5625c8b67fdbdb4454697fdae527415c pmc_34054748.pdf 8736614874bc89c1e0f60b73edc0a220e032acdf pmc_34054748.pdf 73f435ecb9a6c6f0cc10a1466a6fa904bda9810a499aec0c42e043367d89cfd0 pmc_34054748.pdf Title: Identifying the Specific Root Microbiome of the Hyperaccumulator Noccaea brachypetala Growing in Non-metalliferous Soils Subject: Noccaea brachypetala is a close relative of Noccaea caerulescens, a model plant species used in metal hyperaccumulation studies. Keywords: high-throughput sequencing (deep sequencing), Noccaea brachypetala, root-associated microbial communities, Zn/Cd hyperaccumulator, non-metalliferous soil Author: Soledad Martos Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.15 CreationDate: Mon May 10 11:52:23 2021 CEST ModDate: Mon May 10 11:52:23 2021 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 17 Encrypted: no Page size: 595.276 x 779.528 pts Page rot: 0 File size: 5738309 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- CKKWEL+MinionPro-Regular Type 1 Custom yes yes no 25 0 NAHTVU+HelveticaNeueLTStd-Bd Type 1 Custom yes yes no 26 0 JRAOLZ+HelveticaNeueLTStd-Lt Type 1 Custom yes yes no 27 0 DCVNAX+HelveticaNeueLTStd-BdIt Type 1 Custom yes yes no 32 0 WGBVKU+HelveticaNeueLTStd-LtIt Type 1 Custom yes yes no 33 0 LMWMOE+HelveticaNeueLTStd-MdIt Type 1 Custom yes yes no 34 0 ZQSYVF+MinionPro-It Type 1 Custom yes yes no 108 0 SYNAEY+MinionPro-Bold Type 1 Custom yes yes no 198 0 XLOTAJ+MTSYN Type 1 Builtin yes yes no 202 0 CJXQJX+MTGU Type 1 Builtin yes yes no 317 0 XODHDR+RBLMI Type 1 Builtin yes yes no 324 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-05-27 02:45:15 CEST RepresentationInformation: pmc_34054748.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-03-31 12:13:56 CEST Size: 5738309 Format: PDF Version: 1.5 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 987 FreeObjects: 6 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Identifying the Specific Root Microbiome of the Hyperaccumulator Noccaea brachypetala Growing in Non-metalliferous Soils Children: Item: Title: Introduction Item: Title: Materials and Methods Children: Item: Title: Plant and Soil Sampling Item: Title: Analysis of Metal Content From Soil and Plant Samples Item: Title: Sampling of Rhizosphere and Rhizoplane Compartments Item: Title: Library Generation and Sequencing of Bacterial and Fungal DNA Regions Item: Title: Quality Control of Sequencing Data Item: Title: Diversity Metrics and Relative Abundance Item: Title: Co-occurrence Network Item: Title: Differential Abundance Analysis Item: Title: Metabolic and Functional Analysis Item: Title: Results Children: Item: Title: Soil and Leaf Mineral Content Item: Title: Root Compartment and Plant Species Condition the Microbial Composition Item: Title: High Influence of Root Compartment and Plant Species in the Bacterial Community Item: Title: More Complex Network in the Rhizoplane of N. brachypetala Item: Title: Higher Relative Abundance of Bacteria and Fungi in N. brachypetala With Some Exclusive Taxa Item: Title: The Bacterial Community of N. brachypetala Is Globally More Diverse With Higher Relative Abundance in the Rhizoplane Compartment Item: Title: The Fungal Community of N. brachypetala Presents a Reduced Differential Abundance Compared to the Non-hyperaccumulator Species Item: Title: Discussion Item: Title: Data Availability Statement Item: Title: Author Contributions Item: Title: Funding Item: Title: Acknowledgments Item: Title: Supplementary Material Item: Title: References Info: Title: Identifying the Specific Root Microbiome of the Hyperaccumulator Noccaea brachypetala Growing in Non-metalliferous Soils Author: Soledad Martos Subject: Noccaea brachypetala is a close relative of Noccaea caerulescens, a model plant species used in metal hyperaccumulation studies. Keywords: high-throughput sequencing (deep sequencing), Noccaea brachypetala, root-associated microbial communities, Zn/Cd hyperaccumulator, non-metalliferous soil Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.15 CreationDate: Mon May 10 12:22:23 CEST 2021 ModDate: Mon May 10 12:22:23 CEST 2021 ID: 