897646891a618921c533e4555c56ba7d 255576.pdf 27caeac30e8a4b90ea424e998ce2a2cb4e5586ea 255576.pdf 1c029ad85af9f2a4d0e31312deecc9cbeae1f797e3eaf6b74eaf662427f77c8b 255576.pdf Title: Dead space estimates may not be independently associated with 28-day mortality in COVID-19 ARDS Subject: Critical Care, https://doi.org/10.1186/s13054-021-03570-0 Keywords: Acute respiratory distress syndrome;ARDS;Respiratory dead space;Dead space;Ventilatory ratio;COVID-19;Mortality;Prognostication Author: Luis Morales-Quinteros Creator: Adobe InDesign 15.0 (Windows) Producer: Adobe PDF Library 15.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Thu May 13 12:51:11 2021 CEST ModDate: Mon May 17 14:55:18 2021 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 13 Encrypted: no Page size: 595.276 x 790.866 pts Page rot: 0 File size: 2114914 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID 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RepresentationInformation: 255576.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-06-02 09:44:05 CEST Size: 2114914 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 468 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en-US Outlines: Item: Title: Dead space estimates may not be independently associated with 28-day mortality in COVID-19 ARDS Children: Item: Title: Abstract Children: Item: Title: Background: Item: Title: Methods: Item: Title: Results: Item: Title: Conclusions: Item: Title: Background Item: Title: Methods Children: Item: Title: Study design and oversight Item: Title: Patients Item: Title: Data collection Item: Title: Data definition and exposure Item: Title: Outcomes Item: Title: Statistical analysis Item: Title: Results Children: Item: Title: Study population Item: Title: Markers of impaired ventilation Item: Title: Predictive accuracy of markers of impaired ventilation Item: Title: Sensitivity analysis Item: Title: Post-hoc analysis Item: Title: Discussion Item: Title: Conclusions Item: Title: Acknowledgements Item: Title: References Info: Title: Dead space estimates may not be independently associated with 28-day mortality in COVID-19 ARDS Author: Luis Morales-Quinteros Subject: Critical Care, https://doi.org/10.1186/s13054-021-03570-0 Keywords: Acute respiratory distress syndrome;ARDS;Respiratory dead space;Dead space;Ventilatory ratio;COVID-19;Mortality;Prognostication Creator: Adobe InDesign 15.0 (Windows) Producer: Adobe PDF Library 15.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) 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iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) Acute respiratory distress syndrome;ARDS;Respiratory dead space;Dead space;Ventilatory ratio;COVID-19;Mortality;Prognostication False application/pdf https://doi.org/10.1186/s13054-021-03570-0 BioMed Central Critical Care, https://doi.org/10.1186/s13054-021-03570-0 Acute respiratory distress syndrome ARDS Respiratory dead space Dead space Ventilatory ratio COVID-19 Mortality Prognostication Dead space estimates may not be independently associated with 28-day mortality in COVID-19 ARDS Luis Morales-Quinteros Ary Serpa Neto Antonio Artigas Lluis Blanch Michela Botta David A. Kaufman Marcus J. Schultz Anissa Tsonas Frederique Paulus Lieuwe D. Bos A. G. Algera L. S. Boers L. D. J. Bos M. Botta J. Pillay D. A. Dongelmans M. W. Hollmann J. Horn F. Paulus A. Serpa Neto M. J. Schultz A. M. Tsonas A. P. Vlaar M. Botta A. M. Tsonas J. P. van Akkeren A. G. Algera C. K. Algoe R. B. van Amstel Artigas A O. L. Baur P. van de Berg A. E. van den Berg D. C. J. J. Bergmans D. I. van den Bersselaar F. A. Bertens A. J. G. H. Bindels M. M. de Boer S.den Boer L. S. Boers M. Bogerd L. D. J. Bos M. Botta J. S. Breel H. de Bruin S. de Bruin C. L. Bruna L. A. Buiteman–Kruizinga O. Cremer R. M. Determann W. Dieperink D. A. Dongelmans H. S. Franke M. S. Galek–Aldridge M. J. de Graaff L. A. Hagens J. J. Haringman S. T. van der Heide P. L. J. van der Heiden N. F. L. Heijnen S. J. P. Hiel L. L. Hoeijmakers L. Hol M. W. Hollmann M. E. Hoogendoorn J. Horn R. van der Horst E. L. K. Ie D. Ivanov N. P. Juffermans E. Kho E. S. de Klerk A. W. M. M. Koopman-van Gemert M. Koopmans S. Kucukcelebi M. A. Kuiper D. W. de Lange N. van Mourik Morales-Quinteros L S. G. Nijbroek M. Onrust E. A. N. Oostdijk F. Paulus C. J. Pennartz J. Pillay L. Pisani I. M. Purmer T. C. D. Rettig J. P. Roozeman M. T. U. Schuijt M. J. Schultz A. Serpa Neto M. E. Sleeswijk M. R. Smit P. E. Spronk W. Stilma A. C. Strang A. M. Tsonas P. R. Tuinman C. M. A. Valk F. L. Veen-Schra L. I. Veldhuis P. van Velzen W. H. van der Ven A. P. J. Vlaar P. van Vliet P. H. J. van der Voort L. van Welie H. J. F. T. Wesselink H. H. van der Wier-Lubbers B. van Wijk T. Winters W. Y. Wong A. R. H. van Zanten 10.1186/s13054-021-03570-0 2010-04-23 true springer.com springerlink.com https://doi.org/10.1186/s13054-021-03570-0 10.1186/s13054-021-03570-0 1364-8535 journal Critical Care The Author(s) 2010-04-23 true 10.1186/s13054-021-03570-0 noindex springer.com springerlink.com uuid:a55f3b7d-9e9f-4420-a113-a2d00d2c4200 uuid:208cee14-9b72-4b69-849b-9b5863725a50 default 1 converted uuid:a55f3b7d-9e9f-4420-a113-a2d00d2c4200 converted to PDF/A-2b pdfToolbox 2021-05-14T02:07:18Z 2 B Luis Morales-Quinteros http://orcid.org/0000-0002-8937-9824 http://ns.adobe.com/pdfx/1.3/ pdfx Adobe Document Info PDF eXtension Schema external Mirrors crossmark:MajorVersionDate CrossmarkMajorVersionDate Text external Mirrors crossmark:CrossmarkDomainExclusive CrossmarkDomainExclusive Text internal Mirrors crossmark:DOI doi Text external Mirrors crossmark:CrosMarkDomains CrossMarkDomains seq Text internal A name object indicating whether the document has been modified to include trapping information robots Text internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text http://crossref.org/crossmark/1.0/ crossmark Crossmark Schema internal Usual same as prism:doi DOI Text external The date when a publication was publishe. 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If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL). doi Text external ISSN for an electronic version of the issue in which the resource occurs. Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. 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