47c9835aebb3a7f76c9867956fef3c5c pmc_33953263.pdf 851e2f135bdf5e45d5443a2f84b7bd9a364ec343 pmc_33953263.pdf 76c1b3f10cbedd1b1e548dfb191e803f70f825468a116c2f17227513fd0845db pmc_33953263.pdf Title: On Gaussian curvature and membrane fission Subject: Scientific Reports, https://doi.org/10.1038/s41598-021-88851-y Author: Mara Denisse Rueda-Contreras Creator: Springer Producer: Adobe PDF Library 15.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Thu Apr 29 09:14:07 2021 CEST ModDate: Thu Apr 29 11:19:54 2021 CEST Custom Metadata: yes Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 10 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 1664284 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- KYGFLE+Wingdings-Regular Type 1C WinAnsi yes yes yes 1561 0 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Outlines: Item: Title: On Gaussian curvature and membrane fission Children: Item: Title: Methods Children: Item: Title: The model. Item: Title: Results Children: Item: Title: Numerical simulations. Item: Title: Discussion Item: Title: References Item: Title: Acknowledgements Info: Title: On Gaussian curvature and membrane fission Author: Mara Denisse Rueda-Contreras Subject: Scientific Reports, https://doi.org/10.1038/s41598-021-88851-y Creator: Springer Producer: Adobe PDF Library 15.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Thu Apr 29 09:44:07 CEST 2021 ModDate: Thu Apr 29 11:19:54 CEST 2021 ID: 0x7c637bdb960d7fe29e2594cae6f1925d, 0x7c6551ecd2296495cb9efbde8a8670eb Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1004 ImageHeight: 1169 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1004 ImageHeight: 595 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: 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EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MinionPro-Regular FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MinionPro-Regular Flags: Serif, Nonsymbolic FontBBox: -290, -360, 1684, 989 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MTMI29 FontSubset: true FirstChar: 30 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTMI29 Flags: Symbolic FontBBox: 0, -207, 727, 676 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MTSYN4 FontSubset: true FirstChar: 31 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTSYN4 Flags: Symbolic FontBBox: 0, -954, 987, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: LVKLEW+MinionPro-It32 FontSubset: true FirstChar: 31 LastChar: 33 FontDescriptor: FontName: LVKLEW+MinionPro-It32 Flags: 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LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular24 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: LVKLEW+MinionPro-It31 FontSubset: true FirstChar: 31 LastChar: 31 FontDescriptor: FontName: LVKLEW+MinionPro-It31 Flags: Symbolic, AllCap FontBBox: 0, -15, 652, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MinionPro-Regular11 FontSubset: true FirstChar: 29 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular11 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MinionPro-Regular31 FontSubset: true FirstChar: 30 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular31 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding 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FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTMI15 FontSubset: true FirstChar: 29 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTMI15 Flags: Symbolic FontBBox: 0, -207, 727, 676 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MTMI34 FontSubset: true FirstChar: 29 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTMI34 Flags: Symbolic FontBBox: 0, -207, 727, 676 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: BRAMUQ+CMEX103 FontSubset: true FirstChar: 27 LastChar: 33 FontDescriptor: FontName: BRAMUQ+CMEX103 Flags: Symbolic FontBBox: 0, -2359, 1387, 40 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTSYN33 FontSubset: true FirstChar: 29 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTSYN33 Flags: Symbolic FontBBox: 0, -954, 987, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MinionPro-Regular5 FontSubset: true FirstChar: 31 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular5 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTSYN7 FontSubset: true FirstChar: 30 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTSYN7 Flags: Symbolic FontBBox: 0, -954, 987, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MinionPro-It11 FontSubset: true FirstChar: 30 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-It11 Flags: Symbolic FontBBox: -1, -252, 780, 712 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTMI7 FontSubset: true FirstChar: 30 LastChar: 33 FontDescriptor: FontName: 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WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MTSYN14 FontSubset: true FirstChar: 30 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTSYN14 Flags: Symbolic FontBBox: 0, -954, 987, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: QQNYWM+TimesMath-LightScript5 FontSubset: true FirstChar: 30 LastChar: 33 FontDescriptor: FontName: QQNYWM+TimesMath-LightScript5 Flags: Symbolic, AllCap FontBBox: 0, -13, 968, 686 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MinionPro-It9 FontSubset: true FirstChar: 28 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-It9 Flags: Symbolic FontBBox: -1, -252, 780, 712 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MinionPro-Regular32 FontSubset: true FirstChar: 31 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular32 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: LVKLEW+MinionPro-It31 FontSubset: true FirstChar: 31 LastChar: 31 FontDescriptor: FontName: LVKLEW+MinionPro-It31 Flags: Symbolic, AllCap FontBBox: 0, -15, 652, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTSYN34 FontSubset: true FirstChar: 29 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTSYN34 Flags: Symbolic FontBBox: 0, -954, 987, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MTSYN35 FontSubset: true FirstChar: 29 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTSYN35 Flags: Symbolic FontBBox: 0, -954, 987, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MinionPro-Regular34 FontSubset: true FirstChar: 29 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular34 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTMI36 FontSubset: true FirstChar: 30 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTMI36 Flags: Symbolic FontBBox: 0, -207, 727, 676 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: LVKLEW+MinionPro-It34 FontSubset: true FirstChar: 31 LastChar: 33 FontDescriptor: FontName: LVKLEW+MinionPro-It34 Flags: Symbolic, AllCap FontBBox: 0, -15, 652, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MinionPro-Regular35 FontSubset: true FirstChar: 29 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular35 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MinionPro-Regular33 FontSubset: true FirstChar: 30 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular33 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: VSITOC+Arial-ItalicMT FontSubset: true FirstChar: 32 LastChar: 113 FontDescriptor: FontName: VSITOC+Arial-ItalicMT Flags: Nonsymbolic FontBBox: -517, -325, 1359, 998 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: VSITOC+Symbol FontSubset: true FirstChar: 31 LastChar: 33 FontDescriptor: FontName: VSITOC+Symbol Flags: Symbolic FontBBox: -180, -293, 1090, 1010 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MinionPro-Regular36 FontSubset: true FirstChar: 29 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular36 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTMI37 FontSubset: true FirstChar: 31 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTMI37 Flags: Symbolic FontBBox: 0, -207, 727, 676 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MinionPro-Regular37 FontSubset: true FirstChar: 31 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular37 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTSYN36 FontSubset: true FirstChar: 30 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTSYN36 Flags: Symbolic FontBBox: 0, -954, 987, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MTMI39 FontSubset: true FirstChar: 30 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTMI39 Flags: Symbolic FontBBox: 0, -207, 727, 676 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTMI38 FontSubset: true FirstChar: 30 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTMI38 Flags: Symbolic FontBBox: 0, -207, 727, 676 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MinionPro-Regular44 FontSubset: true FirstChar: 28 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular44 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTSYN37 FontSubset: true FirstChar: 31 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTSYN37 Flags: Symbolic FontBBox: 0, -954, 987, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: FULBYI+RMTMIB FontSubset: true FirstChar: 31 LastChar: 33 FontDescriptor: FontName: FULBYI+RMTMIB Flags: Symbolic FontBBox: 0, -200, 583, 686 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTSYN44 FontSubset: true FirstChar: 28 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTSYN44 Flags: Symbolic FontBBox: 0, -954, 987, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MTMI47 FontSubset: true FirstChar: 24 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTMI47 Flags: Symbolic FontBBox: 0, -207, 727, 676 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: BRAMUQ+CMEX1013 FontSubset: true FirstChar: 28 LastChar: 33 FontDescriptor: FontName: BRAMUQ+CMEX1013 Flags: Symbolic FontBBox: 0, -2359, 1387, 40 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MinionPro-Regular45 FontSubset: true FirstChar: 28 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular45 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTSYN43 FontSubset: true FirstChar: 26 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTSYN43 Flags: Symbolic FontBBox: 0, -954, 987, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MTSYN42 FontSubset: true FirstChar: 26 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTSYN42 Flags: Symbolic FontBBox: 0, -954, 987, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MinionPro-Regular43 FontSubset: true FirstChar: 30 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular43 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTMI45 FontSubset: true FirstChar: 24 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTMI45 Flags: Symbolic FontBBox: 0, -207, 727, 676 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MinionPro-Regular41 FontSubset: true FirstChar: 29 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular41 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTMI46 FontSubset: true FirstChar: 24 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTMI46 Flags: Symbolic FontBBox: 0, -207, 727, 676 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MTMI42 FontSubset: true FirstChar: 29 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTMI42 Flags: Symbolic FontBBox: 0, -207, 727, 676 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: BRAMUQ+CMEX1012 FontSubset: true FirstChar: 28 LastChar: 33 FontDescriptor: FontName: BRAMUQ+CMEX1012 Flags: Symbolic FontBBox: 0, -2359, 1387, 40 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MinionPro-Regular42 FontSubset: true FirstChar: 26 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular42 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTMI48 FontSubset: true FirstChar: 29 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTMI48 Flags: Symbolic FontBBox: 0, -207, 727, 676 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MTSYN41 FontSubset: true FirstChar: 27 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTSYN41 Flags: Symbolic FontBBox: 0, -954, 987, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MTMI44 FontSubset: true FirstChar: 25 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTMI44 Flags: Symbolic FontBBox: 0, -207, 727, 676 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MTMI43 FontSubset: true FirstChar: 26 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTMI43 Flags: Symbolic FontBBox: 0, -207, 727, 676 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MinionPro-Regular39 FontSubset: true FirstChar: 28 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular39 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTSYN39 FontSubset: true FirstChar: 27 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTSYN39 Flags: Symbolic FontBBox: 0, -954, 987, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MinionPro-Regular40 FontSubset: true FirstChar: 31 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular40 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MinionPro-It35 FontSubset: true FirstChar: 31 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-It35 Flags: Symbolic FontBBox: -1, -252, 780, 712 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTSYN40 FontSubset: true FirstChar: 27 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTSYN40 Flags: Symbolic FontBBox: 0, -954, 987, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MTMI41 FontSubset: true FirstChar: 27 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTMI41 Flags: Symbolic FontBBox: 0, -207, 727, 676 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MinionPro-Regular38 FontSubset: true FirstChar: 27 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular38 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTSYN38 FontSubset: true FirstChar: 26 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTSYN38 Flags: Symbolic FontBBox: 0, -954, 987, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MTMI40 FontSubset: true FirstChar: 25 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTMI40 Flags: Symbolic FontBBox: 0, -207, 727, 676 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MTSYN25 FontSubset: true FirstChar: 29 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTSYN25 Flags: Symbolic FontBBox: 0, -954, 987, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MinionPro-It19 FontSubset: true FirstChar: 31 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-It19 Flags: Symbolic FontBBox: -1, -252, 780, 712 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTMI21 FontSubset: true FirstChar: 30 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTMI21 Flags: Symbolic FontBBox: 0, -207, 727, 676 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: BRAMUQ+CMEX106 FontSubset: true FirstChar: 31 LastChar: 33 FontDescriptor: FontName: BRAMUQ+CMEX106 Flags: Symbolic FontBBox: 0, -2359, 1387, 40 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTSYN18 FontSubset: true FirstChar: 29 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTSYN18 Flags: Symbolic FontBBox: 0, -954, 987, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MTSYN17 FontSubset: true FirstChar: 30 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTSYN17 Flags: Symbolic FontBBox: 0, -954, 987, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MTMI25 FontSubset: true FirstChar: 24 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTMI25 Flags: Symbolic FontBBox: 0, -207, 727, 676 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MTMI20 FontSubset: true FirstChar: 30 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTMI20 Flags: Symbolic FontBBox: 0, -207, 727, 676 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: QQNYWM+TimesMath-LightScript8 FontSubset: true FirstChar: 28 LastChar: 33 FontDescriptor: FontName: QQNYWM+TimesMath-LightScript8 Flags: Symbolic, AllCap FontBBox: 0, -13, 968, 686 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: BRAMUQ+CMEX108 FontSubset: true FirstChar: 30 LastChar: 33 FontDescriptor: FontName: BRAMUQ+CMEX108 Flags: Symbolic FontBBox: 0, -2359, 1387, 40 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MinionPro-Regular19 FontSubset: true FirstChar: 30 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular19 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MinionPro-It15 FontSubset: true FirstChar: 29 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-It15 Flags: Symbolic FontBBox: -1, -252, 780, 712 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: BRAMUQ+CMEX109 FontSubset: true FirstChar: 28 LastChar: 33 FontDescriptor: FontName: BRAMUQ+CMEX109 Flags: Symbolic FontBBox: 0, -2359, 1387, 40 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MinionPro-Regular20 FontSubset: true FirstChar: 27 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular20 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTSYN26 FontSubset: true FirstChar: 25 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTSYN26 Flags: Symbolic FontBBox: 0, -954, 987, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MinionPro-It20 FontSubset: true FirstChar: 28 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-It20 Flags: Symbolic FontBBox: -1, -252, 780, 712 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTMI23 FontSubset: true FirstChar: 29 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTMI23 Flags: Symbolic FontBBox: 0, -207, 727, 676 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MTSYN24 FontSubset: true FirstChar: 28 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTSYN24 Flags: Symbolic FontBBox: 0, -954, 987, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MinionPro-Regular22 FontSubset: true FirstChar: 29 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular22 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: QQNYWM+TimesMath-LightScript7 FontSubset: true FirstChar: 30 LastChar: 33 FontDescriptor: FontName: QQNYWM+TimesMath-LightScript7 Flags: Symbolic, AllCap FontBBox: 0, -13, 968, 686 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MinionPro-It22 FontSubset: true FirstChar: 31 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-It22 Flags: Symbolic FontBBox: -1, -252, 780, 712 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MinionPro-It23 FontSubset: true FirstChar: 29 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-It23 Flags: Symbolic FontBBox: -1, -252, 780, 712 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MinionPro-It18 FontSubset: true FirstChar: 28 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-It18 Flags: Symbolic FontBBox: -1, -252, 780, 712 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MinionPro-Regular16 FontSubset: true FirstChar: 29 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular16 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: BRAMUQ+CMEX107 FontSubset: true FirstChar: 28 LastChar: 33 FontDescriptor: FontName: BRAMUQ+CMEX107 Flags: Symbolic FontBBox: 0, -2359, 1387, 40 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MinionPro-Regular18 FontSubset: true FirstChar: 29 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular18 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTMI22 FontSubset: true FirstChar: 23 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTMI22 Flags: Symbolic FontBBox: 0, -207, 727, 676 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MTMI24 FontSubset: true FirstChar: 27 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTMI24 Flags: Symbolic FontBBox: 0, -207, 727, 676 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MTSYN19 FontSubset: true FirstChar: 28 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTSYN19 Flags: Symbolic FontBBox: 0, -954, 987, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MTMI19 FontSubset: true FirstChar: 29 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTMI19 Flags: Symbolic FontBBox: 0, -207, 727, 676 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: BRAMUQ+CMEX1010 FontSubset: true FirstChar: 29 LastChar: 33 FontDescriptor: FontName: BRAMUQ+CMEX1010 Flags: Symbolic