0x67b22ab61675263ad4f1f15ea2821f58, 0x67b22ab61675263ad4f1f15ea2821f58 Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: DCVNAX+HelveticaNeueLTStd-BdIt FontSubset: true FirstChar: 42 LastChar: 121 FontDescriptor: FontName: DCVNAX+HelveticaNeueLTStd-BdIt Flags: Symbolic FontBBox: -166, -218, 1129, 975 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: WGBVKU+HelveticaNeueLTStd-LtIt FontSubset: true FirstChar: 2 LastChar: 242 FontDescriptor: FontName: WGBVKU+HelveticaNeueLTStd-LtIt Flags: Symbolic FontBBox: -165, -214, 1099, 951 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: LMWMOE+HelveticaNeueLTStd-MdIt FontSubset: true FirstChar: 42 LastChar: 237 FontDescriptor: FontName: LMWMOE+HelveticaNeueLTStd-MdIt Flags: Symbolic FontBBox: -165, -218, 1125, 947 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: XODHDR+RBLMI FontSubset: true FirstChar: 60 LastChar: 62 FontDescriptor: FontName: XODHDR+RBLMI Flags: Symbolic FontBBox: -11, -230, 987, 750 FontFile: true Font: BaseFont: SYNAEY+MinionPro-Bold FontSubset: true FirstChar: 3 LastChar: 150 FontDescriptor: FontName: SYNAEY+MinionPro-Bold Flags: Symbolic FontBBox: -318, -360, 1684, 917 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: CKKWEL+MinionPro-Regular FontSubset: true FirstChar: 2 LastChar: 252 FontDescriptor: FontName: CKKWEL+MinionPro-Regular Flags: Symbolic FontBBox: -289, -360, 1684, 917 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: NAHTVU+HelveticaNeueLTStd-Bd FontSubset: true FirstChar: 2 LastChar: 124 FontDescriptor: FontName: NAHTVU+HelveticaNeueLTStd-Bd Flags: Symbolic FontBBox: -166, -218, 1078, 975 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: XLOTAJ+MTSYN FontSubset: true FirstChar: 0 LastChar: 48 FontDescriptor: FontName: XLOTAJ+MTSYN Flags: Symbolic FontBBox: 0, -954, 1043, 900 FontFile: true Font: BaseFont: JRAOLZ+HelveticaNeueLTStd-Lt FontSubset: true FirstChar: 2 LastChar: 250 FontDescriptor: FontName: JRAOLZ+HelveticaNeueLTStd-Lt Flags: Symbolic FontBBox: -166, -214, 1050, 967 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: ZQSYVF+MinionPro-It FontSubset: true FirstChar: 2 LastChar: 237 FontDescriptor: FontName: ZQSYVF+MinionPro-It Flags: Symbolic FontBBox: -201, -360, 1684, 919 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: CJXQJX+MTGU FontSubset: true FirstChar: 97 LastChar: 108 FontDescriptor: FontName: CJXQJX+MTGU Flags: Symbolic FontBBox: 25, -213, 839, 683 FontFile: true XMP: high-throughput sequencing (deep sequencing), Noccaea brachypetala, root-associated microbial communities, Zn/Cd hyperaccumulator, non-metalliferous soil pdfTeX-1.40.15 1.5 application/pdf Identifying the Specific Root Microbiome of the Hyperaccumulator Noccaea brachypetala Growing in Non-metalliferous Soils Noccaea brachypetala is a close relative of Noccaea caerulescens, a model plant species used in metal hyperaccumulation studies. Soledad Martos high-throughput sequencing (deep sequencing) Noccaea brachypetala root-associated microbial communities Zn/Cd hyperaccumulator non-metalliferous soil 2021-05-10T15:22:23+05:30 fmicb-12-639997.tex 2021-05-10T15:22:23+05:30 2021-05-10T15:22:23+05:30 2021-05-10T15:22:23+05:30 LaTeX with hyperref package uuid:18dcef7a-ea39-4b62-b67a-ef20059bbbbb uuid:0a82b620-a333-43e4-9d18-8820a3e467f7 Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 43, 718, 160, 754 Annotation: Subtype: Link Rect: 474, 736, 551, 745 Annotation: Subtype: Link Rect: 476, 727, 551, 737 Annotation: Subtype: Link Rect: 449, 718, 551, 729 Annotation: Subtype: Link Rect: 86, 462, 160, 472 Annotation: Subtype: Link Rect: 71, 67, 160, 74 Annotation: Subtype: Link Rect: 521, 677, 551, 707 Annotation: Subtype: Link Rect: 176, 515, 551, 605 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 432, 29, 551, 38 Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 188, 273, 262, 285 ActionDest: 798 Annotation: Subtype: Link Rect: 267, 273, 287, 285 ActionDest: 798 Annotation: Subtype: Link Rect: 232, 239, 263, 250 ActionDest: 753 Annotation: Subtype: Link Rect: 267, 239, 287, 250 ActionDest: 753 Annotation: Subtype: Link Rect: 115, 204, 177, 216 