796b3db80f2daaf98bec6b6d919ff3ea pmc_34069117.pdf 77ef03fea930f75a2bfaf58efca3483fb3267793 pmc_34069117.pdf e3e98ca34be28507eeff89f3cb6f8ab7af7c3136c97ff49b7acbea242fbe9ca3 pmc_34069117.pdf Title: Sodium Butyrate More Effectively Mitigates the Negative Effects of High-Concentrate Diet in Dairy Cows than Sodium -Hydroxybutyrate via Reducing Free Bacterial Cell Wall Components in Rumen Fluid and Plasma Subject: The present study was aimed at investigating the effects of sodium butyrate and sodium -hydroxybutyrate on lactation and health of dairy cows fed a high-concentrate (HC) diet. Eighty mid-lactation dairy cows with an average milk yield of 33.75 5.22 kg/d were randomly allocated to four groups (n = 20 per group) and were fed either a low-concentrate (LC) diet, a HC diet, the HC diet with 1% sodium butyrate (HCSB), or the HC diet with 1% sodium -hydroxybutyrate (HCHB). The feeding trial lasted for 7 weeks, with a 2-week adaptation period and a 5-week measurement period, and the trial started from 96 13 d in milk. Sodium butyrate supplementation delayed the decline in milk production and improved milk synthesis efficiency and milk fat content. Additionally, it decreased the proinflammatory cytokines and acute phase proteins (APPs) in plasma, the leucocytes in blood, the somatic cell count (SCC) in milk, and the gene expression of pattern recognition receptors (PRRs) and proinflammatory cytokines in the mammary gland, due to decreasing the contents of bacterial cell wall components (lipopolysaccharide, LPS; peptidoglycan, PGN; and lipoteichoic acid, LTA) in the rumen and plasma, compared with the HC diet. Sodium -hydroxybutyrate supplementation also improved milk yield, milk synthesis efficiency and milk fat content and partially reduced the adverse effects caused by the HC diet, but it had no effect on decreasing bacterial cell wall components in the