01219a2a9625fec27a1a9bf32ad7daba pmc_33959901.pdf a50cabf8098a5d06842dc51f0aa81bad41e3fe42 pmc_33959901.pdf a86b5f01476916da5bcf478c8c245d15482439ae5666f4d9b1a8b1d65b05687f pmc_33959901.pdf Title: Multidisciplinary practice guidelines for the diagnosis, genetic counseling and treatment of pheochromocytomas and paragangliomas Subject: Clinical and Translational Oncology, https://doi.org/10.1007/s12094-021-02622-9 Keywords: Pheochromocytoma,Paraganglioma,Diagnosis,Treatment,Genetic counseling,Multidisciplinary,Guidelines Author: R. Garcia-Carbonero Creator: Springer Producer: Acrobat Distiller 10.1.8 (Windows) CreationDate: Thu May 6 13:40:12 2021 CEST ModDate: Mon Aug 16 17:36:48 2021 CEST Tagged: no UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 25 Encrypted: no Page size: 595.276 x 790.866 pts Page rot: 0 File size: 2176257 bytes Optimized: yes PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- MyriadPro-SemiCn Type 1C WinAnsi yes no yes 952 0 MyriadPro-Semibold Type 1C Custom yes no yes 953 0 MyriadPro-SemiboldSemiCn Type 1C Custom yes no yes 954 0 MyriadPro-Bold Type 1C Custom yes no yes 965 0 ULUXFA+STIX-Regular Type 1C Custom yes yes yes 963 0 XXFNYR+Wingdings-Regular Type 1C WinAnsi yes yes yes 975 0 QBKFDY+MyriadPro-SemiCn2 Type 1C WinAnsi yes yes yes 1008 0 Springnew-Regular Type 1C WinAnsi yes no yes 1012 0 STIX-Italic Type 1C Custom yes no yes 380 0 MyriadPro-BoldSemiCn Type 1C Custom yes no yes 381 0 Springnew-Regular2 Type 1C WinAnsi yes no yes 390 0 Springnew-Regular3 Type 1C WinAnsi yes no yes 447 0 YNMBJS+TimesNewRomanPSMT CID TrueType Identity-H yes yes yes 477 0 YNMBJS+Code2000 CID TrueType Identity-H yes yes yes 531 0 RKSIAQ+STIX-Bold Type 1C WinAnsi yes yes yes 619 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-05-27 02:45:31 CEST RepresentationInformation: pmc_33959901.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-03-31 12:09:56 CEST Size: 2176257 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 1085 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Multidisciplinary practice guidelines for the diagnosis, genetic counseling and treatment of pheochromocytomas and paraganglio洀愀猩㸾൥湤潢樍㄰㌱‰扪഼㰯䐨ㄲ〹㑟㈰㈱弲㘲㉟䅲瑩捬攮楮摤㩁湣桯爠ㄺㄸ㤩⽓⽇潔漾㸍敮摯扪റ〳㈠〠潢樍㰼⽁‱〸㌠〠刯䍛〮〠〮〠〮そ⽃潵湴‰⽆‰⽎數琠㄰㔷‰⁒⽐慲敮琠㄰㌰‰⁒⽔楴汥⣾＀䄀戀猀琀爀愀挀琩㸾൥湤潢樍㄰㌳‰扪഼㰯䄠㄰㌴‰⁒⽃嬰⸰‰⸰‰⸰崯䍯畮琠〯䘠〯偡牥湴‱〳〠〠刯偲敶‱〳㔠〠刯呩瑬攨References Children: Item: Title: Abstract Item: Title: Introduction Item: Title: Epidemiology Item: Title: Anatomy, pathology and molecular pathways Children: Item: Title: Anatomy Item: Title: Histopathological features Item: Title: Stratification of risk and staging Item: Title: Molecular basis of PPGL Item: Title: Molecular classification of PPGL Item: Title: Clinical presentation Item: Title: Hereditary predisposition syndromes and genetic counseling and testing Item: Title: Diagnostic procedures Children: Item: Title: Biochemical testing Item: Title: Imaging studies Item: Title: Treatment Children: Item: Title: Therapeutic strategy Item: Title: Catecholamine blockade Item: Title: Surgery Item: Title: Radiotherapy and radiometabolic therapy Children: Item: Title: Radiotherapy Item: Title: Radiometabolic therapy Item: Title: Systemic therapy Item: Title: Local ablative therapy and supportive care Item: Title: Follow-up recommendations Item: Title: Acknowledgements Item: Title: References Info: Title: Multidisciplinary practice guidelines for the diagnosis, genetic counseling and treatment of pheochromocytomas