ActionDest: 753 Annotation: Subtype: Link Rect: 182, 204, 202, 216 ActionDest: 753 Annotation: Subtype: Link Rect: 217, 193, 263, 204 ActionDest: 753 Annotation: Subtype: Link Rect: 267, 193, 287, 204 ActionDest: 753 Annotation: Subtype: Link Rect: 128, 182, 177, 193 ActionDest: 690 Annotation: Subtype: Link Rect: 180, 182, 200, 193 ActionDest: 690 Annotation: Subtype: Link Rect: 47, 170, 104, 181 ActionDest: 798 Annotation: Subtype: Link Rect: 110, 170, 130, 181 ActionDest: 798 Annotation: Subtype: Link Rect: 216, 170, 290, 181 ActionDest: 798 Annotation: Subtype: Link Rect: 43, 159, 64, 170 ActionDest: 798 Annotation: Subtype: Link Rect: 162, 159, 216, 170 ActionDest: 798 Annotation: Subtype: Link Rect: 219, 159, 239, 170 ActionDest: 798 Annotation: Subtype: Link Rect: 143, 113, 200, 124 ActionDest: 753 Annotation: Subtype: Link Rect: 204, 113, 224, 124 ActionDest: 753 Annotation: Subtype: Link Rect: 449, 377, 526, 388 ActionDest: 798 Annotation: Subtype: Link Rect: 528, 377, 549, 388 ActionDest: 798 Annotation: Subtype: Link Rect: 302, 365, 393, 376 ActionDest: 753 Annotation: Subtype: Link Rect: 395, 365, 415, 376 ActionDest: 753 Annotation: Subtype: Link Rect: 498, 296, 549, 307 ActionDest: 798 Annotation: Subtype: Link Rect: 302, 285, 327, 296 ActionDest: 798 Annotation: Subtype: Link Rect: 500, 273, 549, 285 ActionDest: 798 Annotation: Subtype: Link Rect: 302, 263, 322, 273 ActionDest: 798 Annotation: Subtype: Link Rect: 354, 239, 417, 250 ActionDest: 753 Annotation: Subtype: Link Rect: 425, 239, 445, 250 ActionDest: 753 Annotation: Subtype: Link Rect: 398, 216, 457, 227 ActionDest: 798 Annotation: Subtype: Link Rect: 461, 216, 482, 227 ActionDest: 798 Annotation: Subtype: Link Rect: 468, 204, 549, 216 ActionDest: 798 Annotation: Subtype: Link Rect: 302, 193, 322, 204 ActionDest: 798 Annotation: Subtype: Link Rect: 453, 159, 521, 170 ActionDest: 690 Annotation: Subtype: Link Rect: 528, 159, 549, 170 ActionDest: 690 Annotation: Subtype: Link Rect: 302, 147, 354, 158 ActionDest: 798 Annotation: Subtype: Link Rect: 359, 147, 379, 158 ActionDest: 798 Annotation: Subtype: Link Rect: 384, 147, 409, 158 ActionDest: 798 Annotation: Subtype: Link Rect: 372, 113, 438, 124 ActionDest: 798 Annotation: Subtype: Link Rect: 443, 113, 463, 124 ActionDest: 798 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 432, 29, 551, 38 Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 0, 340, 1, 352 ActionDest: 5 Annotation: Subtype: Link Rect: 0, 340, 1, 352 ActionDest: 5 Annotation: Subtype: Link Rect: 47, 249, 94, 259 ActionDest: 690 Annotation: Subtype: Link Rect: 96, 249, 116, 259 ActionDest: 690 Annotation: Subtype: Link Rect: 123, 248, 165, 259 ActionDest: 753 Annotation: Subtype: Link Rect: 171, 248, 191, 259 ActionDest: 753 Annotation: Subtype: Link Rect: 197, 248, 260, 259 ActionDest: 798 Annotation: Subtype: Link Rect: 267, 248, 287, 259 ActionDest: 798 Annotation: Subtype: Link Rect: 190, 225, 238, 236 ActionDest: 753 Annotation: Subtype: Link Rect: 246, 225, 266, 236 ActionDest: 753 Annotation: Subtype: Link Rect: 47, 202, 107, 213 ActionDest: 798 Annotation: Subtype: Link Rect: 113, 202, 134, 213 ActionDest: 798 Annotation: Subtype: Link Rect: 75, 133, 136, 144 ActionDest: 753 Annotation: Subtype: Link Rect: 140, 133, 160, 144 ActionDest: 753 Annotation: Subtype: Link Rect: 164, 133, 226, 144 ActionDest: 753 Annotation: Subtype: Link Rect: 229, 133, 250, 144 ActionDest: 753 Annotation: Subtype: Link Rect: 253, 133, 292, 144 ActionDest: 798 Annotation: Subtype: Link Rect: 43, 122, 63, 133 ActionDest: 798 Annotation: Subtype: Link Rect: 66, 122, 86, 133 ActionDest: 798 Annotation: Subtype: Link Rect: 88, 122, 139, 133 ActionDest: 753 Annotation: Subtype: Link Rect: 141, 122, 161, 133 ActionDest: 753 Annotation: Subtype: Link Rect: 141, 99, 186, 110 ActionDest: 753 Annotation: Subtype: Link Rect: 188, 99, 208, 110 ActionDest: 753 Annotation: Subtype: Link Rect: 210, 99, 239, 110 ActionDest: 753 Annotation: Subtype: Link Rect: 241, 99, 261, 110 ActionDest: 753 Annotation: Subtype: Link Rect: 159, 87, 210, 99 ActionDest: 753 Annotation: Subtype: Link Rect: 