rumen and plasma, compared with the HC diet. Collectively, both sodium butyrate and sodium -hydroxybutyrate mitigated the negative effects of HC diet on lactation and health of dairy cows, with sodium butyrate being more effective than sodium -hydroxybutyrate. Keywords: sodium butyrate; sodium -hydroxybutyrate; lipopolysaccharide; peptidoglycan; lipoteichoic acid; dairy cows Author: Yongjiang Wu, Yawang Sun, Ruiming Zhang, Tianle He, Guohao Huang, Ke Tian, Junhui Liu, Juncai Chen and Guozhong Dong Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Fri May 14 14:15:28 2021 CEST ModDate: Fri May 14 14:15:28 2021 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 16 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 1742381 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- GBHWYW+URWPalladioL-Ital Type 1 Custom yes yes no 165 0 AFEDYI+URWPalladioL-Bold Type 1 Custom yes yes no 166 0 IUOUHH+PazoMath-BoldItalic Type 1 Builtin yes yes no 167 0 AZVUUO+URWPalladioL-Roma Type 1 Custom yes yes no 168 0 DUJUUF+PazoMath-Italic Type 1 Builtin yes yes no 169 0 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ABCDEE+Palatino Linotype TrueType WinAnsi yes yes no 334 0 ABCDEE+Palatino Linotype,Italic TrueType WinAnsi yes yes no 335 0 ABCDEE+Palatino Linotype,BoldItalic TrueType WinAnsi yes yes no 336 0 ABCDEE+Palatino Linotype,Italic CID TrueType Identity-H yes yes yes 337 0 ABCDEE+Palatino Linotype CID TrueType Identity-H yes yes yes 338 0 ABCDEE+Palatino Linotype,Bold TrueType WinAnsi yes yes no 452 0 ABCDEE+Palatino Linotype TrueType WinAnsi yes yes no 453 0 ABCDEE+Palatino Linotype,Italic TrueType WinAnsi yes yes no 454 0 ABCDEE+Palatino Linotype,Italic CID TrueType Identity-H yes yes yes 455 0 ABCDEE+Palatino Linotype CID TrueType Identity-H yes yes yes 456 0 MPUDFL+PazoMath Type 1 Builtin yes yes no 550 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-05-27 02:44:30 CEST RepresentationInformation: pmc_34069117.