FontBBox: 0, -2359, 1387, 40 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTSYN22 FontSubset: true FirstChar: 28 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTSYN22 Flags: Symbolic FontBBox: 0, -954, 987, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MTSYN21 FontSubset: true FirstChar: 30 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTSYN21 Flags: Symbolic FontBBox: 0, -954, 987, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MinionPro-Regular17 FontSubset: true FirstChar: 28 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular17 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTSYN23 FontSubset: true FirstChar: 31 LastChar: 33 FontDescriptor: FontName: MNHJSU+MTSYN23 Flags: Symbolic FontBBox: 0, -954, 987, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MNHJSU+MinionPro-Regular21 FontSubset: true FirstChar: 29 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular21 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MinionPro-It21 FontSubset: true FirstChar: 30 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-It21 Flags: Symbolic FontBBox: -1, -252, 780, 712 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MinionPro-Regular15 FontSubset: true FirstChar: 29 LastChar: 33 FontDescriptor: FontName: MNHJSU+MinionPro-Regular15 Flags: Symbolic, AllCap FontBBox: 0, -117, 500, 700 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MNHJSU+MTSYN20 FontSubset: true FirstChar: 31 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Gallen J. Roberto Romero-Arias Aurora Hernandez-Machado Rafael A. Barrio 10.1038/s41598-021-88851-y 2010-04-23 true springer.com springerlink.com https://doi.org/10.1038/s41598-021-88851-y 10.1038/s41598-021-88851-y 2045-2322 journal Scientific Reports The Author(s) 2010-04-23 true 10.1038/s41598-021-88851-y noindex springer.com springerlink.com VoR uuid:e574de37-226f-4049-b741-2347432c1d89 uuid:0e181e6f-cd4d-4911-9999-539a9d7c564c default 1 converted uuid:ea191ded-e735-42b4-8b5b-a618bc369d3c converted to PDF/A-2b pdfToolbox 2021-04-29T12:44:55+05:30 converted uuid:266851b5-29b2-46c3-a4fc-8dff82fc8640 converted to PDF/A-2b pdfToolbox 2021-04-29T12:45:47+05:30 Adobe PDF Library 15.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) 2 B http://ns.adobe.com/pdfx/1.3/ pdfx Adobe Document Info PDF eXtension Schema external Mirrors crossmark:MajorVersionDate CrossmarkMajorVersionDate Text external Mirrors crossmark:CrossmarkDomainExclusive CrossmarkDomainExclusive Text internal Mirrors crossmark:DOI doi Text external Mirrors crossmark:CrosMarkDomains CrossMarkDomains seq Text internal A name object indicating whether the document has been modified to include trapping information robots Text internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text http://crossref.org/crossmark/1.0/ crossmark Crossmark Schema internal Usual same as prism:doi DOI Text external The date when a publication was publishe. MajorVersionDate Text internal CrossmarkDomainExclusive CrossmarkDomainExclusive Text internal CrossMarkDomains CrossMarkDomains seq Text http://prismstandard.org/namespaces/basic/2.0/ prism Prism Schema external This element provides the url for an article or unit of content. The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary. url URI external The Digital Object Identifier for the article. The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL). doi Text external ISSN for an electronic version of the issue in which the resource occurs. Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. 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Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.” publicationName Text external Copyright copyright Text http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. DocumentID URI internal The common identifier for all versions and renditions of a document. OriginalDocumentID URI internal A reference to the original document from which this one is derived. It is a minimal reference; missing components can be assumed to be unchanged. For example, a new version might only need to specify the instance ID and version number of the previous version, or a rendition might only need to specify the instance ID and rendition class of the original. DerivedFrom ResourceRef Identifies a portion of a document. This can be a position at which the document has been changed since the most recent event history (stEvt:changed). For a resource within an xmpMM:Ingredients list, the ResourceRef uses this type to identify both the portion of the containing document that refers to the resource, and the portion of the referenced resource that is referenced. http://ns.adobe.com/xap/1.0/sType/Part# stPart Part http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text http://ns.adobe.com/xap/1.0/t/pg/ xmpTPg XMP Paged-Text internal XMP08 Spec: An ordered array of plate names that are needed to print the document (including any in contained documents). 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