212, 87, 232, 99 ActionDest: 753 Annotation: Subtype: Link Rect: 235, 87, 292, 99 ActionDest: 753 Annotation: Subtype: Link Rect: 43, 76, 64, 87 ActionDest: 753 Annotation: Subtype: Link Rect: 67, 76, 88, 87 ActionDest: 753 Annotation: Subtype: Link Rect: 305, 706, 381, 717 ActionDest: 798 Annotation: Subtype: Link Rect: 384, 706, 404, 717 ActionDest: 798 Annotation: Subtype: Link Rect: 407, 706, 486, 717 ActionDest: 753 Annotation: Subtype: Link Rect: 490, 706, 510, 717 ActionDest: 753 Annotation: Subtype: Link Rect: 513, 706, 551, 717 ActionDest: 798 Annotation: Subtype: Link Rect: 302, 695, 324, 706 ActionDest: 798 Annotation: Subtype: Link Rect: 329, 695, 349, 706 ActionDest: 798 Annotation: Subtype: Link Rect: 305, 671, 375, 683 ActionDest: 753 Annotation: Subtype: Link Rect: 382, 671, 402, 683 ActionDest: 753 Annotation: Subtype: Link Rect: 410, 671, 474, 683 ActionDest: 798 Annotation: Subtype: Link Rect: 482, 671, 502, 683 ActionDest: 798 Annotation: Subtype: Link Rect: 450, 627, 493, 637 ActionDest: 753 Annotation: Subtype: Link Rect: 499, 627, 519, 637 ActionDest: 753 Annotation: Subtype: Link Rect: 524, 627, 551, 637 ActionDest: 798 Annotation: Subtype: Link Rect: 302, 614, 324, 626 ActionDest: 798 Annotation: Subtype: Link Rect: 328, 614, 352, 626 ActionDest: 798 Annotation: Subtype: Link Rect: 389, 387, 431, 399 ActionDest: 101 Annotation: Subtype: Link Rect: 477, 342, 507, 353 ActionDest: 251 Annotation: Subtype: Link Rect: 424, 319, 477, 330 ActionDest: 798 Annotation: Subtype: Link Rect: 481, 319, 501, 330 ActionDest: 798 Annotation: Subtype: Link Rect: 437, 285, 469, 296 ActionDest: 251 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 432, 29, 551, 38 Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 85, 308, 128, 320 ActionDest: 753 Annotation: Subtype: Link Rect: 131, 308, 151, 320 ActionDest: 753 Annotation: Subtype: Link Rect: 47, 122, 90, 133 ActionDest: 101 Annotation: Subtype: Link Rect: 43, 99, 99, 110 ActionDest: 753 Annotation: Subtype: Link Rect: 105, 99, 125, 110 ActionDest: 753 Annotation: Subtype: Link Rect: 150, 99, 210, 110 ActionDest: 753 Annotation: Subtype: Link Rect: 216, 99, 236, 110 ActionDest: 753 Annotation: Subtype: Link Rect: 512, 167, 551, 179 ActionDest: 753 Annotation: Subtype: Link Rect: 302, 156, 325, 167 ActionDest: 753 Annotation: Subtype: Link Rect: 330, 156, 350, 167 ActionDest: 753 Annotation: Subtype: Link Rect: 341, 99, 402, 110 ActionDest: 798 Annotation: Subtype: Link Rect: 408, 99, 428, 110 ActionDest: 798 Annotation: Subtype: Link Rect: 372, 64, 473, 76 ActionDest: 690 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 432, 29, 551, 38 Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 47, 683, 147, 694 ActionDest: 690 Annotation: Subtype: Link Rect: 137, 649, 241, 660 ActionDest: 690 Annotation: Subtype: Link Rect: 237, 569, 290, 580 ActionDest: 798 Annotation: Subtype: Link Rect: 43, 557, 64, 568 ActionDest: 798 Annotation: Subtype: Link Rect: 208, 557, 264, 568 ActionDest: 753 Annotation: Subtype: Link Rect: 267, 557, 287, 568 ActionDest: 753 Annotation: Subtype: Link Rect: 47, 523, 107, 534 ActionDest: 753 Annotation: Subtype: Link Rect: 111, 523, 131, 534 ActionDest: 753 Annotation: Subtype: Link Rect: 176, 500, 222, 511 ActionDest: 798 Annotation: Subtype: Link Rect: 225, 500, 246, 511 ActionDest: 798 Annotation: Subtype: Link Rect: 249, 412, 292, 424 ActionDest: 753 Annotation: Subtype: Link Rect: 43, 401, 94, 412 ActionDest: 753 Annotation: Subtype: Link Rect: 98, 401, 119, 412 ActionDest: 753 Annotation: Subtype: Link Rect: 81, 286, 139, 298 ActionDest: 798 Annotation: Subtype: Link Rect: 143, 286, 163, 298 ActionDest: 798 Annotation: Subtype: Link Rect: 470, 499, 525, 510 ActionDest: 798 Annotation: Subtype: Link Rect: 528, 499, 549, 510 ActionDest: 798 Annotation: Subtype: Link Rect: 302, 488, 347, 499 ActionDest: 798 Annotation: Subtype: Link Rect: 349, 488, 370, 499 ActionDest: 798 Annotation: Subtype: Link Rect: 372, 488, 438, 499 ActionDest: 753 Annotation: Subtype: Link Rect: 441, 488, 461, 499 ActionDest: 753 Annotation: Subtype: Link Rect: 468, 395, 520, 