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-03-31 12:14:02 CEST Size: 1742381 Format: PDF Version: 1.5 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 0 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: ぉのぴひはつふっぴどはのぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸲ Item: Title: げづびふぬぴびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮ㄩ‾㸊⡜㌷㙜㌷㝜〰ぐひはつふっぴどはのぜ〴ぜ〰ぐづひてはひねちのっづぜ〴ぜ〰ちのつぜ〴ぜ〰きどぬにぜ〴ぜ〰ぃはねばはのづのぴびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㈩‾㸊⡜㌷㙜㌷㝜〰げふねづのぜ〴ぜ〰ばえぜ〴ぜ〰ちのつぜ〴ぜ〰ぴとづぜ〴ぜ〰ぃはのっづのぴひちぴどはのびぜ〴ぜ〰はてぜ〴ぜ〰がぐこ〬ぜ〴ぜ〰ぐぇぎぜ〴ぜ〰ちのつぜ〴ぜ〰がごぁぜ〴ぜ〰どのぜ〴ぜ〰げふねづのぜ〴ぜ〰うぬふどつぜ〴ぜ〰ちのつぜ〴ぜ〰ぐぬちびねちぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㌩‾㸊⡜㌷㙜㌷㝜〰ぃはのっづのぴひちぴどはのびぜ〴ぜ〰はてぜ〴ぜ〰ぐひはどのてぬちねねちぴはひべぜ〴ぜ〰ぃべぴはにどのづびぜ〴ぜ〰ちのつぜ〴ぜ〰ぁっふぴづぜ〴ぜ〰ぐとちびづぜ〴ぜ〰ぐひはぴづどのびぜ〴ぜ〰ぜ〵ぜ〰ぁぐぐびぜ〵ㅜ〰ぜ〴ぜ〰どのぜ〴ぜ〰ぐぬちびねちぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㐩‾㸊⡜㌷㙜㌷㝜〰あぬははつぜ〴ぜ〰がづふっはっべぴづぜ〴ぜ〰ぉのつづへづびぜ〴ぜ〰ちのつぜ〴ぜ〰きどぬにぜ〴ぜ〰こはねちぴどっぜ〴ぜ〰ぃづぬぬぜ〴ぜ〰ぃはふのぴぜ〴ぜ〰ぜ〵ぜ〰こぃぃぜ〵ㅜ〰ぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㔩‾㸊⡜㌷㙜㌷㝜〰あぬははつぜ〴ぜ〰ぇぬふっはびづぜ〴ぜ〰ちのつぜ〴ぜ〰あぬははつぜ〴ぜ〰かづぴはのづぜ〴ぜ〰あはつどづびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㘩‾㸊⡜㌷㙜㌷㝜〰ぇづのづぜ〴ぜ〰ぅへばひづびびどはのぜ〴ぜ〰はてぜ〴ぜ〰ぐげげびぜ〴ぜ〰ちのつぜ〴ぜ〰ぐひはどのてぬちねねちぴはひべぜ〴ぜ〰ぃべぴはにどのづびぜ〴ぜ〰どのぜ〴ぜ〰きどぬにぜ〴ぜ〰こはねちぴどっぜ〴ぜ〰ぃづぬぬびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸳ Children: Item: Title: ぐひはつふっぴどはのぜ〴ぜ〰ぐづひてはひねちのっづぜ〴ぜ〰ちのつぜ〴ぜ〰きどぬにぜ〴ぜ〰ぃはねばはのづのぴびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㈩‾㸊⡜㌷㙜㌷㝜〰げふねづのぜ〴ぜ〰ばえぜ〴ぜ〰ちのつぜ〴ぜ〰ぴとづぜ〴ぜ〰ぃはのっづのぴひちぴどはのびぜ〴ぜ〰はてぜ〴ぜ〰がぐこ〬ぜ〴ぜ〰ぐぇぎぜ〴ぜ〰ちのつぜ〴ぜ〰がごぁぜ〴ぜ〰どのぜ〴ぜ〰げふねづのぜ〴ぜ〰うぬふどつぜ〴ぜ〰ちのつぜ〴ぜ〰ぐぬちびねちぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㌩‾㸊⡜㌷㙜㌷㝜〰ぃはのっづのぴひちぴどはのびぜ〴ぜ〰はてぜ〴ぜ〰ぐひはどのてぬちねねちぴはひべぜ〴ぜ〰ぃべぴはにどのづびぜ〴ぜ〰ちのつぜ〴ぜ〰ぁっふぴづぜ〴ぜ〰ぐとちびづぜ〴ぜ〰ぐひはぴづどのびぜ〴ぜ〰ぜ〵ぜ〰ぁぐぐびぜ〵ㅜ〰ぜ〴ぜ〰どのぜ〴ぜ〰ぐぬちびねちぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㐩‾㸊⡜㌷㙜㌷㝜〰あぬははつぜ〴ぜ〰がづふっはっべぴづぜ〴ぜ〰ぉのつづへづびぜ〴ぜ〰ちのつぜ〴ぜ〰きどぬにぜ〴ぜ〰こはねちぴどっぜ〴ぜ〰ぃづぬぬぜ〴ぜ〰ぃはふのぴぜ〴ぜ〰ぜ〵ぜ〰こぃぃぜ〵ㅜ〰ぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㔩‾㸊⡜㌷㙜㌷㝜〰あぬははつぜ〴ぜ〰ぇぬふっはびづぜ〴ぜ〰ちのつぜ〴ぜ〰あぬははつぜ〴ぜ〰かづぴはのづぜ〴ぜ〰あはつどづびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㘩‾㸊⡜㌷㙜㌷㝜〰ぇづのづぜ〴ぜ〰ぅへばひづびびどはのぜ〴ぜ〰はてぜ〴ぜ〰ぐげげびぜ〴ぜ〰ちのつぜ〴ぜ〰ぐひはどのてぬちねねちぴはひべぜ〴ぜ〰ぃべぴはにどのづびぜ〴ぜ〰どのぜ〴ぜ〰きどぬにぜ〴ぜ〰こはねちぴどっぜ〴ぜ〰ぃづぬぬびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸳ Item: Title: げふねづのぜ〴ぜ〰ばえぜ〴ぜ〰ちのつぜ〴ぜ〰ぴとづぜ〴ぜ〰ぃはのっづのぴひちぴどはのびぜ〴ぜ〰はてぜ〴ぜ〰がぐこ〬ぜ〴ぜ〰ぐぇぎぜ〴ぜ〰ちのつぜ〴ぜ〰がごぁぜ〴ぜ〰どのぜ〴ぜ〰げふねづのぜ〴ぜ〰うぬふどつぜ〴ぜ〰ちのつぜ〴ぜ〰ぐぬちびねちぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㌩‾㸊⡜㌷㙜㌷㝜〰ぃはのっづのぴひちぴどはのびぜ〴ぜ〰はてぜ〴ぜ〰ぐひはどのてぬちねねちぴはひべぜ〴ぜ〰ぃべぴはにどのづびぜ〴ぜ〰ちのつぜ〴ぜ〰ぁっふぴづぜ〴ぜ〰ぐとちびづぜ〴ぜ〰ぐひはぴづどのびぜ〴ぜ〰ぜ〵ぜ〰ぁぐぐびぜ〵ㅜ〰ぜ〴ぜ〰どのぜ〴ぜ〰ぐぬちびねちぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㐩‾㸊⡜㌷㙜㌷㝜〰あぬははつぜ〴ぜ〰がづふっはっべぴづぜ〴ぜ〰ぉのつづへづびぜ〴ぜ〰ちのつぜ〴ぜ〰きどぬにぜ〴ぜ〰こはねちぴどっぜ〴ぜ〰ぃづぬぬぜ〴ぜ〰ぃはふのぴぜ〴ぜ〰ぜ〵ぜ〰こぃぃぜ〵ㅜ〰ぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㔩‾㸊⡜㌷㙜㌷㝜〰あぬははつぜ〴ぜ〰ぇぬふっはびづぜ〴ぜ〰ちのつぜ〴ぜ〰あぬははつぜ〴ぜ〰かづぴはのづぜ〴ぜ〰あはつどづびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㘩‾㸊⡜㌷㙜㌷㝜〰ぇづのづぜ〴ぜ〰ぅへばひづびびどはのぜ〴ぜ〰はてぜ〴ぜ〰ぐげげびぜ〴ぜ〰ちのつぜ〴ぜ〰ぐひはどのてぬちねねちぴはひべぜ〴ぜ〰ぃべぴはにどのづびぜ〴ぜ〰どのぜ〴ぜ〰きどぬにぜ〴ぜ〰こはねちぴどっぜ〴ぜ〰ぃづぬぬびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸳ Item: Title: ぃはのっづのぴひちぴどはのびぜ〴ぜ〰はてぜ〴ぜ〰ぐひはどのてぬちねねちぴはひべぜ〴ぜ〰ぃべぴはにどのづびぜ〴ぜ〰ちのつぜ〴ぜ〰ぁっふぴづぜ〴ぜ〰ぐとちびづぜ〴ぜ〰ぐひはぴづどのびぜ〴ぜ〰ぜ〵ぜ〰ぁぐぐびぜ〵ㅜ〰ぜ〴ぜ〰どのぜ〴ぜ〰ぐぬちびねちぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㐩‾㸊⡜㌷㙜㌷㝜〰あぬははつぜ〴ぜ〰がづふっはっべぴづぜ〴ぜ〰ぉのつづへづびぜ〴ぜ〰ちのつぜ〴ぜ〰きどぬにぜ〴ぜ〰こはねちぴどっぜ〴ぜ〰ぃづぬぬぜ〴ぜ〰ぃはふのぴぜ〴ぜ〰ぜ〵ぜ〰こぃぃぜ〵ㅜ〰ぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㔩‾㸊⡜㌷㙜㌷㝜〰あぬははつぜ〴ぜ〰ぇぬふっはびづぜ〴ぜ〰ちのつぜ〴ぜ〰あぬははつぜ〴ぜ〰かづぴはのづぜ〴ぜ〰あはつどづびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㘩‾㸊⡜㌷㙜㌷㝜〰ぇづのづぜ〴ぜ〰ぅへばひづびびどはのぜ〴ぜ〰はてぜ〴ぜ〰ぐげげびぜ〴ぜ〰ちのつぜ〴ぜ〰ぐひはどのてぬちねねちぴはひべぜ〴ぜ〰ぃべぴはにどのづびぜ〴ぜ〰どのぜ〴ぜ〰きどぬにぜ〴ぜ〰こはねちぴどっぜ〴ぜ〰ぃづぬぬびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸳ Item: Title: