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Title:           Variability in porcine microRNA genes and its association with mRNA expression and lipid phenotypes
Subject:         Genetics Selection Evolution, https://doi.org/10.1186/s12711-021-00632-3
Author:          Emilio Mármol-Sánchez 
Creator:         Springer
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     Item: 
      Title: Variability in porcine microRNA genes and its association with mRNA expression and lipid phenotypes
      Children: 
       Item: 
        Title: Abstract 
        Children: 
         Item: 
          Title: Background: 
         Item: 
          Title: Results: 
         Item: 
          Title: Conclusions: 
       Item: 
        Title: Background
       Item: 
        Title: Methods
        Children: 
         Item: 
          Title: Characterization of polymorphisms in miRNA genes and their 3′UTR binding sites in a worldwide sample of pigs and wild boars
          Children: 
           Item: 
            Title: Retrieval of porcine whole-genome sequences
           Item: 
            Title: Whole-genome sequence data processing and calling of single nucleotide polymorphisms
           Item: 
            Title: Identification of single nucleotide polymorphisms in miRNA genes and in their 3′UTR binding sites
           Item: 
            Title: Frequency and distribution of SNPs in miRNA genes
         Item: 
          Title: Investigating the association of miRNA polymorphisms with gene expression and phenotype data recorded in Duroc pigs
          Children: 
           Item: 
            Title: Whole-genome sequencing of five Duroc pigs
           Item: 
            Title: Recording of phenotypes related with gene expression and lipid traits in the Lipgen population
           Item: 
            Title: Genotyping of a panel of single nucleotide polymorphisms mapping to microRNA genes in the Lipgen population
           Item: 
            Title: Association analyses between miRNA SNPs and mRNA expression and lipid phenotypes
           Item: 
            Title: Pathway enrichment analysis
           Item: 
            Title: Confirmation of associations between ssc-miR-326 rs319154814 genotypes and gene expression data by RT-qPCR
           Item: 
            Title: Measurement of the expression of the ssc-miR-326 gene in pigs with different rs319154814 genotypes
       Item: 
        Title: Results
        Children: 
         Item: 
          Title: Differential segregation of SNPs mapping to microRNA genes in pigs and wild boars from Europe and Asia
         Item: 
          Title: Analysis of European and Asian populations shows reduced variability in porcine microRNAs
         Item: 
          Title: Statistics of the whole-genome sequencing of five Duroc boars and association analyses
         Item: 
          Title: Two SNPs in the apical loop of ssc-miR-326 and in the precursor region of ssc-miR-23a are associated with the mRNA expression of several of their putative targets
         Item: 
          Title: Pathway enrichment analyses of significantly associated mRNA targets provide insights of putative metabolic functions of miRNAs
         Item: 
          Title: Porcine lipid phenotypes are associated with the genotypes of miRNA genes
       Item: 
        Title: Discussion
        Children: 
         Item: 
          Title: Divergent patterns of variation for microRNA and 3′UTR polymorphisms in Asian and European pigs and wild boars
         Item: 
          Title: Low SNP density in microRNA genes and lack of uniform SNP distribution across sites
         Item: 
          Title: Polymorphisms in microRNA genes show associations with the mRNA expression of several of their predicted targets
         Item: 
          Title: A polymorphism in the apical loop of microRNA 326 is associated with fatty acid composition traits
       Item: 
        Title: Conclusions
       Item: 
        Title: References
   Info: 
    Title: Variability in porcine microRNA genes and its association with mRNA expression and lipid phenotypes
    Author: Emilio Mármol-Sánchez 
    Subject: Genetics Selection Evolution, https://doi.org/10.1186/s12711-021-00632-3
    Creator: Springer
    Producer: iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version)
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