407 ActionDest: 753 Annotation: Subtype: Link Rect: 525, 395, 545, 407 ActionDest: 753 Annotation: Subtype: Link Rect: 305, 361, 357, 372 ActionDest: 798 Annotation: Subtype: Link Rect: 360, 361, 380, 372 ActionDest: 798 Annotation: Subtype: Link Rect: 490, 236, 533, 247 ActionDest: 350 Annotation: Subtype: Link Rect: 302, 225, 404, 236 ActionDest: 690 Annotation: Subtype: Link Rect: 338, 179, 381, 190 ActionDest: 350 Annotation: Subtype: Link Rect: 384, 144, 425, 156 ActionDest: 350 Annotation: Subtype: Link Rect: 305, 110, 347, 121 ActionDest: 350 Annotation: Subtype: Link Rect: 365, 110, 467, 121 ActionDest: 690 Annotation: Subtype: Link Rect: 354, 64, 456, 76 ActionDest: 690 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 432, 29, 551, 38 Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 164, 76, 206, 88 ActionDest: 350 Annotation: Subtype: Link Rect: 459, 127, 499, 138 ActionDest: 350 Annotation: Subtype: Link Rect: 378, 77, 499, 88 ActionDest: 690 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 432, 29, 551, 38 Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 132, 168, 190, 179 ActionDest: 385 Annotation: Subtype: Link Rect: 101, 133, 164, 144 ActionDest: 385 Annotation: Subtype: Link Rect: 162, 99, 218, 110 ActionDest: 385 Annotation: Subtype: Link Rect: 228, 64, 287, 76 ActionDest: 385 Annotation: Subtype: Link Rect: 477, 249, 517, 261 ActionDest: 385 Annotation: Subtype: Link Rect: 506, 238, 545, 249 ActionDest: 385 Annotation: Subtype: Link Rect: 305, 144, 363, 156 ActionDest: 414 Annotation: Subtype: Link Rect: 451, 122, 492, 133 ActionDest: 414 Annotation: Subtype: Link Rect: 305, 87, 361, 99 ActionDest: 414 Annotation: Subtype: Link Rect: 396, 64, 453, 76 ActionDest: 414 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 432, 29, 551, 38 Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 432, 29, 551, 38 Page: Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 120, 66, 176, 77 ActionDest: 414 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 432, 29, 551, 38 Page: Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 143, 76, 182, 88 ActionDest: 440 Annotation: Subtype: Link Rect: 182, 65, 290, 76 ActionDest: 690 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 432, 29, 551, 38 Page: Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 166, 706, 222, 717 ActionDest: 440 Annotation: Subtype: Link Rect: 47, 626, 90, 637 ActionDest: 440 Annotation: Subtype: Link Rect: 195, 591, 238, 603 ActionDest: 440 Annotation: Subtype: Link Rect: 231, 454, 287, 465 ActionDest: 440 Annotation: Subtype: Link Rect: 180, 431, 227, 442 ActionDest: 440 Annotation: Subtype: Link Rect: 230, 420, 292, 431 ActionDest: 690 Annotation: Subtype: Link Rect: 43, 408, 83, 419 ActionDest: 690 Annotation: Subtype: Link Rect: 97, 374, 140, 385 ActionDest: 440 Annotation: Subtype: Link Rect: 47, 213, 144, 225 ActionDest: 690 Annotation: Subtype: Link Rect: 207, 110, 244, 121 ActionDest: 467 Annotation: Subtype: Link Rect: 499, 706, 545, 717 ActionDest: 467 Annotation: Subtype: Link Rect: 414, 603, 524, 614 ActionDest: 690 Annotation: Subtype: Link Rect: 305, 523, 407, 534 ActionDest: 690 Annotation: Subtype: Link Rect: 405, 500, 459, 511 ActionDest: 467 Annotation: Subtype: Link Rect: 360, 465, 401, 477 ActionDest: 467 Annotation: Subtype: Link Rect: 305, 408, 349, 419 ActionDest: 467 Annotation: Subtype: Link Rect: 302, 385, 346, 396 ActionDest: 467 Annotation: Subtype: Link Rect: 419, 213, 479, 225 ActionDest: 541 Annotation: Subtype: Link Rect: 337, 168, 438, 179 ActionDest: 690 Annotation: Subtype: Link Rect: 436, 144, 545, 156 ActionDest: 690 Annotation: Subtype: Link Rect: 350, 110, 404, 121 ActionDest: 798 Annotation: Subtype: Link Rect: 408, 110, 428, 121 ActionDest: 798 Annotation: Subtype: Link Rect: 326, 99, 369, 110 ActionDest: 541 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 432, 29, 551, 38 Page: Sequence: 12 Annotations: Annotation: Subtype: Link Rect: 128, 198, 178, 209 ActionDest: 798 Annotation: Subtype: Link Rect: 182, 198, 207, 209 ActionDest: 798 Annotation: Subtype: Link Rect: 209, 140, 260, 152 ActionDest: 