and paragangliomas Author: R. Garcia-Carbonero Subject: Clinical and Translational Oncology, https://doi.org/10.1007/s12094-021-02622-9 Keywords: Pheochromocytoma,Paraganglioma,Diagnosis,Treatment,Genetic counseling,Multidisciplinary,Guidelines Creator: Springer Producer: Acrobat Distiller 10.1.8 (Windows) CreationDate: Thu May 06 14:10:12 CEST 2021 ModDate: Mon Aug 16 18:06:48 CEST 2021 ID: 0xdcee6efb91be544d816c109a044c8385, 0xe01b0a63108a3940854a2ccc7f6fdf10 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1500 ImageHeight: 1145 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1772 ImageHeight: 1238 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1772 ImageHeight: 983 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Name: X Fonts: Type0: Font: BaseFont: YNMBJS+Code2000 Encoding: Identity-H ToUnicode: true Font: BaseFont: YNMBJS+TimesNewRomanPSMT Encoding: Identity-H ToUnicode: true Type1: Font: BaseFont: ULUXFA+STIX-Regular FontSubset: true FirstChar: 22 LastChar: 252 FontDescriptor: FontName: ULUXFA+STIX-Regular Flags: Serif, Nonsymbolic FontBBox: -970, -486, 2208, 1023 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-Bold FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Bold Flags: Nonsymbolic FontBBox: -163, -250, 1256, 989 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-SemiCn FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-SemiCn Flags: Nonsymbolic FontBBox: -128, -250, 1059, 876 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: MyriadPro-Semibold FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Semibold Flags: Nonsymbolic FontBBox: -161, -250, 1198, 972 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-SemiboldSemiCn FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-SemiboldSemiCn Flags: Nonsymbolic FontBBox: -131, -250, 1115, 886 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: RKSIAQ+STIX-Bold FontSubset: true FirstChar: 0 LastChar: 255 FontDescriptor: FontName: RKSIAQ+STIX-Bold Flags: Serif, Nonsymbolic FontBBox: -998, -552, 2000, 1055 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: STIX-Italic FirstChar: 0 LastChar: 255 FontDescriptor: FontName: STIX-Italic Flags: Serif, Nonsymbolic, Italic FontBBox: -970, -305, 1429, 1023 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-BoldSemiCn FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-BoldSemiCn Flags: Nonsymbolic FontBBox: -133, -250, 1161, 894 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: XXFNYR+Wingdings-Regular FontSubset: true FirstChar: 0 LastChar: 255 FontDescriptor: FontName: XXFNYR+Wingdings-Regular Flags: Nonsymbolic FontBBox: 0, -103, 1359, 439 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true CIDFontType2: Font: BaseFont: YNMBJS+TimesNewRomanPSMT CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: YNMBJS+TimesNewRomanPSMT Flags: Serif, Symbolic FontBBox: -568, -307, 2046, 1040 FontFile2: true Font: BaseFont: YNMBJS+Code2000 CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: YNMBJS+Code2000 Flags: Serif, Symbolic FontBBox: -1111, -295, 2107, 977 FontFile2: true XMP: 2021-05-06T17:10:12+05:30 Springer 2021-08-16T21:06:48+05:30 2021-08-16T21:06:48+05:30 Acrobat Distiller 10.1.8 (Windows) Pheochromocytoma,Paraganglioma,Diagnosis,Treatment,Genetic counseling,Multidisciplinary,Guidelines application/pdf https://doi.org/10.1007/s12094-021-02622-9 Springer International Publishing Clinical and