rect: 479, 268, 491, 278 ActionDest: 116 Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 545, 720, 552, 732 ActionDest: 76 Annotation: Subtype: Link Rect: 199, 254, 211, 263 ActionDest: 116 Annotation: Subtype: Link Rect: 211, 254, 223, 263 ActionDest: 116 Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 411, 584, 423, 593 ActionDest: 113 Annotation: Subtype: Link Rect: 424, 584, 436, 593 ActionDest: 113 Annotation: Subtype: Link Rect: 436, 584, 448, 593 ActionDest: 113 Annotation: Subtype: Link Rect: 346, 572, 358, 581 ActionDest: 113 Annotation: Subtype: Link Rect: 359, 572, 371, 581 ActionDest: 113 Annotation: Subtype: Link Rect: 253, 534, 265, 543 ActionDest: 116 Annotation: Subtype: Link Rect: 265, 534, 277, 543 ActionDest: 116 Annotation: Subtype: Link Rect: 278, 534, 289, 543 ActionDest: 116 Annotation: Subtype: Link Rect: 268, 522, 280, 530 ActionDest: 116 Annotation: Subtype: Link Rect: 544, 509, 556, 518 ActionDest: 116 Annotation: Subtype: Link Rect: 543, 308, 555, 317 ActionDest: 116 Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 196, 585, 233, 595 Annotation: Subtype: Link Rect: 104, 550, 141, 560 Annotation: Subtype: Link Rect: 412, 526, 450, 537 Annotation: Subtype: Link Rect: 456, 526, 492, 537 Annotation: Subtype: Link Rect: 430, 492, 467, 503 Annotation: Subtype: Link Rect: 474, 492, 510, 503 Annotation: Subtype: Link Rect: 291, 469, 328, 480 Annotation: Subtype: Link Rect: 59, 435, 97, 445 Annotation: Subtype: Link Rect: 173, 401, 210, 411 Annotation: Subtype: Link Rect: 217, 401, 253, 411 Annotation: Subtype: Link Rect: 109, 366, 146, 376 Annotation: Subtype: Link Rect: 152, 366, 188, 376 Annotation: Subtype: Link Rect: 262, 331, 300, 342 Annotation: Subtype: Link Rect: 144, 309, 182, 319 Annotation: Subtype: Link Rect: 188, 309, 224, 319 Annotation: Subtype: Link Rect: 519, 285, 557, 296 Annotation: Subtype: Link Rect: 59, 274, 95, 284 Annotation: Subtype: Link Rect: 270, 250, 308, 261 Annotation: Subtype: Link Rect: 275, 227, 312, 238 Annotation: Subtype: Link Rect: 292, 204, 330, 215 Annotation: Subtype: Link Rect: 336, 204, 372, 215 Annotation: Subtype: Link Rect: 382, 181, 419, 192 Annotation: Subtype: Link Rect: 140, 147, 178, 158 Annotation: Subtype: Link Rect: 292, 124, 329, 135 Annotation: Subtype: Link Rect: 104, 90, 141, 100 Annotation: Subtype: Link Rect: 148, 90, 184, 100 Annotation: Subtype: Link Rect: 470, 66, 507, 77 Annotation: Subtype: Link Rect: 513, 66, 549, 77 Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 317, 709, 354, 720 Annotation: Subtype: Link Rect: 59, 676, 97, 686 Annotation: Subtype: Link Rect: 59, 641, 97, 651 Annotation: Subtype: Link Rect: 411, 617, 448, 628 Annotation: Subtype: Link Rect: 59, 584, 97, 594 Annotation: Subtype: Link Rect: 385, 560, 422, 571 Annotation: Subtype: Link Rect: 385, 537, 423, 548 Annotation: Subtype: Link Rect: 429, 537, 465, 548 Annotation: Subtype: Link Rect: 402, 514, 440, 525 Annotation: Subtype: Link Rect: 446, 514, 482, 525 Annotation: Subtype: Link Rect: 418, 491, 456, 502 Annotation: Subtype: Link Rect: 462, 491, 498, 502 Annotation: Subtype: Link Rect: 59, 469, 97, 479 Annotation: Subtype: Link Rect: 431, 445, 469, 456 Annotation: Subtype: Link Rect: 519, 433, 557, 444 Annotation: Subtype: Link Rect: 59, 423, 95, 433 Annotation: Subtype: Link Rect: 331, 399, 368, 410 Annotation: Subtype: Link Rect: 374, 399, 410, 410 Annotation: Subtype: Link Rect: 59, 365, 97, 375 Annotation: Subtype: Link Rect: 103, 365, 139, 375 Annotation: Subtype: Link Rect: 397, 341, 435, 352 Annotation: Subtype: Link Rect: 441, 341, 477, 352 Annotation: Subtype: Link Rect: 499, 330, 537, 341 Annotation: Subtype: Link Rect: 424, 307, 462, 318 Checksum: 4466828d Type: CRC32 Checksum: 47bbfa173d87cd81de267f2950467ef9 Type: MD5 Checksum: 05fa2ebe87a4c31cd6af921ceadf5e804560c223 Type: SHA-1 Checksum: 1673026fcd836550af1b3cf184e2b595cd837bf2c64578ca381a0973f9118647 Type: SHA-256