798 Annotation: Subtype: Link Rect: 267, 140, 287, 152 ActionDest: 798 Annotation: Subtype: Link Rect: 349, 129, 403, 140 ActionDest: 753 Annotation: Subtype: Link Rect: 408, 129, 428, 140 ActionDest: 753 Annotation: Subtype: Link Rect: 433, 129, 496, 140 ActionDest: 753 Annotation: Subtype: Link Rect: 501, 129, 521, 140 ActionDest: 753 Annotation: Subtype: Link Rect: 526, 129, 551, 140 ActionDest: 824 Annotation: Subtype: Link Rect: 302, 117, 325, 129 ActionDest: 824 Annotation: Subtype: Link Rect: 330, 117, 350, 129 ActionDest: 824 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 432, 29, 551, 38 Page: Sequence: 13 Annotations: Annotation: Subtype: Link Rect: 191, 694, 243, 706 ActionDest: 798 Annotation: Subtype: Link Rect: 248, 694, 268, 706 ActionDest: 798 Annotation: Subtype: Link Rect: 220, 683, 290, 694 ActionDest: 798 Annotation: Subtype: Link Rect: 43, 671, 64, 683 ActionDest: 798 Annotation: Subtype: Link Rect: 257, 638, 292, 648 ActionDest: 798 Annotation: Subtype: Link Rect: 43, 626, 66, 637 ActionDest: 798 Annotation: Subtype: Link Rect: 70, 626, 90, 637 ActionDest: 798 Annotation: Subtype: Link Rect: 110, 615, 153, 626 ActionDest: 753 Annotation: Subtype: Link Rect: 155, 615, 175, 626 ActionDest: 753 Annotation: Subtype: Link Rect: 244, 431, 292, 442 ActionDest: 753 Annotation: Subtype: Link Rect: 43, 419, 68, 431 ActionDest: 753 Annotation: Subtype: Link Rect: 76, 419, 96, 431 ActionDest: 753 Annotation: Subtype: Link Rect: 103, 419, 158, 431 ActionDest: 798 Annotation: Subtype: Link Rect: 166, 419, 186, 431 ActionDest: 798 Annotation: Subtype: Link Rect: 140, 397, 182, 408 ActionDest: 824 Annotation: Subtype: Link Rect: 187, 397, 208, 408 ActionDest: 824 Annotation: Subtype: Link Rect: 247, 374, 290, 385 ActionDest: 753 Annotation: Subtype: Link Rect: 43, 362, 64, 373 ActionDest: 753 Annotation: Subtype: Link Rect: 159, 339, 201, 351 ActionDest: 753 Annotation: Subtype: Link Rect: 204, 339, 224, 351 ActionDest: 753 Annotation: Subtype: Link Rect: 228, 339, 266, 351 ActionDest: 753 Annotation: Subtype: Link Rect: 270, 339, 290, 351 ActionDest: 753 Annotation: Subtype: Link Rect: 43, 328, 64, 339 ActionDest: 753 Annotation: Subtype: Link Rect: 68, 328, 119, 339 ActionDest: 824 Annotation: Subtype: Link Rect: 124, 328, 144, 339 ActionDest: 824 Annotation: Subtype: Link Rect: 213, 213, 262, 225 ActionDest: 798 Annotation: Subtype: Link Rect: 267, 213, 287, 225 ActionDest: 798 Annotation: Subtype: Link Rect: 135, 179, 182, 190 ActionDest: 798 Annotation: Subtype: Link Rect: 188, 179, 208, 190 ActionDest: 798 Annotation: Subtype: Link Rect: 214, 179, 235, 190 ActionDest: 798 Annotation: Subtype: Link Rect: 352, 534, 394, 545 ActionDest: 753 Annotation: Subtype: Link Rect: 399, 534, 419, 545 ActionDest: 753 Annotation: Subtype: Link Rect: 486, 523, 549, 534 ActionDest: 798 Annotation: Subtype: Link Rect: 302, 511, 322, 522 ActionDest: 798 Annotation: Subtype: Link Rect: 523, 477, 551, 488 ActionDest: 798 Annotation: Subtype: Link Rect: 302, 465, 355, 477 ActionDest: 798 Annotation: Subtype: Link Rect: 360, 465, 380, 477 ActionDest: 798 Annotation: Subtype: Link Rect: 386, 465, 445, 477 ActionDest: 798 Annotation: Subtype: Link Rect: 451, 465, 471, 477 ActionDest: 798 Annotation: Subtype: Link Rect: 527, 374, 551, 385 ActionDest: 753 Annotation: Subtype: Link Rect: 302, 362, 345, 373 ActionDest: 753 Annotation: Subtype: Link Rect: 350, 362, 370, 373 ActionDest: 753 Annotation: Subtype: Link Rect: 375, 362, 440, 373 ActionDest: 753 Annotation: Subtype: Link Rect: 445, 362, 465, 373 ActionDest: 753 Annotation: Subtype: Link Rect: 512, 270, 551, 282 ActionDest: 753 Annotation: Subtype: Link Rect: 302, 259, 324, 270 ActionDest: 753 Annotation: Subtype: Link Rect: 329, 259, 349, 270 ActionDest: 753 Annotation: Subtype: Link Rect: 353, 259, 417, 270 ActionDest: 753 Annotation: Subtype: Link Rect: 421, 259, 442, 270 ActionDest: 753 Annotation: Subtype: Link Rect: 446, 259, 524, 270 ActionDest: 798 Annotation: Subtype: Link Rect: 528, 259, 549, 270 ActionDest: 798 Annotation: Subtype: Link Rect: 302, 248, 361, 259 ActionDest: 798 Annotation: Subtype: Link Rect: 364, 248, 384, 259 ActionDest: 798 Annotation: Subtype: Link Rect: 512, 236, 551, 247 ActionDest: 798 Annotation: Subtype: Link Rect: 302, 225, 324, 236 ActionDest: 798 Annotation: Subtype: Link Rect: 329, 225, 349, 236 ActionDest: 798 Annotation: Subtype: Link Rect: 354, 225, 409, 236 ActionDest: 753 Annotation: Subtype: Link Rect: 414, 225, 434, 236 ActionDest: 753 Annotation: Subtype: Link Rect: 438, 225, 521, 236 ActionDest: 753 Annotation: Subtype: Link Rect: 525, 225, 545, 236 ActionDest: 753 Annotation: Subtype: Link Rect: 305, 144, 357, 156 ActionDest: 753 Annotation: Subtype: Link Rect: 363, 144, 383, 156 ActionDest: 753 Annotation: Subtype: Link Rect: 389, 144, 455, 156 ActionDest: 753 Annotation: Subtype: Link Rect: 460, 144, 481, 156 ActionDest: 753 Annotation: Subtype: Link Rect: 486, 144, 523, 156 ActionDest: 753 Annotation: Subtype: Link Rect: 528, 144, 549, 156 ActionDest: 753 Annotation: Subtype: Link Rect: 302, 133, 347, 144 ActionDest: 798 Annotation: Subtype: Link Rect: 350, 133, 370, 144 ActionDest: 798 Annotation: Subtype: Link Rect: 326, 99, 389, 110 ActionDest: 753 Annotation: Subtype: Link Rect: 394, 99, 414, 110 ActionDest: 753 Annotation: Subtype: Link Rect: 419, 99, 483, 110 ActionDest: 753 Annotation: Subtype: Link Rect: 487, 99, 507, 110 ActionDest: 753 Annotation: Subtype: Link Rect: 512, 99, 551, 110 ActionDest: 798 Annotation: Subtype: Link Rect: 302, 87, 325, 99 ActionDest: 798 Annotation: Subtype: Link Rect: 330, 87, 350, 99 ActionDest: 798 Annotation: Subtype: Link Rect: 468, 87, 524, 99 ActionDest: 753 Annotation: Subtype: Link Rect: 528, 87, 549, 99 ActionDest: 753 Annotation: Subtype: Link Rect: 302, 77, 343, 87 ActionDest: 753 Annotation: Subtype: Link Rect: 349, 77, 369, 87 ActionDest: 753 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 432, 29, 551, 38 Page: Sequence: 14 Annotations: Annotation: Subtype: Link Rect: 117, 694, 179, 706 ActionDest: 798 Annotation: Subtype: Link Rect: 183, 694, 203, 706 ActionDest: 798 Annotation: Subtype: Link Rect: 47, 626, 97, 637 ActionDest: 798 Annotation: Subtype: Link Rect: 100, 626, 120, 637 ActionDest: 798 Annotation: Subtype: Link Rect: 218, 591, 265, 603 ActionDest: 753 Annotation: Subtype: Link Rect: 267, 591, 287, 603 ActionDest: 753 Annotation: Subtype: Link Rect: 215, 568, 265, 580 ActionDest: 753 Annotation: Subtype: Link Rect: 270, 568, 290, 580 ActionDest: 753 Annotation: Subtype: Link Rect: 43, 557, 100, 568 ActionDest: 690 Annotation: Subtype: Link Rect: 104, 557, 124, 568 ActionDest: 690 Annotation: Subtype: Link Rect: 127, 557, 213, 568 ActionDest: 798 Annotation: Subtype: Link Rect: 217, 557, 237, 568 ActionDest: 798 Annotation: Subtype: Link Rect: 241, 557, 290, 568 ActionDest: 824 Annotation: Subtype: Link Rect: 43, 545, 64, 557 ActionDest: 824 Annotation: Subtype: Link Rect: 203, 534, 290, 545 ActionDest: 690 Annotation: Subtype: Link Rect: 43, 523, 64, 534 ActionDest: 690 Annotation: Subtype: Link Rect: 574, 605, 576, 617 ActionDest: 5 Annotation: Subtype: Link Rect: 354, 324, 551, 335 Annotation: Subtype: Link Rect: 302, 312, 465, 324 Annotation: Subtype: Link Rect: 69, 99, 169, 108 Annotation: Subtype: Link Rect: 93, 71, 158, 80 Annotation: Subtype: Link Rect: 501, 127, 551, 136 Annotation: Subtype: Link Rect: 312, 119, 371, 127 Annotation: Subtype: Link Rect: 471, 99, 551, 108 Annotation: Subtype: Link Rect: 312, 90, 335, 98 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 432, 29, 551, 38 Page: Sequence: 15 Annotations: Annotation: Subtype: Link Rect: 119, 669, 237, 678 Annotation: Subtype: Link Rect: 53, 631, 153, 640 Annotation: Subtype: Link Rect: 156, 593, 258, 602 Annotation: Subtype: Link Rect: 213, 555, 293, 564 Annotation: Subtype: Link Rect: 53, 547, 95, 554 Annotation: Subtype: Link Rect: 197, 517, 293, 526 Annotation: Subtype: Link Rect: 53, 509, 70, 516 Annotation: Subtype: Link Rect: 248, 441, 293, 451 Annotation: Subtype: Link Rect: 53, 434, 93, 441 Annotation: Subtype: Link Rect: 172, 404, 293, 413 Annotation: Subtype: Link Rect: 53, 396, 77, 403 Annotation: Subtype: Link Rect: 183, 328, 259, 337 