Translational Oncology, https://doi.org/10.1007/s12094-021-02622-9 Pheochromocytoma Paraganglioma Diagnosis Treatment Genetic counseling Multidisciplinary Guidelines Multidisciplinary practice guidelines for the diagnosis, genetic counseling and treatment of pheochromocytomas and paragangliomas R. Garcia-Carbonero F. Matute Teresa E. Mercader-Cidoncha M. Mitjavila-Casanovas M. Robledo I. Tena C. Alvarez-Escola M. Arístegui M. R. Bella-Cueto C. Ferrer-Albiach F. A. Hanzu 10.1007/s12094-021-02622-9 2010-04-23 true springer.com springerlink.com https://doi.org/10.1007/s12094-021-02622-9 10.1007/s12094-021-02622-9 1699-3055 23 10 1995 2019 journal Clinical and Translational Oncology The Author(s) 2010-04-23 true 10.1007/s12094-021-02622-9 noindex springer.com springerlink.com VoR uuid:72ef336d-ed0b-4a65-a833-2054971478d3 uuid:b6f72c0c-dc9f-4da1-971e-f701ecaaf4af default 1 converted uuid:3bc2897e-a3f3-4048-b109-b98f6a30ffb8 converted to PDF/A-2b pdfToolbox 2021-08-16T21:06:00+05:30 converted uuid:f39b9ede-3eb2-473a-b71b-4543b05fb100 converted to PDF/A-2b pdfToolbox 2021-08-16T21:06:47+05:30 2 B R. Garcia-Carbonero https://orcid.org/0000-0002-3342-397X F. Matute Teresa https://orcid.org/0000-0001-8691-5997 E. Mercader-Cidoncha https://orcid.org/0000-0002-1836-0165 M. 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Annotation: Subtype: Link Rect: 134, 411, 144, 396 Flags: Print AppearanceDictionary: true Destination: 328 Annotation: Subtype: Link Rect: 54, 336, 64, 321 Flags: Print AppearanceDictionary: true Destination: 328 Annotation: Subtype: Link Rect: 69, 336, 79, 321 Flags: Print AppearanceDictionary: true Destination: 328 Annotation: Subtype: Link Rect: 187, 261, 197, 246 Flags: Print AppearanceDictionary: true Destination: 318 Annotation: Subtype: Link Rect: 202, 261, 212, 246 Flags: Print AppearanceDictionary: true Destination: 328 Annotation: Subtype: Link Rect: 252, 236, 262, 221 Flags: Print AppearanceDictionary: true Destination: 318 Annotation: Subtype: Link Rect: 267, 236, 278, 221 Flags: Print AppearanceDictionary: true Destination: 328 Annotation: Subtype: Link Rect: 54, 161, 64, 146 Flags: Print AppearanceDictionary: true Destination: 318 Annotation: Subtype: Link Rect: 69, 161, 79, 146 Flags: Print AppearanceDictionary: true Destination: 328 Annotation: Subtype: Link Rect: 276, 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AppearanceDictionary: true Destination: 325 Annotation: Subtype: Link Rect: 528, 424, 538, 409 Flags: Print AppearanceDictionary: true Destination: 325 Annotation: Subtype: Link Rect: 486, 324, 496, 309 Flags: Print AppearanceDictionary: true Destination: 328 Annotation: Subtype: Link Rect: 309, 286, 319, 271 Flags: Print AppearanceDictionary: true Destination: 328 Annotation: Subtype: Link Rect: 357, 224, 362, 209 Flags: Print AppearanceDictionary: true Destination: 203 Annotation: Subtype: Link Rect: 438, 174, 448, 159 Flags: Print AppearanceDictionary: true Destination: 328 Annotation: Subtype: Link Rect: 453, 174, 463, 159 Flags: Print AppearanceDictionary: true Destination: 328 Thumb: true Page: Label: 2008 Sequence: 14 Annotations: Annotation: Subtype: Link Rect: 161, 261, 171, 246 Flags: Print AppearanceDictionary: true Destination: 328 Annotation: Subtype: Link Rect: 199, 261, 204, 246 Flags: Print AppearanceDictionary: true Destination: 203 Annotation: Subtype: Link Rect: 54, 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