あぬははつぜ〴ぜ〰がづふっはっべぴづぜ〴ぜ〰ぉのつづへづびぜ〴ぜ〰ちのつぜ〴ぜ〰きどぬにぜ〴ぜ〰こはねちぴどっぜ〴ぜ〰ぃづぬぬぜ〴ぜ〰ぃはふのぴぜ〴ぜ〰ぜ〵ぜ〰こぃぃぜ〵ㅜ〰ぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㔩‾㸊⡜㌷㙜㌷㝜〰あぬははつぜ〴ぜ〰ぇぬふっはびづぜ〴ぜ〰ちのつぜ〴ぜ〰あぬははつぜ〴ぜ〰かづぴはのづぜ〴ぜ〰あはつどづびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㘩‾㸊⡜㌷㙜㌷㝜〰ぇづのづぜ〴ぜ〰ぅへばひづびびどはのぜ〴ぜ〰はてぜ〴ぜ〰ぐげげびぜ〴ぜ〰ちのつぜ〴ぜ〰ぐひはどのてぬちねねちぴはひべぜ〴ぜ〰ぃべぴはにどのづびぜ〴ぜ〰どのぜ〴ぜ〰きどぬにぜ〴ぜ〰こはねちぴどっぜ〴ぜ〰ぃづぬぬびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸳ Item: Title: あぬははつぜ〴ぜ〰ぇぬふっはびづぜ〴ぜ〰ちのつぜ〴ぜ〰あぬははつぜ〴ぜ〰かづぴはのづぜ〴ぜ〰あはつどづびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㈮㘩‾㸊⡜㌷㙜㌷㝜〰ぇづのづぜ〴ぜ〰ぅへばひづびびどはのぜ〴ぜ〰はてぜ〴ぜ〰ぐげげびぜ〴ぜ〰ちのつぜ〴ぜ〰ぐひはどのてぬちねねちぴはひべぜ〴ぜ〰ぃべぴはにどのづびぜ〴ぜ〰どのぜ〴ぜ〰きどぬにぜ〴ぜ〰こはねちぴどっぜ〴ぜ〰ぃづぬぬびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸳ Item: Title: ぇづのづぜ〴ぜ〰ぅへばひづびびどはのぜ〴ぜ〰はてぜ〴ぜ〰ぐげげびぜ〴ぜ〰ちのつぜ〴ぜ〰ぐひはどのてぬちねねちぴはひべぜ〴ぜ〰ぃべぴはにどのづびぜ〴ぜ〰どのぜ〴ぜ〰きどぬにぜ〴ぜ〰こはねちぴどっぜ〴ぜ〰ぃづぬぬびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸳ Item: Title: いどびっふびびどはのぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸴ Item: Title: ぃはのっぬふびどはのびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳散瑩潮⸵ Item: Title: きちぴづひどちぬびぜ〴ぜ〰ちのつぜ〴ぜ〰きづぴとはつびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮ㄩ‾㸊⡜㌷㙜㌷㝜〰ぅぴとどっびぜ〴ぜ〰こぴちぴづねづのぴぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㈩‾㸊⡜㌷㙜㌷㝜〰ぃとづねどっちぬびぜ〴ぜ〰ちのつぜ〴ぜ〰げづちでづのぴびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㌩‾㸊⡜㌷㙜㌷㝜〰ぅへばづひどねづのぴちぬぜ〴ぜ〰いづびどでの〬ぜ〴ぜ〰いちどひべぜ〴ぜ〰ぃはぷび〬ぜ〴ぜ〰ちのつぜ〴ぜ〰いどづぴびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㐩‾㸊⡜㌷㙜㌷㝜〰こちねばぬづぜ〴ぜ〰ぃはぬぬづっぴどはのぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㔩‾㸊⡜㌷㙜㌷㝜〰ぐひはつふっぴどはのぜ〴ぜ〰ぐづひてはひねちのっづぜ〴ぜ〰きづちびふひづねづのぴぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㘩‾㸊⡜㌷㙜㌷㝜〰きづちびふひづねづのぴぜ〴ぜ〰はてぜ〴ぜ〰あちっぴづひどちぬぜ〴ぜ〰ぃづぬぬぜ〴ぜ〰しちぬぬぜ〴ぜ〰ぃはねばはのづのぴびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㜩‾㸊⡜㌷㙜㌷㝜〰いづぴづっぴどはのぜ〴ぜ〰はてぜ〴ぜ〰ぐひはどのてぬちねねちぴはひべぜ〴ぜ〰ぃべぴはにどのづびぜ〴ぜ〰ちのつぜ〴ぜ〰ぁぐぐびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㠩‾㸊⡜㌷㙜㌷㝜〰きづちびふひづねづのぴびぜ〴ぜ〰はてぜ〴ぜ〰あぬははつぜ〴ぜ〰がづふっはっべぴづぜ〴ぜ〰ぉのつづへづびぜ〴ぜ〰ちのつぜ〴ぜ〰きどぬにぜ〴ぜ〰こぃぃぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㤩‾㸊⡜㌷㙜㌷㝜〰いづぴづっぴどはのぜ〴ぜ〰はてぜ〴ぜ〰あぬははつぜ〴ぜ〰ぇぬふっはびづぜ〴ぜ〰ちのつぜ〴ぜ〰あぬははつぜ〴ぜ〰かづぴはのづぜ〴ぜ〰あはつどづびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㄰ Children: Item: Title: ぅぴとどっびぜ〴ぜ〰こぴちぴづねづのぴぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㈩‾㸊⡜㌷㙜㌷㝜〰ぃとづねどっちぬびぜ〴ぜ〰ちのつぜ〴ぜ〰げづちでづのぴびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㌩‾㸊⡜㌷㙜㌷㝜〰ぅへばづひどねづのぴちぬぜ〴ぜ〰いづびどでの〬ぜ〴ぜ〰いちどひべぜ〴ぜ〰ぃはぷび〬ぜ〴ぜ〰ちのつぜ〴ぜ〰いどづぴびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㐩‾㸊⡜㌷㙜㌷㝜〰こちねばぬづぜ〴ぜ〰ぃはぬぬづっぴどはのぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㔩‾㸊⡜㌷㙜㌷㝜〰ぐひはつふっぴどはのぜ〴ぜ〰ぐづひてはひねちのっづぜ〴ぜ〰きづちびふひづねづのぴぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㘩‾㸊⡜㌷㙜㌷㝜〰きづちびふひづねづのぴぜ〴ぜ〰はてぜ〴ぜ〰あちっぴづひどちぬぜ〴ぜ〰ぃづぬぬぜ〴ぜ〰しちぬぬぜ〴ぜ〰ぃはねばはのづのぴびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㜩‾㸊⡜㌷㙜㌷㝜〰いづぴづっぴどはのぜ〴ぜ〰はてぜ〴ぜ〰ぐひはどのてぬちねねちぴはひべぜ〴ぜ〰ぃべぴはにどのづびぜ〴ぜ〰ちのつぜ〴ぜ〰ぁぐぐびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㠩‾㸊⡜㌷㙜㌷㝜〰きづちびふひづねづのぴびぜ〴ぜ〰はてぜ〴ぜ〰あぬははつぜ〴ぜ〰がづふっはっべぴづぜ〴ぜ〰ぉのつづへづびぜ〴ぜ〰ちのつぜ〴ぜ〰きどぬにぜ〴ぜ〰こぃぃぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㤩‾㸊⡜㌷㙜㌷㝜〰いづぴづっぴどはのぜ〴ぜ〰はてぜ〴ぜ〰あぬははつぜ〴ぜ〰ぇぬふっはびづぜ〴ぜ〰ちのつぜ〴ぜ〰あぬははつぜ〴ぜ〰かづぴはのづぜ〴ぜ〰あはつどづびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㄰ Item: Title: ぃとづねどっちぬびぜ〴ぜ〰ちのつぜ〴ぜ〰げづちでづのぴびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㌩‾㸊⡜㌷㙜㌷㝜〰ぅへばづひどねづのぴちぬぜ〴ぜ〰いづびどでの〬ぜ〴ぜ〰いちどひべぜ〴ぜ〰ぃはぷび〬ぜ〴ぜ〰ちのつぜ〴ぜ〰いどづぴびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㐩‾㸊⡜㌷㙜㌷㝜〰こちねばぬづぜ〴ぜ〰ぃはぬぬづっぴどはのぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㔩‾㸊⡜㌷㙜㌷㝜〰ぐひはつふっぴどはのぜ〴ぜ〰ぐづひてはひねちのっづぜ〴ぜ〰きづちびふひづねづのぴぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㘩‾㸊⡜㌷㙜㌷㝜〰きづちびふひづねづのぴぜ〴ぜ〰はてぜ〴ぜ〰あちっぴづひどちぬぜ〴ぜ〰ぃづぬぬぜ〴ぜ〰しちぬぬぜ〴ぜ〰ぃはねばはのづのぴびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㜩‾㸊⡜㌷㙜㌷㝜〰いづぴづっぴどはのぜ〴ぜ〰はてぜ〴ぜ〰ぐひはどのてぬちねねちぴはひべぜ〴ぜ〰ぃべぴはにどのづびぜ〴ぜ〰ちのつぜ〴ぜ〰ぁぐぐびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㠩‾㸊⡜㌷㙜㌷㝜〰きづちびふひづねづのぴびぜ〴ぜ〰はてぜ〴ぜ〰あぬははつぜ〴ぜ〰がづふっはっべぴづぜ〴ぜ〰ぉのつづへづびぜ〴ぜ〰ちのつぜ〴ぜ〰きどぬにぜ〴ぜ〰こぃぃぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㤩‾㸊⡜㌷㙜㌷㝜〰いづぴづっぴどはのぜ〴ぜ〰はてぜ〴ぜ〰あぬははつぜ〴ぜ〰ぇぬふっはびづぜ〴ぜ〰ちのつぜ〴ぜ〰あぬははつぜ〴ぜ〰かづぴはのづぜ〴ぜ〰あはつどづびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㄰ Item: Title: ぅへばづひどねづのぴちぬぜ〴ぜ〰いづびどでの〬ぜ〴ぜ〰いちどひべぜ〴ぜ〰ぃはぷび〬ぜ〴ぜ〰ちのつぜ〴ぜ〰いどづぴびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㐩‾㸊⡜㌷㙜㌷㝜〰こちねばぬづぜ〴ぜ〰ぃはぬぬづっぴどはのぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㔩‾㸊⡜㌷㙜㌷㝜〰ぐひはつふっぴどはのぜ〴ぜ〰ぐづひてはひねちのっづぜ〴ぜ〰きづちびふひづねづのぴぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㘩‾㸊⡜㌷㙜㌷㝜〰きづちびふひづねづのぴぜ〴ぜ〰はてぜ〴ぜ〰あちっぴづひどちぬぜ〴ぜ〰ぃづぬぬぜ〴ぜ〰しちぬぬぜ〴ぜ〰ぃはねばはのづのぴびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㜩‾㸊⡜㌷㙜㌷㝜〰いづぴづっぴどはのぜ〴ぜ〰はてぜ〴ぜ〰ぐひはどのてぬちねねちぴはひべぜ〴ぜ〰ぃべぴはにどのづびぜ〴ぜ〰ちのつぜ〴ぜ〰ぁぐぐびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㠩‾㸊⡜㌷㙜㌷㝜〰きづちびふひづねづのぴびぜ〴ぜ〰はてぜ〴ぜ〰あぬははつぜ〴ぜ〰がづふっはっべぴづぜ〴ぜ〰ぉのつづへづびぜ〴ぜ〰ちのつぜ〴ぜ〰きどぬにぜ〴ぜ〰こぃぃぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㤩‾㸊⡜㌷㙜㌷㝜〰いづぴづっぴどはのぜ〴ぜ〰はてぜ〴ぜ〰あぬははつぜ〴ぜ〰ぇぬふっはびづぜ〴ぜ〰ちのつぜ〴ぜ〰あぬははつぜ〴ぜ〰かづぴはのづぜ〴ぜ〰あはつどづびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㄰ Item: Title: こちねばぬづぜ〴ぜ〰ぃはぬぬづっぴどはのぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㔩‾㸊⡜㌷㙜㌷㝜〰ぐひはつふっぴどはのぜ〴ぜ〰ぐづひてはひねちのっづぜ〴ぜ〰きづちびふひづねづのぴぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㘩‾㸊⡜㌷㙜㌷㝜〰きづちびふひづねづのぴぜ〴ぜ〰はてぜ〴ぜ〰あちっぴづひどちぬぜ〴ぜ〰ぃづぬぬぜ〴ぜ〰しちぬぬぜ〴ぜ〰ぃはねばはのづのぴびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㜩‾㸊⡜㌷㙜㌷㝜〰いづぴづっぴどはのぜ〴ぜ〰はてぜ〴ぜ〰ぐひはどのてぬちねねちぴはひべぜ〴ぜ〰ぃべぴはにどのづびぜ〴ぜ〰ちのつぜ〴ぜ〰ぁぐぐびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㠩‾㸊⡜㌷㙜㌷㝜〰きづちびふひづねづのぴびぜ〴ぜ〰はてぜ〴ぜ〰あぬははつぜ〴ぜ〰がづふっはっべぴづぜ〴ぜ〰ぉのつづへづびぜ〴ぜ〰ちのつぜ〴ぜ〰きどぬにぜ〴ぜ〰こぃぃぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㤩‾㸊⡜㌷㙜㌷㝜〰いづぴづっぴどはのぜ〴ぜ〰はてぜ〴ぜ〰あぬははつぜ〴ぜ〰ぇぬふっはびづぜ〴ぜ〰ちのつぜ〴ぜ〰あぬははつぜ〴ぜ〰かづぴはのづぜ〴ぜ〰あはつどづびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㄰ Item: Title: ぐひはつふっぴどはのぜ〴ぜ〰ぐづひてはひねちのっづぜ〴ぜ〰きづちびふひづねづのぴぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㘩‾㸊⡜㌷㙜㌷㝜〰きづちびふひづねづのぴぜ〴ぜ〰はてぜ〴ぜ〰あちっぴづひどちぬぜ〴ぜ〰ぃづぬぬぜ〴ぜ〰しちぬぬぜ〴ぜ〰ぃはねばはのづのぴびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㜩‾㸊⡜㌷㙜㌷㝜〰いづぴづっぴどはのぜ〴ぜ〰はてぜ〴ぜ〰ぐひはどのてぬちねねちぴはひべぜ〴ぜ〰ぃべぴはにどのづびぜ〴ぜ〰ちのつぜ〴ぜ〰ぁぐぐびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㠩‾㸊⡜㌷㙜㌷㝜〰きづちびふひづねづのぴびぜ〴ぜ〰はてぜ〴ぜ〰あぬははつぜ〴ぜ〰がづふっはっべぴづぜ〴ぜ〰ぉのつづへづびぜ〴ぜ〰ちのつぜ〴ぜ〰きどぬにぜ〴ぜ〰こぃぃぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㤩‾㸊⡜㌷㙜㌷㝜〰いづぴづっぴどはのぜ〴ぜ〰はてぜ〴ぜ〰あぬははつぜ〴ぜ〰ぇぬふっはびづぜ〴ぜ〰ちのつぜ〴ぜ〰あぬははつぜ〴ぜ〰かづぴはのづぜ〴ぜ〰あはつどづびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㄰ Item: Title: きづちびふひづねづのぴぜ〴ぜ〰はてぜ〴ぜ〰あちっぴづひどちぬぜ〴ぜ〰ぃづぬぬぜ〴ぜ〰しちぬぬぜ〴ぜ〰ぃはねばはのづのぴびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㜩‾㸊⡜㌷㙜㌷㝜〰いづぴづっぴどはのぜ〴ぜ〰はてぜ〴ぜ〰ぐひはどのてぬちねねちぴはひべぜ〴ぜ〰ぃべぴはにどのづびぜ〴ぜ〰ちのつぜ〴ぜ〰ぁぐぐびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㠩‾㸊⡜㌷㙜㌷㝜〰きづちびふひづねづのぴびぜ〴ぜ〰はてぜ〴ぜ〰あぬははつぜ〴ぜ〰がづふっはっべぴづぜ〴ぜ〰ぉのつづへづびぜ〴ぜ〰ちのつぜ〴ぜ〰きどぬにぜ〴ぜ〰こぃぃぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㤩‾㸊⡜㌷㙜㌷㝜〰いづぴづっぴどはのぜ〴ぜ〰はてぜ〴ぜ〰あぬははつぜ〴ぜ〰ぇぬふっはびづぜ〴ぜ〰ちのつぜ〴ぜ〰あぬははつぜ〴ぜ〰かづぴはのづぜ〴ぜ〰あはつどづびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㄰ Item: Title: いづぴづっぴどはのぜ〴ぜ〰はてぜ〴ぜ〰ぐひはどのてぬちねねちぴはひべぜ〴ぜ〰ぃべぴはにどのづびぜ〴ぜ〰ちのつぜ〴ぜ〰ぁぐぐびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㠩‾㸊⡜㌷㙜㌷㝜〰きづちびふひづねづのぴびぜ〴ぜ〰はてぜ〴ぜ〰あぬははつぜ〴ぜ〰がづふっはっべぴづぜ〴ぜ〰ぉのつづへづびぜ〴ぜ〰ちのつぜ〴ぜ〰きどぬにぜ〴ぜ〰こぃぃぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㤩‾㸊⡜㌷㙜㌷㝜〰いづぴづっぴどはのぜ〴ぜ〰はてぜ〴ぜ〰あぬははつぜ〴ぜ〰ぇぬふっはびづぜ〴ぜ〰ちのつぜ〴ぜ〰あぬははつぜ〴ぜ〰かづぴはのづぜ〴ぜ〰あはつどづびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㄰ Item: Title: きづちびふひづねづのぴびぜ〴ぜ〰はてぜ〴ぜ〰あぬははつぜ〴ぜ〰がづふっはっべぴづぜ〴ぜ〰ぉのつづへづびぜ〴ぜ〰ちのつぜ〴ぜ〰きどぬにぜ〴ぜ〰こぃぃぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㤩‾㸊⡜㌷㙜㌷㝜〰いづぴづっぴどはのぜ〴ぜ〰はてぜ〴ぜ〰あぬははつぜ〴ぜ〰ぇぬふっはびづぜ〴ぜ〰ちのつぜ〴ぜ〰あぬははつぜ〴ぜ〰かづぴはのづぜ〴ぜ〰あはつどづびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㄰ Item: Title: いづぴづっぴどはのぜ〴ぜ〰はてぜ〴ぜ〰あぬははつぜ〴ぜ〰ぇぬふっはびづぜ〴ぜ〰ちのつぜ〴ぜ〰あぬははつぜ〴ぜ〰かづぴはのづぜ〴ぜ〰あはつどづびぜ〴〩਼㰠⽓ 䝯呯 䐠⡳畢獥捴楯渮㔮㄰ Item: Title: 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