Annotation: Subtype: Link Rect: 214, 280, 293, 290 Annotation: Subtype: Link Rect: 53, 273, 76, 280 Annotation: Subtype: Link Rect: 227, 233, 293, 243 Annotation: Subtype: Link Rect: 53, 224, 91, 232 Annotation: Subtype: Link Rect: 122, 195, 216, 205 Annotation: Subtype: Link Rect: 240, 138, 293, 148 Annotation: Subtype: Link Rect: 53, 131, 75, 138 Annotation: Subtype: Link Rect: 53, 74, 155, 82 Annotation: Subtype: Link Rect: 471, 688, 551, 697 Annotation: Subtype: Link Rect: 312, 680, 334, 687 Annotation: Subtype: Link Rect: 479, 650, 551, 659 Annotation: Subtype: Link Rect: 312, 642, 355, 649 Annotation: Subtype: Link Rect: 407, 602, 494, 612 Annotation: Subtype: Link Rect: 322, 565, 410, 574 Annotation: Subtype: Link Rect: 328, 527, 446, 536 Annotation: Subtype: Link Rect: 401, 470, 487, 479 Annotation: Subtype: Link Rect: 341, 451, 481, 460 Annotation: Subtype: Link Rect: 387, 395, 487, 403 Annotation: Subtype: Link Rect: 526, 318, 551, 328 Annotation: Subtype: Link Rect: 312, 310, 377, 318 Annotation: Subtype: Link Rect: 335, 282, 414, 290 Annotation: Subtype: Link Rect: 312, 243, 412, 252 Annotation: Subtype: Link Rect: 503, 205, 551, 214 Annotation: Subtype: Link Rect: 312, 195, 391, 205 Annotation: Subtype: Link Rect: 361, 167, 475, 176 Annotation: Subtype: Link Rect: 470, 138, 551, 148 Annotation: Subtype: Link Rect: 312, 131, 350, 138 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 432, 29, 551, 38 Page: Sequence: 16 Annotations: Annotation: Subtype: Link Rect: 93, 697, 197, 706 Annotation: Subtype: Link Rect: 252, 669, 293, 678 Annotation: Subtype: Link Rect: 53, 659, 117, 668 Annotation: Subtype: Link Rect: 154, 583, 258, 593 Annotation: Subtype: Link Rect: 199, 545, 283, 555 Annotation: Subtype: Link Rect: 183, 517, 286, 526 Annotation: Subtype: Link Rect: 70, 366, 162, 375 Annotation: Subtype: Link Rect: 143, 300, 243, 309 Annotation: Subtype: Link Rect: 142, 262, 264, 271 Annotation: Subtype: Link Rect: 209, 243, 293, 252 Annotation: Subtype: Link Rect: 53, 235, 75, 242 Annotation: Subtype: Link Rect: 100, 205, 215, 214 Annotation: Subtype: Link Rect: 94, 167, 162, 176 Annotation: Subtype: Link Rect: 68, 120, 171, 129 Annotation: Subtype: Link Rect: 279, 91, 293, 101 Annotation: Subtype: Link Rect: 53, 82, 154, 91 Annotation: Subtype: Link Rect: 510, 687, 551, 697 Annotation: Subtype: Link Rect: 312, 678, 366, 687 Annotation: Subtype: Link Rect: 477, 650, 551, 659 Annotation: Subtype: Link Rect: 312, 642, 350, 649 Annotation: Subtype: Link Rect: 341, 602, 443, 612 Annotation: Subtype: Link Rect: 472, 546, 551, 555 Annotation: Subtype: Link Rect: 312, 537, 335, 545 Annotation: Subtype: Link Rect: 371, 509, 468, 517 Annotation: Subtype: Link Rect: 469, 480, 551, 489 Annotation: Subtype: Link Rect: 312, 472, 334, 478 Annotation: Subtype: Link Rect: 526, 441, 551, 451 Annotation: Subtype: Link Rect: 312, 432, 412, 441 Annotation: Subtype: Link Rect: 378, 328, 480, 337 Annotation: Subtype: Link Rect: 506, 290, 551, 299 Annotation: Subtype: Link Rect: 312, 281, 372, 290 Annotation: Subtype: Link Rect: 341, 243, 450, 252 Annotation: Subtype: Link Rect: 526, 214, 551, 224 Annotation: Subtype: Link Rect: 312, 205, 396, 214 Annotation: Subtype: Link Rect: 472, 148, 551, 157 Annotation: Subtype: Link Rect: 312, 139, 335, 147 Annotation: Subtype: Link Rect: 348, 83, 420, 91 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 432, 29, 551, 38 Page: Sequence: 17 Annotations: Annotation: Subtype: Link Rect: 111, 687, 214, 697 Annotation: Subtype: Link Rect: 158, 660, 250, 668 Annotation: Subtype: Link Rect: 147, 632, 246, 640 Annotation: Subtype: Link Rect: 110, 593, 216, 602 Annotation: Subtype: Link Rect: 316, 641, 343, 649 Annotation: Subtype: Link Rect: 346, 641, 378, 649 Annotation: Subtype: Link Rect: 381, 641, 416, 649 Annotation: Subtype: Link Rect: 420, 641, 443, 649 Annotation: Subtype: Link Rect: 446, 641, 476, 649 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 432, 29, 551, 38 Checksum: 2710cac5 Type: CRC32 Checksum: 5625c8b67fdbdb4454697fdae527415c Type: MD5 Checksum: 8736614874bc89c1e0f60b73edc0a220e032acdf Type: SHA-1